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ENSMODP00000047877 ENSMODP00000047877 RICTOR RICTOR PRKAA1 PRKAA1 F7ES06_MONDO F7ES06_MONDO MAST4 MAST4 CSNK2A1 CSNK2A1 TTBK1 TTBK1 CSNK1E CSNK1E LRRK2 LRRK2 PAK2 PAK2 DYRK4 DYRK4 MAPK1 MAPK1 PRKD1 PRKD1 CDK1 CDK1 F6V3Z4_MONDO F6V3Z4_MONDO CAMK1D CAMK1D LATS1 LATS1 PRKCQ PRKCQ STK38L STK38L PDPK1 PDPK1 PCK1 PCK1 AKT1 AKT1 AURKA AURKA PRKCI PRKCI PKD1 PKD1 PIKFYVE PIKFYVE MAPK3 MAPK3 PBK PBK TGFBR2 TGFBR2 F7E823_MONDO F7E823_MONDO RPS6KA6 RPS6KA6 BAK1 BAK1 TOP1 TOP1 HIPK1 HIPK1 PRKCE PRKCE F7F807_MONDO F7F807_MONDO MAPK7 MAPK7 SGK2 SGK2 MKNK1 MKNK1 IKBKE IKBKE DYRK3 DYRK3 MAPKAPK2 MAPKAPK2 VRK2 VRK2 IL20 IL20 DCLK3 DCLK3 CAMK1G CAMK1G PKN1 PKN1 RPS6KA5 RPS6KA5 MAP3K13 MAP3K13 F6Z6L9_MONDO F6Z6L9_MONDO MAST3 MAST3 TSSK4 TSSK4 PRKAA2 PRKAA2 GAS6 GAS6 PRKCA PRKCA DGKQ DGKQ CSNK1G2 CSNK1G2 MKNK2 MKNK2 CAMK1 CAMK1 BCL2 BCL2 AKT3 AKT3 PLK1 PLK1 RPS6KB1 RPS6KB1 PDK3 PDK3 RPS6KB2 RPS6KB2 AKT2 AKT2 HIPK4 HIPK4 SGK3 SGK3 RPS6KA3 RPS6KA3 PNCK PNCK LATS2 LATS2 CHEK2 CHEK2 MYO3B MYO3B RIPK1 RIPK1 TLK1 TLK1 PRKCH PRKCH ULK3 ULK3 PDGFB PDGFB EIF2AK3 EIF2AK3 HIPK3 HIPK3 STK32A STK32A IKBKB IKBKB TLK2 TLK2 CHUK CHUK CAB39 CAB39 PRKCD PRKCD CSNK1G1 CSNK1G1 ULK2 ULK2 H9H6H3_MONDO H9H6H3_MONDO F7BA89_MONDO F7BA89_MONDO F7GDN3_MONDO F7GDN3_MONDO MAPKAPK3 MAPKAPK3 CDC7 CDC7 MAPKAPK5 MAPKAPK5 TGFBR1 TGFBR1 NEK7 NEK7 MAP4K1 MAP4K1 STK38 STK38 MAPK13 MAPK13 ROCK2 ROCK2 CSNK1A1 CSNK1A1 ENSMODP00000059959 ENSMODP00000059959 ATM ATM GSK3B GSK3B ENSMODP00000059579 ENSMODP00000059579 DYRK1B DYRK1B CDK5 CDK5 MTOR MTOR ENSMODP00000057488 ENSMODP00000057488 PRKDC PRKDC ENSMODP00000056415 ENSMODP00000056415 ROCK1 ROCK1 SYK SYK CSNK1D CSNK1D EPO EPO ENSMODP00000053904 ENSMODP00000053904 MAPK12 MAPK12 PINK1 PINK1 SMG1 SMG1 PRKX PRKX AURKB AURKB NLK NLK ATR ATR ENSMODP00000052394 ENSMODP00000052394 RPS6KA4 RPS6KA4 DCLK1 DCLK1 TTBK2 TTBK2 ENSMODP00000051585 ENSMODP00000051585 ENSMODP00000051258 ENSMODP00000051258 ENSMODP00000049947 ENSMODP00000049947 PKN2 PKN2 TTK TTK BAX BAX SBK1 SBK1 ILK ILK UHMK1 UHMK1 RPS6KA1 RPS6KA1 NEK6 NEK6 STK32C STK32C STK32B STK32B RPS6KA2 RPS6KA2 PRKCB PRKCB MASTL MASTL ENSMODP00000044856 ENSMODP00000044856 WNK1 WNK1 CSNK2A2 CSNK2A2 ENSMODP00000043650 ENSMODP00000043650 ENSMODP00000043620 ENSMODP00000043620 DCLK2 DCLK2 DYRK1A DYRK1A VRK3 VRK3 ENSMODP00000042826 ENSMODP00000042826 CAMKV CAMKV LOC100619142 LOC100619142 PRKCZ PRKCZ TNKS TNKS K7E3Z6_MONDO K7E3Z6_MONDO K7E3T4_MONDO K7E3T4_MONDO K7E2A9_MONDO K7E2A9_MONDO K7E1M2_MONDO K7E1M2_MONDO F6XDH7_MONDO F6XDH7_MONDO F6RLE5_MONDO F6RLE5_MONDO F7EM52_MONDO F7EM52_MONDO F7C1G3_MONDO F7C1G3_MONDO F6TU13_MONDO F6TU13_MONDO F6SGC1_MONDO F6SGC1_MONDO F7AEU9_MONDO F7AEU9_MONDO NTRK2 NTRK2 ULK1 ULK1 VRK1 VRK1 TSSK6 TSSK6 MAPK9 MAPK9 PKN3 PKN3 CLSPN CLSPN LOC100617582 LOC100617582 MORC3 MORC3 PRKG2 PRKG2
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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMODP00000047877Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (382 aa)
RICTORRPTOR independent companion of MTOR complex 2. (1735 aa)
PRKAA1Non-specific serine/threonine protein kinase. (559 aa)
F7ES06_MONDOCalponin-homology (CH) domain-containing protein. (460 aa)
MAST4Microtubule associated serine/threonine kinase family member 4. (2437 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (448 aa)
TTBK1Protein kinase domain-containing protein. (656 aa)
CSNK1EUncharacterized protein. (210 aa)
