STRINGSTRING
SMAD4 SMAD4 TGFB1 TGFB1 BMP6 BMP6 BMP15 BMP15 BMPR1A BMPR1A BMP10 BMP10 NODAL NODAL TGFBR1 TGFBR1 BMP4 BMP4 TGFBR2 TGFBR2 BMPR2 BMPR2 BMP7 BMP7 LOC100031977 LOC100031977 GDF3 GDF3 BMP5 BMP5 ENSMODP00000059845 ENSMODP00000059845 INHBB INHBB GDF6 GDF6 LOC103092471 LOC103092471 SDCBP SDCBP ENSMODP00000056096 ENSMODP00000056096 DAB2 DAB2 CSNK2B CSNK2B INHA INHA ENSMODP00000050842 ENSMODP00000050842 GDF7 GDF7 ENSMODP00000047664 ENSMODP00000047664 GDF2 GDF2 ACVR1 ACVR1 GDF1 GDF1 RBPMS RBPMS F7F0M1_MONDO F7F0M1_MONDO TWSG1 TWSG1 BMP3 BMP3 MILL-like MILL-like GDF5 GDF5 GDF10 GDF10 INHBA INHBA BMP2 BMP2 TGFB2 TGFB2 ENG ENG TGFB3 TGFB3 LOC100025872 LOC100025872 INHBC INHBC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD4Mothers against decapentaplegic homolog. (534 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa)
BMP6Bone morphogenetic protein 6. (534 aa)
BMP15TGF_BETA_2 domain-containing protein. (380 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
BMP10Bone morphogenetic protein 10. (422 aa)
NODALNodal growth differentiation factor. (347 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
BMP4Bone morphogenetic protein 4. (410 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (564 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
BMP7Bone morphogenetic protein 7. (432 aa)
LOC100031977TGF_BETA_2 domain-containing protein. (436 aa)
GDF3Growth differentiation factor 3. (358 aa)
BMP5Bone morphogenetic protein 5. (455 aa)
ENSMODP00000059845Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (200 aa)
INHBBInhibin subunit beta B. (374 aa)
GDF6Growth differentiation factor 6. (505 aa)
LOC103092471TGF_BETA_2 domain-containing protein. (355 aa)
SDCBPSyndecan binding protein. (311 aa)
ENSMODP00000056096Ig-like domain-containing protein; Belongs to the MHC class I family. (376 aa)
DAB2DAB adaptor protein 2. (772 aa)
CSNK2BCasein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (235 aa)
INHATGF_BETA_2 domain-containing protein. (404 aa)
ENSMODP00000050842Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (88 aa)
GDF7TGF_BETA_2 domain-containing protein. (461 aa)
ENSMODP00000047664Casein kinase II subunit beta; Plays a complex role in regulating the basal catalytic activity of the alpha subunit; Belongs to the casein kinase 2 subunit beta family. (102 aa)
GDF2TGF_BETA_2 domain-containing protein. (427 aa)
ACVR1TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (559 aa)
GDF1TGF_BETA_2 domain-containing protein. (387 aa)
RBPMSRRM domain-containing protein. (445 aa)
F7F0M1_MONDOMH2 domain-containing protein. (347 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (222 aa)
BMP3Bone morphogenetic protein 3; Belongs to the TGF-beta family. (448 aa)
MILL-likeMHC class I-like located near the LRC-like; Belongs to the MHC class I family. (343 aa)
GDF5Growth differentiation factor 5. (495 aa)
GDF10Growth differentiation factor 10. (493 aa)
INHBAInhibin subunit beta A. (426 aa)
BMP2Bone morphogenetic protein 2. (436 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
ENGZP domain-containing protein. (654 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
LOC100025872Left-right determination factor. (368 aa)
INHBCInhibin subunit beta C. (361 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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