STRINGSTRING
IFN7 IFN7 FERMT2 FERMT2 CCDC88A CCDC88A SH2B3 SH2B3 BABAM2 BABAM2 IL7 IL7 ENSMODP00000050260 ENSMODP00000050260 CXCL13 CXCL13 LOC103102395 LOC103102395 FEM1B FEM1B IL2 IL2 CCL27 CCL27 DAB2IP DAB2IP FRS2 FRS2 ENSMODP00000053990 ENSMODP00000053990 TRIM37 TRIM37 CTF1 CTF1 SMAD7 SMAD7 EPO EPO IFN4 IFN4 SYK SYK TRIP6 TRIP6 LOC100018815 LOC100018815 IL1RAP IL1RAP RNF41 RNF41 RASL11B RASL11B SDCBP SDCBP CNTF CNTF CXCL11 CXCL11 CNIH4 CNIH4 TGFBR3 TGFBR3 SOCS2 SOCS2 LOC103101367 LOC103101367 VEGFB VEGFB CD2AP CD2AP TOLLIP TOLLIP FADD FADD NTF3 NTF3 CXCL16 CXCL16 PLCG1 PLCG1 PIBF1 PIBF1 LRG1 LRG1 JAK1 JAK1 IL6 IL6 PDCL3 PDCL3 F7BBC6_MONDO F7BBC6_MONDO F6VJC7_MONDO F6VJC7_MONDO F6V029_MONDO F6V029_MONDO TGFBRAP1 TGFBRAP1 TRAF5 TRAF5 ITCH ITCH LOC100018887 LOC100018887 CRLF1 CRLF1 IFN3 IFN3 LOC100021419 LOC100021419 VEGFC VEGFC TGFB2 TGFB2 IFNK IFNK EDA EDA AMH AMH NGF NGF TNFSF13B TNFSF13B ENG ENG TGFB3 TGFB3 TYK2 TYK2 LOC100025872 LOC100025872 NOL3 NOL3 CD300LF CD300LF MSMP MSMP TNFSF12 TNFSF12 GRB2 GRB2 CCL21 CCL21 RIPK1 RIPK1 TGFB1 TGFB1 LIF LIF SMAD2 SMAD2 SMAD6 SMAD6 GH1 GH1 CXCL12 CXCL12 CX3CR1 CX3CR1 ITGB3 ITGB3 PRL PRL IL12A IL12A CCRL2 CCRL2 IL13RA1 IL13RA1 STAT1 STAT1 TGFBR1 TGFBR1 CSF3 CSF3 TRAF3 TRAF3 CX3CL1 CX3CL1 TIMM50 TIMM50 SIVA1 SIVA1 NTF4 NTF4 IL1RN IL1RN IL1F10 IL1F10 IL36RN IL36RN IL36A IL36A LOC100026042 LOC100026042 IL1B IL1B IL1A IL1A IL5 IL5 USP15 USP15 IL34 IL34 CXCL14 CXCL14 ADAM17 ADAM17 TNFSF11 TNFSF11 TGFBR2 TGFBR2 JAK2 JAK2 TMBIM1 TMBIM1 IL27 IL27 LTB LTB TNF TNF LTA LTA GATA3 GATA3 F7FVH6_MONDO F7FVH6_MONDO VEGFD VEGFD TRAF2 TRAF2 S100A14 S100A14 IRAK4 IRAK4 IL17F IL17F F7C7H2_MONDO F7C7H2_MONDO VEGFA VEGFA CCL5 CCL5 LOC103093665 LOC103093665 CXCL8 CXCL8 LOC100618318 LOC100618318 LOC100023783 LOC100023783 TRAF4 TRAF4 IL6ST IL6ST TNFSF8 TNFSF8 PIK3R1 PIK3R1 TRAF6 TRAF6 ERAP1 ERAP1 OSMR OSMR LIFR LIFR PDCL2 PDCL2 STAP1 STAP1 CADM4 CADM4 TFF2 TFF2 CDH5 CDH5 F7C3T6_MONDO F7C3T6_MONDO CSF1 CSF1 TRAF1 TRAF1 JAK3 JAK3 TNFSF14 TNFSF14 EBI3 EBI3 SPRED1 SPRED1 GREM1 GREM1 EDARADD EDARADD TLR5 TLR5 LOC100021258 LOC100021258 PYCARD PYCARD F7AQZ1_MONDO F7AQZ1_MONDO CCL19 CCL19 TNFSF13 TNFSF13 LOC100017283 LOC100017283 LOC100017328 LOC100017328 CXCL9 CXCL9 CCL25 CCL25 CCL20 CCL20 LOC103096620 LOC103096620 IL9 IL9 TGFBR3L TGFBR3L EFNA5 EFNA5 OSM OSM IL15 IL15 ENSMODP00000042114 ENSMODP00000042114 CCL28 CCL28 ENSMODP00000043366 ENSMODP00000043366 CCL22 CCL22 SPRED2 SPRED2 ENSMODP00000044418 ENSMODP00000044418 KITLG KITLG BDNF BDNF NARS1 NARS1 ENSMODP00000047778 ENSMODP00000047778 LOC100021456 LOC100021456 SMAD3 SMAD3 CD40LG CD40LG PGF PGF
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IFN7Type I interferon 7. (183 aa)
FERMT2Fermitin family member 2. (719 aa)
CCDC88ACoiled-coil domain containing 88A. (1829 aa)
SH2B3SH2 domain-containing protein. (458 aa)
BABAM2BRISC and BRCA1 A complex member 2. (407 aa)
IL7Uncharacterized protein. (205 aa)
ENSMODP00000050260C-C motif chemokine. (121 aa)
CXCL13SCY domain-containing protein. (111 aa)
LOC103102395Uncharacterized protein. (207 aa)
FEM1BUncharacterized protein. (627 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (142 aa)
CCL27SCY domain-containing protein. (128 aa)
DAB2IPDAB2 interacting protein. (1180 aa)
FRS2IRS-type PTB domain-containing protein. (508 aa)
ENSMODP00000053990Interleukin-1. (153 aa)
TRIM37Tripartite motif containing 37. (1037 aa)
CTF1Cardiotrophin 1. (220 aa)
SMAD7Mothers against decapentaplegic homolog. (459 aa)
EPOErythropoietin. (188 aa)
IFN4Type I interferon 4. (183 aa)
SYKTyrosine-protein kinase. (588 aa)
TRIP6Thyroid hormone receptor interactor 6. (497 aa)
LOC100018815MARVEL domain-containing protein. (186 aa)
IL1RAPInterleukin 1 receptor accessory protein. (647 aa)
RNF41RING-type domain-containing protein. (201 aa)
RASL11BUncharacterized protein. (254 aa)
SDCBPSyndecan binding protein. (311 aa)
CNTFCiliary neurotrophic factor. (201 aa)
CXCL11C-X-C motif chemokine ligand 11. (87 aa)
CNIH4Uncharacterized protein. (220 aa)
TGFBR3Transforming growth factor beta receptor 3. (835 aa)
SOCS2Suppressor of cytokine signaling 2. (234 aa)