LRRK2Leucine rich repeat kinase 2. (2527 aa)
PAK2Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (298 aa)
DYRK4Dual specificity tyrosine phosphorylation regulated kinase 4. (689 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (861 aa)
CDK1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa)
F6V3Z4_MONDOProtein kinase domain-containing protein. (284 aa)
CAMK1DCalcium/calmodulin dependent protein kinase ID; Belongs to the protein kinase superfamily. (392 aa)
LATS1Large tumor suppressor kinase 1. (1151 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (695 aa)
STK38LNon-specific serine/threonine protein kinase. (202 aa)
PDPK13-phosphoinositide dependent protein kinase 1; Belongs to the protein kinase superfamily. (455 aa)
PCK1Phosphoenolpyruvate carboxykinase 1. (622 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (480 aa)
AURKAAurora kinase A; Belongs to the protein kinase superfamily. (488 aa)
PRKCIProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (579 aa)
PKD1Polycystin 1, transient receptor potential channel interacting. (4343 aa)
PIKFYVEPhosphoinositide kinase, FYVE-type zinc finger containing. (2090 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
PBKPDZ binding kinase. (346 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (564 aa)
F7E823_MONDOProtein kinase domain-containing protein. (353 aa)
RPS6KA6Ribosomal protein S6 kinase. (771 aa)
BAK1BCL2 antagonist/killer 1. (204 aa)
TOP1DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (782 aa)
HIPK1Homeodomain interacting protein kinase 1. (1211 aa)
PRKCEProtein kinase domain-containing protein. (212 aa)
F7F807_MONDOC2 domain-containing protein. (139 aa)
MAPK7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (778 aa)
SGK2Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (362 aa)
MKNK1MAPK interacting serine/threonine kinase 1; Belongs to the protein kinase superfamily. (423 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (726 aa)
DYRK3Dual specificity tyrosine phosphorylation regulated kinase 3. (588 aa)
MAPKAPK2MAPK activated protein kinase 2. (388 aa)
VRK2Protein kinase domain-containing protein. (393 aa)
IL20Interleukin 20. (176 aa)
DCLK3Protein kinase domain-containing protein. (624 aa)
CAMK1GCalcium/calmodulin dependent protein kinase IG; Belongs to the protein kinase superfamily. (496 aa)
PKN1Protein kinase N1. (956 aa)
RPS6KA5Ribosomal protein S6 kinase. (795 aa)
MAP3K13Mitogen-activated protein kinase kinase kinase. (964 aa)
F6Z6L9_MONDOUncharacterized protein. (1495 aa)
MAST3Uncharacterized protein. (1524 aa)
TSSK4Testis specific serine kinase 4. (351 aa)
PRKAA2Non-specific serine/threonine protein kinase. (551 aa)
GAS6Growth arrest specific 6. (677 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (689 aa)
DGKQDiacylglycerol kinase. (972 aa)
CSNK1G2Casein kinase 1 gamma 2. (510 aa)
MKNK2MAPK interacting serine/threonine kinase 2; Belongs to the protein kinase superfamily. (453 aa)
CAMK1Calcium/calmodulin dependent protein kinase I; Belongs to the protein kinase superfamily. (373 aa)
BCL2BCL2 apoptosis regulator. (188 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
PLK1Serine/threonine-protein kinase PLK. (614 aa)
RPS6KB1Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (523 aa)
PDK3Protein-serine/threonine kinase. (415 aa)
RPS6KB2Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (476 aa)
AKT2AKT serine/threonine kinase 2; Belongs to the protein kinase superfamily. (498 aa)
