(11 nodes) Mixed, incl. Interleukin-2 signaling, and Interleukin 7 network (Monodelphis domestica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IL2RB	Fibronectin type-III domain-containing protein. (562 aa)
	IL2RG	Fibronectin type-III domain-containing protein. (301 aa)
	IL7R	Fibronectin type-III domain-containing protein. (456 aa)
	JAK3	Tyrosine-protein kinase. (1097 aa)
	K7E4W0_MONDO	Fibronectin type-III domain-containing protein. (529 aa)
	CRLF2	Uncharacterized protein. (369 aa)
	IL9	Uncharacterized protein. (167 aa)
	IL15	Interleukin; Belongs to the IL-15/IL-21 family. (183 aa)
	IL7	Uncharacterized protein. (205 aa)
	IL2	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (142 aa)
	IL15RA	Sushi domain-containing protein. (295 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CRLF2	IL15	ENSMODP00000041017	ENSMODP00000042052	Uncharacterized protein.	Interleukin; Belongs to the IL-15/IL-21 family.	0.674
CRLF2	IL2	ENSMODP00000041017	ENSMODP00000052096	Uncharacterized protein.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.684
CRLF2	IL7	ENSMODP00000041017	ENSMODP00000049727	Uncharacterized protein.	Uncharacterized protein.	0.830
CRLF2	IL7R	ENSMODP00000041017	ENSMODP00000025476	Uncharacterized protein.	Fibronectin type-III domain-containing protein.	0.997
CRLF2	IL9	ENSMODP00000041017	ENSMODP00000041312	Uncharacterized protein.	Uncharacterized protein.	0.697
CRLF2	JAK3	ENSMODP00000041017	ENSMODP00000032098	Uncharacterized protein.	Tyrosine-protein kinase.	0.400
IL15	CRLF2	ENSMODP00000042052	ENSMODP00000041017	Interleukin; Belongs to the IL-15/IL-21 family.	Uncharacterized protein.	0.674
IL15	IL15RA	ENSMODP00000042052	ENSMODP00000058501	Interleukin; Belongs to the IL-15/IL-21 family.	Sushi domain-containing protein.	0.998
IL15	IL2	ENSMODP00000042052	ENSMODP00000052096	Interleukin; Belongs to the IL-15/IL-21 family.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.652
IL15	IL2RB	ENSMODP00000042052	ENSMODP00000000796	Interleukin; Belongs to the IL-15/IL-21 family.	Fibronectin type-III domain-containing protein.	0.910
IL15	IL2RG	ENSMODP00000042052	ENSMODP00000006262	Interleukin; Belongs to the IL-15/IL-21 family.	Fibronectin type-III domain-containing protein.	0.910
IL15	IL7	ENSMODP00000042052	ENSMODP00000049727	Interleukin; Belongs to the IL-15/IL-21 family.	Uncharacterized protein.	0.706
IL15	IL7R	ENSMODP00000042052	ENSMODP00000025476	Interleukin; Belongs to the IL-15/IL-21 family.	Fibronectin type-III domain-containing protein.	0.913
IL15	IL9	ENSMODP00000042052	ENSMODP00000041312	Interleukin; Belongs to the IL-15/IL-21 family.	Uncharacterized protein.	0.676
IL15	JAK3	ENSMODP00000042052	ENSMODP00000032098	Interleukin; Belongs to the IL-15/IL-21 family.	Tyrosine-protein kinase.	0.836
IL15	K7E4W0_MONDO	ENSMODP00000042052	ENSMODP00000040812	Interleukin; Belongs to the IL-15/IL-21 family.	Fibronectin type-III domain-containing protein.	0.665
IL15RA	IL15	ENSMODP00000058501	ENSMODP00000042052	Sushi domain-containing protein.	Interleukin; Belongs to the IL-15/IL-21 family.	0.998
IL15RA	IL2	ENSMODP00000058501	ENSMODP00000052096	Sushi domain-containing protein.	Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family.	0.895
IL15RA	IL2RB	ENSMODP00000058501	ENSMODP00000000796	Sushi domain-containing protein.	Fibronectin type-III domain-containing protein.	0.821
IL15RA	IL2RG	ENSMODP00000058501	ENSMODP00000006262	Sushi domain-containing protein.	Fibronectin type-III domain-containing protein.	0.821