(96 nodes) Positive regulation of developmental growth network (Caenorhabditis brenneri)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CAEBREN_05349	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa)
	CAEBREN_19846	Prohibitin. (275 aa)
	Cbn-unc-40	CBN-UNC-40 protein. (1420 aa)
	Cbn-dpy-1	CBN-DPY-1 protein. (1362 aa)
	CAEBREN_31083	Uncharacterized protein. (615 aa)
	Cbn-pmk-3	Mitogen-activated protein kinase. (469 aa)
	Cbn-daf-2	CBN-DAF-2 protein. (1937 aa)
	CAEBREN_14413	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (633 aa)
	CAEBREN_30434	Uncharacterized protein. (51 aa)
	CAEBREN_21755	Prohibitin. (195 aa)
	CAEBREN_18000	Nuclear receptor domain-containing protein. (326 aa)
	CAEBREN_16980	Uncharacterized protein. (493 aa)
	CAEBREN_28233	Uncharacterized protein. (900 aa)
	CAEBREN_14137	Uncharacterized protein. (790 aa)
	CAEBREN_31385	Uncharacterized protein. (169 aa)
	CAEBREN_09421	TGF_BETA_2 domain-containing protein. (370 aa)
	CAEBREN_00313	Uncharacterized protein. (811 aa)
	CAEBREN_23738	Uncharacterized protein. (545 aa)
	CAEBREN_30789	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (805 aa)
	CAEBREN_31903	Uncharacterized protein. (559 aa)
	CAEBREN_29153	Uncharacterized protein. (239 aa)
	CAEBREN_31160	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family. (329 aa)
	CAEBREN_20778	Uncharacterized protein. (811 aa)
	CAEBREN_30747	Uncharacterized protein. (5734 aa)
	Cbn-unc-44	CBN-UNC-44 protein. (808 aa)
	CAEBREN_05836	Fork-head domain-containing protein. (717 aa)
	CAEBREN_31806	Peptidase_S8 domain-containing protein. (182 aa)
	CAEBREN_13545	ZP domain-containing protein. (282 aa)
	Cbn-egl-21	CBN-EGL-21 protein. (483 aa)
	CAEBREN_30365	Uncharacterized protein. (828 aa)
	Cbn-zag-1	CBN-ZAG-1 protein. (615 aa)
	CAEBREN_02522	Peptidase M12B domain-containing protein. (1020 aa)
	Cbn-mek-1	CBN-MEK-1 protein. (339 aa)
	Cbn-sig-7	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides. (428 aa)
	CAEBREN_11272	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (681 aa)
	CAEBREN_02058	Uncharacterized protein. (1660 aa)
	Cbn-kpc-1	CBN-KPC-1 protein; Belongs to the peptidase S8 family. (691 aa)
	CAEBREN_07990	Fork-head domain-containing protein. (483 aa)
	CAEBREN_30726	Protein kinase domain-containing protein. (820 aa)
	CAEBREN_31133	Uncharacterized protein. (555 aa)
	Cbn-spc-1	CBN-SPC-1 protein. (2427 aa)
	Cbn-hst-6	Heparan-sulfate 6-O-sulfotransferase; 6-O-sulfation enzyme which catalyzes the transfer of sulfate from 3'-phosphoadenosine 5'-phosphosulfate (PAPS) to position 6 of the N-sulfoglucosamine residue (GlcNS) of heparan sulfate. (364 aa)
	Cbn-hse-5	CBN-HSE-5 protein. (616 aa)
	Cbn-fsn-1	CBN-FSN-1 protein. (331 aa)
	Cbn-sma-3	Dwarfin sma. (395 aa)
	CAEBREN_16590	Uncharacterized protein. (1806 aa)
	CAEBREN_25299	Uncharacterized protein. (316 aa)
	CAEBREN_11571	Uncharacterized protein. (5386 aa)
	Cbn-gld-3	CBN-GLD-3 protein. (961 aa)
	CAEBREN_19142	Uncharacterized protein. (416 aa)
	Cbn-egl-3	CBN-EGL-3 protein; Belongs to the peptidase S8 family. (652 aa)
	CAEBREN_08229	Uncharacterized protein. (1851 aa)
	Cbn-che-2	CBN-CHE-2 protein. (761 aa)
	CAEBREN_20457	Uncharacterized protein. (860 aa)
	Cbn-unc-10	CBN-UNC-10 protein. (1638 aa)
	Cbn-nol-1	CBN-NOL-1 protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (687 aa)
	CAEBREN_23529	Uncharacterized protein. (344 aa)
	CAEBREN_25494	Uncharacterized protein. (1253 aa)
	CAEBREN_29340	Uncharacterized protein. (413 aa)
	Cbn-pde-2	Phosphodiesterase. (805 aa)
	Cbn-sma-2	CBN-SMA-2 protein. (178 aa)
	Cbn-aex-5	CBN-AEX-5 protein. (424 aa)
	Cbn-lrp-1	CBN-LRP-1 protein. (4759 aa)
	CAEBREN_06207	Uncharacterized protein. (4169 aa)
	CAEBREN_31917	Uncharacterized protein. (70 aa)
	CAEBREN_26021	Uncharacterized protein. (801 aa)
	Cbn-sma-6	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (631 aa)
	CAEBREN_05504	Prohibitin. (294 aa)
	CAEBREN_16771	Uncharacterized protein. (86 aa)
	CAEBREN_12364	Uncharacterized protein. (86 aa)
	Cbn-dbl-1	CBN-DBL-1 protein. (371 aa)
	CAEBREN_09262	Thioredoxin domain-containing protein. (246 aa)
	Cbn-unc-53	CBN-UNC-53 protein. (1692 aa)
	Cbn-raga-1	CBN-RAGA-1 protein. (318 aa)
	CAEBREN_30646	Uncharacterized protein. (840 aa)
	CAEBREN_04127	SCP2 domain-containing protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (435 aa)
	Cbn-mlk-1	CBN-MLK-1 protein. (1054 aa)
	CAEBREN_20079	Uncharacterized protein. (815 aa)
	CAEBREN_19421	Uncharacterized protein. (885 aa)
	Cbn-daf-4	Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (767 aa)
	CAEBREN_30962	Uncharacterized protein. (313 aa)
	CAEBREN_21692	Uncharacterized protein. (1443 aa)
	CAEBREN_06253	Uncharacterized protein. (776 aa)
	Cbn-umps-1	CBN-UMPS-1 protein. (498 aa)
	CAEBREN_10065	Fe2OG dioxygenase domain-containing protein. (163 aa)
	CAEBREN_17699	Uncharacterized protein. (686 aa)
	Cbn-hst-2	CBN-HST-2 protein. (325 aa)
	Cbn-tsp-21	Tetraspanin. (305 aa)
	CAEBREN_10891	Uncharacterized protein. (2519 aa)
	Cbn-sma-5	CBN-SMA-5 protein; Belongs to the protein kinase superfamily. (462 aa)
	CAEBREN_30584	MH2 domain-containing protein. (240 aa)
	CAEBREN_18092	Uncharacterized protein. (153 aa)
	CAEBREN_28281	EGF-like domain-containing protein. (4402 aa)
	CAEBREN_28659	Uncharacterized protein. (465 aa)
	CAEBREN_23789	Uncharacterized protein. (1458 aa)
	CAEBREN_31444	Dwarfin sma. (619 aa)