HIPK4Homeodomain interacting protein kinase 4. (617 aa)
SGK3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (490 aa)
RPS6KA3Ribosomal protein S6 kinase. (740 aa)
PNCKPregnancy up-regulated nonubiquitous CaM kinase; Belongs to the protein kinase superfamily. (340 aa)
LATS2Large tumor suppressor kinase 2. (1123 aa)
CHEK2Checkpoint kinase 2. (531 aa)
MYO3BMyosin IIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1274 aa)
RIPK1Receptor interacting serine/threonine kinase 1. (706 aa)
TLK1Tousled like kinase 1. (774 aa)
PRKCHProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (681 aa)
ULK3Unc-51 like kinase 3. (535 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (235 aa)
EIF2AK3Eukaryotic translation initiation factor 2 alpha kinase 3. (1104 aa)
HIPK3Homeodomain interacting protein kinase 3. (1247 aa)
STK32ASerine/threonine kinase 32A; Belongs to the protein kinase superfamily. (417 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (693 aa)
TLK2Tousled like kinase 2. (750 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
CAB39Calcium binding protein 39. (341 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
CSNK1G1Casein kinase 1 gamma 1; Belongs to the protein kinase superfamily. (467 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1041 aa)
H9H6H3_MONDOUncharacterized protein. (170 aa)
F7BA89_MONDOUncharacterized protein; Belongs to the PI3/PI4-kinase family. (740 aa)
F7GDN3_MONDOProtein kinase domain-containing protein. (317 aa)
MAPKAPK3MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (395 aa)
CDC7Cell division cycle 7. (567 aa)
MAPKAPK5MAPK activated protein kinase 5. (473 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
NEK7NIMA related kinase 7; Belongs to the protein kinase superfamily. (302 aa)
MAP4K1Mitogen-activated protein kinase kinase kinase kinase 1; May play a role in the response to environmental stress. Appears to act upstream of the JUN N-terminal pathway. (820 aa)
STK38Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (465 aa)
MAPK13Mitogen-activated protein kinase. (366 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1482 aa)
CSNK1A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (370 aa)
ENSMODP00000059959AGC-kinase C-terminal domain-containing protein. (64 aa)
ATMTAN domain-containing protein. (112 aa)
GSK3BGlycogen synthase kinase 3 beta; Belongs to the protein kinase superfamily. (444 aa)
ENSMODP00000059579Uncharacterized protein. (66 aa)
DYRK1BDual specificity tyrosine phosphorylation regulated kinase 1B. (728 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
MTORSerine/threonine-protein kinase mTOR. (1040 aa)
ENSMODP00000057488AGC-kinase C-terminal domain-containing protein. (137 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4010 aa)
ENSMODP00000056415Uncharacterized protein. (64 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1322 aa)
SYKTyrosine-protein kinase. (588 aa)
CSNK1DCasein kinase 1 delta. (501 aa)
EPOErythropoietin. (188 aa)
ENSMODP00000053904AGC-kinase C-terminal domain-containing protein. (66 aa)
MAPK12Mitogen-activated protein kinase. (364 aa)
PINK1Protein kinase domain-containing protein. (573 aa)
SMG1SMG1 nonsense mediated mRNA decay associated PI3K related kinase; Belongs to the PI3/PI4-kinase family. (3671 aa)
PRKXUncharacterized protein. (419 aa)
AURKBAurora kinase B; Belongs to the protein kinase superfamily. (467 aa)
NLKMitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (529 aa)
ATRUncharacterized protein. (159 aa)
ENSMODP00000052394Protein kinase domain-containing protein. (279 aa)
RPS6KA4Non-specific serine/threonine protein kinase. (609 aa)
DCLK1Doublecortin like kinase 1. (740 aa)
TTBK2Tau tubulin kinase 2. (1259 aa)
ENSMODP00000051585Protein kinase domain-containing protein. (156 aa)
ENSMODP00000051258CRIB domain-containing protein. (122 aa)
ENSMODP00000049947Ribosomal protein S6 kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. S6 kinase subfamily. (496 aa)
PKN2Protein kinase N2. (1013 aa)
TTKTTK protein kinase. (895 aa)
BAXUncharacterized protein. (296 aa)
SBK1Serine/threonine-protein kinase SBK1; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. (396 aa)
ILKIntegrin linked kinase. (486 aa)
UHMK1Uncharacterized protein. (419 aa)
RPS6KA1Ribosomal protein S6 kinase. (740 aa)
NEK6NIMA related kinase 6; Belongs to the protein kinase superfamily. (417 aa)
STK32CSerine/threonine kinase 32C. (569 aa)
STK32BSerine/threonine kinase 32B. (402 aa)
RPS6KA2Ribosomal protein S6 kinase. (733 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (641 aa)
MASTLMicrotubule associated serine/threonine kinase like. (909 aa)
ENSMODP00000044856Uncharacterized protein. (71 aa)
WNK1WNK lysine deficient protein kinase 1. (2867 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (392 aa)
ENSMODP00000043650Uncharacterized protein. (138 aa)
ENSMODP00000043620Protein kinase domain-containing protein. (291 aa)
DCLK2Uncharacterized protein. (1631 aa)
DYRK1ADual specificity tyrosine phosphorylation regulated kinase 1A. (754 aa)
VRK3Protein kinase domain-containing protein. (524 aa)
ENSMODP00000042826Protein kinase domain-containing protein. (108 aa)
CAMKVCaM kinase like vesicle associated. (499 aa)
LOC100619142Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (394 aa)
PRKCZProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (589 aa)
TNKSPoly [ADP-ribose] polymerase. (1442 aa)
K7E3Z6_MONDOMyosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (187 aa)
K7E3T4_MONDOPhorbol-ester/DAG-type domain-containing protein. (54 aa)
K7E2A9_MONDOMyosin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (91 aa)
K7E1M2_MONDOUncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1138 aa)
F6XDH7_MONDOUncharacterized protein. (165 aa)
F6RLE5_MONDOProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (302 aa)
F7EM52_MONDOUncharacterized protein. (1309 aa)
F7C1G3_MONDOProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (337 aa)
F6TU13_MONDOProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa)
F6SGC1_MONDOProtein kinase domain-containing protein; Belongs to the protein kinase superfamily. (318 aa)
F7AEU9_MONDOProtein kinase domain-containing protein. (192 aa)
NTRK2Tyrosine-protein kinase receptor. (750 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1013 aa)
VRK1VRK serine/threonine kinase 1; Belongs to the protein kinase superfamily. (401 aa)
TSSK6Testis specific serine kinase 6; Belongs to the protein kinase superfamily. (272 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
PKN3Protein kinase N3. (909 aa)
CLSPNClaspin. (1238 aa)
LOC100617582Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1107 aa)
MORC3MORC family CW-type zinc finger 3. (899 aa)
PRKG2cGMP-dependent protein kinase. (759 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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