STRINGSTRING
TGFB3 TGFB3 DAB2 DAB2 FERMT2 FERMT2 SMAD3 SMAD3 ACVR1 ACVR1 ENSMODP00000042313 ENSMODP00000042313 K7E0A4_MONDO K7E0A4_MONDO TGFB1I1 TGFB1I1 F7BA89_MONDO F7BA89_MONDO OLFM1 OLFM1 SMAD4 SMAD4 LOXL3 LOXL3 EZH2 EZH2 JAG1 JAG1 LOXL2 LOXL2 LEF1 LEF1 CRB2 CRB2 TGFBR2 TGFBR2 BCL9L BCL9L BAMBI BAMBI ZNF703 ZNF703 SMAD2 SMAD2 TGFB1 TGFB1 F7F0M1_MONDO F7F0M1_MONDO SDCBP SDCBP MTOR MTOR RGCC RGCC TCF7L2 TCF7L2 IL1B IL1B CTNNB1 CTNNB1 TGFBR1 TGFBR1 BMP4 BMP4 TBX20 TBX20 LRG1 LRG1 F6YRI3_MONDO F6YRI3_MONDO IL6 IL6 GLIPR2 GLIPR2 BMP2 BMP2 AXIN2 AXIN2 TGFB2 TGFB2 ENG ENG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
DAB2DAB adaptor protein 2. (772 aa)
FERMT2Fermitin family member 2. (719 aa)
SMAD3Mothers against decapentaplegic homolog. (426 aa)
ACVR1TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (559 aa)
ENSMODP00000042313Uncharacterized protein. (84 aa)
K7E0A4_MONDOUncharacterized protein. (667 aa)
TGFB1I1Transforming growth factor beta-1-induced transcript 1 protein; Functions as a molecular adapter coordinating multiple protein-protein interactions at the focal adhesion complex and in the nucleus. Links various intracellular signaling modules to plasma membrane receptors and regulates the Wnt and TGFB signaling pathways. (442 aa)
F7BA89_MONDOUncharacterized protein; Belongs to the PI3/PI4-kinase family. (740 aa)
OLFM1Olfactomedin 1. (485 aa)
SMAD4Mothers against decapentaplegic homolog. (534 aa)
LOXL3Lysyl oxidase like 3. (756 aa)
EZH2Uncharacterized protein. (665 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1276 aa)
LOXL2Lysyl oxidase like 2. (713 aa)
LEF1Lymphoid enhancer binding factor 1. (401 aa)
CRB2Uncharacterized protein. (1430 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (564 aa)
BCL9LBCL9 like. (1363 aa)
BAMBIBMP and activin membrane bound inhibitor. (268 aa)
ZNF703Zinc finger protein 703. (601 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa)
F7F0M1_MONDOMH2 domain-containing protein. (347 aa)
SDCBPSyndecan binding protein. (311 aa)
MTORSerine/threonine-protein kinase mTOR. (1040 aa)
RGCCRegulator of cell cycle. (183 aa)
TCF7L2Transcription factor 7 like 2. (579 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
CTNNB1Catenin beta 1. (781 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
BMP4Bone morphogenetic protein 4. (410 aa)
TBX20T-box transcription factor 20. (456 aa)
LRG1Uncharacterized protein. (356 aa)
F6YRI3_MONDOUncharacterized protein. (647 aa)
IL6Uncharacterized protein. (220 aa)
GLIPR2SCP domain-containing protein; Belongs to the CRISP family. (428 aa)
BMP2Bone morphogenetic protein 2. (436 aa)
AXIN2Axin 2. (838 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
ENGZP domain-containing protein. (654 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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