(18 nodes) Positive regulation of ERK1 and ERK2 cascade network (Zootermopsis nevadensis)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	L798_13808	Raf-like protein serine/threonine-protein kinase phl. (675 aa)
	L798_15169	Connector enhancer of kinase suppressor of ras 2. (1871 aa)
	L798_14310	Tyrosine-protein kinase receptor. (1258 aa)
	L798_02227	Uncharacterized protein; Belongs to the cyclic nucleotide phosphodiesterase family. (745 aa)
	L798_01862	Protein aveugle. (110 aa)
	L798_02790	Rho GTPase-activating protein 1. (482 aa)
	L798_05776	Neuropeptide Y receptor type 2. (468 aa)
	L798_10313	Kinase suppressor of Ras 1. (929 aa)
	L798_11209	Protein sprouty. (428 aa)
	L798_09462	Dedicator of cytokinesis protein 3; Belongs to the DOCK family. (1611 aa)
	L798_09878	Receptor protein-tyrosine kinase. (1356 aa)
	L798_13674	Protein E(Sev)2B. (211 aa)
	L798_00224	Ubiquitin carboxyl-terminal hydrolase 47; Belongs to the peptidase C19 family. (1344 aa)
	L798_11478	Receptor protein-tyrosine kinase. (1430 aa)
	L798_01361	SH2B adapter protein 2. (563 aa)
	L798_13300	Ras-like protein 3. (157 aa)
	L798_13301	Spaetzle domain-containing protein. (209 aa)
	L798_00741	Cytohesin-1. (370 aa)

Your Current Organism:

Zootermopsis nevadensis

NCBI taxonomy Id: 136037
Other names: Z. nevadensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L798_01361	L798_13674	A0A067QVQ0	A0A067QZD3	SH2B adapter protein 2.	Protein E(Sev)2B.	0.671
L798_01862	L798_10313	A0A067RD26	A0A067R892	Protein aveugle.	Kinase suppressor of Ras 1.	0.476
L798_01862	L798_13808	A0A067RD26	A0A067QRW6	Protein aveugle.	Raf-like protein serine/threonine-protein kinase phl.	0.423
L798_01862	L798_15169	A0A067RD26	A0A067QNZ4	Protein aveugle.	Connector enhancer of kinase suppressor of ras 2.	0.502
L798_09878	L798_13674	A0A067QZT6	A0A067QZD3	Receptor protein-tyrosine kinase.	Protein E(Sev)2B.	0.719
L798_10313	L798_01862	A0A067R892	A0A067RD26	Kinase suppressor of Ras 1.	Protein aveugle.	0.476
L798_10313	L798_11209	A0A067R892	A0A067R888	Kinase suppressor of Ras 1.	Protein sprouty.	0.593
L798_10313	L798_13300	A0A067R892	A0A067QTG7	Kinase suppressor of Ras 1.	Ras-like protein 3.	0.594
L798_10313	L798_13301	A0A067R892	A0A067QVC5	Kinase suppressor of Ras 1.	Spaetzle domain-containing protein.	0.594
L798_10313	L798_13674	A0A067R892	A0A067QZD3	Kinase suppressor of Ras 1.	Protein E(Sev)2B.	0.506
L798_10313	L798_13808	A0A067R892	A0A067QRW6	Kinase suppressor of Ras 1.	Raf-like protein serine/threonine-protein kinase phl.	0.866
L798_10313	L798_15169	A0A067R892	A0A067QNZ4	Kinase suppressor of Ras 1.	Connector enhancer of kinase suppressor of ras 2.	0.820
L798_11209	L798_10313	A0A067R888	A0A067R892	Protein sprouty.	Kinase suppressor of Ras 1.	0.593
L798_11209	L798_13674	A0A067R888	A0A067QZD3	Protein sprouty.	Protein E(Sev)2B.	0.887
L798_11209	L798_13808	A0A067R888	A0A067QRW6	Protein sprouty.	Raf-like protein serine/threonine-protein kinase phl.	0.705
L798_11478	L798_13674	A0A067QWZ0	A0A067QZD3	Receptor protein-tyrosine kinase.	Protein E(Sev)2B.	0.719
L798_13300	L798_10313	A0A067QTG7	A0A067R892	Ras-like protein 3.	Kinase suppressor of Ras 1.	0.594
L798_13300	L798_13674	A0A067QTG7	A0A067QZD3	Ras-like protein 3.	Protein E(Sev)2B.	0.573
L798_13300	L798_13808	A0A067QTG7	A0A067QRW6	Ras-like protein 3.	Raf-like protein serine/threonine-protein kinase phl.	0.845
L798_13300	L798_15169	A0A067QTG7	A0A067QNZ4	Ras-like protein 3.	Connector enhancer of kinase suppressor of ras 2.	0.506