75 items (Zootermopsis nevadensis) - STRING interaction network

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	L798_13057	TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (448 aa)
	L798_04179	BRCA1-A complex subunit BRE. (388 aa)
	L798_11449	Uncharacterized protein. (161 aa)
	L798_01850	Ubiquitin. (229 aa)
	L798_12215	Lys-63-specific deubiquitinase BRCC36. (263 aa)
	L798_11187	Uncharacterized protein. (115 aa)
	L798_14995	Ubiquitin. (230 aa)
	L798_11781	Tumor suppressor p53-binding protein 1. (1553 aa)
	L798_14458	Uncharacterized protein. (141 aa)
	L798_00350	Uncharacterized protein. (1014 aa)
	L798_15274	DNA repair protein RAD51 homolog; Binds to single and double-stranded DNA and exhibits DNA- dependent ATPase activity. Underwinds duplex DNA. Belongs to the RecA family. RAD51 subfamily. (338 aa)
	L798_14243	DNA repair protein RAD50. (1311 aa)
	L798_13643	Asparaginyl-tRNA synthetase, cytoplasmic. (558 aa)
	L798_09937	Uncharacterized protein. (149 aa)
	L798_13806	DNA topoisomerase 2-binding protein 1. (1298 aa)
	L798_09756	DNA repair protein XRCC3. (379 aa)
	L798_09802	Crossover junction endonuclease MUS81. (602 aa)
	L798_09068	Uncharacterized protein. (145 aa)
	L798_08319	Uncharacterized protein. (174 aa)
	L798_08005	BRCA1-A complex subunit MERIT40. (332 aa)
	L798_07803	DNA repair protein XRCC2. (290 aa)
	L798_06967	Serine-protein kinase ATM; Belongs to the PI3/PI4-kinase family. (2066 aa)
	L798_07447	KxDL domain-containing protein. (222 aa)
	L798_12216	Lys-63-specific deubiquitinase BRCC36. (107 aa)
	L798_08531	Timeless-like protein. (1093 aa)
	L798_06657	Uncharacterized protein. (172 aa)
	L798_09841	Uncharacterized protein. (139 aa)
	L798_09604	DNA polymerase delta subunit 3. (484 aa)
	L798_10229	Serine/threonine-protein phosphatase. (307 aa)
	L798_10034	Gamma-glutamylcyclotransferase. (179 aa)
	L798_10442	Uncharacterized protein. (468 aa)
	L798_01129	Cell cycle checkpoint control protein; Belongs to the rad9 family. (428 aa)
	L798_08397	RCC1 and BTB domain-containing protein 1. (532 aa)
	L798_04938	Crossover junction endonuclease EME1. (413 aa)
	L798_04236	Cell division cycle-associated 7-like protein. (293 aa)
	L798_13237	Uncharacterized protein. (117 aa)
	L798_01187	Uncharacterized protein. (116 aa)
	L798_03794	Structure-specific endonuclease subunit SLX4. (413 aa)
	L798_12804	Serine/threonine-protein phosphatase 4 regulatory subunit 2. (549 aa)
	L798_14792	Uncharacterized protein. (164 aa)
	L798_02501	E3 ubiquitin-protein ligase RNF8. (97 aa)
	L798_12186	Uncharacterized protein. (165 aa)
	L798_05290	DNA repair protein RAD51-like protein 3. (332 aa)
	L798_12179	Ubiquitin. (77 aa)
	L798_07611	Serine/threonine-protein kinase grp. (503 aa)
	L798_01172	Putative E3 ubiquitin-protein ligase HERC2. (1940 aa)
	L798_03144	Breast cancer type 1 susceptibility protein-like protein. (650 aa)
	L798_07200	NAD-dependent deacetylase sirtuin-6. (411 aa)
	L798_06966	Serine-protein kinase ATM. (219 aa)
	L798_04103	Tudor domain-containing protein 3. (816 aa)
	L798_00484	Uncharacterized protein. (161 aa)
	L798_00096	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
	L798_12384	Ankyrin repeat domain-containing protein 11. (744 aa)
	L798_12802	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (463 aa)
	L798_07020	Double-strand break repair protein MRE11. (153 aa)
	L798_03457	DNA repair protein RAD51-like protein 4. (370 aa)
	L798_03342	Cell cycle checkpoint protein RAD17. (616 aa)
	L798_04486	Uncharacterized protein. (761 aa)
	L798_03034	DNA repair protein RAD52-like protein. (314 aa)
	L798_02644	Exonuclease 3'-5' domain-containing protein 2. (607 aa)
	L798_13402	Breast cancer type 2 susceptibility protein. (2968 aa)
	L798_13865	Uncharacterized protein. (106 aa)
	L798_03122	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (103 aa)
	L798_07584	E3 ubiquitin-protein ligase RNF8 A. (542 aa)
	L798_05101	Craniofacial development protein 2. (227 aa)
	L798_11393	G2/mitotic-specific cyclin-A; Belongs to the cyclin family. (424 aa)
	L798_14167	Craniofacial development protein 2. (140 aa)
	L798_14804	NAD-dependent deacetylase sirtuin-7. (821 aa)
	L798_00977	ATP-dependent DNA helicase Q4. (1386 aa)
	L798_05836	E3 ubiquitin-protein ligase RNF168. (653 aa)
	L798_01925	RecQ-mediated genome instability protein 1. (686 aa)
	L798_15108	Uncharacterized protein. (160 aa)
	L798_01773	Structure-specific endonuclease subunit slx1. (263 aa)
	L798_02126	E3 ubiquitin-protein ligase RNF8. (254 aa)
	L798_10113	Double-strand break repair protein MRE11A. (76 aa)

