STRINGSTRING
OSR1 OSR1 MSX1 MSX1 ALX3 ALX3 FGF4 FGF4 RSPO2 RSPO2 CHD7 CHD7 CTNNB1 CTNNB1 MED1 MED1 ZBTB16 ZBTB16 TBX4 TBX4 TP63 TP63 GPC3 GPC3 ALX4 ALX4 RPGRIP1L RPGRIP1L PITX1 PITX1 PITX2 PITX2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
OSR1Odd-skipped related transcription factor 1. (265 aa)
MSX1Msh homeobox 1. (314 aa)
ALX3ALX homeobox 3. (336 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (192 aa)
RSPO2R-spondin 2. (243 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2999 aa)
CTNNB1Catenin beta 1. (781 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1609 aa)
ZBTB16Zinc finger and BTB domain containing 16. (674 aa)
TBX4T-box transcription factor 4. (515 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (486 aa)
ALX4ALX homeobox 4. (417 aa)
RPGRIP1LRPGRIP1 like. (1268 aa)
PITX1Homeobox protein. (306 aa)
PITX2Homeobox domain-containing protein. (273 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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