STRINGSTRING
STX4 STX4 PARVB PARVB SNX2 SNX2 CLRN1 CLRN1 FAT1 FAT1 CDK5 CDK5 CTNND1 CTNND1 ENSMODP00000057679 ENSMODP00000057679 ABI2 ABI2 ENSMODP00000057584 ENSMODP00000057584 ENSMODP00000057283 ENSMODP00000057283 ENSMODP00000057145 ENSMODP00000057145 ENSMODP00000056454 ENSMODP00000056454 GDPD2 GDPD2 ENSMODP00000056300 ENSMODP00000056300 PLEKHG5 PLEKHG5 SRCIN1 SRCIN1 EVL EVL ENSMODP00000055788 ENSMODP00000055788 CTNNA2 CTNNA2 ROCK1 ROCK1 RAB13 RAB13 ENSMODP00000055409 ENSMODP00000055409 STMN2 STMN2 ENSMODP00000055038 ENSMODP00000055038 RAC1 RAC1 ITSN1 ITSN1 MYO9B MYO9B NF2 NF2 WASF3 WASF3 CORO6 CORO6 PARVA PARVA RUFY3 RUFY3 ENSMODP00000052695 ENSMODP00000052695 ARHGEF7 ARHGEF7 CTTNBP2NL CTTNBP2NL DGKZ DGKZ CAPG CAPG CARMIL1 CARMIL1 FGD4 FGD4 PKN2 PKN2 ENSMODP00000049511 ENSMODP00000049511 ENSMODP00000049434 ENSMODP00000049434 PLXND1 PLXND1 ENSMODP00000049071 ENSMODP00000049071 ENSMODP00000049041 ENSMODP00000049041 SYNE2 SYNE2 PTPN13 PTPN13 DAG1 DAG1 ABI1 ABI1 CCDC88A CCDC88A DBNL DBNL ENSMODP00000048395 ENSMODP00000048395 PDXP PDXP ILK ILK PALLD PALLD ENSMODP00000046824 ENSMODP00000046824 STX2 STX2 STX3 STX3 KITLG KITLG RAB3IP RAB3IP DUSP22 DUSP22 ENSMODP00000044527 ENSMODP00000044527 BAIAP2 BAIAP2 AVIL AVIL SPATA13 SPATA13 CAPRIN1 CAPRIN1 FGD1 FGD1 ARHGAP31 ARHGAP31 CTTN CTTN AJUBA AJUBA NCKAP1 NCKAP1 ITGB1 ITGB1 PODXL PODXL DPP4 DPP4 F6V6N0_MONDO F6V6N0_MONDO SCYL3 SCYL3 ENAH ENAH FSCN3 FSCN3 CARMIL3 CARMIL3 ABI3 ABI3 F7CI75_MONDO F7CI75_MONDO PPP1R9B PPP1R9B CDC42 CDC42 WASF2 WASF2 CORO1C CORO1C DBN1 DBN1 TRPV4 TRPV4 MTSS2 MTSS2 PIK3CA PIK3CA LOC100015800 LOC100015800 PKD2 PKD2 GSN GSN CIB1 CIB1 FLOT2 FLOT2 UNC5C UNC5C PIP5K1A PIP5K1A APBB1 APBB1 WASF1 WASF1 F6TLE1_MONDO F6TLE1_MONDO CTNNA3 CTNNA3 F6WYG5_MONDO F6WYG5_MONDO MEFV MEFV ALS2 ALS2 PTK2B PTK2B FLOT1 FLOT1 CORO1A CORO1A NRBP1 NRBP1 ARPC2 ARPC2 VIL1 VIL1 WASL WASL F6XEP3_MONDO F6XEP3_MONDO CIB3 CIB3 ITGB1BP1 ITGB1BP1 F6T9J4_MONDO F6T9J4_MONDO ARHGEF6 ARHGEF6 PDLIM4 PDLIM4 LIMK1 LIMK1 CDC42BPB CDC42BPB APC APC TSC1 TSC1 NME2 NME2 ABITRAM ABITRAM CTNNA1 CTNNA1 F6U132_MONDO F6U132_MONDO CTNNB1 CTNNB1 SNX1 SNX1 PHACTR4 PHACTR4 ITGB3 ITGB3 ITGAV ITGAV DPYSL3 DPYSL3 ABLIM1 ABLIM1 KPTN KPTN INPPL1 INPPL1 SWAP70 SWAP70 ARPC5 ARPC5 F7G4H7_MONDO F7G4H7_MONDO VAMP7 VAMP7 PLCE1 PLCE1 CARMIL2 CARMIL2 ABLIM3 ABLIM3 BRK1 BRK1 APC2 APC2 AMOT AMOT MYO10 MYO10 EPHA2 EPHA2 RAC3 RAC3 P4HB P4HB SH3RF1 SH3RF1 KLHL2 KLHL2 RAC2 RAC2 PLCG1 PLCG1 CYFIP1 CYFIP1 PLEKHH2 PLEKHH2 SLC39A6 SLC39A6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
STX4Syntaxin 4; Belongs to the syntaxin family. (297 aa)
PARVBParvin beta. (381 aa)
SNX2Sorting nexin 2. (523 aa)
CLRN1Uncharacterized protein. (231 aa)
FAT1Uncharacterized protein. (4500 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
CTNND1Catenin delta 1. (965 aa)
ENSMODP00000057679Coronin; Belongs to the WD repeat coronin family. (236 aa)
ABI2Abl interactor 2. (566 aa)
ENSMODP00000057584Uncharacterized protein. (86 aa)
ENSMODP00000057283Thioredoxin domain-containing protein. (163 aa)
ENSMODP00000057145Thioredoxin domain-containing protein. (157 aa)
ENSMODP00000056454Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (149 aa)
GDPD2Glycerophosphodiester phosphodiesterase domain containing 2. (490 aa)
ENSMODP00000056300Uncharacterized protein. (116 aa)
PLEKHG5Pleckstrin homology and RhoGEF domain containing G5. (1145 aa)
SRCIN1SRC kinase signaling inhibitor 1. (1358 aa)
EVLEnah/Vasp-like; Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. Belongs to the Ena/VASP family. (422 aa)
ENSMODP00000055788Uncharacterized protein. (202 aa)