LOC103101367Uncharacterized protein. (211 aa)
VEGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (568 aa)
CD2APCD2 associated protein. (733 aa)
TOLLIPCUE domain-containing protein. (274 aa)
FADDUncharacterized protein. (193 aa)
NTF3Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (343 aa)
CXCL16Uncharacterized protein. (279 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1292 aa)
PIBF1Progesterone immunomodulatory binding factor 1. (794 aa)
LRG1Uncharacterized protein. (356 aa)
JAK1Protein kinase domain-containing protein. (199 aa)
IL6Uncharacterized protein. (220 aa)
PDCL3Phosducin like 3. (251 aa)
F7BBC6_MONDOPhosducin domain-containing protein. (220 aa)
F6VJC7_MONDOTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (258 aa)
F6V029_MONDOTNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (235 aa)
TGFBRAP1Transforming growth factor beta receptor associated protein 1. (860 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (560 aa)
ITCHE3 ubiquitin-protein ligase. (901 aa)
LOC100018887SCY domain-containing protein. (120 aa)
CRLF1Cytokine receptor like factor 1. (403 aa)
IFN3Uncharacterized protein. (184 aa)
LOC100021419Type I interferon 5. (184 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (351 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
IFNKType I interferon 9. (202 aa)
EDAEctodysplasin A; Belongs to the tumor necrosis factor family. (426 aa)
AMHTGF_BETA_2 domain-containing protein. (607 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (238 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (286 aa)
ENGZP domain-containing protein. (654 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
TYK2Tyrosine-protein kinase. (1193 aa)
LOC100025872Left-right determination factor. (368 aa)
NOL3CARD domain-containing protein. (279 aa)
CD300LFIg-like domain-containing protein. (308 aa)
MSMPBeta-microseminoprotein. (138 aa)
TNFSF12TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (291 aa)
GRB2Growth factor receptor bound protein 2. (217 aa)
CCL21C-C motif chemokine ligand 21. (138 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (706 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
SMAD6Mothers against decapentaplegic homolog. (503 aa)
GH1Somatotropin; Plays an important role in growth control. Its major role in stimulating body growth is to stimulate the liver and other tissues to secrete IGF-1. It stimulates both the differentiation and proliferation of myoblasts. It also stimulates amino acid uptake and protein synthesis in muscle and other tissues (By similarity); Belongs to the somatotropin/prolactin family. (215 aa)
CXCL12SCY domain-containing protein; Belongs to the intercrine alpha (chemokine CxC) family. (89 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
PRLProlactin; Prolactin acts primarily on the mammary gland by promoting lactation. (228 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa)
CCRL2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (338 aa)
IL13RA1Interleukin 13 receptor subunit alpha 1. (423 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
CSF3Colony stimulating factor 3. (233 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
CX3CL1SCY domain-containing protein. (409 aa)
TIMM50Mitochondrial import inner membrane translocase subunit TIM50; Essential component of the TIM23 complex, a complex that mediates the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. (369 aa)
SIVA1Apoptosis regulatory protein Siva; Induces CD27-mediated apoptosis. Inhibits BCL2L1 isoform Bcl- x(L) anti-apoptotic activity. Inhibits activation of NF-kappa-B and promotes T-cell receptor-mediated apoptosis. (178 aa)
NTF4Neurotrophin 4; Belongs to the NGF-beta family. (249 aa)
IL1RNInterleukin-1. (174 aa)
IL1F10Interleukin-1. (141 aa)
IL36RNInterleukin-1. (143 aa)
IL36AInterleukin-1. (157 aa)
LOC100026042Interleukin-1. (152 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
IL1AInterleukin-1. (263 aa)
IL5Interleukin-5; Factor that induces terminal differentiation of late- developing B-cells to immunoglobulin secreting cells. (137 aa)
