(13 nodes) Dopamine transport network (Monodelphis domestica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	SLC29A4	Solute carrier family 29 member 4. (528 aa)
	SLC6A3	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (709 aa)
	SLC22A2	Solute carrier family 22 member 2. (554 aa)
	DRD2	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (415 aa)
	F6TDG8_MONDO	Uncharacterized protein. (89 aa)
	PARK2	RBR-type E3 ubiquitin transferase. (74 aa)
	SLC22A1	Solute carrier family 22 member 1. (637 aa)
	SLC22A3	Solute carrier family 22 member 3. (566 aa)
	ENSMODP00000050667	Ubiquitin-like domain-containing protein. (89 aa)
	MAPK15	Mitogen-activated protein kinase. (579 aa)
	PINK1	Protein kinase domain-containing protein. (573 aa)
	SLC6A2	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (607 aa)
	PARK7	DJ-1_PfpI domain-containing protein. (189 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DRD2	SLC6A3	ENSMODP00000017747	ENSMODP00000001627	Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.898
ENSMODP00000050667	PARK7	ENSMODP00000050667	ENSMODP00000057855	Ubiquitin-like domain-containing protein.	DJ-1_PfpI domain-containing protein.	0.767
ENSMODP00000050667	PINK1	ENSMODP00000050667	ENSMODP00000053610	Ubiquitin-like domain-containing protein.	Protein kinase domain-containing protein.	0.896
F6TDG8_MONDO	PARK7	ENSMODP00000029226	ENSMODP00000057855	Uncharacterized protein.	DJ-1_PfpI domain-containing protein.	0.767
F6TDG8_MONDO	PINK1	ENSMODP00000029226	ENSMODP00000053610	Uncharacterized protein.	Protein kinase domain-containing protein.	0.896
PARK2	PARK7	ENSMODP00000039734	ENSMODP00000057855	RBR-type E3 ubiquitin transferase.	DJ-1_PfpI domain-containing protein.	0.905
PARK2	PINK1	ENSMODP00000039734	ENSMODP00000053610	RBR-type E3 ubiquitin transferase.	Protein kinase domain-containing protein.	0.998
PARK2	SLC6A3	ENSMODP00000039734	ENSMODP00000001627	RBR-type E3 ubiquitin transferase.	Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family.	0.440
PARK7	ENSMODP00000050667	ENSMODP00000057855	ENSMODP00000050667	DJ-1_PfpI domain-containing protein.	Ubiquitin-like domain-containing protein.	0.767
PARK7	F6TDG8_MONDO	ENSMODP00000057855	ENSMODP00000029226	DJ-1_PfpI domain-containing protein.	Uncharacterized protein.	0.767
PARK7	PARK2	ENSMODP00000057855	ENSMODP00000039734	DJ-1_PfpI domain-containing protein.	RBR-type E3 ubiquitin transferase.	0.905
PARK7	PINK1	ENSMODP00000057855	ENSMODP00000053610	DJ-1_PfpI domain-containing protein.	Protein kinase domain-containing protein.	0.779
PINK1	ENSMODP00000050667	ENSMODP00000053610	ENSMODP00000050667	Protein kinase domain-containing protein.	Ubiquitin-like domain-containing protein.	0.896
PINK1	F6TDG8_MONDO	ENSMODP00000053610	ENSMODP00000029226	Protein kinase domain-containing protein.	Uncharacterized protein.	0.896
PINK1	PARK2	ENSMODP00000053610	ENSMODP00000039734	Protein kinase domain-containing protein.	RBR-type E3 ubiquitin transferase.	0.998
PINK1	PARK7	ENSMODP00000053610	ENSMODP00000057855	Protein kinase domain-containing protein.	DJ-1_PfpI domain-containing protein.	0.779
SLC22A1	SLC22A2	ENSMODP00000042030	ENSMODP00000008425	Solute carrier family 22 member 1.	Solute carrier family 22 member 2.	0.901
SLC22A1	SLC22A3	ENSMODP00000042030	ENSMODP00000045734	Solute carrier family 22 member 1.	Solute carrier family 22 member 3.	0.907
SLC22A2	SLC22A1	ENSMODP00000008425	ENSMODP00000042030	Solute carrier family 22 member 2.	Solute carrier family 22 member 1.	0.901
SLC22A2	SLC22A3	ENSMODP00000008425	ENSMODP00000045734	Solute carrier family 22 member 2.	Solute carrier family 22 member 3.	0.910