STRINGSTRING
F11R F11R ROCK2 ROCK2 LOC100013657 LOC100013657 ESRP1 ESRP1 ROCK1 ROCK1 ENSMODP00000054835 ENSMODP00000054835 AHI1 AHI1 PRKX PRKX CLDN5 CLDN5 SPRY1 SPRY1 PROM1 PROM1 ADD1 ADD1 DLL1 DLL1 CCND1 CCND1 XDH XDH HOXA7 HOXA7 VCL VCL ATOH8 ATOH8 GDF2 GDF2 SERPINE1 SERPINE1 ENSMODP00000045775 ENSMODP00000045775 MACROH2A2 MACROH2A2 BAD BAD SPRED2 SPRED2 ETV2 ETV2 YAP1 YAP1 ENSMODP00000042313 ENSMODP00000042313 MACROH2A1 MACROH2A1 WNT9B WNT9B VDR VDR K7E0A4_MONDO K7E0A4_MONDO ZBED3 ZBED3 APOLD1 APOLD1 PAX6 PAX6 TMEM100 TMEM100 EZH2 EZH2 SPRED1 SPRED1 ZEB1 ZEB1 SFN SFN NOTCH4 NOTCH4 JAG1 JAG1 CDH5 CDH5 CYP27B1 CYP27B1 WWTR1 WWTR1 GDNF GDNF LOC100015455 LOC100015455 ID1 ID1 FST FST ATOH1 ATOH1 FOXN1 FOXN1 FGF2 FGF2 MAFF MAFF CYP27C1 CYP27C1 PROC PROC CDKN1B CDKN1B TNFRSF1A TNFRSF1A FOXJ2 FOXJ2 GATA3 GATA3 LOC100030262 LOC100030262 CEBPB CEBPB NCOA3 NCOA3 KLF7 KLF7 CAV1 CAV1 TNF TNF RFX3 RFX3 ETV4 ETV4 TP63 TP63 ZDHHC21 ZDHHC21 LOC100012174 LOC100012174 NOG NOG LOC100011470 LOC100011470 GRHL1 GRHL1 SMO SMO KRT36 KRT36 KDF1 KDF1 IL1B IL1B MMP9 MMP9 S1PR3 S1PR3 BMP4 BMP4 MED1 MED1 SFRP4 SFRP4 NFE2L1 NFE2L1 NODAL NODAL STAT1 STAT1 CTNNB1 CTNNB1 OSR1 OSR1 FRZB FRZB NKX6-3 NKX6-3 IKBKB IKBKB BMP6 BMP6 ERRFI1 ERRFI1 BTG1 BTG1 LIF LIF FOXJ1 FOXJ1 TRIM16 TRIM16 AJAP1 AJAP1 GRHL2 GRHL2 KEAP1 KEAP1 PLCB1 PLCB1 F6VW21_MONDO F6VW21_MONDO BMP2 BMP2 MAFG MAFG PTCH1 PTCH1 PTCH2 PTCH2 F6YRI3_MONDO F6YRI3_MONDO
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
F11RUncharacterized protein. (342 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1482 aa)
LOC100013657Uncharacterized protein. (332 aa)
ESRP1Epithelial splicing regulatory protein 1. (728 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1322 aa)
ENSMODP00000054835Uncharacterized protein. (83 aa)
AHI1Abelson helper integration site 1. (1237 aa)
PRKXUncharacterized protein. (419 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
SPRY1Uncharacterized protein. (105 aa)
PROM1Prominin 1. (875 aa)
ADD1Adducin 1. (780 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (734 aa)
CCND1Uncharacterized protein. (67 aa)
XDHXanthine dehydrogenase. (1258 aa)
HOXA7Homeobox domain-containing protein. (226 aa)
VCLVinculin. (1147 aa)
ATOH8BHLH domain-containing protein. (328 aa)
GDF2TGF_BETA_2 domain-containing protein. (427 aa)
SERPINE1Serpin family E member 1; Belongs to the serpin family. (413 aa)
ENSMODP00000045775SAM domain-containing protein. (300 aa)
MACROH2A2H2A histone family member Y2. (347 aa)
BADUncharacterized protein. (212 aa)
SPRED2Sprouty related EVH1 domain containing 2. (419 aa)
ETV2ETS domain-containing protein. (294 aa)
YAP1Yes associated protein 1. (512 aa)
ENSMODP00000042313Uncharacterized protein. (84 aa)
MACROH2A1H2A histone family member Y. (406 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (427 aa)
VDRUncharacterized protein. (289 aa)
K7E0A4_MONDOUncharacterized protein. (667 aa)
ZBED3BED-type domain-containing protein. (234 aa)
APOLD1Apolipoprotein L domain containing 1. (300 aa)
PAX6Paired box 6. (221 aa)
TMEM100Transmembrane protein 100. (114 aa)
EZH2Uncharacterized protein. (665 aa)
SPRED1Sprouty related EVH1 domain containing 1. (448 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1116 aa)
SFNStratifin; Belongs to the 14-3-3 family. (256 aa)
