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IRAK3 | Interleukin 1 receptor associated kinase 3. (591 aa) | ||||
FLT1 | Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1341 aa) | ||||
AGT | Angiotensinogen; Belongs to the serpin family. (469 aa) | ||||
MAP2K5 | Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa) | ||||
PDGFB | Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (235 aa) | ||||
HIPK3 | Homeodomain interacting protein kinase 3. (1247 aa) | ||||
TRIB2 | Tribbles pseudokinase 2. (343 aa) | ||||
EDN1 | Endothelin 1. (214 aa) | ||||
PRKCD | Protein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa) | ||||
HTR2B | 5-hydroxytryptamine receptor 2B; Belongs to the G-protein coupled receptor 1 family. (473 aa) | ||||
DTNBP1 | Dystrobrevin binding protein 1. (346 aa) | ||||
TGFA | Transforming growth factor alpha. (159 aa) | ||||
IRAK1 | Interleukin 1 receptor associated kinase 1. (685 aa) | ||||
P2RX7 | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa) | ||||
CDK5RAP3 | CDK5 regulatory subunit associated protein 3. (506 aa) | ||||
PTPRC | Protein tyrosine phosphatase receptor type C. (1142 aa) | ||||
BMP4 | Bone morphogenetic protein 4. (410 aa) | ||||
SORL1 | Sortilin related receptor 1. (2218 aa) | ||||
NOD2 | Nucleotide binding oligomerization domain containing 2. (1012 aa) | ||||
ADIPOQ | Adiponectin, C1Q and collagen domain containing. (256 aa) | ||||
FGD2 | FYVE, RhoGEF and PH domain containing 2. (618 aa) | ||||
IL1B | Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa) | ||||
IL34 | Uncharacterized protein. (279 aa) | ||||
TNFSF11 | Tumor necrosis factor ligand superfamily member. (317 aa) | ||||
AGER | Advanced glycosylation end-product specific receptor. (406 aa) | ||||
DUSP10 | Dual specificity phosphatase 10. (482 aa) | ||||
F6WK84_MONDO | Uncharacterized protein. (294 aa) | ||||
TNFRSF11A | TNFR-Cys domain-containing protein. (670 aa) | ||||
TSG101 | Uncharacterized protein. (391 aa) | ||||
TENM1 | Teneurin transmembrane protein 1. (2741 aa) | ||||
TNXB | Tenascin XB. (536 aa) | ||||
MAP2K7 | Mitogen-activated protein kinase kinase 7. (546 aa) | ||||
NEK10 | NIMA related kinase 10. (1091 aa) | ||||
INSR | Tyrosine-protein kinase receptor. (1378 aa) | ||||
TNF | Tumor necrosis factor; Belongs to the tumor necrosis factor family. (229 aa) | ||||
CAV1 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa) | ||||
PTK2B | Protein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (984 aa) | ||||
FZD5 | Frizzled class receptor 5; Belongs to the G-protein coupled receptor Fz/Smo family. (592 aa) | ||||
PTPN1 | Tyrosine-protein phosphatase non-receptor type. (391 aa) | ||||
PIK3CG | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1099 aa) | ||||
DKK1 | Dickkopf WNT signaling pathway inhibitor 1. (289 aa) | ||||
SASH1 | Uncharacterized protein. (648 aa) | ||||
GBA | Glucosylceramidase. (535 aa) | ||||
MAP3K5 | Mitogen-activated protein kinase kinase kinase 5. (1390 aa) | ||||
PTPN6 | Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa) | ||||
DUSP16 | Dual specificity phosphatase 16. (660 aa) | ||||
LRRK2 | Leucine rich repeat kinase 2. (2527 aa) | ||||
SMPD1 | Sphingomyelin phosphodiesterase; Converts sphingomyelin to ceramide. (625 aa) | ||||
FGF2 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (156 aa) | ||||
VEGFA | Vascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (445 aa) | ||||
ROR2 | Receptor tyrosine kinase like orphan receptor 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (943 aa) | ||||
TRAF6 | TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa) | ||||
TRIB3 | Protein kinase domain-containing protein. (146 aa) | ||||
THBS1 | Thrombospondin 1. (1197 aa) | ||||
MAP3K4 | Mitogen-activated protein kinase kinase kinase 4. (1621 aa) | ||||
TPD52L1 | TPD52 like 1. (214 aa) | ||||
INPP5K | Inositol polyphosphate-5-phosphatase K. (465 aa) | ||||
MAP3K11 | Mitogen-activated protein kinase kinase kinase. (859 aa) | ||||
ENSMODP00000042313 | Uncharacterized protein. (84 aa) | ||||
MAP3K7 | Mitogen-activated protein kinase kinase kinase 7; Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily. (607 aa) | ||||
SH2B3 | SH2 domain-containing protein. (458 aa) | ||||
FGF1 | Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (181 aa) | ||||
ENSMODP00000049462 | Uncharacterized protein. (802 aa) | ||||
RASGRP1 | RAS guanyl releasing protein 1. (861 aa) | ||||
CAV3 | Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (242 aa) | ||||
MAPK8IP1 | Mitogen-activated protein kinase 8 interacting protein 1. (646 aa) | ||||
ENSMODP00000052422 | UEV domain-containing protein. (123 aa) | ||||
SPRY1 | Uncharacterized protein. (105 aa) | ||||
DAB2IP | DAB2 interacting protein. (1180 aa) | ||||
EPGN | EGF-like domain-containing protein. (152 aa) | ||||
PIK3CB | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1074 aa) | ||||
