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| | ffh | Signal recognition particle; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY. Belongs to the GTP-binding SRP family. SRP54 subfamily. (449 aa) |
| | valS | Hypothetical protein; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner; Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily. (897 aa) |
| | AII50326.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (72 aa) |
| | AII50624.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (244 aa) |
| | AII50897.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (100 aa) |
| | AII50898.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thioredoxin family. (102 aa) |
| | dnaK | Molecular chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family. (647 aa) |
| | AII51044.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (212 aa) |
| | AII51045.1 | ATP-dependent Clp protease ClpC; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ClpA/ClpB family. (873 aa) |
| | lysS | lysyl-tRNA synthetase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-II aminoacyl-tRNA synthetase family. (516 aa) |
| | AII51089.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (101 aa) |
| | tilS | Hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family. (443 aa) |
| | dnaJ | Molecular chaperone DnaJ; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, [...] (379 aa) |
| | grpE | Hypothetical protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dep [...] (188 aa) |
| | obg | Hypothetical protein; An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control. Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family. (360 aa) |
| | AII51150.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (658 aa) |
| | rnc | Hypothetical protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. (233 aa) |
| | rpsT | 30S ribosomal protein S20; Binds directly to 16S ribosomal RNA. (85 aa) |
| | rsmG | Hypothetical protein; Specifically methylates the N7 position of a guanine in 16S rRNA; Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family. (212 aa) |
| | AII51217.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (79 aa) |
| | atpD | F0F1 ATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits. (501 aa) |
| | rplY | Hypothetical protein; This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance. Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily. (190 aa) |
| | pth | Hypothetical protein; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. (188 aa) |
| | metG | methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation. (681 aa) |
| | AII51228.1 | GTP-binding protein TypA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (602 aa) |
| | AII51233.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class IV-like SAM-binding methyltransferase superfamily. RNA methyltransferase TrmH family. (267 aa) |
| | pheT | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. (811 aa) |
| | AII51342.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-I aminoacyl-tRNA synthetase family. (291 aa) |
| | clpB | Molecular chaperone ClpB; Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE; Belongs to the ClpA/ClpB family. (872 aa) |
| | aspS | aspartyl-tRNA synthetase; Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp- AMP and then transferred to the acceptor end of tRNA(Asp). Belongs to the class-II aminoacyl-tRNA synthetase family. Type 1 subfamily. (587 aa) |
| | AII51416.1 | Hypothetical protein; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (202 aa) |
| | AII51421.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (326 aa) |
| | AII51422.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (193 aa) |
| | AII51423.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (156 aa) |
| | AII51424.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (316 aa) |
| | cysS | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-I aminoacyl-tRNA synthetase family. (515 aa) |
| | rimP | Hypothetical protein; Required for maturation of 30S ribosomal subunits. Belongs to the RimP family. (156 aa) |
| | nusA | Transcription elongation factor NusA; Participates in both transcription termination and antitermination. (431 aa) |
| | infB | Hypothetical protein; One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily. (795 aa) |
| | gatA | Hypothetical protein; Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu- tRNA(Gln). (454 aa) |
| | AII51525.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (535 aa) |
| | era | Hypothetical protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. (321 aa) |
| | AII51564.1 | Hypothetical protein; Responsible for synthesis of pseudouridine from uracil. Belongs to the pseudouridine synthase RluA family. (364 aa) |
| | nnrD | Hypothetical protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epi [...] (504 aa) |
| | ppa | Hypothetical protein; Catalyzes the hydrolysis of inorganic pyrophosphate (PPi) forming two phosphate ions. (184 aa) |
| | atpG | Hypothetical protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex. (296 aa) |
| | atpA | F0F1 ATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. (527 aa) |
| | atpH | Hypothetical protein; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (173 aa) |
| | atpF | Hypothetical protein; Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0); Belongs to the ATPase B chain family. (164 aa) |
| | atpE | ATP synthase F0 subunit C; F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. (85 aa) |
| | atpB | Hypothetical protein; Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane. Belongs to the ATPase A chain family. (316 aa) |
| | AII51673.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (614 aa) |
| | AII51694.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1154 aa) |
| | AII51716.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (135 aa) |
