STRINGSTRING
TNF TNF ROCK2 ROCK2 ROCK1 ROCK1 F11R F11R CLDN5 CLDN5 ADD1 ADD1 XDH XDH VCL VCL ATOH8 ATOH8 GDF2 GDF2 ETV2 ETV2 APOLD1 APOLD1 TMEM100 TMEM100 ZEB1 ZEB1 NOTCH4 NOTCH4 JAG1 JAG1 CDH5 CDH5 ID1 ID1 PROC PROC TNFRSF1A TNFRSF1A FOXJ2 FOXJ2 ZDHHC21 ZDHHC21 IL1B IL1B S1PR3 S1PR3 CTNNB1 CTNNB1 IKBKB IKBKB BMP6 BMP6 BTG1 BTG1 PLCB1 PLCB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (229 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1482 aa)
ROCK1Rho associated coiled-coil containing protein kinase 1; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1322 aa)
F11RUncharacterized protein. (342 aa)
CLDN5Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (218 aa)
ADD1Adducin 1. (780 aa)
XDHXanthine dehydrogenase. (1258 aa)
VCLVinculin. (1147 aa)
ATOH8BHLH domain-containing protein. (328 aa)
GDF2TGF_BETA_2 domain-containing protein. (427 aa)
ETV2ETS domain-containing protein. (294 aa)
APOLD1Apolipoprotein L domain containing 1. (300 aa)
TMEM100Transmembrane protein 100. (114 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1116 aa)
NOTCH4Uncharacterized protein. (1975 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1276 aa)
CDH5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (722 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (150 aa)
PROCProtein C, inactivator of coagulation factors Va and VIIIa. (460 aa)
TNFRSF1AUncharacterized protein. (453 aa)
FOXJ2Forkhead box J2. (561 aa)
ZDHHC21Palmitoyltransferase; Belongs to the DHHC palmitoyltransferase family. (265 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
S1PR3Sphingosine-1-phosphate receptor 3; Belongs to the G-protein coupled receptor 1 family. (380 aa)
CTNNB1Catenin beta 1. (781 aa)
IKBKBInhibitor of nuclear factor kappa B kinase subunit beta. (693 aa)
BMP6Bone morphogenetic protein 6. (534 aa)
BTG1BTG anti-proliferation factor 1. (169 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1117 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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