STRINGSTRING
TGFB1I1 TGFB1I1 TBX20 TBX20 LRG1 LRG1 F6YRI3_MONDO F6YRI3_MONDO SFRP2 SFRP2 IL6 IL6 GLIPR2 GLIPR2 SDHAF2-2 SDHAF2-2 ENSMODP00000051147 ENSMODP00000051147 DAB2 DAB2 SPRY1 SPRY1 TCF7L2 TCF7L2 DAB2IP DAB2IP BCL9L BCL9L SMAD7 SMAD7 BAMBI BAMBI CLASP1 CLASP1 SDCBP SDCBP MTOR MTOR RGCC RGCC TGFB3 TGFB3 F7F0M1_MONDO F7F0M1_MONDO FOXA2 FOXA2 ZNF750 ZNF750 TGFB1 TGFB1 SMAD2 SMAD2 ZNF703 ZNF703 MAD2L2 MAD2L2 F7BA89_MONDO F7BA89_MONDO CTNNB1 CTNNB1 FOXA1 FOXA1 IL17RD IL17RD TGFBR1 TGFBR1 BMP4 BMP4 OLFM1 OLFM1 HPN HPN IL1B IL1B TGFBR2 TGFBR2 GATA3 GATA3 TRIM62 TRIM62 ELL3 ELL3 USF3 USF3 CRB2 CRB2 SDHAF2 SDHAF2 LEF1 LEF1 LOXL2 LOXL2 JAG1 JAG1 SPRED1 SPRED1 GREM1 GREM1 EZH2 EZH2 LOXL3 LOXL3 SMAD4 SMAD4 K7E0A4_MONDO K7E0A4_MONDO ENSMODP00000042313 ENSMODP00000042313 PHLDB2 PHLDB2 POFUT2 POFUT2 PHLDB1 PHLDB1 SPRED2 SPRED2 ACVR1 ACVR1 ENG ENG MCRIP1 MCRIP1 ENSMODP00000047919 ENSMODP00000047919 SMAD3 SMAD3 FERMT2 FERMT2 DAG1 DAG1 EFNA1 EFNA1 TGFB2 TGFB2 AXIN2 AXIN2 BMP2 BMP2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (442 aa)
TBX20T-box transcription factor 20. (456 aa)
LRG1Uncharacterized protein. (356 aa)
F6YRI3_MONDOUncharacterized protein. (647 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
IL6Uncharacterized protein. (220 aa)
GLIPR2SCP domain-containing protein; Belongs to the CRISP family. (428 aa)
SDHAF2-2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (152 aa)
ENSMODP00000051147Uncharacterized protein. (107 aa)
DAB2DAB adaptor protein 2. (772 aa)
SPRY1Uncharacterized protein. (105 aa)
TCF7L2Transcription factor 7 like 2. (579 aa)
DAB2IPDAB2 interacting protein. (1180 aa)
BCL9LBCL9 like. (1363 aa)
SMAD7Mothers against decapentaplegic homolog. (459 aa)
BAMBIBMP and activin membrane bound inhibitor. (268 aa)
CLASP1Cytoplasmic linker associated protein 1. (1552 aa)
SDCBPSyndecan binding protein. (311 aa)
MTORSerine/threonine-protein kinase mTOR. (1040 aa)
RGCCRegulator of cell cycle. (183 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
F7F0M1_MONDOMH2 domain-containing protein. (347 aa)
FOXA2Forkhead box A2. (459 aa)
ZNF750Zinc finger protein 750. (713 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
ZNF703Zinc finger protein 703. (601 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (223 aa)
F7BA89_MONDOUncharacterized protein; Belongs to the PI3/PI4-kinase family. (740 aa)
CTNNB1Catenin beta 1. (781 aa)
FOXA1Forkhead box A1. (440 aa)
IL17RDInterleukin 17 receptor D. (704 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
BMP4Bone morphogenetic protein 4. (410 aa)
OLFM1Olfactomedin 1. (485 aa)
HPNHepsin; Belongs to the peptidase S1 family. (411 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (564 aa)
GATA3GATA binding protein 3. (444 aa)
TRIM62Uncharacterized protein. (441 aa)
ELL3Elongation factor for RNA polymerase II 3. (385 aa)
USF3Upstream transcription factor family member 3. (2233 aa)
CRB2Uncharacterized protein. (1430 aa)
SDHAF2Succinate dehydrogenase assembly factor 2, mitochondrial; Plays an essential role in the assembly of succinate dehydrogenase (SDH), an enzyme complex (also referred to as respiratory complex II) that is a component of both the tricarboxylic acid (TCA) cycle and the mitochondrial electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SDHA of the SDH catalytic dimer. (158 aa)
LEF1Lymphoid enhancer binding factor 1. (401 aa)
LOXL2Lysyl oxidase like 2. (713 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1276 aa)
SPRED1Sprouty related EVH1 domain containing 1. (448 aa)
GREM1Gremlin. (184 aa)
EZH2Uncharacterized protein. (665 aa)
LOXL3Lysyl oxidase like 3. (756 aa)
SMAD4Mothers against decapentaplegic homolog. (534 aa)
K7E0A4_MONDOUncharacterized protein. (667 aa)
ENSMODP00000042313Uncharacterized protein. (84 aa)
PHLDB2Pleckstrin homology like domain family B member 2. (1317 aa)
POFUT2Protein O-fucosyltransferase 2. (510 aa)
PHLDB1Pleckstrin homology like domain family B member 1. (1546 aa)
SPRED2Sprouty related EVH1 domain containing 2. (419 aa)
ACVR1TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (559 aa)
ENGZP domain-containing protein. (654 aa)
MCRIP1Uncharacterized protein. (227 aa)
ENSMODP00000047919TOG domain-containing protein. (1250 aa)
SMAD3Mothers against decapentaplegic homolog. (426 aa)
FERMT2Fermitin family member 2. (719 aa)
DAG1Dystroglycan 1. (896 aa)
EFNA1Ephrin A1; Belongs to the ephrin family. (267 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
AXIN2Axin 2. (838 aa)
BMP2Bone morphogenetic protein 2. (436 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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