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| | RNF8 | E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (497 aa) |
| | CHMP5 | Uncharacterized protein. (219 aa) |
| | JTB | Uncharacterized protein. (170 aa) |
| | SSNA1 | SS nuclear autoantigen 1. (118 aa) |
| | SLC2A1 | Solute carrier family 2 member 1; Belongs to the major facilitator superfamily. Sugar transporter (TC 2.A.1.1) family. (491 aa) |
| | GNAI1 | G protein subunit alpha i1. (354 aa) |
| | CDK1 | Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (297 aa) |
| | ENSMODP00000052422 | UEV domain-containing protein. (123 aa) |
| | AURKB | Aurora kinase B; Belongs to the protein kinase superfamily. (467 aa) |
| | SVIL | Supervillin. (2236 aa) |
| | UVRAG | UV radiation resistance associated. (688 aa) |
| | CHMP4B | Charged multivesicular body protein 4B. (269 aa) |
| | MAPRE3 | Microtubule associated protein RP/EB family member 3. (295 aa) |
| | EML3 | EMAP like 3. (920 aa) |
| | AGBL5 | ATP/GTP binding protein like 5. (1036 aa) |
| | RCC2 | Regulator of chromosome condensation 2. (438 aa) |
| | ENSMODP00000055675 | Uncharacterized protein. (130 aa) |
| | CHMP1A | Uncharacterized protein. (256 aa) |
| | ALKBH4 | Uncharacterized protein. (304 aa) |
| | ENSMODP00000056710 | USP8_dimer domain-containing protein. (134 aa) |
| | ENSMODP00000056797 | Uncharacterized protein. (566 aa) |
| | CDCA8 | Cell division cycle associated 8. (312 aa) |
| | CCDC124 | HMG box domain-containing protein. (221 aa) |
| | ENSMODP00000057879 | Uncharacterized protein. (207 aa) |
| | CTNND1 | Catenin delta 1. (965 aa) |
| | ECT2 | Epithelial cell transforming 2. (912 aa) |
| | RALA | Uncharacterized protein. (501 aa) |
| | PIN1 | Peptidyl-prolyl cis-trans isomerase. (242 aa) |
| | ZFYVE19 | Zinc finger FYVE-type containing 19. (440 aa) |
| | TXNDC9 | Thioredoxin domain containing 9. (266 aa) |
| | CCDC69 | Uncharacterized protein. (297 aa) |
| | RACGAP1 | Rac GTPase activating protein 1. (608 aa) |
| | MAP11 | Microtubule associated protein 11. (568 aa) |
| | ARL8B | ADP ribosylation factor like GTPase 8B; Belongs to the small GTPase superfamily. Arf family. (150 aa) |
| | FLCN | UDENN FLCN/SMCR8-type domain-containing protein. (579 aa) |
| | KIF4A | Kinesin family member 4A; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1235 aa) |
| | APC2 | APC_N_CC domain-containing protein. (1586 aa) |
| | VPS4B | Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (459 aa) |
| | KEAP1 | Kelch like ECH associated protein 1. (623 aa) |
| | CEP55 | Centrosomal protein 55. (408 aa) |
| | SEPTIN12 | Septin 12; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (356 aa) |
| | CHMP4C | Charged multivesicular body protein 4C. (232 aa) |
| | SCCPDH | Saccharopine dehydrogenase (putative). (441 aa) |
| | TSG101 | Uncharacterized protein. (391 aa) |
| | EXOC6 | Exocyst complex component; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (814 aa) |
| | HNRNPU | Heterogeneous nuclear ribonucleoprotein U. (837 aa) |
| | PLK1 | Serine/threonine-protein kinase PLK. (614 aa) |
| | GEM | GTP-binding protein; Belongs to the small GTPase superfamily. RGK family. (296 aa) |
| | EXOC5 | Exocyst complex component 5. (650 aa) |
| | EXOC7 | Exocyst complex component 7; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. (707 aa) |
| | EXOC2 | Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (921 aa) |
| | F6PHC7_MONDO | HPHLAWLY domain-containing protein. (865 aa) |
| | CHMP7 | Charged multivesicular body protein 7. (453 aa) |
| | KIF23 | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (949 aa) |
| | DCDC5 | Ricin B-type lectin domain-containing protein. (808 aa) |
