(71 nodes) Mixed, incl. Transmembrane receptor protein tyrosine kinase signaling pathway, and Ras subfamily of RAS small GTPases network (Zootermopsis nevadensis)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	L798_04191	Protein lap4. (1249 aa)
	L798_02304	Ras-related protein Rap-2c. (332 aa)
	L798_02525	Ras-like protein 1. (191 aa)
	L798_02242	Putative Ras GTPase-activating protein. (1075 aa)
	L798_04193	Protein lap4. (329 aa)
	L798_15690	Uncharacterized protein. (543 aa)
	L798_15730	Ras-specific guanine nucleotide-releasing factor 2. (1335 aa)
	L798_14367	Guanylate cyclase. (1254 aa)
	L798_15169	Connector enhancer of kinase suppressor of ras 2. (1871 aa)
	L798_15731	Ras-specific guanine nucleotide-releasing factor 1. (126 aa)
	L798_15428	Ras-related protein M-Ras. (197 aa)
	L798_13452	Growth factor receptor-bound protein 10. (424 aa)
	L798_05820	Tyrosine-protein phosphatase non-receptor type 9. (274 aa)
	L798_03655	Tyrosine-protein kinase. (970 aa)
	L798_13919	Rap guanine nucleotide exchange factor 4. (1012 aa)
	L798_13808	Raf-like protein serine/threonine-protein kinase phl. (675 aa)
	L798_13300	Ras-like protein 3. (157 aa)
	L798_01072	Guanine nucleotide-releasing factor 2. (1282 aa)
	L798_12263	Uncharacterized protein. (549 aa)
	L798_13301	Spaetzle domain-containing protein. (209 aa)
	L798_01361	SH2B adapter protein 2. (563 aa)
	L798_10395	Phosphatidylinositol 3-kinase regulatory subunit gamma. (569 aa)
	L798_01386	Ras-like protein. (156 aa)
	L798_11478	Receptor protein-tyrosine kinase. (1430 aa)
	L798_15638	Cytokine receptor. (1023 aa)
	L798_15019	GTP-binding protein Rit1. (234 aa)
	L798_13674	Protein E(Sev)2B. (211 aa)
	L798_10430	GTP-binding protein Rhes. (259 aa)
	L798_09858	Docking protein 3. (565 aa)
	L798_09878	Receptor protein-tyrosine kinase. (1356 aa)
	L798_11002	E3 ubiquitin-protein ligase CBL-B. (737 aa)
	L798_10727	Uncharacterized protein. (163 aa)
	L798_10097	Receptor-type tyrosine-protein phosphatase R. (521 aa)
	L798_09337	Uncharacterized protein. (287 aa)
	L798_10538	Non-specific serine/threonine protein kinase. (773 aa)
	L798_09226	Uncharacterized protein. (694 aa)
	L798_08104	Receptor protein-tyrosine kinase. (1433 aa)
	L798_09607	Uncharacterized protein. (528 aa)
	L798_13563	Non-specific serine/threonine protein kinase. (922 aa)
	L798_12488	Insulin receptor substrate 1. (1505 aa)
	L798_11905	Uncharacterized protein. (219 aa)
	L798_10187	GTP-binding protein Di-Ras2. (202 aa)
	L798_11827	Ras GTPase-activating protein 3. (848 aa)
	L798_06349	Dual specificity mitogen-activated protein kinase kinase dSOR1; Belongs to the protein kinase superfamily. (425 aa)
	L798_09778	Ras-like protein 2. (199 aa)
	L798_11318	Rap1 GTPase-activating protein 1. (506 aa)
	L798_11209	Protein sprouty. (428 aa)
	L798_10313	Kinase suppressor of Ras 1. (929 aa)
	L798_07400	Serine/threonine-protein kinase SIK2. (770 aa)
	L798_07329	B-cell linker protein. (660 aa)
	L798_09336	CD2-associated protein. (310 aa)
	L798_05178	Protein lap4. (427 aa)
	L798_05121	Cold shock domain-containing protein E1. (938 aa)
	L798_05582	BRCA1-associated protein. (566 aa)
	L798_04219	Rho GTPase-activating protein. (1073 aa)
	L798_03142	Receptor protein-tyrosine kinase. (1365 aa)
	L798_03143	Tyrosine-protein kinase receptor. (1628 aa)
	L798_07970	Ras guanyl-releasing protein 3. (793 aa)
	L798_01715	Tyrosine-protein kinase. (782 aa)
	L798_03791	Fibroblast growth factor receptor substrate 2. (570 aa)
	L798_07660	Phosphatidylinositol 3-kinase regulatory subunit alpha. (844 aa)
	L798_08498	Tyrosine-protein kinase. (528 aa)
	L798_00459	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (373 aa)
	L798_07676	SHC-transforming protein 1. (444 aa)
	L798_06440	Signal transducer and activator of transcription. (724 aa)
	L798_04523	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1060 aa)
	L798_06050	Protein daughter of sevenless. (814 aa)
	L798_00292	Ras-specific guanine nucleotide-releasing factor RalGPS1. (688 aa)
	L798_08699	Ras GTPase-activating protein 1. (930 aa)
	L798_07587	Signal-induced proliferation-associated 1-like protein 2. (1593 aa)
	L798_12386	Tyrosine-protein phosphatase non-receptor type 2. (476 aa)

