STRINGSTRING
ANKH ANKH GDF10 GDF10 DDR2 DDR2 PKDCC PKDCC CSF1 CSF1 TENT5A TENT5A CCR3 CCR3 GREM1 GREM1 AHSG AHSG MIA3 MIA3 F6XW95_MONDO F6XW95_MONDO SGMS2 SGMS2 KREMEN2 KREMEN2 MEF2C MEF2C ACVR1 ACVR1 CCN1 CCN1 SOST SOST ACVR2B ACVR2B ENSMODP00000051185 ENSMODP00000051185 ATP2B1 ATP2B1 TFAP2A TFAP2A LTBP3 LTBP3 INTU INTU SMAD7 SMAD7 WNT4 WNT4 ENSMODP00000059044 ENSMODP00000059044 ATRAID ATRAID BMP2K BMP2K BCOR BCOR CYP27B1 CYP27B1 ISG15 ISG15 F7C3T6_MONDO F7C3T6_MONDO NIPBL NIPBL PTGER4 PTGER4 ADGRV1 ADGRV1 LRP4 LRP4 H9H7E3_MONDO H9H7E3_MONDO BMPR1B BMPR1B CYP27C1 CYP27C1 FGF23 FGF23 MAPK1 MAPK1 ZMPSTE24 ZMPSTE24 TXLNG TXLNG EGR2 EGR2 MATN1 MATN1 F6VNB0_MONDO F6VNB0_MONDO F7ASC3_MONDO F7ASC3_MONDO DKK1 DKK1 BMPR2 BMPR2 PTK2B PTK2B MAPK3 MAPK3 NBR1 NBR1 KREMEN1 KREMEN1 F7E823_MONDO F7E823_MONDO ZBTB16 ZBTB16 PTN PTN BMP4 BMP4 DHRS3 DHRS3 P2RX7 P2RX7 CCR1 CCR1 BMPR1A BMPR1A ALOX5 ALOX5 OSR1 OSR1 GATA1 GATA1 BMP6 BMP6 SMAD6 SMAD6 HIF1A HIF1A PTH PTH TGFB1 TGFB1 FAM20C FAM20C ACTN3 ACTN3 RFLNB RFLNB TPH1 TPH1 TGFB3 TGFB3 BCL2 BCL2 TGFB2 TGFB2 BMP2 BMP2 COMP COMP ACVR2A ACVR2A NOTUM NOTUM PTPN11 PTPN11
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ANKHANKH inorganic pyrophosphate transport regulator. (492 aa)
GDF10Growth differentiation factor 10. (493 aa)
DDR2Discoidin domain receptor tyrosine kinase 2. (879 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (490 aa)
CSF1Uncharacterized protein. (340 aa)
TENT5AUncharacterized protein. (427 aa)
CCR3C-C motif chemokine receptor 3; Belongs to the G-protein coupled receptor 1 family. (356 aa)
GREM1Gremlin. (184 aa)
AHSGUncharacterized protein. (364 aa)
MIA3SH3 domain-containing protein. (1252 aa)
F6XW95_MONDOP2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (567 aa)
SGMS2PAP2_C domain-containing protein. (365 aa)
KREMEN2Kringle containing transmembrane protein 2. (432 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
ACVR1TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (559 aa)
CCN1Cellular communication network factor 1. (383 aa)
SOSTSclerostin. (214 aa)
ACVR2BSerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (530 aa)
ENSMODP00000051185Uncharacterized protein. (145 aa)
ATP2B1Calcium-transporting ATPase; This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of calcium. (1249 aa)
TFAP2ATranscription factor AP-2 alpha. (444 aa)
LTBP3Latent transforming growth factor beta binding protein 3. (1267 aa)
INTUInturned planar cell polarity protein. (898 aa)
SMAD7Mothers against decapentaplegic homolog. (459 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (328 aa)
ENSMODP00000059044SH2 domain-containing protein. (79 aa)
ATRAIDEGF-like domain-containing protein. (229 aa)
BMP2KBMP2 inducible kinase. (1133 aa)
BCORBCL6 corepressor. (1722 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (516 aa)
ISG15Uncharacterized protein. (155 aa)
F7C3T6_MONDOUncharacterized protein. (506 aa)
NIPBLNipped-B protein. (2911 aa)
PTGER4Prostaglandin E receptor 4; Belongs to the G-protein coupled receptor 1 family. (521 aa)
ADGRV1Adhesion G protein-coupled receptor V1. (6193 aa)
LRP4LDL receptor related protein 4. (1908 aa)
H9H7E3_MONDOUncharacterized protein; Belongs to the G-protein coupled receptor 2 family. (459 aa)
BMPR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (534 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (372 aa)
FGF23Fibroblast growth factor 23. (193 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (476 aa)
TXLNGTaxilin gamma. (526 aa)
EGR2Early growth response 2. (395 aa)
MATN1Uncharacterized protein. (488 aa)
F6VNB0_MONDOOsteocalcin; Binds strongly to apatite and calcium. (131 aa)
F7ASC3_MONDOUncharacterized protein. (274 aa)
DKK1Dickkopf WNT signaling pathway inhibitor 1. (289 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (984 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
NBR1NBR1 autophagy cargo receptor. (1012 aa)
KREMEN1Kremen protein; Receptor for Dickkopf proteins. Cooperates with DKK1/2 to inhibit Wnt/beta-catenin signaling by promoting the endocytosis of Wnt receptors LRP5 and LRP6. (451 aa)
F7E823_MONDOProtein kinase domain-containing protein. (353 aa)
ZBTB16Zinc finger and BTB domain containing 16. (674 aa)
PTNPleiotrophin. (168 aa)
BMP4Bone morphogenetic protein 4. (410 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (275 aa)
P2RX7P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
CCR1C-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (363 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
OSR1Odd-skipped related transcription factor 1. (265 aa)
GATA1GATA binding protein 1. (401 aa)
BMP6Bone morphogenetic protein 6. (534 aa)
SMAD6Mothers against decapentaplegic homolog. (503 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (830 aa)
PTHUncharacterized protein. (137 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa)
FAM20CFAM20C golgi associated secretory pathway kinase. (591 aa)
ACTN3Actinin alpha 3 (gene/pseudogene). (897 aa)
RFLNBRefilin B. (126 aa)
TPH1Tryptophan hydroxylase 1. (472 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
BCL2BCL2 apoptosis regulator. (188 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
BMP2Bone morphogenetic protein 2. (436 aa)
COMPCartilage oligomeric matrix protein. (728 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (513 aa)
NOTUMNotum, palmitoleoyl-protein carboxylesterase. (633 aa)
PTPN11Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (599 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
Server load: low (12%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.