| | NAT10 | RNA cytidine acetyltransferase; RNA cytidine acetyltransferase with specificity toward both 18S rRNA and tRNAs. Catalyzes the formation of N(4)-acetylcytidine (ac4C) in 18S rRNA. Required for early nucleolar cleavages of precursor rRNA at sites A0, A1 and A2 during 18S rRNA synthesis. Catalyzes the formation of ac4C in serine and leucine tRNAs. Requires the tRNA- binding adapter protein THUMPD1 for full tRNA acetyltransferase activity but not for 18S rRNA acetylation. (1027 aa) |
| | SPART | Spartin. (670 aa) |
| | ZFYVE26 | Uncharacterized protein. (321 aa) |
| | SEPTIN5 | Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (350 aa) |
| | SEPTIN6 | Septin 6; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (351 aa) |
| | ERH | ERH mRNA splicing and mitosis factor. (147 aa) |
| | DTNBP1 | Dystrobrevin binding protein 1. (346 aa) |
| | ENTR1 | Uncharacterized protein. (356 aa) |
| | MICAL1 | Microtubule associated monooxygenase, calponin and LIM domain containing 1. (869 aa) |
| | DDX11 | DEAD/H-box helicase 11. (901 aa) |
| | RAB11FIP4 | RAB11 family interacting protein 4. (635 aa) |
| | POLDIP2 | DNA polymerase delta interacting protein 2. (367 aa) |
| | IL16 | Pro-interleukin-16; Interleukin-16 stimulates a migratory response in CD4+ lymphocytes, monocytes, and eosinophils. Primes CD4+ T-cells for IL-2 and IL-15 responsiveness. Also induces T-lymphocyte expression of interleukin 2 receptor. Ligand for CD4. (1474 aa) |
| | HSPA5 | Heat shock protein family A (Hsp70) member 5; Belongs to the heat shock protein 70 family. (657 aa) |
| | TTC23L | Uncharacterized protein. (584 aa) |
| | TBCK | TBC1 domain containing kinase. (893 aa) |
| | CENPC | Uncharacterized protein. (1012 aa) |
| | PSRC1 | Proline and serine rich coiled-coil 1. (319 aa) |
| | TTC28 | TPR_REGION domain-containing protein. (1246 aa) |
| | WIZ | Uncharacterized protein. (1881 aa) |
| | ARF6 | ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa) |
| | CDC42 | Cell division cycle 42. (191 aa) |
| | F7CI75_MONDO | Uncharacterized protein. (223 aa) |
| | MPLKIP | M-phase specific PLK1 interacting protein. (168 aa) |
| | INCENP | Inner centromere protein. (909 aa) |
| | CRMP1 | Collapsin response mediator protein 1. (686 aa) |
| | ARL3 | Uncharacterized protein. (388 aa) |
| | KIF20B | Kinesin family member 20B; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1850 aa) |
| | CPEB3 | Cytoplasmic polyadenylation element binding protein 3. (739 aa) |
| | ANXA11 | Annexin. (445 aa) |
| | F7FXR0_MONDO | Kinesin motor domain-containing protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (2679 aa) |
| | LOC100013717 | Uncharacterized protein. (198 aa) |
| | F6U2S4_MONDO | Deacetylase sirtuin-type domain-containing protein. (261 aa) |
| | MDP1 | Uncharacterized protein. (160 aa) |
| | LOC100012228 | ANK_REP_REGION domain-containing protein. (319 aa) |
| | SH3GLB1 | SH3 domain containing GRB2 like, endophilin B1. (402 aa) |
| | HSP90B1 | Heat shock protein 90 beta family member 1. (835 aa) |
| | BIRC5 | Uncharacterized protein. (127 aa) |
| | GNAI2 | G protein subunit alpha i2. (315 aa) |
| | MICAL3 | Uncharacterized protein. (1071 aa) |
| | MAK | Male germ cell associated kinase. (596 aa) |
| | VPS37B | VPS37B subunit of ESCRT-I. (287 aa) |
| | LYRM1 | Uncharacterized protein; Belongs to the complex I LYR family. (194 aa) |
| | MITD1 | Microtubule interacting and trafficking domain containing 1. (249 aa) |
| | SEPT1 | Septin-type G domain-containing protein; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (85 aa) |
| | PRC1 | Uncharacterized protein. (624 aa) |
| | ANKRD54 | ANK_REP_REGION domain-containing protein. (292 aa) |
| | PIK3C3 | Phosphatidylinositol 3-kinase catalytic subunit type 3. (887 aa) |
| | CEP126 | Uncharacterized protein. (1122 aa) |
| | ENSMODP00000046282 | BMERB domain-containing protein. (91 aa) |
| | LOC100020945 | Uncharacterized protein. (257 aa) |
| | C6orf89 | Chromosome 6 open reading frame 89. (391 aa) |
| | ENSMODP00000047212 | Annexin. (124 aa) |
| | CHMP6 | Uncharacterized protein. (201 aa) |