CTNNA2Uncharacterized protein. (651 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1322 aa)
RAB13Uncharacterized protein. (140 aa)
ENSMODP00000055409Uncharacterized protein. (362 aa)
STMN2Stathmin; Belongs to the stathmin family. (168 aa)
ENSMODP00000055038Thioredoxin domain-containing protein. (65 aa)
RAC1Rac family small GTPase 1. (269 aa)
ITSN1Intersectin 1. (1218 aa)
MYO9BMyosin IXB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2036 aa)
NF2Neurofibromin 2. (595 aa)
WASF3WASP family member 3. (503 aa)
CORO6Coronin; Belongs to the WD repeat coronin family. (502 aa)
PARVAParvin alpha. (380 aa)
RUFY3RUN and FYVE domain containing 3. (511 aa)
ENSMODP00000052695Uncharacterized protein. (143 aa)
ARHGEF7Rho guanine nucleotide exchange factor 7. (869 aa)
CTTNBP2NLCTTNBP2 N-terminal like. (607 aa)
DGKZDiacylglycerol kinase. (949 aa)
CAPGCapping actin protein, gelsolin like. (424 aa)
CARMIL1Capping protein regulator and myosin 1 linker 1. (1433 aa)
FGD4FYVE, RhoGEF and PH domain containing 4. (897 aa)
PKN2Protein kinase N2. (1013 aa)
ENSMODP00000049511Uncharacterized protein. (54 aa)
ENSMODP00000049434Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (180 aa)
PLXND1Plexin D1. (1911 aa)
ENSMODP00000049071Uncharacterized protein. (380 aa)
ENSMODP00000049041CH_2 domain-containing protein. (387 aa)
SYNE2Spectrin repeat containing nuclear envelope protein 2. (6528 aa)
PTPN13Tyrosine-protein phosphatase non-receptor type 13; Regulates negatively FAS-induced apoptosis and NGFR-mediated pro-apoptotic signaling. (2335 aa)
DAG1Dystroglycan 1. (896 aa)
ABI1Abl interactor 1. (508 aa)
CCDC88ACoiled-coil domain containing 88A. (1829 aa)
DBNLDrebrin like. (430 aa)
ENSMODP00000048395Link domain-containing protein. (346 aa)
PDXPPyridoxal phosphatase. (333 aa)
ILKIntegrin linked kinase. (486 aa)
PALLDPalladin, cytoskeletal associated protein. (1418 aa)
ENSMODP00000046824Uncharacterized protein. (131 aa)
STX2Syntaxin 2; Belongs to the syntaxin family. (288 aa)
STX3Syntaxin 3; Belongs to the syntaxin family. (289 aa)
KITLGKit ligand; Ligand for the receptor-type protein-tyrosine kinase KIT. Plays an essential role in the regulation of cell survival and proliferation, hematopoiesis, stem cell maintenance, gametogenesis, mast cell development, migration and function, and in melanogenesis. Belongs to the SCF family. (273 aa)
RAB3IPSec2p domain-containing protein. (517 aa)
DUSP22Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (235 aa)
ENSMODP00000044527NDK domain-containing protein; Belongs to the NDK family. (143 aa)
BAIAP2BAI1 associated protein 2. (535 aa)
AVILAdvillin. (819 aa)
SPATA13Uncharacterized protein. (1489 aa)
CAPRIN1Cell cycle associated protein 1. (720 aa)
FGD1FYVE, RhoGEF and PH domain containing 1. (978 aa)
ARHGAP31Rho GTPase activating protein 31. (1321 aa)
CTTNCortactin. (517 aa)
AJUBAAjuba LIM protein. (537 aa)
NCKAP1NCK associated protein 1. (1115 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (802 aa)
PODXLUncharacterized protein. (594 aa)
DPP4Dipeptidyl peptidase 4; Belongs to the peptidase S9B family. (806 aa)
F6V6N0_MONDOUncharacterized protein. (1311 aa)
SCYL3SCY1 like pseudokinase 3. (687 aa)
ENAHENAH actin regulator. (825 aa)
FSCN3Fascin. (500 aa)
CARMIL3Capping protein regulator and myosin 1 linker 3. (1356 aa)
ABI3ABI family member 3. (353 aa)
F7CI75_MONDOUncharacterized protein. (223 aa)
PPP1R9BProtein phosphatase 1 regulatory subunit 9B. (807 aa)
CDC42Cell division cycle 42. (191 aa)
WASF2WASP family member 2. (497 aa)
CORO1CCoronin; Belongs to the WD repeat coronin family. (742 aa)
DBN1Drebrin 1. (689 aa)
TRPV4Transient receptor potential cation channel subfamily V member 4. (640 aa)