| | AII51772.1 | Heme ABC transporter ATP-binding protein; ChvD; in Agrobacterium tumefaciens, mutations in both Walker boxes were found to affect virulence; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (555 aa) |
| | asnS | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (467 aa) |
| | proS | prolyl-tRNA synthetase; Catalyzes the attachment of proline to tRNA(Pro) in a two- step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). (491 aa) |
| | AII51839.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (285 aa) |
| | AII51867.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (107 aa) |
| | gltX | Hypothetical protein; Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu); Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily. (512 aa) |
| | rnr | Hypothetical protein; 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. (832 aa) |
| | ileS | Hypothetical protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily. (1162 aa) |
| | glyQS | glycyl-tRNA synthetease; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. (505 aa) |
| | gidA | tRNA uridine 5-carboxymethylaminomethyl modification protein; NAD-binding protein involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA-cmnm(5)s(2)U34; Belongs to the MnmG family. (621 aa) |
| | rbfA | Hypothetical protein; One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA. (145 aa) |
| | AII52053.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1044 aa) |
| | prfA | Hypothetical protein; Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA. (367 aa) |
| | AII52082.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (304 aa) |
| | rplU | Hypothetical protein; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. (101 aa) |
| | rpmA | 50S ribosomal protein L27; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bL27 family. (94 aa) |
| | rpmB | 50S ribosomal protein L28; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bL28 family. (73 aa) |
| | rpmG | 50S ribosomal protein L33; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bL33 family. (60 aa) |
| | ftsY | Cell division protein FtsY; Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC). (325 aa) |
| | pheS | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. (345 aa) |
| | AII52403.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (159 aa) |
| | AII52429.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (175 aa) |
| | AII52476.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DEAD box helicase family. (475 aa) |
| | rpmH | 50S ribosomal protein L34; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bL34 family. (52 aa) |
| | AII52495.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (99 aa) |
| | xerC-2 | Hypothetical protein; Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The XerC- XerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell division. It also contributes to the segregational stability of plasmids. (295 aa) |
| | rpsU | 30S ribosomal protein S21; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bS21 family. (65 aa) |
| | frr | Ribosome recycling factor; Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another; Belongs to the RRF family. (187 aa) |
| | pyrH | Uridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (261 aa) |
| | tuf | Elongation factor Tu; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (395 aa) |
| | secE | Hypothetical protein; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation. (64 aa) |
| | nusG | Hypothetical protein; Participates in transcription elongation, termination and antitermination. (188 aa) |
| | rplK | 50S ribosomal protein L11; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. (147 aa) |
| | rplA | 50S ribosomal protein L1; Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release. (231 aa) |
| | rplJ | Hypothetical protein; Forms part of the ribosomal stalk, playing a central role in the interaction of the ribosome with GTP-bound translation factors. Belongs to the universal ribosomal protein uL10 family. (184 aa) |
| | rplL | 50S ribosomal protein L7; Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation; Belongs to the bacterial ribosomal protein bL12 family. (125 aa) |
| | rpoB | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1300 aa) |
| | rpoC | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (1450 aa) |
| | AII52561.1 | Hypothetical protein; Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit. (104 aa) |
| | rpsG | 30S ribosomal protein S7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA; Belongs to the universal ribosomal protein uS7 family. (155 aa) |
| | fusA | Elongation factor G; Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily. (699 aa) |
| | rpsJ | 30S ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family. (101 aa) |
| | rplC | 50S ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family. (206 aa) |
| | rplD | Hypothetical protein; Forms part of the polypeptide exit tunnel. (212 aa) |
| | rplW | Hypothetical protein; One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome; Belongs to the universal ribosomal protein uL23 family. (95 aa) |
| | AII52568.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (239 aa) |
| | rpsS | 30S ribosomal protein S19; Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA. (71 aa) |
| | rplV | Hypothetical protein; The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome. (160 aa) |
| | rpsC | Hypothetical protein; Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation; Belongs to the universal ribosomal protein uS3 family. (289 aa) |
| | rplP | 50S ribosomal protein L16; Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs; Belongs to the universal ribosomal protein uL16 family. (141 aa) |
| | rpmC | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the universal ribosomal protein uL29 family. (70 aa) |
