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| | DGKQ | Diacylglycerol kinase. (972 aa) |
| | H9H7J4_MONDO | Uncharacterized protein. (1180 aa) |
| | H9H7J2_MONDO | ANK_REP_REGION domain-containing protein. (859 aa) |
| | EIF6 | Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. Behaves as a stimulatory translation initiation factor downstream insulin/growth factors. Is also involved in ribosome biogenesis. Associates with pre-60S subunits in the nucleus and is involved in its nuclear export. Cytoplasmic release of TIF6 from 60S subunits and nuclear relocalization is promoted by a RACK1 (RACK1)- dependent protein kinase C activity. In tissues responsive to insulin, contro [...] (245 aa) |
| | ELOVL5 | Elongation of very long chain fatty acids protein 5; Catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle. Condensing enzyme that acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA. May participate to the production of monounsaturated and of polyunsaturated VLCFAs of different chain lengths that are involv [...] (295 aa) |
| | ABCD2 | ATP binding cassette subfamily D member 2. (740 aa) |
| | COQ3 | Ubiquinone biosynthesis O-methyltransferase, mitochondrial; O-methyltransferase that catalyzes the 2 O-methylation steps in the ubiquinone biosynthetic pathway; Belongs to the class I-like SAM-binding methyltransferase superfamily. UbiG/COQ3 family. (354 aa) |
| | MFSD2A | Major facilitator superfamily domain containing 2A. (504 aa) |
| | SIRT1 | Deacetylase sirtuin-type domain-containing protein. (713 aa) |
| | CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) |
| | CLN3 | Battenin. (442 aa) |
| | BRCA1 | Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1840 aa) |
| | MLYCD | Malonyl-CoA decarboxylase. (547 aa) |
| | SCAP | SREBF chaperone. (1287 aa) |
| | IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa) |
| | APOA4 | Uncharacterized protein. (371 aa) |
| | PPARD | Peroxisome proliferator activated receptor delta. (441 aa) |
| | ADIPOQ | Adiponectin, C1Q and collagen domain containing. (256 aa) |
| | NR1D1 | Nuclear receptor subfamily 1 group D member 1. (622 aa) |
| | LONP2 | Lon protease homolog 2, peroxisomal; ATP-dependent serine protease that mediates the selective degradation of misfolded and unassembled polypeptides in the peroxisomal matrix. Necessary for type 2 peroxisome targeting signal (PTS2)-containing protein processing and facilitates peroxisome matrix protein import. May indirectly regulate peroxisomal fatty acid beta- oxidation through degradation of the self-processed forms of TYSND1. (765 aa) |
| | ETFBKMT | Uncharacterized protein. (266 aa) |
| | NR4A3 | Nuclear receptor subfamily 4 group A member 3. (623 aa) |
| | TYSND1 | Serine protease; Belongs to the peptidase S1B family. (561 aa) |
| | PDK2 | Protein-serine/threonine kinase. (407 aa) |
| | PTGS2 | Prostaglandin-endoperoxide synthase 2. (608 aa) |
| | STAR | Steroidogenic acute regulatory protein, mitochondrial; Plays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone. (338 aa) |
| | ERLIN1 | PHB domain-containing protein. (378 aa) |
| | SIRT5 | NAD-dependent protein deacylase sirtuin-5, mitochondrial; NAD-dependent lysine demalonylase, desuccinylase and deglutarylase that specifically removes malonyl, succinyl and glutaryl groups on target proteins. Activates CPS1 and contributes to the regulation of blood ammonia levels during prolonged fasting: acts by mediating desuccinylation and deglutarylation of CPS1, thereby increasing CPS1 activity in response to elevated NAD levels during fasting. Activates SOD1 by mediating its desuccinylation, leading to reduced reactive oxygen species. Activates SHMT2 by mediating its desuccinyla [...] (315 aa) |
| | BMP6 | Bone morphogenetic protein 6. (534 aa) |
| | PLA2G3 | Uncharacterized protein. (688 aa) |
| | MALRD1 | MAM and LDL receptor class A domain containing 1. (2125 aa) |
| | PDK1 | Protein-serine/threonine kinase. (427 aa) |
| | CYP7A1 | Cholesterol 7-alpha-monooxygenase; Belongs to the cytochrome P450 family. (505 aa) |
| | ABCD1 | ATP binding cassette subfamily D member 1. (776 aa) |
| | ABCB11 | ATP binding cassette subfamily B member 11. (1322 aa) |
| | PDK3 | Protein-serine/threonine kinase. (415 aa) |
