(93 nodes) Neuron migration network (Monodelphis domestica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	C2H17orf47	Uncharacterized protein. (543 aa)
	ALKBH1	AlkB homolog 1, histone H2A dioxygenase. (381 aa)
	KIRREL3	Kirre like nephrin family adhesion molecule 3. (778 aa)
	NDE1	NudE neurodevelopment protein 1. (347 aa)
	NR4A2	Nuclear receptor subfamily 4 group A member 2. (598 aa)
	GAS6	Growth arrest specific 6. (677 aa)
	SH3RF1	SH3 domain containing ring finger 1. (871 aa)
	FEZF2	FEZ family zinc finger 2. (487 aa)
	PEX13	Peroxisomal biogenesis factor 13. (422 aa)
	ZMIZ1	Zinc finger MIZ-type containing 1. (933 aa)
	NAV1	Neuron navigator 1. (1858 aa)
	EVX1	Even-skipped homeobox 1. (409 aa)
	CCKAR	Cholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family. (429 aa)
	TYRO3	TYRO3 protein tyrosine kinase. (820 aa)
	TBX20	T-box transcription factor 20. (456 aa)
	DDIT4	DNA damage inducible transcript 4. (226 aa)
	AUTS2	Activator of transcription and developmental regulator AUTS2. (1051 aa)
	ARX	Aristaless related homeobox. (537 aa)
	NRP1	Neuropilin; Belongs to the neuropilin family. (922 aa)
	UNK	Unk zinc finger. (764 aa)
	GATA2	GATA binding protein 2. (473 aa)
	BBS1	BBS1 domain-containing protein. (559 aa)
	ELP3	Elongator complex protein 3; Catalytic tRNA acetyltransferase subunit of the RNA polymerase II elongator complex, which is a component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. (547 aa)
	FZD3	Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
	EMX2	Empty spiracles homeobox 2. (248 aa)
	YWHAE	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family. (251 aa)
	CRK	CRK proto-oncogene, adaptor protein. (297 aa)
	COL3A1	Collagen type III alpha 1 chain. (1461 aa)
	CCR4	C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (354 aa)
	DCC	DCC netrin 1 receptor. (1403 aa)
	CCK	Gastrin domain-containing protein. (126 aa)
	CTNNB1	Catenin beta 1. (781 aa)
	BARHL2	BarH like homeobox 2. (290 aa)
	BARHL1	BarH like homeobox 1. (327 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (415 aa)
	TOP2B	DNA topoisomerase 2; Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double- strand breaks. (1631 aa)
	EOMES	Uncharacterized protein. (665 aa)
	FEZF1	FEZ family zinc finger 1. (465 aa)
	PRKG1	Protein kinase cGMP-dependent 1; Belongs to the protein kinase superfamily. (455 aa)
	F6ZDL1_MONDO	Cyclic nucleotide-binding domain-containing protein. (232 aa)
	GATA3	GATA binding protein 3. (444 aa)
	SEMA3E	Semaphorin 3E; Belongs to the semaphorin family. (715 aa)
	CDKL5	Cyclin dependent kinase like 5. (945 aa)
	FOXG1	Forkhead box G1. (492 aa)
	CRKL	Uncharacterized protein. (303 aa)
	CEP85L	Centrosomal protein 85 like. (799 aa)
	KIAA0319L	KIAA0319 like. (1129 aa)
	PEX5	Peroxisomal biogenesis factor 5. (645 aa)
	TUBGCP2	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (685 aa)
	VEGFA	Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (445 aa)
	SRF	Serum response factor. (490 aa)
	ATOH1	Atonal bHLH transcription factor 1. (380 aa)
	ASTN2	Astrotactin 2. (1352 aa)
	PHOX2B	Homeobox domain-containing protein. (314 aa)
	PAFAH1B1	Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (409 aa)
	CDK5R1	Cyclin-dependent kinase 5 activator. (306 aa)
	AXL	AXL receptor tyrosine kinase. (886 aa)
	PAX6	Paired box 6. (221 aa)
	DNAAF4	Dynein axonemal assembly factor 4. (450 aa)
	SEMA3A	Semaphorin 3A; Belongs to the semaphorin family. (772 aa)
	NTRK2	Tyrosine-protein kinase receptor. (750 aa)
	DAB1	DAB adaptor protein 1. (551 aa)
	GPM6A	Glycoprotein M6A. (299 aa)
	ENSMODP00000043154	Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (585 aa)
	MDGA2	MAM domain containing glycosylphosphatidylinositol anchor 2. (1004 aa)
	ITGA3	Integrin subunit alpha 3; Belongs to the integrin alpha chain family. (1021 aa)
	PEX7	Peroxisomal biogenesis factor 7. (341 aa)
	ASTN1	Astrotactin 1. (1322 aa)
	NRP2	Neuropilin; Belongs to the neuropilin family. (931 aa)