| | rpsQ | Hypothetical protein; One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA. (97 aa) |
| | rplN | 50S ribosomal protein L14; Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome; Belongs to the universal ribosomal protein uL14 family. (122 aa) |
| | rplX | Hypothetical protein; One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit. (74 aa) |
| | rplE | 50S ribosomal protein L5; This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs. (185 aa) |
| | rpsN | 30S ribosomal protein S14; Binds 16S rRNA, required for the assembly of 30S particles and may also be responsible for determining the conformation of the 16S rRNA at the A site; Belongs to the universal ribosomal protein uS14 family. (89 aa) |
| | rpsH | 30S ribosomal protein S8; One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit; Belongs to the universal ribosomal protein uS8 family. (132 aa) |
| | rplF | 50S ribosomal protein L6; This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center; Belongs to the universal ribosomal protein uL6 family. (184 aa) |
| | rpsE | Hypothetical protein; Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body. Belongs to the universal ribosomal protein uS5 family. (201 aa) |
| | rpmD | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (59 aa) |
| | AII52583.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the universal ribosomal protein uL15 family. (93 aa) |
| | secY | Preprotein translocase subunit SecY; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently. (439 aa) |
| | map | Hypothetical protein; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. (256 aa) |
| | infA | Translation initiation factor IF-1; One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex. (72 aa) |
| | rpmJ | 50S ribosomal protein L36; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bL36 family. (38 aa) |
| | rpsM | 30S ribosomal protein S13; Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites. Belongs to the universal ribosomal protein uS13 family. (125 aa) |
| | rpsK | 30S ribosomal protein S11; Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine- Dalgarno cleft in the 70S ribosome; Belongs to the universal ribosomal protein uS11 family. (130 aa) |
| | AII52590.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the universal ribosomal protein uS4 family. (133 aa) |
| | rpoA | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. (322 aa) |
| | rplQ | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (196 aa) |
| | AII52602.1 | Heat shock protein Hsp70; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the heat shock protein 70 family. (620 aa) |
| | secA | Hypothetical protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. Has a central role in coupling the hydrolysis of ATP to the transfer of proteins into and across the cell membrane, serving as an ATP-driven molecular motor driving the stepwise translocation of polypeptide chains across the membrane. (1135 aa) |
| | AII52624.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the small heat shock protein (HSP20) family. (147 aa) |
| | tsf | Hypothetical protein; Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF- Tu.GTP complex up to the GTP hydrolysis stage on the ribosome. Belongs to the EF-Ts family. (270 aa) |
| | rpsB | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the universal ribosomal protein uS2 family. (255 aa) |
| | rpsI | 30S ribosomal protein S9; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the universal ribosomal protein uS9 family. (128 aa) |
| | rplM | Hypothetical protein; This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly. (150 aa) |
| | AII52662.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (237 aa) |
| | AII52682.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (389 aa) |
| | AII52684.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (407 aa) |
| | secF | Hypothetical protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA; Belongs to the SecD/SecF family. SecD subfamily. (1006 aa) |
| | rpmE2 | 50S ribosomal protein L31; RpmE2; there appears to be two types of ribosomal proteins L31 in bacterial genomes; some contain a CxxC motif while others do not; Bacillus subtilis has both types; the proteins in this cluster do not have the CXXC motif; RpmE is found in exponentially growing Bacilli while YtiA was found after exponential growth; expression of ytiA is controlled by a zinc-specific transcriptional repressor; RpmE contains one zinc ion and a CxxC motif is responsible for this binding; forms an RNP particle along with proteins L5, L18, and L25 and 5S rRNA; found crosslinked to [...] (81 aa) |
| | rsfS | Hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation. (129 aa) |
| | AII52804.1 | Thioredoxin; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the thioredoxin family. (109 aa) |
| | AII52830.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (424 aa) |
| | rho | Hypothetical protein; Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA- dependent ATPase activity, and release of the mRNA from the DNA template. (748 aa) |
| | AII52848.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (192 aa) |
| | rplS | 50S ribosomal protein L19; This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site. (123 aa) |
| | trmD | tRNA (guanine-N1)-methyltransferase; Specifically methylates guanosine-37 in various tRNAs. Belongs to the RNA methyltransferase TrmD family. (225 aa) |
| | rimM | Hypothetical protein; An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes; Belongs to the RimM family. (193 aa) |
| | rpsP | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bS16 family. (180 aa) |
| | AII52856.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (235 aa) |
| | AII52881.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (180 aa) |
