24 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	AP1G2	AP-1 complex subunit gamma. (785 aa)
	AP4M1	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...] (477 aa)
	ENSMODP00000057003	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (147 aa)
	AP2M1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (437 aa)
	ENSMODP00000056612	Clat_adaptor_s domain-containing protein. (84 aa)
	AP4B1	AP complex subunit beta; Belongs to the adaptor complexes large subunit family. (738 aa)
	AP1G1	AP-1 complex subunit gamma. (829 aa)
	SLC18A3	Solute carrier family 18 member A3. (529 aa)
	AFTPH	Aftiphilin. (925 aa)
	AP1S1	Clat_adaptor_s domain-containing protein. (344 aa)
	AP1M2	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (425 aa)
	AP1B1	AP complex subunit beta. (956 aa)
	AP3M1	AP-3 complex subunit mu-1; Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes; Belongs to the adaptor complexes medium subunit family. (418 aa)
	AP2B1	AP complex subunit beta. (951 aa)
	AP1S3	Clat_adaptor_s domain-containing protein. (257 aa)
	AP1M1	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules. (432 aa)
	C1H14orf79	Clathrin_bdg domain-containing protein. (353 aa)
	ENSMODP00000041866	Clat_adaptor_s domain-containing protein. (92 aa)
	AP3M2	AP-3 complex subunit mu-2. (418 aa)
	SGIP1	SH3 domain GRB2 like endophilin interacting protein 1. (801 aa)
	AP3B1	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family. (1097 aa)
	AP1S2	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (160 aa)
	ENSMODP00000049347	Adaptin_N domain-containing protein. (283 aa)
	AP2S1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (150 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AFTPH	AP1B1	ENSMODP00000003938	ENSMODP00000011033	Aftiphilin.	AP complex subunit beta.	0.424
AFTPH	AP1G1	ENSMODP00000003938	ENSMODP00000002934	Aftiphilin.	AP-1 complex subunit gamma.	0.632
AFTPH	AP1G2	ENSMODP00000003938	ENSMODP00000004686	Aftiphilin.	AP-1 complex subunit gamma.	0.632
AFTPH	AP1M1	ENSMODP00000003938	ENSMODP00000031750	Aftiphilin.	AP-1 complex subunit mu-1; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.573
AFTPH	AP1M2	ENSMODP00000003938	ENSMODP00000007224	Aftiphilin.	AP-1 complex subunit mu-2; Subunit of clathrin-associated adaptor protein complex 1 that plays a role in protein sorting in the trans-Golgi network (TGN) and endosomes. The AP complexes mediate the recruitment of clathrin to membranes and the recognition of sorting signals within the cytosolic tails of transmembrane cargo molecules.	0.573
AFTPH	AP1S1	ENSMODP00000003938	ENSMODP00000006088	Aftiphilin.	Clat_adaptor_s domain-containing protein.	0.511
AFTPH	AP1S2	ENSMODP00000003938	ENSMODP00000049036	Aftiphilin.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.575
AFTPH	AP1S3	ENSMODP00000003938	ENSMODP00000026493	Aftiphilin.	Clat_adaptor_s domain-containing protein.	0.618
AFTPH	AP2B1	ENSMODP00000003938	ENSMODP00000023872	Aftiphilin.	AP complex subunit beta.	0.416
AFTPH	AP2M1	ENSMODP00000003938	ENSMODP00000054481	Aftiphilin.	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	0.566
AFTPH	AP2S1	ENSMODP00000003938	ENSMODP00000052351	Aftiphilin.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.422
AFTPH	AP3B1	ENSMODP00000003938	ENSMODP00000047822	Aftiphilin.	AP-3 complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.419
AFTPH	AP4B1	ENSMODP00000003938	ENSMODP00000000838	Aftiphilin.	AP complex subunit beta; Belongs to the adaptor complexes large subunit family.	0.400
AFTPH	AP4M1	ENSMODP00000003938	ENSMODP00000057754	Aftiphilin.	AP-4 complex subunit mu-1; Component of the adaptor protein complex 4 (AP-4). Adaptor protein complexes are vesicle coat components involved both in vesicle formation and cargo selection. They control the vesicular transport of proteins in different trafficking pathways. AP-4 forms a non clathrin- associated coat on vesicles departing the trans-Golgi network (TGN) and may be involved in the targeting of proteins from the trans-Golgi network (TGN) to the endosomal-lysosomal system. It is also involved in protein sorting to the basolateral membrane in epithelial cells and the proper asym [...]	0.573
AFTPH	C1H14orf79	ENSMODP00000003938	ENSMODP00000039201	Aftiphilin.	Clathrin_bdg domain-containing protein.	0.540
AFTPH	ENSMODP00000057003	ENSMODP00000003938	ENSMODP00000057003	Aftiphilin.	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.575
AFTPH	SLC18A3	ENSMODP00000003938	ENSMODP00000003060	Aftiphilin.	Solute carrier family 18 member A3.	0.540
AP1B1	AFTPH	ENSMODP00000011033	ENSMODP00000003938	AP complex subunit beta.	Aftiphilin.	0.424
AP1B1	AP1G1	ENSMODP00000011033	ENSMODP00000002934	AP complex subunit beta.	AP-1 complex subunit gamma.	0.991
AP1B1	AP1G2	ENSMODP00000011033	ENSMODP00000004686	AP complex subunit beta.	AP-1 complex subunit gamma.	0.991