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| | INCENP | Inner centromere protein. (909 aa) |
| | BRCA2 | Tower domain-containing protein. (3324 aa) |
| | ADD3 | Adducin 3. (752 aa) |
| | F6Y4F4_MONDO | Uncharacterized protein. (2906 aa) |
| | RAD21L1 | RAD21 cohesin complex component like 1. (576 aa) |
| | SPO11 | SPO11 initiator of meiotic double stranded breaks. (393 aa) |
| | GINS3 | GINS complex subunit 3. (219 aa) |
| | SMARCB1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1. (282 aa) |
| | SMCHD1 | SMC hinge domain-containing protein. (612 aa) |
| | LOC100027246 | Uncharacterized protein. (298 aa) |
| | RAD1 | RAD1 checkpoint DNA exonuclease. (281 aa) |
| | PRPF19 | Pre-mRNA processing factor 19. (504 aa) |
| | BLM | BLM RecQ like helicase. (1451 aa) |
| | PHF12 | PHD finger protein 12. (1057 aa) |
| | EXOSC9 | Exosome component 9. (438 aa) |
| | MCM3 | DNA helicase; Belongs to the MCM family. (810 aa) |
| | HORMAD1 | HORMA domain containing 1. (395 aa) |
| | PRIM2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (508 aa) |
| | SAP130 | Sin3A associated protein 130. (1057 aa) |
| | MEI4 | Meiotic double-stranded break formation protein 4. (399 aa) |
| | MMS22L | MMS22 like, DNA repair protein. (1241 aa) |
| | HDAC2 | Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa) |
| | RPA3 | Replication protein A3. (120 aa) |
| | HDAC1 | Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (450 aa) |
| | KMT2E | Lysine methyltransferase 2E. (1748 aa) |
| | ORC5 | Origin recognition complex subunit 5. (435 aa) |
| | MCM10 | Minichromosome maintenance 10 replication initiation factor. (878 aa) |
| | SLX4 | BTB domain-containing protein. (1839 aa) |
| | POLD2 | DNA polymerase delta 2, accessory subunit. (562 aa) |
| | SRCAP | Uncharacterized protein. (3117 aa) |
| | ZMIZ2 | Zinc finger MIZ-type containing 2. (928 aa) |
| | INO80E | INO80 complex subunit E. (245 aa) |
| | F7EIL2_MONDO | GIY-YIG domain-containing protein. (165 aa) |
| | SMARCAL1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (965 aa) |
| | EP400 | E1A binding protein p400. (2929 aa) |
| | SUDS3 | SDS3 homolog, SIN3A corepressor complex component. (327 aa) |
| | POLE | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2125 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1840 aa) |
| | ORC2 | Origin recognition complex subunit 2. (575 aa) |
| | SIN3B | SIN3 transcription regulator family member B. (1122 aa) |
| | NUFIP1 | C2H2-type domain-containing protein. (469 aa) |
| | PSMC3IP | Uncharacterized protein. (218 aa) |
| | C17orf64 | Chromosome 17 open reading frame 64. (262 aa) |
| | RAD50 | Zinc-hook domain-containing protein. (1330 aa) |
| | TRIM24 | Tripartite motif containing 24. (1060 aa) |
| | FKBP6 | Peptidylprolyl isomerase. (453 aa) |
| | LRWD1 | Leucine rich repeats and WD repeat domain containing 1. (693 aa) |
| | MLH1 | MutL homolog 1. (731 aa) |
| | TOP2A | DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1557 aa) |
| | BAZ1A | Bromodomain adjacent to zinc finger domain 1A. (1556 aa) |
| | ORC6 | Origin recognition complex subunit 6. (249 aa) |
| | BRMS1L | BRMS1 like transcriptional repressor. (323 aa) |
| | ACTR8 | Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa) |
| | BRD8 | Bromodomain containing 8. (1316 aa) |
| | F7FST0_MONDO | TBPIP domain-containing protein. (84 aa) |
| | WDHD1 | WD repeat and HMG-box DNA binding protein 1. (1134 aa) |
| | PCNA | Proliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa) |
| | RAD9B | Cell cycle checkpoint control protein; Belongs to the rad9 family. (404 aa) |
| | TOPBP1 | DNA topoisomerase II binding protein 1. (1512 aa) |
| | F6RJQ6_MONDO | Dpoe2NT domain-containing protein. (93 aa) |
