STRINGSTRING
ZBTB7B ZBTB7B LRRC8A LRRC8A NKX2-3 NKX2-3 IKZF1 IKZF1 LMBR1L LMBR1L TMEM98 TMEM98 FADD FADD EGR1 EGR1 MERTK MERTK ATG5 ATG5 CBFB CBFB MTOR MTOR TCIRG1 TCIRG1 THEMIS2 THEMIS2 WNT4 WNT4 DCAF1 DCAF1 ENSMODP00000055825 ENSMODP00000055825 KAT7 KAT7 SYK SYK IFN4 IFN4 ENSMODP00000054960 ENSMODP00000054960 NCAPH2 NCAPH2 CARD11 CARD11 ENSMODP00000054586 ENSMODP00000054586 MFNG MFNG PTPN2 PTPN2 CMTM7 CMTM7 DNAJB9 DNAJB9 WNT1 WNT1 STAT3 STAT3 ENSMODP00000052532 ENSMODP00000052532 TSHR TSHR IL7 IL7 DLL1 DLL1 ENSMODP00000049471 ENSMODP00000049471 FLT3 FLT3 CDK6 CDK6 BAX BAX IFN7 IFN7 CD40LG CD40LG ENSMODP00000048260 ENSMODP00000048260 CD3E CD3E ENSMODP00000045583 ENSMODP00000045583 ENSMODP00000045305 ENSMODP00000045305 PAX1 PAX1 ENSMODP00000044858 ENSMODP00000044858 LEP LEP ENSMODP00000044735 ENSMODP00000044735 RORA RORA ENSMODP00000044459 ENSMODP00000044459 NFAM1 NFAM1 RSAD2 RSAD2 FOXP1 FOXP1 ENSMODP00000042419 ENSMODP00000042419 ENSMODP00000042313 ENSMODP00000042313 IL15 IL15 DLL4 DLL4 ENSMODP00000041557 ENSMODP00000041557 ENSMODP00000041484 ENSMODP00000041484 IL4R IL4R IL9 IL9 CD74 CD74 STK11 STK11 LY6D LY6D ARMC5 ARMC5 K7E0A4_MONDO K7E0A4_MONDO NFIL3 NFIL3 EP300 EP300 LOC100021258 LOC100021258 LIG4 LIG4 KIT KIT CD4 CD4 RAG1 RAG1 RAG2 RAG2 PSMB11 PSMB11 BRAF BRAF F7GFS5_MONDO F7GFS5_MONDO IL6R IL6R EZH2 EZH2 SYVN1 SYVN1 VAV1 VAV1 ZBTB1 ZBTB1 JAK3 JAK3 JMJD6 JMJD6 TCF7 TCF7 AXL AXL PRR7 PRR7 F6YW13_MONDO F6YW13_MONDO NRARP NRARP STAT6 STAT6 F6UH53_MONDO F6UH53_MONDO PKNOX1 PKNOX1 RELB RELB LEF1 LEF1 MALT1 MALT1 IL7R IL7R MS4A1 MS4A1 PTGER4 PTGER4 RC3H2 RC3H2 PIK3R1 PIK3R1 TNFSF8 TNFSF8 FOXN1 FOXN1 SRF SRF F7C7H2_MONDO F7C7H2_MONDO LOC100014708 LOC100014708 ITFG2 ITFG2 CRACR2A CRACR2A RABL3 RABL3 TRAF3IP2 TRAF3IP2 THEMIS THEMIS HECTD1 HECTD1 GON4L GON4L DCLRE1C DCLRE1C SEMA4A SEMA4A GATA3 GATA3 NTRK1 NTRK1 ADA ADA FZD5 FZD5 PTK2B PTK2B PLCG2 PLCG2 EOMES EOMES LOC100012174 LOC100012174 LOC100011470 LOC100011470 JAG2 JAG2 POU2AF1 POU2AF1 FNIP1 FNIP1 BAK1 BAK1 ADGRG3 ADGRG3 IRF1 IRF1 CD3D CD3D SASH3 SASH3 CCR7 CCR7 IKZF3 IKZF3 PTPRC PTPRC TSC1 TSC1 TBX21 TBX21 TUSC2 TUSC2 BTK BTK LYL1 LYL1 F6RKH2_MONDO F6RKH2_MONDO CCR9 CCR9 CTNNB1 CTNNB1 F7BA89_MONDO F7BA89_MONDO CD83 CD83 SLAMF8 SLAMF8 FOXP3 FOXP3 PATZ1 PATZ1 BCL11B BCL11B CD8A CD8A ATF2 ATF2 SP3 SP3 TOX TOX TGFB1 TGFB1 ITK ITK CHD7 CHD7 IRF2BP2 IRF2BP2 GPR18 GPR18 GPR183 GPR183 RIPK2 RIPK2 CDH17 CDH17 CLEC4E CLEC4E FZD8 FZD8 GPS2 GPS2 TPD52 TPD52 MR1 MR1 HHEX HHEX ITPKB ITPKB BATF BATF BCL2 BCL2 TNFSF13B TNFSF13B BLNK BLNK HLX HLX IRF8 IRF8 RORC RORC IFNK IFNK RC3H1 RC3H1 ITM2A ITM2A TCF3 TCF3 IFN3 IFN3 ENTPD7 ENTPD7 ZAP70 ZAP70 GLI3 GLI3 IL18R1 IL18R1 ANXA1 ANXA1 FBXO7 FBXO7 IL6 IL6 SOX13 SOX13 LEPR LEPR MSH2 MSH2 ST3GAL1 ST3GAL1 F6YRI3_MONDO F6YRI3_MONDO ZBTB7A ZBTB7A LGALS1 LGALS1 LFNG LFNG TYRO3 TYRO3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ZBTB7BZinc finger and BTB domain containing 7B. (516 aa)
LRRC8ALeucine rich repeat containing 8 VRAC subunit A. (999 aa)
NKX2-3NK2 homeobox 3. (345 aa)
IKZF1IKAROS family zinc finger 1. (594 aa)
LMBR1LLimb development membrane protein 1 like; Belongs to the LIMR family. (490 aa)
TMEM98Uncharacterized protein. (226 aa)
FADDUncharacterized protein. (193 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (527 aa)
MERTKMER proto-oncogene, tyrosine kinase. (973 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (277 aa)
CBFBCore-binding factor subunit beta. (222 aa)
MTORSerine/threonine-protein kinase mTOR. (1040 aa)