Your Current Organism:

Caenorhabditis brenneri

NCBI taxonomy Id: 135651
Other names: C. brenneri, Caenorhabditis CB5161, Caenorhabditis brenneri Sudhaus & Kiontke, 2007, Caenorhabditis n. sp. CB5161, Caenorhabditis sp. 1 CB5161, Caenorhabditis sp. 4 (CB5161, LKC28, SB129, SB280), Caenorhabditis sp. 4 (CE-II), Caenorhabditis sp. CB5161, Caenorhabditis sp. PB2801

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAEBREN_00313	CAEBREN_02058	G0PLB9	G0NJQ0	Uncharacterized protein.	Uncharacterized protein.	0.632
CAEBREN_00313	CAEBREN_08229	G0PLB9	G0N858	Uncharacterized protein.	Uncharacterized protein.	0.407
CAEBREN_00313	CAEBREN_20457	G0PLB9	G0N6N6	Uncharacterized protein.	Uncharacterized protein.	0.442
CAEBREN_00313	CAEBREN_21692	G0PLB9	G0MNK6	Uncharacterized protein.	Uncharacterized protein.	0.922
CAEBREN_00313	CAEBREN_23738	G0PLB9	G0PLF0	Uncharacterized protein.	Uncharacterized protein.	0.632
CAEBREN_00313	Cbn-daf-2	G0PLB9	G0PDK2	Uncharacterized protein.	CBN-DAF-2 protein.	0.407
CAEBREN_00313	Cbn-unc-40	G0PLB9	G0P6F4	Uncharacterized protein.	CBN-UNC-40 protein.	0.922
CAEBREN_00313	Cbn-unc-53	G0PLB9	G0MVF8	Uncharacterized protein.	CBN-UNC-53 protein.	0.563
CAEBREN_02058	CAEBREN_00313	G0NJQ0	G0PLB9	Uncharacterized protein.	Uncharacterized protein.	0.632
CAEBREN_02058	CAEBREN_20778	G0NJQ0	G0NA99	Uncharacterized protein.	Uncharacterized protein.	0.632
CAEBREN_02058	CAEBREN_21692	G0NJQ0	G0MNK6	Uncharacterized protein.	Uncharacterized protein.	0.856
CAEBREN_02058	Cbn-unc-40	G0NJQ0	G0P6F4	Uncharacterized protein.	CBN-UNC-40 protein.	0.856
CAEBREN_02058	Cbn-unc-53	G0NJQ0	G0MVF8	Uncharacterized protein.	CBN-UNC-53 protein.	0.634
CAEBREN_02522	CAEBREN_09421	G0NL36	G0PL14	Peptidase M12B domain-containing protein.	TGF_BETA_2 domain-containing protein.	0.563
CAEBREN_02522	CAEBREN_10891	G0NL36	G0MHP3	Peptidase M12B domain-containing protein.	Uncharacterized protein.	0.580
CAEBREN_02522	CAEBREN_20457	G0NL36	G0N6N6	Peptidase M12B domain-containing protein.	Uncharacterized protein.	0.577
CAEBREN_02522	Cbn-dbl-1	G0NL36	G0MY06	Peptidase M12B domain-containing protein.	CBN-DBL-1 protein.	0.563
CAEBREN_04127	CAEBREN_31160	G0MSH1	G0NAP1	SCP2 domain-containing protein; Belongs to the short-chain dehydrogenases/reductases (SDR) family.	Uncharacterized protein; Belongs to the thiolase-like superfamily. Thiolase family.	0.999
CAEBREN_05349	CAEBREN_05836	G0P431	G0NVG7	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Fork-head domain-containing protein.	0.490
CAEBREN_05349	CAEBREN_07990	G0P431	G0NH75	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily.	Fork-head domain-containing protein.	0.490

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