Your Current Organism:

Zootermopsis nevadensis

NCBI taxonomy Id: 136037
Other names: Z. nevadensis

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
L798_00096	L798_00977	A0A067RKT9	A0A067QLC4	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	ATP-dependent DNA helicase Q4.	0.932
L798_00096	L798_01129	A0A067RKT9	A0A067RBB5	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Cell cycle checkpoint control protein; Belongs to the rad9 family.	0.919
L798_00096	L798_01850	A0A067RKT9	A0A067QVQ6	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Ubiquitin.	0.403
L798_00096	L798_01925	A0A067RKT9	A0A067QK69	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	RecQ-mediated genome instability protein 1.	0.965
L798_00096	L798_02644	A0A067RKT9	A0A067QRJ3	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Exonuclease 3'-5' domain-containing protein 2.	0.716
L798_00096	L798_03034	A0A067RKT9	A0A067RDR2	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	DNA repair protein RAD52-like protein.	0.996
L798_00096	L798_03122	A0A067RKT9	A0A067QQ31	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Histone H4; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.	0.476
L798_00096	L798_03144	A0A067RKT9	A0A067REA2	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Breast cancer type 1 susceptibility protein-like protein.	0.721
L798_00096	L798_03342	A0A067RKT9	A0A067RD43	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Cell cycle checkpoint protein RAD17.	0.861
L798_00096	L798_03457	A0A067RKT9	A0A067RCD4	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	DNA repair protein RAD51-like protein 4.	0.846
L798_00096	L798_04103	A0A067RKT9	A0A067RDU6	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Tudor domain-containing protein 3.	0.654
L798_00096	L798_04236	A0A067RKT9	A0A067RC17	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Cell division cycle-associated 7-like protein.	0.732
L798_00096	L798_04486	A0A067RKT9	A0A067RD52	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Uncharacterized protein.	0.695
L798_00096	L798_05290	A0A067RKT9	A0A067RU08	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	DNA repair protein RAD51-like protein 3.	0.821
L798_00096	L798_06966	A0A067RKT9	A0A067RDX4	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Serine-protein kinase ATM.	0.720
L798_00096	L798_06967	A0A067RKT9	A0A067R4Q0	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Serine-protein kinase ATM; Belongs to the PI3/PI4-kinase family.	0.720
L798_00096	L798_07020	A0A067RKT9	A0A067RHP0	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Double-strand break repair protein MRE11.	0.802
L798_00096	L798_07611	A0A067RKT9	A0A067RWE0	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Serine/threonine-protein kinase grp.	0.727
L798_00096	L798_07803	A0A067RKT9	A0A067R4J8	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	DNA repair protein XRCC2.	0.512
L798_00096	L798_08531	A0A067RKT9	A0A067R5C9	Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage.	Timeless-like protein.	0.958