STRINGSTRING
guaA guaA AII50443.1 AII50443.1 AII50475.1 AII50475.1 AII50476.1 AII50476.1 AII50480.1 AII50480.1 trpA trpA trpB trpB trpF trpF AII50485.1 AII50485.1 trpD trpD AII50487.1 AII50487.1 AII50488.1 AII50488.1 AII50511.1 AII50511.1 AII50522.1 AII50522.1 aroQ aroQ AII50534.1 AII50534.1 AII50566.1 AII50566.1 AII50594.1 AII50594.1 AII50600.1 AII50600.1 AII50641.1 AII50641.1 lysA lysA AII50680.1 AII50680.1 AII50759.1 AII50759.1 AII50870.1 AII50870.1 AII50910.1 AII50910.1 AII50911.1 AII50911.1 carA carA purK purK purE purE pyrC pyrC pyrB pyrB AII50918.1 AII50918.1 argC argC AII50921.1 AII50921.1 AII50922.1 AII50922.1 argB argB AII50924.1 AII50924.1 AII50925.1 AII50925.1 AII50945.1 AII50945.1 AII50946.1 AII50946.1 AII50951.1 AII50951.1 aroA aroA AII51053.1 AII51053.1 AII51057.1 AII51057.1 AII51087.1 AII51087.1 AII51088.1 AII51088.1 AII51102.1 AII51102.1 adk adk AII51148.1 AII51148.1 AII51152.1 AII51152.1 AII50336.1 AII50336.1 nadE nadE AII51215.1 AII51215.1 AII51216.1 AII51216.1 AII51247.1 AII51247.1 AII51298.1 AII51298.1 AII51333.1 AII51333.1 ndk ndk tdk tdk purH purH AII51448.1 AII51448.1 asd asd AII51483.1 AII51483.1 metXA metXA AII51485.1 AII51485.1 dut dut AII51540.1 AII51540.1 AII51555.1 AII51555.1 nadK nadK AII51575.1 AII51575.1 pdxJ pdxJ AII51637.1 AII51637.1 AII51738.1 AII51738.1 AII51840.1 AII51840.1 AII51841.1 AII51841.1 AII51871.1 AII51871.1 panD panD panC panC coaX coaX ribH ribH glyA glyA AII52006.1 AII52006.1 AII52007.1 AII52007.1 AII52008.1 AII52008.1 AII52009.1 AII52009.1 AII52026.1 AII52026.1 AII52029.1 AII52029.1 AII52064.1 AII52064.1 thrB thrB AII52066.1 AII52066.1 AII52074.1 AII52074.1 AII50347.1 AII50347.1 AII52115.1 AII52115.1 AII52133.1 AII52133.1 AII52135.1 AII52135.1 AII52195.1 AII52195.1 AII52229.1 AII52229.1 AII52271.1 AII52271.1 aroK aroK gcvP gcvP AII52360.1 AII52360.1 AII52361.1 AII52361.1 pyrE pyrE purL purL AII52365.1 AII52365.1 purC purC AII52368.1 AII52368.1 purN purN purF purF AII52371.1 AII52371.1 AII52375.1 AII52375.1 AII52398.1 AII52398.1 gcvH gcvH pyrD pyrD AII52474.1 AII52474.1 AII52477.1 AII52477.1 metK metK AII52511.1 AII52511.1 ahcY ahcY gmk gmk nadD nadD AII52550.1 AII52550.1 dapF dapF guaB guaB aroC aroC AII52715.1 AII52715.1 AII52716.1 AII52716.1 AII52778.1 AII52778.1 AII52799.1 AII52799.1 folE folE AII52846.1 AII52846.1 panB panB AII52874.1 AII52874.1 AII52899.1 AII52899.1 AII52900.1 AII52900.1 gcvT gcvT AII53027.1 AII53027.1 pyrG pyrG AII53039.1 AII53039.1 AII53059.1 AII53059.1 AII53107.1 AII53107.1 purA purA AII53123.1 AII53123.1 AII53132.1 AII53132.1 AII53217.1 AII53217.1 coaD coaD AII53273.1 AII53273.1 AII53294.1 AII53294.1 AII53296.1 AII53296.1 AII53297.1 AII53297.1 AII53298.1 AII53298.1 AII53331.1 AII53331.1 fmt fmt asnA asnA purU purU AII53428.1 AII53428.1 AII53459.1 AII53459.1 AII53569.1 AII53569.1 AII53625.1 AII53625.1 AII53691.1 AII53691.1 thyA thyA AII53726.1 AII53726.1 AII53754.1 AII53754.1 AII53786.1 AII53786.1 pdxH pdxH hisI hisI AII53875.1 AII53875.1 AII53876.1 AII53876.1 hisA hisA hisH hisH hisB hisB AII53880.1 AII53880.1 hisC hisC hisD hisD hisG hisG AII53895.1 AII53895.1 AII53898.1 AII53898.1 AII53977.1 AII53977.1 queE queE folD folD dapA dapA surE surE ribBA ribBA AII54080.1 AII54080.1 AII54107.1 AII54107.1 AII54117.1 AII54117.1 AII54135.1 AII54135.1 AII54178.1 AII54178.1 AII54181.1 AII54181.1 AII54182.1 AII54182.1 AII54353.1 AII54353.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
guaAHypothetical protein; Catalyzes the synthesis of GMP from XMP. (510 aa)
AII50443.1Deoxycytidine triphosphate deaminase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (178 aa)
AII50475.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (252 aa)
AII50476.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (244 aa)
AII50480.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (337 aa)
trpAHypothetical protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. (259 aa)
trpBTryptophan synthase subunit beta; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. (398 aa)
trpFHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TrpF family. (200 aa)
AII50485.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the TrpC family. (270 aa)
trpDHypothetical protein; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). (330 aa)
AII50487.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (188 aa)
AII50488.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (471 aa)
AII50511.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the CinA family. (418 aa)
AII50522.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (290 aa)
aroQHypothetical protein; Catalyzes a trans-dehydration via an enolate intermediate. Belongs to the type-II 3-dehydroquinase family. (148 aa)
AII50534.1Hypothetical protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine. (354 aa)
AII50566.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (349 aa)
AII50594.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (204 aa)
AII50600.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (319 aa)
AII50641.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartokinase family. (441 aa)
lysAHypothetical protein; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine. (382 aa)
AII50680.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (267 aa)
AII50759.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (159 aa)
AII50870.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (470 aa)
AII50910.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. (314 aa)
AII50911.1Carbamoyl phosphate synthase large subunit; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1076 aa)
carAHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the CarA family. (360 aa)
purKHypothetical protein; Catalyzes the ATP-dependent conversion of 5-aminoimidazole ribonucleotide (AIR) and HCO(3)(-) to N5-carboxyaminoimidazole ribonucleotide (N5-CAIR). (415 aa)
purEN5-carboxyaminoimidazole ribonucleotide mutase; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). (172 aa)
pyrCHypothetical protein; Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate; Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily. (432 aa)
pyrBHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. (327 aa)
AII50918.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (387 aa)
argCHypothetical protein; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. (326 aa)
AII50921.1Argininosuccinate synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the argininosuccinate synthase family. Type 1 subfamily. (395 aa)
AII50922.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (189 aa)
argBHypothetical protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (260 aa)
AII50924.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (355 aa)
AII50925.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (432 aa)
AII50945.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (95 aa)
AII50946.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (65 aa)
AII50951.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (406 aa)
aroAHypothetical protein; Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate. (424 aa)
AII51053.1Hypothetical protein; Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ). (346 aa)
AII51057.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (364 aa)
AII51087.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (216 aa)
AII51088.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (185 aa)
AII51102.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (176 aa)
adkHypothetical protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (207 aa)
AII51148.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (636 aa)
AII51152.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (279 aa)
AII50336.1Cysteine synthase; Derived by automated computational analysis using gene prediction method: Protein Homology; Belongs to the cysteine synthase/cystathionine beta- synthase family. (306 aa)
nadEHypothetical protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (644 aa)
AII51215.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (379 aa)
AII51216.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (287 aa)
AII51247.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (401 aa)
AII51298.1Cystathionine beta-synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (325 aa)
AII51333.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (399 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (207 aa)
purHIMP cyclohydrolase; Derived by automated computational analysis using gene prediction method: Protein Homology. (511 aa)
AII51448.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (278 aa)
asdAspartate-semialdehyde dehydrogenase; Catalyzes the NADPH-dependent formation of L-aspartate- semialdehyde (L-ASA) by the reductive dephosphorylation of L-aspartyl- 4-phosphate; Belongs to the aspartate-semialdehyde dehydrogenase family. (332 aa)
AII51483.1O-acetylhomoserine aminocarboxypropyltransferase; Catalyzes the formation of L-methionine and acetate from O-acetyl-L-homoserine and methanethiol; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (460 aa)
metXAHypothetical protein; Transfers an acetyl group from acetyl-CoA to L-homoserine, forming acetyl-L-homoserine. (349 aa)
AII51485.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (439 aa)
dutDeoxyuridine 5'-triphosphate nucleotidohydrolase; This enzyme is involved in nucleotide metabolism: it produces dUMP, the immediate precursor of thymidine nucleotides and it decreases the intracellular concentration of dUTP so that uracil cannot be incorporated into DNA; Belongs to the dUTPase family. (144 aa)
AII51540.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the arginase family. (382 aa)
AII51555.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (279 aa)
nadKHypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (297 aa)
AII51575.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (205 aa)
pdxJHypothetical protein; Catalyzes the complicated ring closure reaction between the two acyclic compounds 1-deoxy-D-xylulose-5-phosphate (DXP) and 3-amino- 2-oxopropyl phosphate (1-amino-acetone-3-phosphate or AAP) to form pyridoxine 5'-phosphate (PNP) and inorganic phosphate. (237 aa)
AII51637.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the iron-sulfur dependent L-serine dehydratase family. (300 aa)
AII51738.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (829 aa)
AII51840.1Hypothetical protein; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. (346 aa)
AII51841.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (160 aa)
AII51871.1Hypothetical protein; Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons. (394 aa)
panDAspartate decarboxylase; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine. (115 aa)
panCHypothetical protein; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family. (281 aa)
coaXHypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (247 aa)
ribH6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. (158 aa)
glyASerine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. (430 aa)
AII52006.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (309 aa)
