(16 nodes) Mixed, incl. Junctophilin, and Postsynaptic intermediate filament cytoskeleton network (Monodelphis domestica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	JPH4	Junctophilin 4. (641 aa)
	PRPH	Peripherin; Belongs to the intermediate filament family. (467 aa)
	JPH3	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (755 aa)
	JPH1	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (659 aa)
	NEFH	Neurofilament heavy; Belongs to the intermediate filament family. (1027 aa)
	INA	Internexin neuronal intermediate filament protein alpha; Belongs to the intermediate filament family. (538 aa)
	WDR44	WD repeat domain 44. (907 aa)
	SYNM	Uncharacterized protein. (811 aa)
	NEFM	IF rod domain-containing protein; Belongs to the intermediate filament family. (931 aa)
	SYNC	Syncoilin, intermediate filament protein; Belongs to the intermediate filament family. (508 aa)
	NEFL	Neurofilament light; Belongs to the intermediate filament family. (550 aa)
	CLEC16A	C-type lectin domain containing 16A. (1049 aa)
	ENSMODP00000047579	Uncharacterized protein. (103 aa)
	JPH2	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels. (742 aa)
	LOC100029905	NACHT domain-containing protein. (1187 aa)
	ENSMODP00000059895	IF rod domain-containing protein; Belongs to the intermediate filament family. (402 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLEC16A	WDR44	ENSMODP00000042541	ENSMODP00000014118	C-type lectin domain containing 16A.	WD repeat domain 44.	0.723
ENSMODP00000047579	JPH4	ENSMODP00000047579	ENSMODP00000004635	Uncharacterized protein.	Junctophilin 4.	0.443
ENSMODP00000059895	SYNC	ENSMODP00000059895	ENSMODP00000021731	IF rod domain-containing protein; Belongs to the intermediate filament family.	Syncoilin, intermediate filament protein; Belongs to the intermediate filament family.	0.403
ENSMODP00000059895	SYNM	ENSMODP00000059895	ENSMODP00000015956	IF rod domain-containing protein; Belongs to the intermediate filament family.	Uncharacterized protein.	0.853
INA	NEFH	ENSMODP00000013924	ENSMODP00000011115	Internexin neuronal intermediate filament protein alpha; Belongs to the intermediate filament family.	Neurofilament heavy; Belongs to the intermediate filament family.	0.619
INA	NEFL	ENSMODP00000013924	ENSMODP00000027974	Internexin neuronal intermediate filament protein alpha; Belongs to the intermediate filament family.	Neurofilament light; Belongs to the intermediate filament family.	0.860
INA	NEFM	ENSMODP00000013924	ENSMODP00000020899	Internexin neuronal intermediate filament protein alpha; Belongs to the intermediate filament family.	IF rod domain-containing protein; Belongs to the intermediate filament family.	0.609
JPH1	JPH2	ENSMODP00000008619	ENSMODP00000049072	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.552
JPH1	JPH3	ENSMODP00000008619	ENSMODP00000005464	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.550
JPH1	JPH4	ENSMODP00000008619	ENSMODP00000004635	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Junctophilin 4.	0.618
JPH2	JPH1	ENSMODP00000049072	ENSMODP00000008619	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.552
JPH2	JPH3	ENSMODP00000049072	ENSMODP00000005464	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.553
JPH2	JPH4	ENSMODP00000049072	ENSMODP00000004635	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Junctophilin 4.	0.618
JPH3	JPH1	ENSMODP00000005464	ENSMODP00000008619	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.550
JPH3	JPH2	ENSMODP00000005464	ENSMODP00000049072	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.553
JPH3	JPH4	ENSMODP00000005464	ENSMODP00000004635	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	Junctophilin 4.	0.619
JPH4	ENSMODP00000047579	ENSMODP00000004635	ENSMODP00000047579	Junctophilin 4.	Uncharacterized protein.	0.443
JPH4	JPH1	ENSMODP00000004635	ENSMODP00000008619	Junctophilin 4.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.618
JPH4	JPH2	ENSMODP00000004635	ENSMODP00000049072	Junctophilin 4.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.618
JPH4	JPH3	ENSMODP00000004635	ENSMODP00000005464	Junctophilin 4.	Junctophilin; Junctophilins contribute to the formation of junctional membrane complexes (JMCs) which link the plasma membrane with the endoplasmic or sarcoplasmic reticulum in excitable cells. Provides a structural foundation for functional cross-talk between the cell surface and intracellular calcium release channels.	0.619