(33 nodes) Morphogenesis of an epithelial sheet network (Monodelphis domestica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSMODP00000057968	Homeobox B4. (240 aa)
	LRG1	Uncharacterized protein. (356 aa)
	FLRT3	Fibronectin leucine rich transmembrane protein 3. (649 aa)
	DVL1	Dishevelled segment polarity protein 1. (705 aa)
	TOR1A	Torsin. (335 aa)
	ARHGAP12	Rho GTPase activating protein 12. (879 aa)
	SOS1	SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa)
	VAX1	Ventral anterior homeobox 1. (326 aa)
	MPP5	Membrane palmitoylated protein 5; Belongs to the MAGUK family. (675 aa)
	PHACTR4	Phosphatase and actin regulator. (717 aa)
	HBEGF	Heparin binding EGF like growth factor. (208 aa)
	TMEFF2	Transmembrane protein with EGF like and two follistatin like domains 2. (374 aa)
	HOXB2	Homeobox B2. (365 aa)
	ADAM17	ADAM metallopeptidase domain 17. (747 aa)
	DDR1	Discoidin domain receptor tyrosine kinase 1. (911 aa)
	BMP7	Bone morphogenetic protein 7. (432 aa)
	BMP5	Bone morphogenetic protein 5. (455 aa)
	SRF	Serum response factor. (490 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1276 aa)
	PDCD10	Uncharacterized protein. (149 aa)
	PLET1	Reelin domain-containing protein. (188 aa)
	ENSMODP00000041408	Uncharacterized protein. (134 aa)
	AJUBA	Ajuba LIM protein. (537 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (713 aa)
	LAMA1	Laminin subunit alpha 1. (2951 aa)
	FLNA	Filamin A. (2558 aa)
	CCN1	Cellular communication network factor 1. (383 aa)
	ENSMODP00000048395	Link domain-containing protein. (346 aa)
	DAG1	Dystroglycan 1. (896 aa)
	ARHGAP35	Rho GTPase activating protein 35. (1499 aa)
	MRTFA	SAP domain-containing protein. (636 aa)
	ENSMODP00000057314	Uncharacterized protein. (425 aa)
	TBX20	T-box transcription factor 20. (456 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADAM17	HBEGF	ENSMODP00000018410	ENSMODP00000014655	ADAM metallopeptidase domain 17.	Heparin binding EGF like growth factor.	0.438
AJUBA	FLNA	ENSMODP00000041500	ENSMODP00000044463	Ajuba LIM protein.	Filamin A.	0.422
DAG1	LAMA1	ENSMODP00000048755	ENSMODP00000042084	Dystroglycan 1.	Laminin subunit alpha 1.	0.922
DLL4	JAG1	ENSMODP00000041583	ENSMODP00000028532	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.447
ENSMODP00000048395	HBEGF	ENSMODP00000048395	ENSMODP00000014655	Link domain-containing protein.	Heparin binding EGF like growth factor.	0.723
ENSMODP00000057968	HOXB2	ENSMODP00000057968	ENSMODP00000015467	Homeobox B4.	Homeobox B2.	0.402
FLNA	AJUBA	ENSMODP00000044463	ENSMODP00000041500	Filamin A.	Ajuba LIM protein.	0.422
FLNA	TOR1A	ENSMODP00000044463	ENSMODP00000008430	Filamin A.	Torsin.	0.403
HBEGF	ADAM17	ENSMODP00000014655	ENSMODP00000018410	Heparin binding EGF like growth factor.	ADAM metallopeptidase domain 17.	0.438
HBEGF	ENSMODP00000048395	ENSMODP00000014655	ENSMODP00000048395	Heparin binding EGF like growth factor.	Link domain-containing protein.	0.723
HOXB2	ENSMODP00000057968	ENSMODP00000015467	ENSMODP00000057968	Homeobox B2.	Homeobox B4.	0.402
JAG1	DLL4	ENSMODP00000028532	ENSMODP00000041583	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.447
LAMA1	DAG1	ENSMODP00000042084	ENSMODP00000048755	Laminin subunit alpha 1.	Dystroglycan 1.	0.922
MRTFA	SRF	ENSMODP00000055885	ENSMODP00000023686	SAP domain-containing protein.	Serum response factor.	0.944
SRF	MRTFA	ENSMODP00000023686	ENSMODP00000055885	Serum response factor.	SAP domain-containing protein.	0.944
TOR1A	FLNA	ENSMODP00000008430	ENSMODP00000044463	Torsin.	Filamin A.	0.403