NOTCH4Uncharacterized protein. (1975 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1276 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (722 aa)
CYP27B1Cytochrome P450 family 27 subfamily B member 1; Belongs to the cytochrome P450 family. (516 aa)
WWTR1WW domain containing transcription regulator 1. (413 aa)
GDNFGlial cell derived neurotrophic factor. (183 aa)
LOC100015455BHLH domain-containing protein. (262 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (150 aa)
FSTFollistatin. (343 aa)
ATOH1Atonal bHLH transcription factor 1. (380 aa)
FOXN1Forkhead box N1. (636 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (156 aa)
MAFFMAF bZIP transcription factor F. (157 aa)
CYP27C1Cytochrome P450 family 27 subfamily C member 1; Belongs to the cytochrome P450 family. (372 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa. (460 aa)
CDKN1BP27 protein. (199 aa)
TNFRSF1AUncharacterized protein. (453 aa)
FOXJ2Forkhead box J2. (561 aa)
GATA3GATA binding protein 3. (444 aa)
LOC100030262Anti_prolifrtn domain-containing protein. (151 aa)
CEBPBCCAAT enhancer binding protein beta. (364 aa)
NCOA3Nuclear receptor coactivator. (1400 aa)
KLF7Kruppel like factor 7. (302 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (229 aa)
RFX3Regulatory factor X3. (753 aa)
ETV4ETS variant 4. (478 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
LOC100012174Signal transducer and activator of transcription. (782 aa)
NOGNoggin; Inhibitor of bone morphogenetic proteins (BMP) signaling which is required for growth and patterning of the neural tube and somite. (232 aa)
LOC100011470Signal transducer and activator of transcription. (839 aa)
GRHL1Grainyhead like transcription factor 1. (571 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (785 aa)
KRT36Keratin 36; Belongs to the intermediate filament family. (462 aa)
KDF1Keratinocyte differentiation factor 1. (415 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
MMP9Matrix metallopeptidase 9. (709 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (380 aa)
BMP4Bone morphogenetic protein 4. (410 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1609 aa)
SFRP4Secreted frizzled related protein 4. (348 aa)
NFE2L1Nuclear factor, erythroid 2 like 1. (737 aa)
NODALNodal growth differentiation factor. (347 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
CTNNB1Catenin beta 1. (781 aa)
OSR1Odd-skipped related transcription factor 1. (265 aa)
FRZBFrizzled related protein. (321 aa)
NKX6-3Homeobox domain-containing protein. (262 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (693 aa)
BMP6Bone morphogenetic protein 6. (534 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (469 aa)
BTG1BTG anti-proliferation factor 1. (169 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
FOXJ1Forkhead box J1. (418 aa)
TRIM16Uncharacterized protein. (553 aa)
AJAP1Adherens junctions associated protein 1. (404 aa)
GRHL2Grainyhead like transcription factor 2. (624 aa)
KEAP1Kelch like ECH associated protein 1. (623 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
F6VW21_MONDOCyclin_C domain-containing protein. (89 aa)
BMP2Bone morphogenetic protein 2. (436 aa)
MAFGMAF bZIP transcription factor G. (162 aa)
PTCH1Patched 1. (1521 aa)
PTCH2Patched 2. (992 aa)
F6YRI3_MONDOUncharacterized protein. (647 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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