| | POLE4 | DNA polymerase epsilon 4, accessory subunit. (162 aa) |
| | TONSL | Tonsoku like, DNA repair protein. (1363 aa) |
| | RPA1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (617 aa) |
| | F6ZF24_MONDO | Uncharacterized protein. (381 aa) |
| | GINS4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa) |
| | MCM4 | DNA helicase; Belongs to the MCM family. (864 aa) |
| | CDC45 | Cell division cycle 45. (527 aa) |
| | POLA2 | DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (587 aa) |
| | TIPIN | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (286 aa) |
| | DMC1 | Meiotic recombination protein; May participate in meiotic recombination, specifically in homologous strand assimilation, which is required for the resolution of meiotic double-strand breaks; Belongs to the RecA family. DMC1 subfamily. (342 aa) |
| | KAT5 | Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (617 aa) |
| | HUS1 | Checkpoint protein; Belongs to the HUS1 family. (280 aa) |
| | CDX2 | Caudal type homeobox 2. (302 aa) |
| | PINX1 | PIN2 (TERF1) interacting telomerase inhibitor 1. (330 aa) |
| | NCAPH | Condensin complex subunit 2; Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. (735 aa) |
| | F7GF12_MONDO | RRM domain-containing protein. (279 aa) |
| | RUVBL1 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa) |
| | MCM2 | DNA helicase; Belongs to the MCM family. (905 aa) |
| | ARID4A | AT-rich interaction domain 4A. (1280 aa) |
| | F7FN78_MONDO | Uncharacterized protein. (349 aa) |
| | RAD9A | Cell cycle checkpoint control protein; Belongs to the rad9 family. (461 aa) |
| | SMC4 | Structural maintenance of chromosomes protein. (1237 aa) |
| | ENSMODP00000059889 | Uncharacterized protein. (976 aa) |
| | CHEK1 | Checkpoint kinase 1; Belongs to the protein kinase superfamily. (476 aa) |
| | SPIDR | DUF4502 domain-containing protein. (235 aa) |
| | INO80D | INO80 complex subunit D. (1028 aa) |
| | SETD5 | SET domain containing 5. (1518 aa) |
| | BRD4 | Uncharacterized protein. (692 aa) |
| | ENSMODP00000058640 | Uncharacterized protein. (85 aa) |
| | SMC1A | Structural maintenance of chromosomes protein. (1234 aa) |
| | SYCE1L | Uncharacterized protein. (199 aa) |
| | ENSMODP00000058159 | Uncharacterized protein. (54 aa) |
| | DNMT3L | PHD-type domain-containing protein. (449 aa) |
| | RCC1 | Regulator of chromosome condensation 1. (430 aa) |
| | ATRX | ATRX chromatin remodeler. (2389 aa) |
| | SETX | Senataxin. (2804 aa) |
| | POLA1 | DNA polymerase. (1499 aa) |
| | SMC1B | Structural maintenance of chromosomes protein. (1283 aa) |
| | CCNB1IP1 | Cyclin B1 interacting protein 1. (277 aa) |
| | SMC2 | Structural maintenance of chromosomes protein. (1197 aa) |
| | MACROH2A2 | H2A histone family member Y2. (347 aa) |
| | RUVBL2 | RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (475 aa) |
| | KIFAP3 | Kinesin associated protein 3. (826 aa) |
| | CCDC36 | Uncharacterized protein. (495 aa) |
| | ENSMODP00000046382 | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (84 aa) |
| | ENSMODP00000047016 | Uncharacterized protein. (91 aa) |
| | HORMAD2 | HORMA domain-containing protein. (426 aa) |
| | CFDP1 | Craniofacial development protein 1; May play a role during embryogenesis. (332 aa) |
| | UCHL5 | Ubiquitin carboxyl-terminal hydrolase. (369 aa) |
| | GINS1 | Uncharacterized protein. (385 aa) |
| | ZRANB3 | Zinc finger RANBP2-type containing 3. (1091 aa) |
| | MSH4 | MutS homolog 4. (881 aa) |
| | SYCP3 | Cor1 domain-containing protein. (241 aa) |
| | ORC3 | Origin recognition complex subunit 3. (727 aa) |
| | ENSMODP00000051191 | MCM domain-containing protein; Belongs to the MCM family. (359 aa) |
| | CCDC155 | KASH_CCD domain-containing protein. (379 aa) |