MTSS2MTSS I-BAR domain containing 2. (741 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC100015800Uncharacterized protein. (440 aa)
PKD2Polycystin 2, transient receptor potential cation channel. (997 aa)
GSNGelsolin. (776 aa)
CIB1Calcium and integrin binding 1. (194 aa)
FLOT2Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (504 aa)
UNC5CUnc-5 netrin receptor C. (931 aa)
PIP5K1APIPK domain-containing protein. (630 aa)
APBB1Amyloid beta precursor protein binding family B member 1. (711 aa)
WASF1WASP family member 1. (546 aa)
F6TLE1_MONDOUncharacterized protein. (164 aa)
CTNNA3Uncharacterized protein. (454 aa)
F6WYG5_MONDOHCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (231 aa)
MEFVUncharacterized protein. (793 aa)
ALS2Alsin Rho guanine nucleotide exchange factor ALS2. (1801 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (984 aa)
FLOT1Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (420 aa)
CORO1ACoronin; Belongs to the WD repeat coronin family. (523 aa)
NRBP1Nuclear receptor binding protein 1. (543 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (330 aa)
VIL1Villin 1. (516 aa)
WASLWASP like actin nucleation promoting factor. (505 aa)
F6XEP3_MONDOCH_2 domain-containing protein. (233 aa)
CIB3Calcium and integrin binding family member 3. (215 aa)
ITGB1BP1Integrin subunit beta 1 binding protein 1. (200 aa)
F6T9J4_MONDOUncharacterized protein. (191 aa)
ARHGEF6Rac/Cdc42 guanine nucleotide exchange factor 6. (777 aa)
PDLIM4PDZ and LIM domain 4. (367 aa)
LIMK1LIM domain kinase 1. (602 aa)
CDC42BPBCDC42 binding protein kinase beta; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1606 aa)
APCAPC regulator of WNT signaling pathway. (2936 aa)
TSC1TSC complex subunit 1. (1152 aa)
NME2Nucleoside diphosphate kinase. (151 aa)
ABITRAMUncharacterized protein. (188 aa)
CTNNA1Uncharacterized protein. (906 aa)
F6U132_MONDOActin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (176 aa)
CTNNB1Catenin beta 1. (781 aa)
SNX1Sorting nexin 1. (524 aa)
PHACTR4Phosphatase and actin regulator. (717 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
ITGAVIntegrin subunit alpha V; Belongs to the integrin alpha chain family. (1058 aa)
DPYSL3Amidohydro-rel domain-containing protein. (686 aa)
ABLIM1Actin binding LIM protein 1. (797 aa)
KPTNKaptin, actin binding protein. (451 aa)
INPPL1Inositol polyphosphate phosphatase like 1. (1013 aa)
SWAP70Switching B cell complex subunit SWAP70. (585 aa)
ARPC5Actin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (304 aa)
F7G4H7_MONDOFERM domain-containing protein. (482 aa)
VAMP7Vesicle associated membrane protein 7; Belongs to the synaptobrevin family. (211 aa)
PLCE1Phosphoinositide phospholipase C. (2291 aa)
CARMIL2Capping protein regulator and myosin 1 linker 2. (1223 aa)
ABLIM3HP domain-containing protein. (293 aa)
BRK1Uncharacterized protein. (106 aa)
APC2APC_N_CC domain-containing protein. (1586 aa)
AMOTAngiomotin. (1015 aa)
MYO10Myosin X; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1309 aa)
EPHA2EPH receptor A2. (886 aa)
RAC3Rac family small GTPase 3. (192 aa)
P4HBProtein disulfide-isomerase. (510 aa)
SH3RF1SH3 domain containing ring finger 1. (871 aa)
KLHL2Kelch like family member 2. (593 aa)
RAC2Rac family small GTPase 2. (281 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1292 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
PLEKHH2Pleckstrin homology, MyTH4 and FERM domain containing H2. (1503 aa)
SLC39A6Solute carrier family 39 member 6. (720 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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