(37 nodes) Regulation of cellular respiration network (Monodelphis domestica)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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protein homology

Your Input:
	TRPV4	Transient receptor potential cation channel subfamily V member 4. (640 aa)
	IFNAR1	Uncharacterized protein. (565 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	F7CAM4_MONDO	Uncharacterized protein. (122 aa)
	NOP53	NOP53 ribosome biogenesis factor. (497 aa)
	PDE12	Phosphodiesterase 12. (633 aa)
	PARK7	DJ-1_PfpI domain-containing protein. (189 aa)
	MLXIPL	Uncharacterized protein. (260 aa)
	PINK1	Protein kinase domain-containing protein. (573 aa)
	DNAJC15	DnaJ heat shock protein family (Hsp40) member C15. (156 aa)
	ENSMODP00000046472	Uncharacterized protein. (65 aa)
	PRDM16	Uncharacterized protein. (143 aa)
	TRAP1	TNF receptor associated protein 1. (745 aa)
	F6U2Q2_MONDO	Uncharacterized protein. (116 aa)
	COX7A2L	Cytochrome c oxidase subunit 7A2 like. (114 aa)
	PPARGC1A	PPARG coactivator 1 alpha. (795 aa)
	PPIF	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (210 aa)
	AK4	Adenylate kinase 4, mitochondrial; Involved in maintaining the homeostasis of cellular nucleotides by catalyzing the interconversion of nucleoside phosphates. Efficiently phosphorylates AMP and dAMP using ATP as phosphate donor, but phosphorylates only AMP when using GTP as phosphate donor. Also displays broad nucleoside diphosphate kinase activity. (472 aa)
	FAM214A	Family with sequence similarity 214 member A. (1088 aa)
	PNPT1	Polyribonucleotide nucleotidyltransferase 1. (785 aa)
	LEXM	Uncharacterized protein. (437 aa)
	CBFA2T3	CBFA2/RUNX1 partner transcriptional co-repressor 3. (617 aa)
	FLCN	UDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
	F6W507_MONDO	PRELI/MSF1 domain-containing protein. (113 aa)
	PRELID1	PRELI/MSF1 domain-containing protein. (221 aa)
	IDE	Uncharacterized protein. (464 aa)
	OPN3	Opsin 3; Belongs to the G-protein coupled receptor 1 family. (526 aa)
	FAM214B	Family with sequence similarity 214 member B. (537 aa)
	VCP	Valosin containing protein; Belongs to the AAA ATPase family. (806 aa)
	ACTN3	Actinin alpha 3 (gene/pseudogene). (897 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (830 aa)
	ARL2	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (184 aa)
	IFNLR1	Fibronectin type-III domain-containing protein. (524 aa)
	UQCC2	Ubiquinol-cytochrome c reductase complex assembly factor 2. (126 aa)
	NUPR1	Uncharacterized protein. (82 aa)
	F7B3U4_MONDO	Uncharacterized protein. (108 aa)
	NOA1	Nitric oxide associated 1. (685 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARL2	PIK3CA	ENSMODP00000012766	ENSMODP00000026633	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	0.406
COX7A2L	ENSMODP00000046472	ENSMODP00000000405	ENSMODP00000046472	Cytochrome c oxidase subunit 7A2 like.	Uncharacterized protein.	0.433
COX7A2L	F6U2Q2_MONDO	ENSMODP00000000405	ENSMODP00000038373	Cytochrome c oxidase subunit 7A2 like.	Uncharacterized protein.	0.920
COX7A2L	F7B3U4_MONDO	ENSMODP00000000405	ENSMODP00000023072	Cytochrome c oxidase subunit 7A2 like.	Uncharacterized protein.	0.907
ENSMODP00000046472	COX7A2L	ENSMODP00000046472	ENSMODP00000000405	Uncharacterized protein.	Cytochrome c oxidase subunit 7A2 like.	0.433
ENSMODP00000046472	F6U2Q2_MONDO	ENSMODP00000046472	ENSMODP00000038373	Uncharacterized protein.	Uncharacterized protein.	0.475
F6U2Q2_MONDO	COX7A2L	ENSMODP00000038373	ENSMODP00000000405	Uncharacterized protein.	Cytochrome c oxidase subunit 7A2 like.	0.920
F6U2Q2_MONDO	ENSMODP00000046472	ENSMODP00000038373	ENSMODP00000046472	Uncharacterized protein.	Uncharacterized protein.	0.475
F6U2Q2_MONDO	F7B3U4_MONDO	ENSMODP00000038373	ENSMODP00000023072	Uncharacterized protein.	Uncharacterized protein.	0.918
F7B3U4_MONDO	COX7A2L	ENSMODP00000023072	ENSMODP00000000405	Uncharacterized protein.	Cytochrome c oxidase subunit 7A2 like.	0.907
F7B3U4_MONDO	F6U2Q2_MONDO	ENSMODP00000023072	ENSMODP00000038373	Uncharacterized protein.	Uncharacterized protein.	0.918
F7CAM4_MONDO	PPARGC1A	ENSMODP00000035006	ENSMODP00000000664	Uncharacterized protein.	PPARG coactivator 1 alpha.	0.539
HIF1A	PPARGC1A	ENSMODP00000010901	ENSMODP00000000664	Hypoxia inducible factor 1 subunit alpha.	PPARG coactivator 1 alpha.	0.403
IFNAR1	IFNLR1	ENSMODP00000026343	ENSMODP00000016333	Uncharacterized protein.	Fibronectin type-III domain-containing protein.	0.448
IFNLR1	IFNAR1	ENSMODP00000016333	ENSMODP00000026343	Fibronectin type-III domain-containing protein.	Uncharacterized protein.	0.448
NOA1	NOP53	ENSMODP00000025897	ENSMODP00000059850	Nitric oxide associated 1.	NOP53 ribosome biogenesis factor.	0.597
NOA1	PNPT1	ENSMODP00000025897	ENSMODP00000002420	Nitric oxide associated 1.	Polyribonucleotide nucleotidyltransferase 1.	0.720
NOP53	NOA1	ENSMODP00000059850	ENSMODP00000025897	NOP53 ribosome biogenesis factor.	Nitric oxide associated 1.	0.597
PARK7	PINK1	ENSMODP00000057855	ENSMODP00000053610	DJ-1_PfpI domain-containing protein.	Protein kinase domain-containing protein.	0.779
PIK3CA	ARL2	ENSMODP00000026633	ENSMODP00000012766	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit.	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family.	0.406