USP15Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (983 aa)
IL34Uncharacterized protein. (279 aa)
CXCL14C-X-C motif chemokine ligand 14. (99 aa)
ADAM17ADAM metallopeptidase domain 17. (747 aa)
TNFSF11Tumor necrosis factor ligand superfamily member. (317 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (564 aa)
JAK2Tyrosine-protein kinase. (1130 aa)
TMBIM1Transmembrane BAX inhibitor motif containing 1; Belongs to the BI1 family. (299 aa)
IL27Uncharacterized protein. (245 aa)
LTBLymphotoxin beta; Belongs to the tumor necrosis factor family. (251 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (229 aa)
LTALymphotoxin alpha; Belongs to the tumor necrosis factor family. (231 aa)
GATA3GATA binding protein 3. (444 aa)
F7FVH6_MONDOIF rod domain-containing protein; Belongs to the intermediate filament family. (1603 aa)
VEGFDVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (353 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (633 aa)
S100A14S100 calcium binding protein A14; Belongs to the S-100 family. (104 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (458 aa)
IL17FUncharacterized protein. (161 aa)
F7C7H2_MONDOInterleukin; Belongs to the IL-15/IL-21 family. (158 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (445 aa)
CCL5C-C motif chemokine ligand 5. (91 aa)
LOC103093665C-C motif chemokine. (226 aa)
CXCL8Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (101 aa)
LOC100618318C-X-C motif chemokine. (110 aa)
LOC100023783C-X-C motif chemokine. (130 aa)
TRAF4TNF receptor-associated factor. (470 aa)
IL6STInterleukin 6 signal transducer. (923 aa)
TNFSF8TNF superfamily member 8; Belongs to the tumor necrosis factor family. (235 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
ERAP1Aminopeptidase. (963 aa)
OSMRUncharacterized protein. (908 aa)
LIFRLIF receptor subunit alpha. (1101 aa)
PDCL2Phosducin domain-containing protein. (244 aa)
STAP1Signal transducing adaptor family member 1. (338 aa)
CADM4Cell adhesion molecule 4. (366 aa)
TFF2Trefoil factor 2. (129 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (722 aa)
F7C3T6_MONDOUncharacterized protein. (506 aa)
CSF1Uncharacterized protein. (340 aa)
TRAF1TNF receptor-associated factor. (380 aa)
JAK3Tyrosine-protein kinase. (1097 aa)
TNFSF14TNF superfamily member 14; Belongs to the tumor necrosis factor family. (227 aa)
EBI3Fibronectin type-III domain-containing protein. (242 aa)
SPRED1Sprouty related EVH1 domain containing 1. (448 aa)
GREM1Gremlin. (184 aa)
EDARADDDeath domain-containing protein. (290 aa)
TLR5Toll like receptor 5; Belongs to the Toll-like receptor family. (861 aa)
LOC100021258Type I interferon 1. (198 aa)
PYCARDPYD and CARD domain containing. (195 aa)
F7AQZ1_MONDOSCY domain-containing protein. (144 aa)
CCL19C-C motif chemokine. (96 aa)
TNFSF13TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (249 aa)
LOC100017283C-C motif chemokine. (91 aa)
LOC100017328C-C motif chemokine. (95 aa)
CXCL9C-X-C motif chemokine. (123 aa)
CCL25SCY domain-containing protein. (138 aa)
CCL20C-C motif chemokine. (102 aa)
LOC103096620SCY domain-containing protein. (103 aa)
IL9Uncharacterized protein. (167 aa)
TGFBR3LZP domain-containing protein. (251 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
OSMUncharacterized protein. (206 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (183 aa)
ENSMODP00000042114SCY domain-containing protein. (97 aa)
CCL28SCY domain-containing protein. (172 aa)
ENSMODP00000043366Uncharacterized protein. (68 aa)
CCL22SCY domain-containing protein. (80 aa)
SPRED2Sprouty related EVH1 domain containing 2. (419 aa)
ENSMODP00000044418Uncharacterized protein. (176 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (285 aa)
NARS1Asparaginyl-tRNA synthetase. (567 aa)
ENSMODP00000047778DUSP domain-containing protein. (224 aa)
LOC100021456C-C motif chemokine. (204 aa)
SMAD3Mothers against decapentaplegic homolog. (426 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (251 aa)
PGFPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (207 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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