STRINGSTRING
CTNNB1 CTNNB1 MED8 MED8 CDC73 CDC73 CDK13 CDK13 BRD4 BRD4 ELL ELL CCNK CCNK EAPP EAPP ELL3 ELL3 SUPT6H SUPT6H ELL2 ELL2 F6RQE0_MONDO F6RQE0_MONDO CCNT2 CCNT2 CDK9 CDK9 ENSMODP00000056929 ENSMODP00000056929 ENSMODP00000055602 ENSMODP00000055602 CDK12 CDK12 ENSMODP00000049180 ENSMODP00000049180 MED8-2 MED8-2 ENSMODP00000042001 ENSMODP00000042001 CCNT1 CCNT1 F6WG96_MONDO F6WG96_MONDO GTF2F1 GTF2F1 LEO1 LEO1 SUPT16H SUPT16H PWWP2A PWWP2A
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CTNNB1Catenin beta 1. (781 aa)
MED8Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (287 aa)
CDC73CDC73_N domain-containing protein. (371 aa)
CDK13Cyclin dependent kinase 13. (1378 aa)
BRD4Uncharacterized protein. (692 aa)
ELLElongation factor for RNA polymerase II. (629 aa)
CCNKCyclin K; Belongs to the cyclin family. (580 aa)
EAPPE2F associated phosphoprotein. (284 aa)
ELL3Elongation factor for RNA polymerase II 3. (385 aa)
SUPT6HTranscription elongation factor spt6; Transcription elongation factor that enhances transcription elongation by RNA polymerase II (RNAPII). Belongs to the SPT6 family. (1726 aa)
ELL2Elongation factor for RNA polymerase II 2. (647 aa)
F6RQE0_MONDOChromo domain-containing protein. (148 aa)
CCNT2Uncharacterized protein; Belongs to the cyclin family. (731 aa)
CDK9Cyclin dependent kinase 9. (508 aa)
ENSMODP00000056929CYCLIN domain-containing protein; Belongs to the cyclin family. (172 aa)
ENSMODP00000055602Uncharacterized protein. (451 aa)
CDK12Protein kinase domain-containing protein. (1499 aa)
ENSMODP00000049180Protein kinase domain-containing protein. (266 aa)
MED8-2Mediator of RNA polymerase II transcription subunit 8; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (136 aa)
ENSMODP00000042001MARVEL domain-containing protein. (493 aa)
CCNT1Cyclin T1. (590 aa)
F6WG96_MONDOTranscription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (243 aa)
GTF2F1Transcription initiation factor IIF subunit alpha; TFIIF is a general transcription initiation factor that binds to RNA polymerase II and helps to recruit it to the initiation complex in collaboration with TFIIB. It promotes transcription elongation. Belongs to the TFIIF alpha subunit family. (243 aa)
LEO1LEO1 homolog, Paf1/RNA polymerase II complex component. (668 aa)
SUPT16HSPT16 homolog, facilitates chromatin remodeling subunit. (1047 aa)
PWWP2APWWP domain containing 2A. (602 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
Server load: low (32%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.