(41 nodes) Regulation of embryonic development network (Caenorhabditis brenneri)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

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protein homology

Your Input:
	CAEBREN_13034	Uncharacterized protein; Belongs to the DEAD box helicase family. (689 aa)
	Cbn-puf-5	CBN-PUF-5 protein. (548 aa)
	CAEBREN_31603	Uncharacterized protein. (849 aa)
	CAEBREN_10086	Tyrosine-protein kinase. (525 aa)
	Cbn-wrm-1	CBN-WRM-1 protein. (843 aa)
	CAEBREN_05138	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (338 aa)
	CAEBREN_10574	Protein kinase domain-containing protein. (700 aa)
	CAEBREN_00131	HMG box domain-containing protein. (308 aa)
	CAEBREN_23998	HMG box domain-containing protein. (429 aa)
	Cbn-mus-81	CBN-MUS-81 protein. (183 aa)
	Cbn-sig-7	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (428 aa)
	Cbn-imp-2	CBN-IMP-2 protein. (469 aa)
	CAEBREN_24516	Uncharacterized protein. (462 aa)
	CAEBREN_11761	ERCC4 domain-containing protein. (354 aa)
	CAEBREN_00259	Tetraspanin. (309 aa)
	CAEBREN_12314	HMG box domain-containing protein. (414 aa)
	CAEBREN_29074	HMG box domain-containing protein. (308 aa)
	CAEBREN_04060	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (168 aa)
	CAEBREN_13933	Uncharacterized protein. (429 aa)
	CAEBREN_09583	Uncharacterized protein. (481 aa)
	Cbn-cutl-20	CBN-CUTL-20 protein. (386 aa)
	CAEBREN_28220	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (292 aa)
	CAEBREN_30399	POB3_N domain-containing protein. (79 aa)
	CAEBREN_04942	HMG box domain-containing protein. (262 aa)
	CAEBREN_28521	Protein kinase domain-containing protein. (652 aa)
	CAEBREN_09878	Tetraspanin. (309 aa)
	CAEBREN_20719	ERCC4 domain-containing protein. (305 aa)
	CAEBREN_22760	Uncharacterized protein. (285 aa)
	Cbn-nmy-2	CBN-NMY-2 protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2003 aa)
	CAEBREN_24261	Uncharacterized protein. (429 aa)
	CAEBREN_25379	FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (699 aa)
	CAEBREN_32521	Protein kinase domain-containing protein. (717 aa)
	CAEBREN_01678	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (297 aa)
	CAEBREN_04712	Tyrosine-protein kinase. (525 aa)
	CAEBREN_26207	Protein disulfide-isomerase. (488 aa)
	CAEBREN_13226	Protein disulfide-isomerase. (488 aa)
	CAEBREN_25669	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (451 aa)
	CAEBREN_31046	Uncharacterized protein. (282 aa)
	Cbn-nmy-1	CBN-NMY-1 protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1957 aa)
	Cbn-tsp-14	Tetraspanin. (451 aa)
	Cbn-pac-1	CBN-PAC-1 protein. (1595 aa)

Your Current Organism:

Caenorhabditis brenneri

NCBI taxonomy Id: 135651
Other names: C. brenneri, Caenorhabditis CB5161, Caenorhabditis brenneri Sudhaus & Kiontke, 2007, Caenorhabditis n. sp. CB5161, Caenorhabditis sp. 1 CB5161, Caenorhabditis sp. 4 (CB5161, LKC28, SB129, SB280), Caenorhabditis sp. 4 (CE-II), Caenorhabditis sp. CB5161, Caenorhabditis sp. PB2801

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAEBREN_00131	CAEBREN_13226	G0NH69	G0P305	HMG box domain-containing protein.	Protein disulfide-isomerase.	0.583
CAEBREN_00131	CAEBREN_26207	G0NH69	G0P3K3	HMG box domain-containing protein.	Protein disulfide-isomerase.	0.583
CAEBREN_00131	Cbn-wrm-1	G0NH69	G0MPG2	HMG box domain-containing protein.	CBN-WRM-1 protein.	0.584
CAEBREN_00259	CAEBREN_04712	G0NUQ4	G0P982	Tetraspanin.	Tyrosine-protein kinase.	0.514
CAEBREN_00259	CAEBREN_10086	G0NUQ4	G0MNP2	Tetraspanin.	Tyrosine-protein kinase.	0.514
CAEBREN_00259	Cbn-tsp-14	G0NUQ4	G0M8C2	Tetraspanin.	Tetraspanin.	0.584
CAEBREN_01678	Cbn-nmy-1	G0PBP2	G0M6Z5	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	CBN-NMY-1 protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.679
CAEBREN_04060	Cbn-nmy-1	G0P1D8	G0M6Z5	Myosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	CBN-NMY-1 protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.679
CAEBREN_04712	CAEBREN_00259	G0P982	G0NUQ4	Tyrosine-protein kinase.	Tetraspanin.	0.514
CAEBREN_04712	CAEBREN_09878	G0P982	G0PIP6	Tyrosine-protein kinase.	Tetraspanin.	0.514
CAEBREN_04712	CAEBREN_13034	G0P982	G0MKL5	Tyrosine-protein kinase.	Uncharacterized protein; Belongs to the DEAD box helicase family.	0.606
CAEBREN_04712	CAEBREN_25669	G0P982	G0P2G5	Tyrosine-protein kinase.	Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex.	0.642
CAEBREN_04712	Cbn-tsp-14	G0P982	G0M8C2	Tyrosine-protein kinase.	Tetraspanin.	0.504
CAEBREN_04712	Cbn-wrm-1	G0P982	G0MPG2	Tyrosine-protein kinase.	CBN-WRM-1 protein.	0.570
CAEBREN_04942	CAEBREN_13226	G0PM71	G0P305	HMG box domain-containing protein.	Protein disulfide-isomerase.	0.583
CAEBREN_04942	CAEBREN_26207	G0PM71	G0P3K3	HMG box domain-containing protein.	Protein disulfide-isomerase.	0.583
CAEBREN_04942	Cbn-wrm-1	G0PM71	G0MPG2	HMG box domain-containing protein.	CBN-WRM-1 protein.	0.584
CAEBREN_05138	Cbn-nmy-1	G0N6P3	G0M6Z5	Uncharacterized protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	CBN-NMY-1 protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family.	0.686
CAEBREN_09583	CAEBREN_11761	G0PD46	G0NT62	Uncharacterized protein.	ERCC4 domain-containing protein.	0.529
CAEBREN_09583	CAEBREN_20719	G0PD46	G0PD48	Uncharacterized protein.	ERCC4 domain-containing protein.	0.421

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