TCIRG1V-type proton ATPase subunit a; Essential component of the vacuolar proton pump (V-ATPase), a multimeric enzyme that catalyzes the translocation of protons across the membranes. Required for assembly and activity of the V-ATPase. (559 aa)
THEMIS2CABIT domain-containing protein. (90 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
DCAF1DDB1 and CUL4 associated factor 1. (1575 aa)
ENSMODP00000055825Galectin. (125 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (614 aa)
SYKTyrosine-protein kinase. (588 aa)
IFN4Type I interferon 4. (183 aa)
ENSMODP00000054960Uncharacterized protein. (418 aa)
NCAPH2CNDH2_N domain-containing protein. (225 aa)
CARD11Caspase recruitment domain family member 11. (1176 aa)
ENSMODP00000054586DUF3398 domain-containing protein. (189 aa)
MFNGUncharacterized protein. (316 aa)
PTPN2Tyrosine-protein phosphatase non-receptor type. (403 aa)
CMTM7MARVEL domain-containing protein. (185 aa)
DNAJB9J domain-containing protein. (219 aa)
WNT1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (335 aa)
STAT3Signal transducer and activator of transcription. (805 aa)
ENSMODP00000052532Uncharacterized protein. (398 aa)
TSHRThyrotropin receptor; Receptor for the thyroid-stimulating hormone (TSH) or thyrotropin. Also acts as a receptor for the heterodimeric glycoprotein hormone (GPHA2:GPHB5) or thyrostimulin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Plays a central role in controlling thyroid cell metabolism. Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (769 aa)
IL7Uncharacterized protein. (205 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (734 aa)
ENSMODP00000049471Uncharacterized protein. (696 aa)
FLT3Fms related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (976 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (390 aa)
BAXUncharacterized protein. (296 aa)
IFN7Type I interferon 7. (183 aa)
CD40LGCD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (251 aa)
ENSMODP00000048260Galectin. (135 aa)
CD3EIGc2 domain-containing protein. (252 aa)
ENSMODP00000045583A_deaminase domain-containing protein. (79 aa)
ENSMODP00000045305Galectin. (120 aa)
PAX1Paired box 1. (349 aa)
ENSMODP00000044858A_deaminase domain-containing protein. (83 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
ENSMODP00000044735Uncharacterized protein. (696 aa)
RORARAR related orphan receptor A. (523 aa)
ENSMODP00000044459Galectin. (135 aa)
NFAM1Uncharacterized protein. (396 aa)
RSAD2Radical S-adenosyl methionine domain containing 2. (267 aa)
FOXP1Fork-head domain-containing protein. (693 aa)
ENSMODP00000042419Uncharacterized protein. (1127 aa)
ENSMODP00000042313Uncharacterized protein. (84 aa)
IL15Interleukin; Belongs to the IL-15/IL-21 family. (183 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (713 aa)
ENSMODP00000041557Uncharacterized protein. (223 aa)
ENSMODP00000041484Uncharacterized protein. (86 aa)
IL4RIL4Ra_N domain-containing protein. (930 aa)
IL9Uncharacterized protein. (167 aa)
CD74CD74 molecule. (281 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (414 aa)
LY6DUPAR/Ly6 domain-containing protein. (117 aa)
ARMC5Armadillo repeat containing 5. (969 aa)
K7E0A4_MONDOUncharacterized protein. (667 aa)
NFIL3Nuclear factor, interleukin 3 regulated. (460 aa)
EP300E1A binding protein p300. (2454 aa)
LOC100021258Type I interferon 1. (198 aa)
LIG4DNA ligase. (911 aa)
KITMast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (967 aa)
CD4CD4. (461 aa)
