STRINGSTRING
IL22RA1 IL22RA1 CXCR5 CXCR5 IL10RA IL10RA IL1RN IL1RN IL36RN IL36RN NOG NOG CCR10 CCR10 CER1 CER1 TGFBR2 TGFBR2 LTBP1 LTBP1 LOC100012302 LOC100012302 BMPR2 BMPR2 WFIKKN1 WFIKKN1 UCMA UCMA F6WYG5_MONDO F6WYG5_MONDO IL20RA IL20RA CSF3R CSF3R TNFRSF1A TNFRSF1A IL20RB IL20RB HJV HJV IL17F IL17F FGF2 FGF2 BMPR1B BMPR1B IL31RA IL31RA IL6ST IL6ST OSMR OSMR LIFR LIFR IFNAR1 IFNAR1 TWSG1 TWSG1 ACKR3 ACKR3 ACKR4 ACKR4 CCR3 CCR3 XCR1 XCR1 EBI3 EBI3 TSKU TSKU IL6R IL6R CD4 CD4 KIT KIT IL3RA IL3RA TNFRSF9 TNFRSF9 K7E4W0_MONDO K7E4W0_MONDO CD74 CD74 CRLF2 CRLF2 GREM1 GREM1 LOC103094977 LOC103094977 ENSMODP00000041557 ENSMODP00000041557 ENSMODP00000041663 ENSMODP00000041663 KLHL20 KLHL20 ENSMODP00000043446 ENSMODP00000043446 ACVR1 ACVR1 SOST SOST ENSMODP00000045584 ENSMODP00000045584 CXCR4 CXCR4 CCR6 CCR6 NRROS NRROS ACKR2 ACKR2 LOC100012266 LOC100012266 ENSMODP00000052695 ENSMODP00000052695 LTBP3 LTBP3 GREM2 GREM2 LOC100030002 LOC100030002 IFNGR1 IFNGR1 ENSMODP00000056105 ENSMODP00000056105 PARK7 PARK7 ENSMODP00000058116 ENSMODP00000058116 ENSMODP00000058229 ENSMODP00000058229 ACKR1 ACKR1 TMC8 TMC8 ENSMODP00000060292 ENSMODP00000060292 BMPER BMPER F7BHT6_MONDO F7BHT6_MONDO IL23R IL23R LEPR LEPR SOSTDC1 SOSTDC1 GDF5 GDF5 IL1R2 IL1R2 IL1RL1 IL1RL1 IL18R1 IL18R1 CRLF1 CRLF1 COMP COMP FZD4 FZD4 IL5RA IL5RA IL13RA2 IL13RA2 TNFRSF11A TNFRSF11A IL2RG IL2RG LRRC32 LRRC32 ENG ENG TGFB3 TGFB3 CHRDL2 CHRDL2 TRIM16 TRIM16 COPS5 COPS5 LTBP4 LTBP4 CNTFR CNTFR CSF1R CSF1R ITGAV ITGAV CX3CR1 CX3CR1 CCR4 CCR4 F7BDF0_MONDO F7BDF0_MONDO F7BDC7_MONDO F7BDC7_MONDO BMPR1A BMPR1A IL12A IL12A CCR9 CCR9 CCR1 CCR1 F6W0U8_MONDO F6W0U8_MONDO CCRL2 CCRL2 IL13RA1 IL13RA1 WFIKKN2 WFIKKN2 TGFBR1 TGFBR1 TCAP TCAP CCR7 CCR7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
IL22RA1Fibronectin type-III domain-containing protein. (633 aa)
CXCR5C-X-C motif chemokine receptor 5; Belongs to the G-protein coupled receptor 1 family. (375 aa)
IL10RAFibronectin type-III domain-containing protein. (605 aa)
IL1RNInterleukin-1. (174 aa)
IL36RNInterleukin-1. (143 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
CCR10C-C motif chemokine receptor 10; Belongs to the G-protein coupled receptor 1 family. (360 aa)
CER1Cerberus 1, DAN family BMP antagonist. (265 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (564 aa)
LTBP1Latent transforming growth factor beta binding protein 1. (1744 aa)
LOC100012302G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (362 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (553 aa)
UCMAUpper zone of growth plate and cartilage matrix associated. (137 aa)
F6WYG5_MONDOHCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (231 aa)
IL20RAInterleukin 20 receptor subunit alpha. (506 aa)
CSF3RUncharacterized protein. (866 aa)
TNFRSF1AUncharacterized protein. (453 aa)
IL20RBInterleukin 20 receptor subunit beta. (311 aa)
HJVHemojuvelin BMP co-receptor. (427 aa)
IL17FUncharacterized protein. (161 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (156 aa)
BMPR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (534 aa)
IL31RAUncharacterized protein. (728 aa)
IL6STInterleukin 6 signal transducer. (923 aa)
OSMRUncharacterized protein. (908 aa)
LIFRLIF receptor subunit alpha. (1101 aa)
IFNAR1Uncharacterized protein. (565 aa)
TWSG1Twisted gastrulation BMP signaling modulator 1. (222 aa)
ACKR3Atypical chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (330 aa)
ACKR4Atypical chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (350 aa)
CCR3C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (356 aa)
XCR1X-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (336 aa)
EBI3Fibronectin type-III domain-containing protein. (242 aa)
TSKUTsukushi, small leucine rich proteoglycan. (353 aa)
IL6RInterleukin-6 receptor alpha. (467 aa)
CD4CD4. (461 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (967 aa)
IL3RAIL6Ra-bind domain-containing protein. (320 aa)
