35 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRPM2	LSDAT_euk domain-containing protein. (860 aa)
	HNF1A	HNF1 homeobox A. (613 aa)
	CAPN10	Calpain 10; Belongs to the peptidase C2 family. (676 aa)
	NLGN2	COesterase domain-containing protein. (324 aa)
	RFX6	Regulatory factor X6. (930 aa)
	TM7SF3	Transmembrane 7 superfamily member 3. (572 aa)
	BAIAP3	BAI1 associated protein 3. (1048 aa)
	CFTR	Cystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1481 aa)
	AACS	Acetoacetyl-CoA synthetase. (672 aa)
	NR0B2	Nuclear receptor subfamily 0 group B member 2. (293 aa)
	FFAR1	Free fatty acid receptor 1. (299 aa)
	BLK	Tyrosine-protein kinase. (501 aa)
	SRI	Sorcin. (234 aa)
	PDX1	Homeobox domain-containing protein. (290 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (830 aa)
	ADCY8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1254 aa)
	LRRC8A	Leucine rich repeat containing 8 VRAC subunit A. (999 aa)
	MPC2	Mitochondrial pyruvate carrier; Mediates the uptake of pyruvate into mitochondria. Belongs to the mitochondrial pyruvate carrier (MPC) (TC 2.A.105) family. (119 aa)
	ACSL4	Acyl-CoA synthetase long chain family member 4. (788 aa)
	GPR68	G protein-coupled receptor 68; Belongs to the G-protein coupled receptor 1 family. (344 aa)
	NR1H4	Nuclear receptor subfamily 1 group H member 4. (481 aa)
	TRH	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems. (232 aa)
	GHRL	Uncharacterized protein. (132 aa)
	TUNAR	TCL1 upstream neural differentiation-associated RNA. (48 aa)
	TCF7L2	Transcription factor 7 like 2. (579 aa)
	PCK2	Phosphoenolpyruvate carboxykinase 2, mitochondrial. (553 aa)
	MCU	Mitochondrial calcium uniporter. (353 aa)
	C2CD2L	C2CD2 like. (712 aa)
	GPLD1	Glycosylphosphatidylinositol specific phospholipase D1. (900 aa)
	GCK	Phosphotransferase. (532 aa)
	PLA2G6	Phospholipase A2 group VI. (818 aa)
	RPH3AL	Rabphilin 3A like (without C2 domains). (312 aa)
	BAD	Uncharacterized protein. (212 aa)
	PSMD9	Uncharacterized protein. (228 aa)
	STX4	Syntaxin 4; Belongs to the syntaxin family. (297 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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structured XML interaction data, according to the 'PSI-MI' data standard

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CAPN10	SRI	ENSMODP00000003278	ENSMODP00000012974	Calpain 10; Belongs to the peptidase C2 family.	Sorcin.	0.410
GCK	HNF1A	ENSMODP00000048190	ENSMODP00000003604	Phosphotransferase.	HNF1 homeobox A.	0.573
GCK	PDX1	ENSMODP00000048190	ENSMODP00000011240	Phosphotransferase.	Homeobox domain-containing protein.	0.686
GHRL	TCF7L2	ENSMODP00000055808	ENSMODP00000052962	Uncharacterized protein.	Transcription factor 7 like 2.	0.404
GHRL	TRH	ENSMODP00000055808	ENSMODP00000058056	Uncharacterized protein.	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.	0.653
HNF1A	GCK	ENSMODP00000003604	ENSMODP00000048190	HNF1 homeobox A.	Phosphotransferase.	0.573
HNF1A	PDX1	ENSMODP00000003604	ENSMODP00000011240	HNF1 homeobox A.	Homeobox domain-containing protein.	0.459
NR0B2	NR1H4	ENSMODP00000018027	ENSMODP00000059402	Nuclear receptor subfamily 0 group B member 2.	Nuclear receptor subfamily 1 group H member 4.	0.767
NR1H4	NR0B2	ENSMODP00000059402	ENSMODP00000018027	Nuclear receptor subfamily 1 group H member 4.	Nuclear receptor subfamily 0 group B member 2.	0.767
PDX1	GCK	ENSMODP00000011240	ENSMODP00000048190	Homeobox domain-containing protein.	Phosphotransferase.	0.686
PDX1	HNF1A	ENSMODP00000011240	ENSMODP00000003604	Homeobox domain-containing protein.	HNF1 homeobox A.	0.459
SRI	CAPN10	ENSMODP00000012974	ENSMODP00000003278	Sorcin.	Calpain 10; Belongs to the peptidase C2 family.	0.410
TCF7L2	GHRL	ENSMODP00000052962	ENSMODP00000055808	Transcription factor 7 like 2.	Uncharacterized protein.	0.404
TRH	GHRL	ENSMODP00000058056	ENSMODP00000055808	Pro-thyrotropin-releasing hormone; Functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.	Uncharacterized protein.	0.653