RAG1V(D)J recombination-activating protein 1; Catalytic component of the RAG complex, a multiprotein complex that mediates the DNA cleavage phase during V(D)J recombination. V(D)J recombination assembles a diverse repertoire of immunoglobulin and T-cell receptor genes in developing B and T- lymphocytes through rearrangement of different V (variable), in some cases D (diversity), and J (joining) gene segments. In the RAG complex, RAG1 mediates the DNA-binding to the conserved recombination signal sequences (RSS) and catalyzes the DNA cleavage activities by introducing a double-strand break [...] (1047 aa)
RAG2Recombination activating 2. (527 aa)
PSMB11Proteasome subunit beta. (261 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (563 aa)
F7GFS5_MONDOUncharacterized protein. (1113 aa)
IL6RInterleukin-6 receptor alpha. (467 aa)
EZH2Uncharacterized protein. (665 aa)
SYVN1Synoviolin 1. (592 aa)
VAV1Vav guanine nucleotide exchange factor 1. (846 aa)
ZBTB1Zinc finger and BTB domain containing 1. (643 aa)
JAK3Tyrosine-protein kinase. (1097 aa)
JMJD6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (412 aa)
TCF7Transcription factor 7. (442 aa)
AXLAXL receptor tyrosine kinase. (886 aa)
PRR7Proline rich 7, synaptic. (280 aa)
F6YW13_MONDODNA_MISMATCH_REPAIR_2 domain-containing protein. (641 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
STAT6Signal transducer and activator of transcription. (839 aa)
F6UH53_MONDOUncharacterized protein; Belongs to the DOCK family. (1730 aa)
PKNOX1PBX/knotted 1 homeobox 1. (503 aa)
RELBRELB proto-oncogene, NF-kB subunit. (621 aa)
LEF1Lymphoid enhancer binding factor 1. (401 aa)
MALT1MALT1 paracaspase. (789 aa)
IL7RFibronectin type-III domain-containing protein. (456 aa)
MS4A1Membrane spanning 4-domains A1. (287 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (521 aa)
RC3H2Ring finger and CCCH-type domains 2. (1196 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (731 aa)
TNFSF8TNF superfamily member 8; Belongs to the tumor necrosis factor family. (235 aa)
FOXN1Forkhead box N1. (636 aa)
SRFSerum response factor. (490 aa)
F7C7H2_MONDOInterleukin; Belongs to the IL-15/IL-21 family. (158 aa)
LOC100014708Uncharacterized protein. (466 aa)
ITFG2Uncharacterized protein. (439 aa)
CRACR2ACalcium release activated channel regulator 2A. (709 aa)
RABL3RAB, member of RAS oncogene family like 3. (236 aa)
TRAF3IP2TRAF3 interacting protein 2. (571 aa)
THEMISThymocyte selection associated. (647 aa)
HECTD1HECT domain E3 ubiquitin protein ligase 1. (2610 aa)
GON4LMyb-like domain-containing protein. (2199 aa)
DCLRE1CDNA cross-link repair 1C. (684 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (790 aa)
GATA3GATA binding protein 3. (444 aa)
NTRK1Tyrosine-protein kinase receptor. (739 aa)
ADAAdenosine deaminase. (334 aa)
FZD5Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (592 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (984 aa)
PLCG21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1264 aa)
EOMESUncharacterized protein. (665 aa)
LOC100012174Signal transducer and activator of transcription. (782 aa)
LOC100011470Signal transducer and activator of transcription. (839 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1247 aa)
POU2AF1POU class 2 homeobox associating factor 1. (279 aa)
FNIP1Folliculin interacting protein 1. (1214 aa)
BAK1BCL2 antagonist/killer 1. (204 aa)
ADGRG3Uncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (476 aa)
IRF1Interferon regulatory factor. (325 aa)
