STRINGSTRING
NR1H4 NR1H4 CYP7A1 CYP7A1 PODN PODN HSD17B10 HSD17B10 ABCD3 ABCD3 ARV1 ARV1 CYP27A1 CYP27A1 AMACR AMACR HNF1A HNF1A NPC1 NPC1 ABCB11 ABCB11 K7DZY9_MONDO K7DZY9_MONDO CYP7B1 CYP7B1 CYP39A1 CYP39A1 ENSMODP00000047550 ENSMODP00000047550 LEP LEP ACAA1 ACAA1 SCP2 SCP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
NR1H4Nuclear receptor subfamily 1 group H member 4. (481 aa)
CYP7A1Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (505 aa)
PODNPodocan. (634 aa)
HSD17B10Hydroxysteroid 17-beta dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (293 aa)
ABCD3ATP binding cassette subfamily D member 3. (668 aa)
ARV1Uncharacterized protein. (322 aa)
CYP27A1Cytochrome P450 family 27 subfamily A member 1; Belongs to the cytochrome P450 family. (543 aa)
AMACRAlpha-methylacyl-CoA racemase. (391 aa)
HNF1AHNF1 homeobox A. (613 aa)
NPC1NPC intracellular cholesterol transporter 1. (1281 aa)
ABCB11ATP binding cassette subfamily B member 11. (1322 aa)
K7DZY9_MONDOUncharacterized protein. (531 aa)
CYP7B1Uncharacterized protein; Belongs to the cytochrome P450 family. (462 aa)
CYP39A1Cytochrome P450 family 39 subfamily A member 1; Belongs to the cytochrome P450 family. (469 aa)
ENSMODP00000047550Uncharacterized protein. (226 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
ACAA1Acetyl-CoA acyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (431 aa)
SCP2Sterol carrier protein 2; Belongs to the thiolase-like superfamily. Thiolase family. (552 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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