23 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	PML	Uncharacterized protein. (1118 aa)
	MYO6	Myosin VI; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1278 aa)
	ATRX	ATRX chromatin remodeler. (2389 aa)
	CRADD	Death domain-containing protein. (210 aa)
	ENSMODP00000051682	SEA domain-containing protein. (290 aa)
	TFAP4	Transcription factor AP-4. (347 aa)
	BRCA2	Tower domain-containing protein. (3324 aa)
	F6S7P0_MONDO	USP domain-containing protein; Belongs to the peptidase C19 family. (757 aa)
	E2F7	E2F transcription factor 7. (1105 aa)
	PIDD1	Uncharacterized protein. (272 aa)
	RPS6KA6	Ribosomal protein S6 kinase. (771 aa)
	PPM1D	Protein phosphatase, Mg2+/Mn2+ dependent 1D. (601 aa)
	CDKN1A	Cyclin dependent kinase inhibitor 1A. (164 aa)
	SESN2	Sestrin 2. (478 aa)
	KAT5	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (617 aa)
	CHEK2	Checkpoint kinase 2. (531 aa)
	GTSE1	GTSE1_N domain-containing protein. (692 aa)
	BATF	Basic leucine zipper ATF-like transcription factor. (137 aa)
	USP10	Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (794 aa)
	ACER2	Alkaline ceramidase; Hydrolyzes the sphingolipid ceramide into sphingosine and free fatty acid. (275 aa)
	TRIAP1	TP53 regulated inhibitor of apoptosis 1. (76 aa)
	MDM4	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family. (488 aa)
	NDRG1	N-myc downstream regulated 1. (392 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATRX	BRCA2	ENSMODP00000056492	ENSMODP00000033276	ATRX chromatin remodeler.	Tower domain-containing protein.	0.566
ATRX	CHEK2	ENSMODP00000056492	ENSMODP00000010421	ATRX chromatin remodeler.	Checkpoint kinase 2.	0.443
BRCA2	ATRX	ENSMODP00000033276	ENSMODP00000056492	Tower domain-containing protein.	ATRX chromatin remodeler.	0.566
BRCA2	CHEK2	ENSMODP00000033276	ENSMODP00000010421	Tower domain-containing protein.	Checkpoint kinase 2.	0.790
CDKN1A	TFAP4	ENSMODP00000016922	ENSMODP00000034767	Cyclin dependent kinase inhibitor 1A.	Transcription factor AP-4.	0.908
CHEK2	ATRX	ENSMODP00000010421	ENSMODP00000056492	Checkpoint kinase 2.	ATRX chromatin remodeler.	0.443
CHEK2	BRCA2	ENSMODP00000010421	ENSMODP00000033276	Checkpoint kinase 2.	Tower domain-containing protein.	0.790
CHEK2	KAT5	ENSMODP00000010421	ENSMODP00000011971	Checkpoint kinase 2.	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	0.440
CHEK2	MDM4	ENSMODP00000010421	ENSMODP00000001964	Checkpoint kinase 2.	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.	0.759
CHEK2	PPM1D	ENSMODP00000010421	ENSMODP00000017699	Checkpoint kinase 2.	Protein phosphatase, Mg2+/Mn2+ dependent 1D.	0.678
CRADD	PIDD1	ENSMODP00000056382	ENSMODP00000018737	Death domain-containing protein.	Uncharacterized protein.	0.988
KAT5	CHEK2	ENSMODP00000011971	ENSMODP00000010421	Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family.	Checkpoint kinase 2.	0.440
MDM4	CHEK2	ENSMODP00000001964	ENSMODP00000010421	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.	Checkpoint kinase 2.	0.759
MDM4	PML	ENSMODP00000001964	ENSMODP00000037509	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.	Uncharacterized protein.	0.460
MDM4	PPM1D	ENSMODP00000001964	ENSMODP00000017699	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.	Protein phosphatase, Mg2+/Mn2+ dependent 1D.	0.412
PIDD1	CRADD	ENSMODP00000018737	ENSMODP00000056382	Uncharacterized protein.	Death domain-containing protein.	0.988
PML	MDM4	ENSMODP00000037509	ENSMODP00000001964	Uncharacterized protein.	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.	0.460
PPM1D	CHEK2	ENSMODP00000017699	ENSMODP00000010421	Protein phosphatase, Mg2+/Mn2+ dependent 1D.	Checkpoint kinase 2.	0.678
PPM1D	MDM4	ENSMODP00000017699	ENSMODP00000001964	Protein phosphatase, Mg2+/Mn2+ dependent 1D.	Protein Mdm4; Inhibits p53- and p73-mediated cell cycle arrest and apoptosis by binding its transcriptional activation domain. Belongs to the MDM2/MDM4 family.	0.412
TFAP4	CDKN1A	ENSMODP00000034767	ENSMODP00000016922	Transcription factor AP-4.	Cyclin dependent kinase inhibitor 1A.	0.908