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SDHA SDHA PDHB PDHB SUCLG2 SUCLG2 DLST DLST FH FH PDK3 PDK3 BCKDHA BCKDHA IDH3G IDH3G PDK1 PDK1 SUCLA2 SUCLA2 GCDH GCDH IDH3A IDH3A PDK2 PDK2 IDH1 IDH1 MDH1B MDH1B OGDH OGDH DLD DLD ACO2 ACO2 DHTKD1 DHTKD1 BCKDHB BCKDHB IDH2 IDH2 SUCLG1 SUCLG1 PDHX PDHX OGDHL OGDHL K7E0Z8_MONDO K7E0Z8_MONDO DLAT DLAT SDHC SDHC PDHA1 PDHA1 ENSMODP00000049451 ENSMODP00000049451 IDH3B IDH3B DBT DBT ENSMODP00000051781 ENSMODP00000051781 SDHB SDHB SDHD SDHD ACO1 ACO1 ENSMODP00000059993 ENSMODP00000059993
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (371 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (541 aa)
DLSTDihydrolipoamide S-succinyltransferase. (456 aa)
FHFumarate hydratase. (504 aa)
PDK3Protein-serine/threonine kinase. (415 aa)
BCKDHA2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (439 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (538 aa)
PDK1Protein-serine/threonine kinase. (427 aa)
SUCLA2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (464 aa)
GCDHGlutaryl-CoA dehydrogenase. (429 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
PDK2Protein-serine/threonine kinase. (407 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
MDH1BUncharacterized protein. (432 aa)
OGDHOxoglutarate dehydrogenase. (1020 aa)
DLDDihydrolipoyl dehydrogenase. (468 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (923 aa)
BCKDHBBranched chain keto acid dehydrogenase E1 subunit beta. (383 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (455 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (371 aa)
PDHXDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (498 aa)
OGDHLOxoglutarate dehydrogenase like. (800 aa)
K7E0Z8_MONDOProtein-serine/threonine kinase. (267 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (643 aa)
SDHCSuccinate dehydrogenase complex subunit C. (217 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (411 aa)
ENSMODP00000049451E1_dh domain-containing protein. (101 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (376 aa)
DBTDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (503 aa)
ENSMODP00000051781Pyr_redox_2 domain-containing protein. (132 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (292 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (173 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (914 aa)
ENSMODP00000059993Uncharacterized protein. (70 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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