STRINGSTRING
aroK aroK AII52303.1 AII52303.1 AII52330.1 AII52330.1 AII52353.1 AII52353.1 ppk ppk AII52399.1 AII52399.1 tpiA tpiA AII52477.1 AII52477.1 AII52500.1 AII52500.1 AII52520.1 AII52520.1 gmk gmk pyrH pyrH AII52560.1 AII52560.1 AII52594.1 AII52594.1 eno eno anmK anmK AII52633.1 AII52633.1 AII52663.1 AII52663.1 AII52675.1 AII52675.1 AII52680.1 AII52680.1 AII52715.1 AII52715.1 AII52735.1 AII52735.1 AII52757.1 AII52757.1 AII52783.1 AII52783.1 AII52785.1 AII52785.1 AII52790.1 AII52790.1 AII52840.1 AII52840.1 AII52868.1 AII52868.1 AII52878.1 AII52878.1 AII52935.1 AII52935.1 AII52981.1 AII52981.1 AII53002.1 AII53002.1 AII53170.1 AII53170.1 AII53180.1 AII53180.1 AII53183.1 AII53183.1 AII53259.1 AII53259.1 AII53282.1 AII53282.1 AII53291.1 AII53291.1 thiL thiL AII53381.1 AII53381.1 AII53423.1 AII53423.1 pfkA pfkA AII53481.1 AII53481.1 AII53482.1 AII53482.1 AII53491.1 AII53491.1 AII53492.1 AII53492.1 AII53604.1 AII53604.1 AII53606.1 AII53606.1 lpxK lpxK AII53679.1 AII53679.1 AII53758.1 AII53758.1 AII53832.1 AII53832.1 AII53852.1 AII53852.1 AII53922.1 AII53922.1 AII53964.1 AII53964.1 AII54054.1 AII54054.1 AII54074.1 AII54074.1 AII54075.1 AII54075.1 AII54086.1 AII54086.1 AII54094.1 AII54094.1 AII54117.1 AII54117.1 AII54136.1 AII54136.1 AII54137.1 AII54137.1 AII54202.1 AII54202.1 AII54206.1 AII54206.1 ppk-2 ppk-2 AII54221.1 AII54221.1 AII54222.1 AII54222.1 AII54324.1 AII54324.1 AII54340.1 AII54340.1 AII54358.1 AII54358.1 AII54369.1 AII54369.1 AII54379.1 AII54379.1 AII54413.1 AII54413.1 AII53740.1 AII53740.1 AII50432.1 AII50432.1 AII50472.1 AII50472.1 AII50494.1 AII50494.1 AII50641.1 AII50641.1 AII50653.1 AII50653.1 AII50656.1 AII50656.1 AII50699.1 AII50699.1 AII50717.1 AII50717.1 AII50718.1 AII50718.1 AII50742.1 AII50742.1 AII50750.1 AII50750.1 AII50759.1 AII50759.1 AII50865.1 AII50865.1 AII50883.1 AII50883.1 argB argB ackA ackA AII50950.1 AII50950.1 AII50997.1 AII50997.1 AII51024.1 AII51024.1 adk adk AII51178.1 AII51178.1 ispE ispE AII51219.1 AII51219.1 AII51234.1 AII51234.1 AII51287.1 AII51287.1 cmk cmk AII51366.1 AII51366.1 AII51378.1 AII51378.1 AII51405.1 AII51405.1 AII51408.1 AII51408.1 ndk ndk tdk tdk AII51477.1 AII51477.1 AII51508.1 AII51508.1 nadK nadK selD selD AII51584.1 AII51584.1 AII51608.1 AII51608.1 AII51610.1 AII51610.1 AII51616.1 AII51616.1 AII51633.1 AII51633.1 AII51634.1 AII51634.1 AII51672.1 AII51672.1 AII51856.1 AII51856.1 coaE coaE AII51876.1 AII51876.1 AII51907.1 AII51907.1 AII51908.1 AII51908.1 AII51916.1 AII51916.1 AII51930.1 AII51930.1 coaX coaX AII51973.1 AII51973.1 AII51995.1 AII51995.1 AII52015.1 AII52015.1 AII52048.1 AII52048.1 AII52062.1 AII52062.1 thrB thrB AII52066.1 AII52066.1 gpmI gpmI AII52089.1 AII52089.1 AII52127.1 AII52127.1 AII52164.1 AII52164.1 AII52169.1 AII52169.1 AII52188.1 AII52188.1 AII52202.1 AII52202.1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aroKHypothetical protein; Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate; Belongs to the shikimate kinase family. (180 aa)
AII52303.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (649 aa)
AII52330.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (351 aa)
AII52353.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1189 aa)
ppkHypothetical protein; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (706 aa)
AII52399.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (238 aa)
tpiAHypothetical protein; Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D- glyceraldehyde-3-phosphate (G3P); Belongs to the triosephosphate isomerase family. (254 aa)
AII52477.1Sugar kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (310 aa)
AII52500.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (822 aa)
AII52520.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1242 aa)
gmkGuanylate kinase; Essential for recycling GMP and indirectly, cGMP. (194 aa)
pyrHUridylate kinase; Catalyzes the reversible phosphorylation of UMP to UDP. (261 aa)
AII52560.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (114 aa)
AII52594.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (341 aa)
enoEnolase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family. (423 aa)
anmKHypothetical protein; Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived from its own cell wall murein, and thus plays a role in cell wall recycling; Belongs to the anhydro-N-acetylmuramic acid kinase family. (405 aa)
AII52633.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1108 aa)
AII52663.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (367 aa)
AII52675.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (138 aa)
AII52680.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (279 aa)
AII52715.1Uridine kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the uridine kinase family. (208 aa)
AII52735.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1193 aa)
AII52757.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (860 aa)
AII52783.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (847 aa)
AII52785.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (402 aa)
AII52790.1Fructose-bisphosphate aldolase; Catalyzes the formation of glycerone phosphate and D-glyceraldehyde 3-phosphate from D-fructose 1,6-bisphosphate; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (350 aa)
AII52840.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (536 aa)
AII52868.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (291 aa)
AII52878.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (325 aa)
AII52935.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (513 aa)
AII52981.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1249 aa)
AII53002.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the ribF family. (315 aa)
AII53170.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (434 aa)
AII53180.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (371 aa)
AII53183.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (348 aa)
AII53259.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (739 aa)
AII53282.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (563 aa)
AII53291.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (682 aa)
thiLHypothetical protein; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family. (344 aa)
AII53381.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (252 aa)
AII53423.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1362 aa)
pfkA6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis. (324 aa)
AII53481.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (971 aa)
AII53482.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (659 aa)
AII53491.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (289 aa)
AII53492.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (465 aa)
AII53604.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (414 aa)
AII53606.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (773 aa)
lpxKHypothetical protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA). (354 aa)
AII53679.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (385 aa)
AII53758.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1024 aa)
AII53832.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (650 aa)
