32 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AP1G1	AP-1 complex subunit gamma. (829 aa)
	CLTB	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (226 aa)
	AP1S1	Clat_adaptor_s domain-containing protein. (344 aa)
	AP1G2	AP-1 complex subunit gamma. (785 aa)
	AFTPH	Aftiphilin. (925 aa)
	NECAP2	NECAP endocytosis associated 2. (266 aa)
	CLTA	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (253 aa)
	SYNRG	Synergin gamma. (1228 aa)
	CLHC1	Clathrin heavy chain linker domain-containing protein 1. (588 aa)
	SLC18A3	Solute carrier family 18 member A3. (529 aa)
	F7C9S0_MONDO	Uncharacterized protein. (369 aa)
	AP1S3	Clat_adaptor_s domain-containing protein. (257 aa)
	EPN1	Uncharacterized protein. (304 aa)
	C1H14orf79	Clathrin_bdg domain-containing protein. (353 aa)
	CLTC	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1686 aa)
	CLINT1	Clathrin interactor 1. (594 aa)
	ENSMODP00000041866	Clat_adaptor_s domain-containing protein. (92 aa)
	SGIP1	SH3 domain GRB2 like endophilin interacting protein 1. (801 aa)
	ENSMODP00000047462	ENTH domain-containing protein. (106 aa)
	AP1S2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
	ENSMODP00000049347	Adaptin_N domain-containing protein. (283 aa)
	AP2S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (150 aa)
	AP2M1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (437 aa)
	EPN3	Epsin 3. (640 aa)
	ENSMODP00000056612	Clat_adaptor_s domain-containing protein. (84 aa)
	ENSMODP00000057003	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (147 aa)
	SSC5D	Uncharacterized protein. (1298 aa)
	CLTCL1	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family. (1556 aa)
	ENTHD1	ENTH domain-containing protein. (692 aa)
	ENSMODP00000057257	Uncharacterized protein. (66 aa)
	NECAP1	NECAP endocytosis associated 1. (180 aa)
	EPN2	Epsin 2. (644 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFTPH	AP1G1	ENSMODP00000003938	ENSMODP00000002934	Aftiphilin.	AP-1 complex subunit gamma.	0.632
AFTPH	AP1G2	ENSMODP00000003938	ENSMODP00000004686	Aftiphilin.	AP-1 complex subunit gamma.	0.632
AFTPH	AP1S1	ENSMODP00000003938	ENSMODP00000006088	Aftiphilin.	Clat_adaptor_s domain-containing protein.	0.511
AFTPH	AP1S2	ENSMODP00000003938	ENSMODP00000049036	Aftiphilin.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.575
AFTPH	AP1S3	ENSMODP00000003938	ENSMODP00000026493	Aftiphilin.	Clat_adaptor_s domain-containing protein.	0.618
AFTPH	AP2M1	ENSMODP00000003938	ENSMODP00000054481	Aftiphilin.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.566
AFTPH	AP2S1	ENSMODP00000003938	ENSMODP00000052351	Aftiphilin.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.422
AFTPH	C1H14orf79	ENSMODP00000003938	ENSMODP00000039201	Aftiphilin.	Clathrin_bdg domain-containing protein.	0.540
AFTPH	CLINT1	ENSMODP00000003938	ENSMODP00000041850	Aftiphilin.	Clathrin interactor 1.	0.586
AFTPH	CLTA	ENSMODP00000003938	ENSMODP00000003171	Aftiphilin.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.564
AFTPH	CLTB	ENSMODP00000003938	ENSMODP00000006390	Aftiphilin.	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family.	0.567
AFTPH	CLTC	ENSMODP00000003938	ENSMODP00000041726	Aftiphilin.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.580
AFTPH	CLTCL1	ENSMODP00000003938	ENSMODP00000012659	Aftiphilin.	Clathrin heavy chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin heavy chain family.	0.580
AFTPH	ENSMODP00000057003	ENSMODP00000003938	ENSMODP00000057003	Aftiphilin.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.575
AFTPH	ENTHD1	ENSMODP00000003938	ENSMODP00000011227	Aftiphilin.	ENTH domain-containing protein.	0.540
AFTPH	EPN1	ENSMODP00000003938	ENSMODP00000017546	Aftiphilin.	Uncharacterized protein.	0.623
AFTPH	EPN2	ENSMODP00000003938	ENSMODP00000060091	Aftiphilin.	Epsin 2.	0.540
AFTPH	EPN3	ENSMODP00000003938	ENSMODP00000056548	Aftiphilin.	Epsin 3.	0.540
AFTPH	NECAP2	ENSMODP00000003938	ENSMODP00000003784	Aftiphilin.	NECAP endocytosis associated 2.	0.540
AFTPH	SLC18A3	ENSMODP00000003938	ENSMODP00000003060	Aftiphilin.	Solute carrier family 18 member A3.	0.540