AII52007.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (402 aa)
AII52008.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (281 aa)
AII52009.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (356 aa)
AII52026.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (82 aa)
AII52029.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the inositol monophosphatase superfamily. (264 aa)
AII52064.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (433 aa)
thrBHypothetical protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (307 aa)
AII52066.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (814 aa)
AII52074.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the NadC/ModD family. (286 aa)
AII50347.1Ribonucleotide reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (793 aa)
AII52115.1Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides; Belongs to the ribonucleoside diphosphate reductase small chain family. (320 aa)
AII52133.1Hypothetical protein; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate. (1241 aa)
AII52135.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the methylenetetrahydrofolate reductase family. (318 aa)
AII52195.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (402 aa)
AII52229.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (417 aa)
AII52271.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (293 aa)
aroKHypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (180 aa)
gcvPGlycine dehydrogenase; The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. (974 aa)
AII52360.1Hypothetical protein; Catalyzes the conversion of dihydroorotate to orotate. (274 aa)
AII52361.1Hypothetical protein; Catalyzes the decarboxylation of orotidine 5'-monophosphate (OMP) to uridine 5'-monophosphate (UMP). Belongs to the OMP decarboxylase family. Type 2 subfamily. (253 aa)
pyrEHypothetical protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP). (205 aa)
purLHypothetical protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist in the transfer of the am [...] (1008 aa)
AII52365.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (352 aa)
purCHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the SAICAR synthetase family. (307 aa)
AII52368.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (409 aa)
purNHypothetical protein; Catalyzes the transfer of a formyl group from 10- formyltetrahydrofolate to 5-phospho-ribosyl-glycinamide (GAR), producing 5-phospho-ribosyl-N-formylglycinamide (FGAR) and tetrahydrofolate. (237 aa)
purFHypothetical protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine. (484 aa)
AII52371.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (390 aa)
AII52375.1Hypothetical protein; Catalyzes the first step in the biosynthesis of NAD from nicotinic acid, the ATP-dependent synthesis of beta-nicotinate D- ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate. Belongs to the NAPRTase family. (495 aa)
AII52398.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (386 aa)
gcvHGlycine cleavage system protein H; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. (126 aa)
pyrDHypothetical protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. (343 aa)
AII52474.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (230 aa)
AII52477.1Sugar kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (310 aa)
metKHypothetical protein; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. (420 aa)
AII52511.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (247 aa)
ahcYS-adenosyl-L-homocysteine hydrolase; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine. (439 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (194 aa)
nadDHypothetical protein; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). (199 aa)
AII52550.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (799 aa)
dapFHypothetical protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. (267 aa)
guaBInosine 5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. (490 aa)
aroCHypothetical protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. (358 aa)
AII52715.1Uridine kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the uridine kinase family. (208 aa)
AII52716.1Hypothetical protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. (197 aa)
AII52778.1Cystathionine beta-lyase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (379 aa)
AII52799.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (384 aa)
folEGTP cyclohydrolase I; Involved in the first step of tetrahydrofolate biosynthesis; catalyzes the formation of formate and 2-amino-4-hydroxy-6-(erythro-1,2, 3-trihydroxypropyl)dihydropteridine triphosphate from GTP and water; forms a homopolymer; Derived by automated computational analysis using gene prediction method: Protein Homology. (224 aa)
AII52846.16-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (135 aa)
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (271 aa)
AII52874.1Hypothetical protein; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (124 aa)
AII52899.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (254 aa)
AII52900.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (291 aa)
gcvTHypothetical protein; The glycine cleavage system catalyzes the degradation of glycine. (368 aa)
AII53027.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the DapB family. (239 aa)
pyrGCTP synthetase; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. (526 aa)
