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IREB2 IREB2 IDH3A IDH3A SUCLA2 SUCLA2 IDH3G IDH3G FH FH DLST DLST SUCLG2 SUCLG2 PDHB PDHB SDHA SDHA LOC103097953 LOC103097953 ENSMODP00000049451 ENSMODP00000049451 IDH3B IDH3B MDH1 MDH1 SDHB SDHB SDHD SDHD ACO1 ACO1 ENSMODP00000059993 ENSMODP00000059993 PDHA1 PDHA1 SDHC SDHC DLAT DLAT OGDHL OGDHL SUCLG1 SUCLG1 MRPS36 MRPS36 IDH2 IDH2 DHTKD1 DHTKD1 ACO2 ACO2 OGDH OGDH MDH1B MDH1B IDH1 IDH1 MDH2 MDH2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IREB2Aconitase domain-containing protein. (282 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
SUCLA2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (464 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (538 aa)
FHFumarate hydratase. (504 aa)
DLSTDihydrolipoamide S-succinyltransferase. (456 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (541 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (371 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (665 aa)
LOC103097953Uncharacterized protein. (705 aa)
ENSMODP00000049451E1_dh domain-containing protein. (101 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (376 aa)
MDH1Malate dehydrogenase. (356 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (292 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (173 aa)
ACO1Aconitase 1; Belongs to the aconitase/IPM isomerase family. (914 aa)
ENSMODP00000059993Uncharacterized protein. (70 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (411 aa)
SDHCSuccinate dehydrogenase complex subunit C. (217 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (643 aa)
OGDHLOxoglutarate dehydrogenase like. (800 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (371 aa)
MRPS36Mitochondrial ribosomal protein S36. (102 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (455 aa)
DHTKD1Dehydrogenase E1 and transketolase domain containing 1. (923 aa)
ACO2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (782 aa)
OGDHOxoglutarate dehydrogenase. (1020 aa)
MDH1BUncharacterized protein. (432 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
MDH2Malate dehydrogenase. (338 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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