| | lon | Lon protease; ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short- lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner. (819 aa) |
| | hslU | ATP-dependent protease; ATPase subunit of a proteasome-like degradation complex; this subunit has chaperone activity. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolyzed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. (469 aa) |
| | prfB | Hypothetical protein; Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA. (301 aa) |
| | gatC | glutamyl-tRNA amidotransferase subunit C; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatC family. (95 aa) |
| | AII52931.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (192 aa) |
| | AII52946.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (389 aa) |
| | rplI | 50S ribosomal protein L9; Binds to the 23S rRNA. (147 aa) |
| | rpsR | 30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family. (83 aa) |
| | rpsF | Hypothetical protein; Binds together with S18 to 16S ribosomal RNA. (124 aa) |
| | smpB | Hypothetical protein; Required for rescue of stalled ribosomes mediated by trans- translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to [...] (157 aa) |
| | AII53016.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (695 aa) |
| | yidC | Hypothetical protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. (622 aa) |
| | AII53109.1 | ATPase AAA; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (389 aa) |
| | clpP | ATP-dependent Clp protease ClpP; Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins. Belongs to the peptidase S14 family. (236 aa) |
| | AII53111.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (441 aa) |
| | argS | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (667 aa) |
| | AII53149.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DEAD box helicase family. (577 aa) |
| | hslV | Peptidase; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery. (178 aa) |
| | AII53228.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (545 aa) |
| | ychF | GTP-binding protein YchF; ATPase that binds to both the 70S ribosome and the 50S ribosomal subunit in a nucleotide-independent manner. (365 aa) |
| | AII53299.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (639 aa) |
| | AII53322.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (93 aa) |
| | AII53519.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DEAD box helicase family. (460 aa) |
| | AII53552.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DEAD box helicase family. (638 aa) |
| | AII53576.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DEAD box helicase family. (483 aa) |
| | groEL | Molecular chaperone GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions. (546 aa) |
| | groS | Molecular chaperone GroES; Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter. (96 aa) |
| | AII53619.1 | Hypothetical protein; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. (133 aa) |
| | AII53626.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (489 aa) |
| | leuS | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-I aminoacyl-tRNA synthetase family. (925 aa) |
| | gatB | Hypothetical protein; Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl- tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp- tRNA(Asn) or phospho-Glu-tRNA(Gln); Belongs to the GatB/GatE family. GatB subfamily. (485 aa) |
| | AII53768.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (248 aa) |
| | gyrA | DNA gyrase subunit A; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. (853 aa) |
| | tyrS | Hypothetical protein; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 1 subfamily. (432 aa) |
| | AII53928.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (327 aa) |
| | pnp | Hypothetical protein; Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'- direction. (719 aa) |
| | rpsO | 30S ribosomal protein S15; Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome. (91 aa) |
| | AII53939.1 | Inorganic diphosphatase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (41 aa) |
| | rpmI | 50S ribosomal protein L35; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bL35 family. (64 aa) |
| | AII53942.1 | Hypothetical protein; IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins. (160 aa) |
| | thrS | threonyl-tRNA synthetase; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). (648 aa) |
| | AII53946.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (987 aa) |
| | AII53947.1 | DNA topoisomerase IV subunit B; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (638 aa) |
| | mnmE | Hypothetical protein; Exhibits a very high intrinsic GTPase hydrolysis rate. Involved in the addition of a carboxymethylaminomethyl (cmnm) group at the wobble position (U34) of certain tRNAs, forming tRNA- cmnm(5)s(2)U34; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. TrmE GTPase family. (463 aa) |
| | lepA | GTP-binding protein LepA; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. (595 aa) |
| | engB | Hypothetical protein; Necessary for normal cell division and for the maintenance of normal septation; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngB GTPase family. (196 aa) |
| | AII54124.1 | Peptidylprolyl isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (153 aa) |
| | rsmA | Hypothetical protein; Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. (262 aa) |
| | AII54184.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (180 aa) |
| | rpmF | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the bacterial ribosomal protein bL32 family. (75 aa) |
| | efp | Elongation factor P; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. (187 aa) |
| | AII54214.1 | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (628 aa) |
| | hisS | Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (467 aa) |