Your Current Organism:

Zootermopsis nevadensis

NCBI taxonomy Id: 136037
Other names: Z. nevadensis

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L798_00292	L798_01386	A0A067RQP1	A0A067QWI7	Ras-specific guanine nucleotide-releasing factor RalGPS1.	Ras-like protein.	0.485
L798_00292	L798_02304	A0A067RQP1	A0A067QGM5	Ras-specific guanine nucleotide-releasing factor RalGPS1.	Ras-related protein Rap-2c.	0.485
L798_00292	L798_02525	A0A067RQP1	A0A067QHD4	Ras-specific guanine nucleotide-releasing factor RalGPS1.	Ras-like protein 1.	0.485
L798_00292	L798_03791	A0A067RQP1	A0A067RCV1	Ras-specific guanine nucleotide-releasing factor RalGPS1.	Fibroblast growth factor receptor substrate 2.	0.539
L798_00292	L798_04523	A0A067RQP1	A0A067RK76	Ras-specific guanine nucleotide-releasing factor RalGPS1.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.584
L798_00292	L798_05121	A0A067RQP1	A0A067RAW6	Ras-specific guanine nucleotide-releasing factor RalGPS1.	Cold shock domain-containing protein E1.	0.485
L798_00292	L798_07329	A0A067RQP1	A0A067R8J5	Ras-specific guanine nucleotide-releasing factor RalGPS1.	B-cell linker protein.	0.441
L798_00292	L798_07676	A0A067RQP1	A0A067RH42	Ras-specific guanine nucleotide-releasing factor RalGPS1.	SHC-transforming protein 1.	0.709
L798_00292	L798_08104	A0A067RQP1	A0A067R240	Ras-specific guanine nucleotide-releasing factor RalGPS1.	Receptor protein-tyrosine kinase.	0.763
L798_00292	L798_08498	A0A067RQP1	A0A067RF36	Ras-specific guanine nucleotide-releasing factor RalGPS1.	Tyrosine-protein kinase.	0.461
L798_00292	L798_09778	A0A067RQP1	A0A067R830	Ras-specific guanine nucleotide-releasing factor RalGPS1.	Ras-like protein 2.	0.485
L798_00292	L798_10187	A0A067RQP1	A0A067R5C3	Ras-specific guanine nucleotide-releasing factor RalGPS1.	GTP-binding protein Di-Ras2.	0.485
L798_00292	L798_10430	A0A067RQP1	A0A067QZE8	Ras-specific guanine nucleotide-releasing factor RalGPS1.	GTP-binding protein Rhes.	0.485
L798_00292	L798_11002	A0A067RQP1	A0A067QZW8	Ras-specific guanine nucleotide-releasing factor RalGPS1.	E3 ubiquitin-protein ligase CBL-B.	0.534
L798_00292	L798_11905	A0A067RQP1	A0A067R420	Ras-specific guanine nucleotide-releasing factor RalGPS1.	Uncharacterized protein.	0.655
L798_00292	L798_13300	A0A067RQP1	A0A067QTG7	Ras-specific guanine nucleotide-releasing factor RalGPS1.	Ras-like protein 3.	0.485
L798_00292	L798_13301	A0A067RQP1	A0A067QVC5	Ras-specific guanine nucleotide-releasing factor RalGPS1.	Spaetzle domain-containing protein.	0.485
L798_00292	L798_13674	A0A067RQP1	A0A067QZD3	Ras-specific guanine nucleotide-releasing factor RalGPS1.	Protein E(Sev)2B.	0.954
L798_00292	L798_13808	A0A067RQP1	A0A067QRW6	Ras-specific guanine nucleotide-releasing factor RalGPS1.	Raf-like protein serine/threonine-protein kinase phl.	0.431
L798_00292	L798_15019	A0A067RQP1	A0A067QYA8	Ras-specific guanine nucleotide-releasing factor RalGPS1.	GTP-binding protein Rit1.	0.485