CD3DIg_4 domain-containing protein. (272 aa)
SASH3SAM and SH3 domain containing 3. (390 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (374 aa)
IKZF3IKAROS family zinc finger 3. (514 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1142 aa)
TSC1TSC complex subunit 1. (1152 aa)
TBX21T-box_assoc domain-containing protein. (575 aa)
TUSC2Uncharacterized protein. (268 aa)
BTKTyrosine-protein kinase. (655 aa)
LYL1BHLH domain-containing protein. (432 aa)
F6RKH2_MONDOUncharacterized protein. (467 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (336 aa)
CTNNB1Catenin beta 1. (781 aa)
F7BA89_MONDOUncharacterized protein; Belongs to the PI3/PI4-kinase family. (740 aa)
CD83Ig-like domain-containing protein. (210 aa)
SLAMF8SLAM family member 8. (279 aa)
FOXP3C2H2-type domain-containing protein. (365 aa)
PATZ1POZ/BTB and AT hook containing zinc finger 1. (668 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (884 aa)
CD8AIg-like domain-containing protein. (340 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
SP3Sp3 transcription factor. (785 aa)
TOXThymocyte selection associated high mobility group box. (525 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa)
ITKTyrosine-protein kinase. (620 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2999 aa)
IRF2BP2Interferon regulatory factor 2 binding protein 2. (612 aa)
GPR18G protein-coupled receptor 18; Belongs to the G-protein coupled receptor 1 family. (330 aa)
GPR183G protein-coupled receptor 183; Belongs to the G-protein coupled receptor 1 family. (355 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (540 aa)
CDH17Cadherin 17. (829 aa)
CLEC4EC-type lectin domain family 4 member E. (224 aa)
FZD8Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (710 aa)
GPS2G protein pathway suppressor 2. (325 aa)
TPD52Uncharacterized protein. (362 aa)
MR1MHC class I-related protein; Belongs to the MHC class I family. (340 aa)
HHEXHomeobox domain-containing protein. (277 aa)
ITPKBKinase; Belongs to the inositol phosphokinase (IPK) family. (990 aa)
BATFBasic leucine zipper ATF-like transcription factor. (137 aa)
BCL2BCL2 apoptosis regulator. (188 aa)
TNFSF13BTNF superfamily member 13b; Belongs to the tumor necrosis factor family. (286 aa)
BLNKB cell linker. (466 aa)
HLXH2.0 like homeobox. (486 aa)
IRF8IRF-3 domain-containing protein. (219 aa)
RORCRAR related orphan receptor C. (514 aa)
IFNKType I interferon 9. (202 aa)
RC3H1Ring finger and CCCH-type domains 1. (1134 aa)
ITM2AIntegral membrane protein 2A. (344 aa)
TCF3Transcription factor 3. (544 aa)
IFN3Uncharacterized protein. (184 aa)
ENTPD7Ectonucleoside triphosphate diphosphohydrolase 7; Belongs to the GDA1/CD39 NTPase family. (604 aa)
ZAP70Tyrosine-protein kinase. (619 aa)
GLI3GLI family zinc finger 3. (1501 aa)
IL18R1Uncharacterized protein. (533 aa)
ANXA1Annexin. (346 aa)
FBXO7F-box protein 7. (518 aa)
IL6Uncharacterized protein. (220 aa)
SOX13SRY-box transcription factor 13. (527 aa)
LEPRUncharacterized protein. (893 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (969 aa)
ST3GAL1ST3 beta-galactoside alpha-2,3-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (342 aa)
F6YRI3_MONDOUncharacterized protein. (647 aa)
ZBTB7AZinc finger and BTB domain containing 7A. (508 aa)
LGALS1Galectin. (135 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (399 aa)
TYRO3TYRO3 protein tyrosine kinase. (820 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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