| | DCTN3 | Dynactin subunit 3. (203 aa) |
| | PDXP | Pyridoxal phosphatase. (333 aa) |
| | ANKRD45 | ANK_REP_REGION domain-containing protein. (272 aa) |
| | ARL2BP | ADP ribosylation factor like GTPase 2 binding protein. (240 aa) |
| | SHCBP1 | SHC binding and spindle associated 1. (762 aa) |
| | LOC100029547 | Uncharacterized protein; Belongs to the complex I LYR family. (122 aa) |
| | PKN2 | Protein kinase N2. (1013 aa) |
| | CAPG | Capping actin protein, gelsolin like. (424 aa) |
| | CHMP3 | Uncharacterized protein. (223 aa) |
| | F6X603_MONDO | Uncharacterized protein. (340 aa) |
| | C9orf72 | C9orf72-SMCR8 complex subunit. (481 aa) |
| | RACK1 | Receptor for activated C kinase 1. (317 aa) |
| | CEP44 | CEP44 domain-containing protein. (481 aa) |
| | F7EG17_MONDO | Uncharacterized protein. (2773 aa) |
| | CHMP4A | Charged multivesicular body protein 4A. (221 aa) |
| | VPS4A | Uncharacterized protein; Belongs to the AAA ATPase family. (587 aa) |
| | NEK2 | NIMA related kinase 2. (445 aa) |
| | PTCH1 | Patched 1. (1521 aa) |
| | PKN1 | Protein kinase N1. (956 aa) |
| | F7BW97_MONDO | BRO1 domain-containing protein. (854 aa) |
| | IST1 | IST1 factor associated with ESCRT-III. (371 aa) |
| | USP8 | Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (1102 aa) |
| | USP50 | Ubiquitin specific peptidase 50; Belongs to the peptidase C19 family. (370 aa) |
| | GNAI3 | G protein subunit alpha i3. (399 aa) |
| | KLHDC8A | Kelch domain containing 8A. (361 aa) |
| | KATNBL1 | Katanin regulatory subunit B1 like 1. (303 aa) |
| | LAP3 | Leucine aminopeptidase 3. (530 aa) |
| | EXOC3 | Exocyst complex component 3. (745 aa) |
| | ARL8A | ADP ribosylation factor like GTPase 8A; Belongs to the small GTPase superfamily. Arf family. (172 aa) |
| | RALB | RAS like proto-oncogene B. (206 aa) |
| | USP3 | Ubiquitin carboxyl-terminal hydrolase; Deubiquitinating enzyme that removes conjugated ubiquitin from specific proteins to regulate different cellular processes. Belongs to the peptidase C19 family. (520 aa) |
| | F6SQ78_MONDO | GFA domain-containing protein. (257 aa) |
| | GNL3 | G protein nucleolar 3. (544 aa) |
| | RASGEF1B | RasGEF domain family member 1B. (431 aa) |
| | LZTS2 | Leucine zipper putative tumor suppressor 2; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta- catenin. (758 aa) |
| | CTDP1 | CTD phosphatase subunit 1. (1047 aa) |
| | KIF20A | Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (894 aa) |
| | KIF14 | Kinesin family member 14; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1710 aa) |
| | KLHDC8B | Kelch domain containing 8B. (354 aa) |
| | CLIC4 | Chloride intracellular channel protein; Belongs to the chloride channel CLIC family. (242 aa) |
| | KATNB1 | Katanin p80 WD40 repeat-containing subunit B1; Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Micr [...] (643 aa) |
| | F6T9J4_MONDO | Uncharacterized protein. (191 aa) |
| | F6T6R5_MONDO | CS domain-containing protein. (209 aa) |
| | EXOC4 | Exocyst complex component 4. (975 aa) |
| | CIT | Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2039 aa) |
| | BIRC6 | Baculoviral IAP repeat containing 6. (4876 aa) |
| | YPEL5 | Protein yippee-like; Belongs to the yippee family. (121 aa) |
| | SEPTIN2 | Septin 2; Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Septin GTPase family. (366 aa) |
| | RAB11FIP3 | RAB11 family interacting protein 3. (933 aa) |
| | KATNA1 | Katanin p60 ATPase-containing subunit A1; Catalytic subunit of a complex which severs microtubules in an ATP-dependent manner. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal p [...] (514 aa) |
| | CHMP2B | Charged multivesicular body protein 2B. (214 aa) |
| | F6V3Z4_MONDO | Protein kinase domain-containing protein. (284 aa) |
| | EML4 | EMAP like 4. (1025 aa) |
| | TEX14 | Protein kinase domain-containing protein. (1301 aa) |