TNFRSF9Uncharacterized protein. (277 aa)
K7E4W0_MONDOFibronectin type-III domain-containing protein. (529 aa)
CD74CD74 molecule. (281 aa)
CRLF2Uncharacterized protein. (369 aa)
GREM1Gremlin. (184 aa)
LOC103094977Uncharacterized protein. (391 aa)
ENSMODP00000041557Uncharacterized protein. (223 aa)
ENSMODP00000041663Uncharacterized protein. (668 aa)
KLHL20Kelch like family member 20. (633 aa)
ENSMODP00000043446G_PROTEIN_RECEP_F1_2 domain-containing protein. (155 aa)
ACVR1TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (559 aa)
SOSTSclerostin. (214 aa)
ENSMODP00000045584G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (343 aa)
CXCR4G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (375 aa)
CCR6G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (370 aa)
NRROSNegative regulator of reactive oxygen species. (782 aa)
ACKR2Atypical chemokine receptor 2; Belongs to the G-protein coupled receptor 1 family. (388 aa)
LOC100012266G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (353 aa)
ENSMODP00000052695Uncharacterized protein. (143 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1267 aa)
GREM2Gremlin 2, DAN family BMP antagonist. (187 aa)
LOC100030002G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (352 aa)
IFNGR1Fibronectin type-III domain-containing protein. (503 aa)
ENSMODP00000056105Uncharacterized protein. (194 aa)
PARK7DJ-1_PfpI domain-containing protein. (189 aa)
ENSMODP00000058116G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (343 aa)
ENSMODP00000058229Uncharacterized protein. (86 aa)
ACKR1Uncharacterized protein. (304 aa)
TMC8Transmembrane channel-like protein. (729 aa)
ENSMODP00000060292Uncharacterized protein. (255 aa)
BMPERBMP binding endothelial regulator. (686 aa)
F7BHT6_MONDOUncharacterized protein. (807 aa)
IL23RUncharacterized protein. (604 aa)
LEPRUncharacterized protein. (893 aa)
SOSTDC1Sclerostin domain containing 1. (223 aa)
GDF5Growth differentiation factor 5. (495 aa)
IL1R2Uncharacterized protein. (414 aa)
IL1RL1Uncharacterized protein. (546 aa)
IL18R1Uncharacterized protein. (533 aa)
CRLF1Cytokine receptor like factor 1. (403 aa)
COMPCartilage oligomeric matrix protein. (728 aa)
FZD4Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa)
IL5RAIL6Ra-bind domain-containing protein. (365 aa)
IL13RA2Uncharacterized protein. (400 aa)
TNFRSF11ATNFR-Cys domain-containing protein. (670 aa)
IL2RGFibronectin type-III domain-containing protein. (301 aa)
LRRC32Leucine rich repeat containing 32. (670 aa)
ENGZP domain-containing protein. (654 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
CHRDL2Chordin like 2. (429 aa)
TRIM16Uncharacterized protein. (553 aa)
COPS5COP9 signalosome subunit 5. (334 aa)
LTBP4Latent transforming growth factor beta binding protein 4. (1488 aa)
CNTFRCiliary neurotrophic factor receptor. (368 aa)
CSF1RColony stimulating factor 1 receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (959 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1058 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
CCR4C-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (354 aa)
F7BDF0_MONDOG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (358 aa)
F7BDC7_MONDOG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (349 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (336 aa)
CCR1C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (363 aa)
F6W0U8_MONDOG_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (361 aa)
CCRL2G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (338 aa)
IL13RA1Interleukin 13 receptor subunit alpha 1. (423 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (567 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
TCAPTitin-cap. (171 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (374 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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