	PCM1	Pericentriolar material 1. (2176 aa)
	FBXO45	Uncharacterized protein. (284 aa)
	ADGRL3	Adhesion G protein-coupled receptor L3; Belongs to the G-protein coupled receptor 2 family. (1471 aa)
	NDNF	Uncharacterized protein. (569 aa)
	BBS4	Bardet-Biedl syndrome 4. (621 aa)
	DCLK1	Doublecortin like kinase 1. (740 aa)
	TRIM46	Tripartite motif containing 46. (502 aa)
	POMGNT2	Protein O-linked mannose N-acetylglucosaminyltransferase 2 (beta 1,4-). (627 aa)
	ENSMODP00000053169	Uncharacterized protein. (59 aa)
	FGF13	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (249 aa)
	DISC1	Uncharacterized protein. (901 aa)
	RELN	Reelin. (3458 aa)
	RAPGEF2	Rap guanine nucleotide exchange factor 2. (1703 aa)
	CDK5R2	Cyclin-dependent kinase 5 activator. (361 aa)
	CNTN2	Contactin 2. (1036 aa)
	ENSMODP00000057195	SH2 domain-containing protein. (119 aa)
	ENSMODP00000057249	Uncharacterized protein. (205 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (516 aa)
	CELSR2	Cadherin EGF LAG seven-pass G-type receptor 2; Belongs to the G-protein coupled receptor 2 family. (2914 aa)
	CDK5	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	SDCCAG8	Uncharacterized protein. (938 aa)
	FAT3	FAT atypical cadherin 3. (4612 aa)
	NEO1	Neogenin 1. (1576 aa)
	BAX	Uncharacterized protein. (296 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARX	CDKL5	ENSMODP00000009070	ENSMODP00000021387	Aristaless related homeobox.	Cyclin dependent kinase like 5.	0.433
ATOH1	BARHL1	ENSMODP00000024053	ENSMODP00000015700	Atonal bHLH transcription factor 1.	BarH like homeobox 1.	0.553
ATOH1	PAX6	ENSMODP00000024053	ENSMODP00000034398	Atonal bHLH transcription factor 1.	Paired box 6.	0.460
ATOH1	PHOX2B	ENSMODP00000024053	ENSMODP00000025734	Atonal bHLH transcription factor 1.	Homeobox domain-containing protein.	0.403
AUTS2	YWHAE	ENSMODP00000008495	ENSMODP00000012735	Activator of transcription and developmental regulator AUTS2.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon; Belongs to the 14-3-3 family.	0.406
AXL	GAS6	ENSMODP00000031323	ENSMODP00000004449	AXL receptor tyrosine kinase.	Growth arrest specific 6.	0.964
BARHL1	ATOH1	ENSMODP00000015700	ENSMODP00000024053	BarH like homeobox 1.	Atonal bHLH transcription factor 1.	0.553
BBS1	BBS4	ENSMODP00000010171	ENSMODP00000051495	BBS1 domain-containing protein.	Bardet-Biedl syndrome 4.	0.995
BBS1	DNAAF4	ENSMODP00000010171	ENSMODP00000034471	BBS1 domain-containing protein.	Dynein axonemal assembly factor 4.	0.409
BBS1	PCM1	ENSMODP00000010171	ENSMODP00000048786	BBS1 domain-containing protein.	Pericentriolar material 1.	0.444
BBS1	SDCCAG8	ENSMODP00000010171	ENSMODP00000058494	BBS1 domain-containing protein.	Uncharacterized protein.	0.449
BBS4	BBS1	ENSMODP00000051495	ENSMODP00000010171	Bardet-Biedl syndrome 4.	BBS1 domain-containing protein.	0.995
BBS4	DISC1	ENSMODP00000051495	ENSMODP00000054450	Bardet-Biedl syndrome 4.	Uncharacterized protein.	0.496
BBS4	PCM1	ENSMODP00000051495	ENSMODP00000048786	Bardet-Biedl syndrome 4.	Pericentriolar material 1.	0.860
CCK	CCKAR	ENSMODP00000013851	ENSMODP00000000121	Gastrin domain-containing protein.	Cholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family.	0.996
CCK	CTNNB1	ENSMODP00000013851	ENSMODP00000014004	Gastrin domain-containing protein.	Catenin beta 1.	0.455
CCKAR	CCK	ENSMODP00000000121	ENSMODP00000013851	Cholecystokinin A receptor; Belongs to the G-protein coupled receptor 1 family.	Gastrin domain-containing protein.	0.996
CDK5	CDK5R1	ENSMODP00000057999	ENSMODP00000028842	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Cyclin-dependent kinase 5 activator.	0.995
CDK5	CDK5R2	ENSMODP00000057999	ENSMODP00000055949	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	Cyclin-dependent kinase 5 activator.	0.959
CDK5	NDE1	ENSMODP00000057999	ENSMODP00000005403	Cyclin dependent kinase 5; Belongs to the protein kinase superfamily.	NudE neurodevelopment protein 1.	0.408