| | ACTR6 | Actin related protein 6; Belongs to the actin family. (396 aa) |
| | SYCE2 | Uncharacterized protein. (116 aa) |
| | ENSMODP00000052423 | Uncharacterized protein. (452 aa) |
| | ENSMODP00000053346 | Uncharacterized protein. (287 aa) |
| | FAM60A | Uncharacterized protein. (168 aa) |
| | TRRAP | Transformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3796 aa) |
| | MCM5 | DNA helicase; Belongs to the MCM family. (759 aa) |
| | ZNHIT1 | Zinc finger HIT-type containing 1. (246 aa) |
| | SMARCAD1 | Uncharacterized protein. (1099 aa) |
| | NOL6 | Nucleolar protein 6. (1198 aa) |
| | NCAPH2 | CNDH2_N domain-containing protein. (225 aa) |
| | NCAPG2 | Non-SMC condensin II complex subunit G2. (1140 aa) |
| | ING3 | Inhibitor of growth protein. (417 aa) |
| | POLD3 | DNA polymerase delta 3, accessory subunit. (466 aa) |
| | DHX9 | DExH-box helicase 9. (1259 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (614 aa) |
| | HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (837 aa) |
| | MLH3 | MutL homolog 3. (1475 aa) |
| | C6H9orf84 | Uncharacterized protein. (1483 aa) |
| | F7FKP9_MONDO | Uncharacterized protein. (679 aa) |
| | NFRKB | Nuclear factor related to kappaB binding protein. (1302 aa) |
| | SYCP1 | Synaptonemal complex protein 1. (1000 aa) |
| | GINS2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa) |
| | RNF212B | Ring finger protein 212B. (301 aa) |
| | STAG3 | Stromal antigen 3. (1242 aa) |
| | POLE3 | CBFD_NFYB_HMF domain-containing protein. (146 aa) |
| | MCRS1 | Microspherule protein 1. (462 aa) |
| | ING2 | Inhibitor of growth protein. (281 aa) |
| | RAD21 | RAD21 cohesin complex component. (634 aa) |
| | TFPT | TCF3 fusion partner. (246 aa) |
| | F6Z0A4_MONDO | Structural maintenance of chromosomes protein. (1216 aa) |
| | REC8 | REC8 meiotic recombination protein. (609 aa) |
| | ORC4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (436 aa) |
| | SIRT7 | Sirtuin 7. (521 aa) |
| | E2F1 | E2F transcription factor 1. (443 aa) |
| | NEK2 | NIMA related kinase 2. (445 aa) |
| | DMAP1 | DNA methyltransferase 1 associated protein 1. (462 aa) |
| | LRIF1 | Ligand dependent nuclear receptor interacting factor 1. (763 aa) |
| | MCM6 | DNA helicase; Belongs to the MCM family. (821 aa) |
| | LRPPRC | Leucine rich pentatricopeptide repeat containing. (1404 aa) |
| | INO80C | INO80 complex subunit C. (189 aa) |
| | ACTR5 | Actin related protein 5; Belongs to the actin family. (593 aa) |
| | BCAS2 | BCAS2 pre-mRNA processing factor. (225 aa) |
| | RAD51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa) |
| | INO80 | INO80 complex ATPase subunit. (1558 aa) |
| | NIFK | RRM domain-containing protein. (258 aa) |
| | STAG2 | Stromal antigen 2. (1267 aa) |
| | WAPL | WAPL cohesin release factor. (1229 aa) |
| | TIMELESS | TIMELESS domain-containing protein. (560 aa) |
| | MACROH2A1 | H2A histone family member Y. (406 aa) |
| | SYCE3 | Synaptonemal complex central element protein 3. (84 aa) |
| | CPSF6 | RRM domain-containing protein. (589 aa) |
| | LOC100012142 | Uncharacterized protein. (250 aa) |
| | RNF212 | RING-type domain-containing protein. (296 aa) |
| | MCM7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (725 aa) |
| | C14orf39 | Chromosome 14 open reading frame 39. (584 aa) |
| | SYCP2L | Uncharacterized protein. (852 aa) |
| | ORC1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (871 aa) |
| | SIN3A | SIN3 transcription regulator family member A. (1274 aa) |
| | SUN2 | Sad1 and UNC84 domain containing 2. (672 aa) |
| | RRS1 | Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (363 aa) |
| | SMC3 | Structural maintenance of chromosomes protein. (1218 aa) |
| | NCAPG | Non-SMC condensin I complex subunit G. (923 aa) |