AII53039.1Hypothetical protein; Catalyzes the reversible oxidation of 3-phospho-D-glycerate to 3-phosphonooxypyruvate, the first step of the phosphorylated L- serine biosynthesis pathway. Also catalyzes the reversible oxidation of 2-hydroxyglutarate to 2-oxoglutarate; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (634 aa)
AII53059.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (581 aa)
AII53107.16-pyruvoyl tetrahydrobiopterin synthase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (138 aa)
purAHypothetical protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family. (423 aa)
AII53123.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. (454 aa)
AII53132.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the arginase family. (324 aa)
AII53217.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (436 aa)
coaDPhosphopantetheine adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. (157 aa)
AII53273.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (367 aa)
AII53294.14-hydroxyphenylpyruvate dioxygenase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (374 aa)
AII53296.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (114 aa)
AII53297.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (206 aa)
AII53298.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (277 aa)
AII53331.1Hypothetical protein; Key enzyme in folate metabolism. Catalyzes an essential reaction for de novo glycine and purine synthesis, and for DNA precursor synthesis. (161 aa)
fmtHypothetical protein; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family. (317 aa)
asnAHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (330 aa)
purUHypothetical protein; Catalyzes the hydrolysis of 10-formyltetrahydrofolate (formyl-FH4) to formate and tetrahydrofolate (FH4). (276 aa)
AII53428.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (397 aa)
AII53459.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (823 aa)
AII53569.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (323 aa)
AII53625.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (424 aa)
AII53691.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (202 aa)
thyAThymidylate synthase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. (264 aa)
AII53726.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (272 aa)
AII53754.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (196 aa)
AII53786.1Serine dehydratase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the iron-sulfur dependent L-serine dehydratase family. (226 aa)
pdxHHypothetical protein; Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP). (216 aa)
hisIHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; In the N-terminal section; belongs to the PRA-CH family. (212 aa)
AII53875.1Hypothetical protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit. (241 aa)
AII53876.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (42 aa)
hisAHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (238 aa)
hisHHypothetical protein; IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisH subunit catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the synthesis of IGP and AICAR. The resulting ammonia molecule is channeled to the active site of HisF. (196 aa)
hisBHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; In the C-terminal section; belongs to the imidazoleglycerol-phosphate dehydratase family. (370 aa)
AII53880.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (90 aa)
hisCHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. (350 aa)
hisDHypothetical protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. (433 aa)
hisGHypothetical protein; Catalyzes the condensation of ATP and 5-phosphoribose 1- diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity. Belongs to the ATP phosphoribosyltransferase family. Long subfamily. (283 aa)
AII53895.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (209 aa)
AII53898.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the folylpolyglutamate synthase family. (433 aa)
AII53977.12,3,4,5-tetrahydropyridine-2,6-carboxylate N-succinyltransferase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the transferase hexapeptide repeat family. (274 aa)
queEHypothetical protein; Catalyzes the complex heterocyclic radical-mediated conversion of 6-carboxy-5,6,7,8-tetrahydropterin (CPH4) to 7-carboxy-7- deazaguanine (CDG), a step common to the biosynthetic pathways of all 7-deazapurine-containing compounds. (210 aa)
folDHypothetical protein; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. (303 aa)
dapAHypothetical protein; Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA). (288 aa)
surEHypothetical protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. (289 aa)
ribBA3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family. (415 aa)
AII54080.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (427 aa)
AII54107.1Hypothetical protein; This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis; Belongs to the cytidine and deoxycytidylate deaminase family. (163 aa)
AII54117.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartokinase family. (426 aa)
AII54135.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (355 aa)
AII54178.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (313 aa)
AII54181.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the peptidase M17 family. (482 aa)
AII54182.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the PdxA family. (350 aa)
AII54353.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (196 aa)
Your Current Organism:
Hymenobacter sp. APR13
NCBI taxonomy Id: 1356852
Other names: H. sp. APR13
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