AII53852.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (190 aa)
AII53922.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (538 aa)
AII53964.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (291 aa)
AII54054.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (454 aa)
AII54074.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (369 aa)
AII54075.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (390 aa)
AII54086.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (916 aa)
AII54094.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (679 aa)
AII54117.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartokinase family. (426 aa)
AII54136.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (200 aa)
AII54137.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (707 aa)
AII54202.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (543 aa)
AII54206.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1473 aa)
ppk-2Hypothetical protein; Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP). Belongs to the polyphosphate kinase 1 (PPK1) family. (768 aa)
AII54221.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (484 aa)
AII54222.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (432 aa)
AII54324.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (494 aa)
AII54340.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (539 aa)
AII54358.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (392 aa)
AII54369.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (408 aa)
AII54379.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (458 aa)
AII54413.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (371 aa)
AII53740.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (460 aa)
AII50432.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (699 aa)
AII50472.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (438 aa)
AII50494.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (281 aa)
AII50641.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the aspartokinase family. (441 aa)
AII50653.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (466 aa)
AII50656.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (797 aa)
AII50699.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (261 aa)
AII50717.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (942 aa)
AII50718.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (275 aa)
AII50742.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (365 aa)
AII50750.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (286 aa)
AII50759.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (159 aa)
AII50865.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+; Belongs to the GHMP kinase family. GalK subfamily. (358 aa)
AII50883.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (608 aa)
argBHypothetical protein; Catalyzes the ATP-dependent phosphorylation of N-acetyl-L- glutamate; Belongs to the acetylglutamate kinase family. ArgB subfamily. (260 aa)
ackAHypothetical protein; Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction; Belongs to the acetokinase family. (397 aa)
AII50950.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (337 aa)
AII50997.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (207 aa)
AII51024.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (271 aa)
adkHypothetical protein; Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism; Belongs to the adenylate kinase family. (207 aa)
AII51178.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (525 aa)
ispEHypothetical protein; Catalyzes the phosphorylation of the position 2 hydroxy group of 4-diphosphocytidyl-2C-methyl-D-erythritol. (273 aa)
AII51219.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (309 aa)
AII51234.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (510 aa)
AII51287.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (96 aa)
cmkHypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (242 aa)
AII51366.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (367 aa)
AII51378.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (182 aa)
AII51405.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1018 aa)
AII51408.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (320 aa)
ndkNucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. (139 aa)
tdkThymidine kinase; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (207 aa)
AII51477.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1159 aa)
AII51508.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (303 aa)
nadKHypothetical protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (297 aa)
selDHypothetical protein; Synthesizes selenophosphate from selenide and ATP. (352 aa)
AII51584.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (608 aa)
AII51608.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (287 aa)
AII51610.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (919 aa)
AII51616.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1019 aa)
AII51633.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (109 aa)
AII51634.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (190 aa)
AII51672.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (321 aa)
AII51856.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (393 aa)
coaEHypothetical protein; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. (182 aa)
AII51876.1Fructose-bisphosphate aldolase; Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis; Belongs to the class II fructose-bisphosphate aldolase family. (360 aa)
AII51907.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (393 aa)
AII51908.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (588 aa)
AII51916.1Hypothetical protein; Catalyzes the ADP transfer from ATP to D-glycero-beta-D- manno-heptose 1-phosphate, yielding ADP-D-glycero-beta-D-manno-heptose. (159 aa)
AII51930.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (144 aa)
coaXHypothetical protein; Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis. (247 aa)
AII51973.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (150 aa)
AII51995.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (332 aa)
AII52015.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (461 aa)
AII52048.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (119 aa)
AII52062.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (250 aa)
thrBHypothetical protein; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily. (307 aa)
AII52066.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (814 aa)
gpmIHypothetical protein; Catalyzes the interconversion of 2-phosphoglycerate and 3- phosphoglycerate. (515 aa)
AII52089.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (258 aa)
AII52127.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (716 aa)
AII52164.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (1404 aa)
AII52169.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (468 aa)
AII52188.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (338 aa)
AII52202.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: GeneMarkS+. (129 aa)
Your Current Organism:
Hymenobacter sp. APR13
NCBI taxonomy Id: 1356852
Other names: H. sp. APR13
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.