ENSMODP00000053548 | Aida_C2 domain-containing protein. (130 aa) | ||||
DUSP19 | Uncharacterized protein; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (202 aa) | ||||
ENSMODP00000053960 | KH type-2 domain-containing protein. (115 aa) | ||||
ENSMODP00000054835 | Uncharacterized protein. (83 aa) | ||||
SYK | Tyrosine-protein kinase. (588 aa) | ||||
F6TN87_MONDO | Uncharacterized protein. (519 aa) | ||||
SPRY2 | Sprouty RTK signaling antagonist 2. (317 aa) | ||||
SFRP2 | Secreted frizzled related protein 2. (295 aa) | ||||
F6YRI3_MONDO | Uncharacterized protein. (647 aa) | ||||
ENSMODP00000056005 | Sema domain-containing protein. (996 aa) | ||||
ENSMODP00000056713 | Aida_C2 domain-containing protein. (130 aa) | ||||
FGF18 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (223 aa) | ||||
NF1 | Neurofibromin 1. (2781 aa) | ||||
LYN | Tyrosine-protein kinase. (516 aa) | ||||
APOE | Uncharacterized protein. (299 aa) | ||||
ARHGEF5 | ARHGEF5_35 domain-containing protein. (1125 aa) | ||||
PSEN1 | Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (516 aa) | ||||
NTF3 | Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (343 aa) | ||||
KSR1 | Kinase suppressor of ras 1. (918 aa) | ||||
UCHL1 | Ubiquitin carboxyl-terminal hydrolase isozyme L1; Ubiquitin-protein hydrolase involved both in the processing of ubiquitin precursors and of ubiquitinated proteins. This enzyme is a thiol protease that recognizes and hydrolyzes a peptide bond at the C- terminal glycine of ubiquitin (By similarity). Also binds to free monoubiquitin and may prevent its degradation in lysosomes (By similarity). The homodimer may have ATP-independent ubiquitin ligase activity (By similarity); Belongs to the peptidase C12 family. (223 aa) | ||||
PAQR3 | Progestin and adipoQ receptor family member 3. (311 aa) | ||||
LOC100017469 | Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1570 aa) | ||||
F6TPY2_MONDO | Uncharacterized protein. (272 aa) | ||||
SPRY4 | Sprouty RTK signaling antagonist 4. (300 aa) | ||||
EZH2 | Uncharacterized protein. (665 aa) | ||||
F7GFS5_MONDO | Uncharacterized protein. (1113 aa) | ||||
PDCD10 | Uncharacterized protein. (149 aa) | ||||
AKAP13 | Uncharacterized protein. (1424 aa) | ||||
NTRK3 | Tyrosine-protein kinase receptor. (850 aa) | ||||
ERN2 | Endoplasmic reticulum to nucleus signaling 2. (880 aa) | ||||
KIT | Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (967 aa) | ||||
SPRY3 | Uncharacterized protein. (109 aa) | ||||
CCL19 | C-C motif chemokine. (96 aa) | ||||
F6XW95_MONDO | P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (567 aa) | ||||
LAX1 | Uncharacterized protein. (410 aa) | ||||
K7E0A4_MONDO | Uncharacterized protein. (667 aa) | ||||
CBLC | Cbl-PTB domain-containing protein. (416 aa) | ||||
LOC103093164 | Ig-like domain-containing protein. (298 aa) | ||||
K7E532_MONDO | Uncharacterized protein. (151 aa) | ||||
ENSMODP00000041408 | Uncharacterized protein. (134 aa) | ||||
AXIN1 | Axin 1. (875 aa) | ||||
AJUBA | Ajuba LIM protein. (537 aa) | ||||
LIME1 | Uncharacterized protein. (249 aa) | ||||
PDGFC | Platelet derived growth factor C. (345 aa) | ||||
TRIB1 | Tribbles pseudokinase 1. (369 aa) | ||||
DRD4 | G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (341 aa) | ||||
HMGCR | 3-hydroxy-3-methylglutaryl coenzyme A reductase. (907 aa) | ||||
F7CYW1_MONDO | Uncharacterized protein. (544 aa) | ||||
MAP3K13 | Mitogen-activated protein kinase kinase kinase. (964 aa) | ||||
NOX4 | NADPH oxidase 4. (578 aa) | ||||
HGS | Hepatocyte growth factor-regulated tyrosine kinase substrate; Involved in intracellular signal transduction mediated by cytokines and growth factors. When associated with STAM, it suppresses DNA signaling upon stimulation by IL-2 and GM-CSF. Could be a direct effector of PI3-kinase in vesicular pathway via early endosomes and may regulate trafficking to early and late endosomes by recruiting clathrin. May concentrate ubiquitinated receptors within clathrin- coated regions. Involved in down-regulation of receptor tyrosine kinase via multivesicular body (MVBs) when complexed with STAM (E [...] (779 aa) | ||||
ERP29 | Endoplasmic reticulum protein 29. (265 aa) | ||||
DVL3 | Dishevelled segment polarity protein 3. (635 aa) | ||||
BMP2 | Bone morphogenetic protein 2. (436 aa) | ||||
FZD4 | Frizzled class receptor 4; Belongs to the G-protein coupled receptor Fz/Smo family. (540 aa) | ||||
DVL2 | Dishevelled segment polarity protein 2. (731 aa) | ||||
FZD8 | Frizzled class receptor 8; Belongs to the G-protein coupled receptor Fz/Smo family. (710 aa) | ||||
RPS3 | KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa) | ||||
PIK3R5 | Phosphoinositide-3-kinase regulatory subunit 5. (873 aa) | ||||
TGFB1 | Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa) | ||||
SOS1 | SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa) | ||||
EGFR | Receptor protein-tyrosine kinase. (1213 aa) |