| | PPARA | Peroxisome proliferator activated receptor alpha. (468 aa) |
| | RDH10 | Retinol dehydrogenase 10; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (341 aa) |
| | FH | Fumarate hydratase. (504 aa) |
| | FABP5 | Fatty acid binding protein 5; Belongs to the calycin superfamily. Fatty-acid binding protein (FABP) family. (135 aa) |
| | ACADVL | Acyl-CoA dehydrogenase very long chain. (817 aa) |
| | PPARG | Peroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (486 aa) |
| | FGF19 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa) |
| | LOC100020223 | Dimethylaniline monooxygenase [N-oxide-forming]. (558 aa) |
| | LOC100020188 | Dimethylaniline monooxygenase [N-oxide-forming]. (565 aa) |
| | F7EWE6_MONDO | Flavin-containing monooxygenase. (122 aa) |
| | FMO2 | Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa) |
| | LOC100020127 | Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa) |
| | FMO3 | Dimethylaniline monooxygenase [N-oxide-forming]. (532 aa) |
| | PROX1 | Prospero homeobox 1. (782 aa) |
| | ANXA1 | Annexin. (346 aa) |
| | APPL2 | Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (663 aa) |
| | SLC45A3 | Solute carrier family 45 member 3. (552 aa) |
| | ATP2B4 | Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1058 aa) |
| | PIBF1 | Progesterone immunomodulatory binding factor 1. (794 aa) |
| | ATCAY | ATCAY kinesin light chain interacting caytaxin. (371 aa) |
| | INSIG1 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa) |
| | SLC7A11 | Uncharacterized protein. (264 aa) |
| | NCOR1 | Nuclear receptor corepressor 1. (2417 aa) |
| | CLCN2 | Chloride voltage-gated channel 2. (964 aa) |
| | STARD4 | START domain-containing protein. (207 aa) |
| | APOC2 | Uncharacterized protein. (235 aa) |
| | LPGAT1 | Lysophosphatidylglycerol acyltransferase 1. (384 aa) |
| | PPTC7 | Protein phosphatase; Belongs to the PP2C family. (304 aa) |
| | ENSMODP00000044573 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) |
| | NCOR2 | Nuclear receptor corepressor 2. (1970 aa) |
| | TRIB3 | Protein kinase domain-containing protein. (146 aa) |
| | FGFR4 | Fibroblast growth factor receptor. (849 aa) |
| | INSIG2 | Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa) |
| | K7E575_MONDO | Uncharacterized protein. (341 aa) |
| | CD74 | CD74 molecule. (281 aa) |
| | GIP | GLUCAGON domain-containing protein. (144 aa) |
| | K7E4A5_MONDO | ANK_REP_REGION domain-containing protein. (589 aa) |
| | K7E0Z8_MONDO | Protein-serine/threonine kinase. (267 aa) |
| | SREBF1 | Sterol regulatory element binding transcription factor 1. (984 aa) |
| | MID1IP1 | MID1 interacting protein 1. (173 aa) |
| | DKK3 | Dickkopf WNT signaling pathway inhibitor 3. (371 aa) |
| | NR1H3 | Nuclear receptor subfamily 1 group H member 3. (442 aa) |
| | PRMT3 | Protein arginine methyltransferase 3; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (541 aa) |
| | DAB2 | DAB adaptor protein 2. (772 aa) |
| | ENSMODP00000052120 | Uncharacterized protein. (56 aa) |
| | DKKL1 | Uncharacterized protein. (114 aa) |
| | H6PD | Hexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (802 aa) |
| | ERLIN2 | Pyridoxal phosphate homeostasis protein; Pyridoxal 5'-phosphate (PLP)-binding protein, which may be involved in intracellular homeostatic regulation of pyridoxal 5'- phosphate (PLP), the active form of vitamin B6. (515 aa) |
| | ENSMODP00000054035 | Uncharacterized protein. (83 aa) |
| | MLXIPL | Uncharacterized protein. (260 aa) |
| | ENSMODP00000055083 | Uncharacterized protein. (59 aa) |
| | ENSMODP00000056404 | Uncharacterized protein. (59 aa) |
| | FMO1 | Flavin-containing monooxygenase. (321 aa) |
| | APOA5 | Apolipoprotein A5. (370 aa) |
| | WNT4 | Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa) |
| | REST | RE1 silencing transcription factor. (973 aa) |
| | PARK7 | DJ-1_PfpI domain-containing protein. (189 aa) |
| | ENSMODP00000058342 | DUF3496 domain-containing protein. (525 aa) |
| | PDK4 | Protein-serine/threonine kinase. (423 aa) |
| | WDTC1 | WD and tetratricopeptide repeats 1. (740 aa) |
| | EGR1 | Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (527 aa) |
| | NR1H4 | Nuclear receptor subfamily 1 group H member 4. (481 aa) |
