(35 nodes) Positive regulation of carbohydrate metabolic process network (Monodelphis domestica)

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Your Input:
	APP	Amyloid beta precursor protein. (717 aa)
	PSEN1	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (516 aa)
	PRXL2C	Uncharacterized protein. (263 aa)
	MLXIPL	Uncharacterized protein. (260 aa)
	PTPN2	Tyrosine-protein phosphatase non-receptor type. (403 aa)
	EPM2AIP1	Uncharacterized protein. (614 aa)
	GPLD1	Glycosylphosphatidylinositol specific phospholipase D1. (900 aa)
	ENSMODP00000049100	Uncharacterized protein. (565 aa)
	GCK	Phosphotransferase. (532 aa)
	SORBS1	Sorbin and SH3 domain containing 1. (1277 aa)
	ADCYAP1R1	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family. (337 aa)
	KAT2A	Lysine acetyltransferase 2A. (712 aa)
	STK11	Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (414 aa)
	CD244	Ig-like domain-containing protein. (377 aa)
	F6XW95_MONDO	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (567 aa)
	P2RY6	Pyrimidinergic receptor P2Y6. (402 aa)
	KAT2B	Lysine acetyltransferase 2B. (862 aa)
	NFKB1	Nuclear factor kappa B subunit 1. (995 aa)
	DDB1	Damage specific DNA binding protein 1. (1026 aa)
	PRKAA1	Non-specific serine/threonine protein kinase. (559 aa)
	ZBTB20	Zinc finger and BTB domain containing 20. (749 aa)
	SIRT1	Deacetylase sirtuin-type domain-containing protein. (713 aa)
	INSR	Tyrosine-protein kinase receptor. (1378 aa)
	P2RX7	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family. (595 aa)
	HTR2A	5-hydroxytryptamine receptor 2A. (469 aa)
	PDGFB	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (235 aa)
	HIF1A	Hypoxia inducible factor 1 subunit alpha. (830 aa)
	PTH	Uncharacterized protein. (137 aa)
	ACTN3	Actinin alpha 3 (gene/pseudogene). (897 aa)
	MAS1	MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa)
	PPARA	Peroxisome proliferator activated receptor alpha. (468 aa)
	IGF1	Insulin like growth factor 1. (225 aa)
	AVPR1B	Vasopressin V1b receptor; Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate a phosphatidyl- inositol-calcium second messenger system. Belongs to the G-protein coupled receptor 1 family. Vasopressin/oxytocin receptor subfamily. (420 aa)
	SLC45A3	Solute carrier family 45 member 3. (552 aa)
	LHCGR	Lutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (700 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCYAP1R1	PTH	ENSMODP00000043365	ENSMODP00000010873	ADCYAP receptor type I; Belongs to the G-protein coupled receptor 2 family.	Uncharacterized protein.	0.403
APP	NFKB1	ENSMODP00000043145	ENSMODP00000025861	Amyloid beta precursor protein.	Nuclear factor kappa B subunit 1.	0.585
APP	PSEN1	ENSMODP00000043145	ENSMODP00000057945	Amyloid beta precursor protein.	Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family.	0.972
DDB1	SIRT1	ENSMODP00000025457	ENSMODP00000021523	Damage specific DNA binding protein 1.	Deacetylase sirtuin-type domain-containing protein.	0.406
F6XW95_MONDO	P2RY6	ENSMODP00000038449	ENSMODP00000032578	P2X purinoceptor; Receptor for ATP that acts as a ligand-gated ion channel. Belongs to the P2X receptor family.	Pyrimidinergic receptor P2Y6.	0.403
HIF1A	NFKB1	ENSMODP00000010901	ENSMODP00000025861	Hypoxia inducible factor 1 subunit alpha.	Nuclear factor kappa B subunit 1.	0.489
HIF1A	PPARA	ENSMODP00000010901	ENSMODP00000009135	Hypoxia inducible factor 1 subunit alpha.	Peroxisome proliferator activated receptor alpha.	0.453
HIF1A	SIRT1	ENSMODP00000010901	ENSMODP00000021523	Hypoxia inducible factor 1 subunit alpha.	Deacetylase sirtuin-type domain-containing protein.	0.532
IGF1	INSR	ENSMODP00000003043	ENSMODP00000018879	Insulin like growth factor 1.	Tyrosine-protein kinase receptor.	0.941
IGF1	PDGFB	ENSMODP00000003043	ENSMODP00000011942	Insulin like growth factor 1.	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	0.900
INSR	IGF1	ENSMODP00000018879	ENSMODP00000003043	Tyrosine-protein kinase receptor.	Insulin like growth factor 1.	0.941
INSR	PDGFB	ENSMODP00000018879	ENSMODP00000011942	Tyrosine-protein kinase receptor.	Platelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family.	0.693
INSR	PTPN2	ENSMODP00000018879	ENSMODP00000053467	Tyrosine-protein kinase receptor.	Tyrosine-protein phosphatase non-receptor type.	0.751
KAT2A	KAT2B	ENSMODP00000042376	ENSMODP00000032522	Lysine acetyltransferase 2A.	Lysine acetyltransferase 2B.	0.548
KAT2A	SIRT1	ENSMODP00000042376	ENSMODP00000021523	Lysine acetyltransferase 2A.	Deacetylase sirtuin-type domain-containing protein.	0.635
KAT2B	KAT2A	ENSMODP00000032522	ENSMODP00000042376	Lysine acetyltransferase 2B.	Lysine acetyltransferase 2A.	0.548
KAT2B	SIRT1	ENSMODP00000032522	ENSMODP00000021523	Lysine acetyltransferase 2B.	Deacetylase sirtuin-type domain-containing protein.	0.635
MLXIPL	PPARA	ENSMODP00000054084	ENSMODP00000009135	Uncharacterized protein.	Peroxisome proliferator activated receptor alpha.	0.438
NFKB1	APP	ENSMODP00000025861	ENSMODP00000043145	Nuclear factor kappa B subunit 1.	Amyloid beta precursor protein.	0.585
NFKB1	HIF1A	ENSMODP00000025861	ENSMODP00000010901	Nuclear factor kappa B subunit 1.	Hypoxia inducible factor 1 subunit alpha.	0.489