STRINGSTRING
ERCC4 ERCC4 PELP1 PELP1 PARP1 PARP1 TNKS2 TNKS2 MAU2 MAU2 NBN NBN EXOC5 EXOC5 EXOC2 EXOC2 MNAT1 MNAT1 PTH PTH BANF1 BANF1 PEX19 PEX19 RELA RELA F6RHZ7_MONDO F6RHZ7_MONDO MECP2 MECP2 SNF8 SNF8 HESX1 HESX1 TSC1 TSC1 SMARCE1 SMARCE1 DAXX DAXX EXOC4 EXOC4 YWHAQ YWHAQ VPS25 VPS25 RND2 RND2 NCOA3 NCOA3 F6WYG5_MONDO F6WYG5_MONDO HYPK HYPK PEX5 PEX5 ERCC3 ERCC3 PIAS3 PIAS3 ID1 ID1 CSNK2A1 CSNK2A1 TRAF6 TRAF6 NIPBL NIPBL ERCC2 ERCC2 NCOA1 NCOA1 STXBP1 STXBP1 GTF2H3 GTF2H3 ARF6 ARF6 PDCD10 PDCD10 F7FPN8_MONDO F7FPN8_MONDO BIVM BIVM F6QHP1_MONDO F6QHP1_MONDO F6VLZ9_MONDO F6VLZ9_MONDO ENSMODP00000041408 ENSMODP00000041408 THAP7 THAP7 PHB2 PHB2 ERCC5 ERCC5 SCFD1 SCFD1 ENSMODP00000042674 ENSMODP00000042674 DCTN4 DCTN4 NCOR2 NCOR2 CSNK2A2 CSNK2A2 ENSMODP00000044637 ENSMODP00000044637 ZWINT ZWINT CHMP6 CHMP6 EPB41 EPB41 ENSMODP00000048975 ENSMODP00000048975 ENSMODP00000050739 ENSMODP00000050739 ENSMODP00000050980 ENSMODP00000050980 ENSMODP00000052695 ENSMODP00000052695 MORF4L1 MORF4L1 ALG2 ALG2 RASSF1 RASSF1 SYNGR3 SYNGR3 SDCBP SDCBP ATM ATM ALOX5AP ALOX5AP H9H5V0_MONDO H9H5V0_MONDO LRP8 LRP8 GADD45A GADD45A SLC6A3 SLC6A3 SLA2 SLA2 SYNGR2 SYNGR2 CFAP36 CFAP36 ERCC6 ERCC6 PEX14 PEX14 SSPO SSPO FEZ1 FEZ1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ERCC4ERCC excision repair 4, endonuclease catalytic subunit. (897 aa)
PELP1Proline, glutamate and leucine rich protein 1. (1079 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
TNKS2Poly [ADP-ribose] polymerase. (1169 aa)
MAU2MAU2 sister chromatid cohesion factor. (604 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (748 aa)
EXOC5Exocyst complex component 5. (650 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (921 aa)
MNAT1CDK-activating kinase assembly factor MAT1; Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. (309 aa)
PTHUncharacterized protein. (137 aa)
BANF1Uncharacterized protein. (89 aa)
PEX19Uncharacterized protein. (296 aa)
RELARELA proto-oncogene, NF-kB subunit. (543 aa)
F6RHZ7_MONDOMRG domain-containing protein. (348 aa)
MECP2Methyl-CpG binding protein 2. (537 aa)
SNF8Vacuolar-sorting protein SNF8; Component of the endosomal sorting complex required for transport II (ESCRT-II), which is required for multivesicular body (MVB) formation and sorting of endosomal cargo proteins into MVBs. Belongs to the SNF8 family. (258 aa)
HESX1HESX homeobox 1. (189 aa)
TSC1TSC complex subunit 1. (1152 aa)
SMARCE1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily e, member 1. (440 aa)
DAXXDeath domain associated protein. (739 aa)
EXOC4Exocyst complex component 4. (975 aa)
YWHAQ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (245 aa)
VPS25Vacuolar protein sorting 25 homolog. (176 aa)
RND2Rho family GTPase 2. (231 aa)
NCOA3Nuclear receptor coactivator. (1400 aa)
F6WYG5_MONDOHCLS1-associated protein X-1; Recruits the Arp2/3 complex to the cell cortex and regulates reorganization of the cortical actin cytoskeleton via its interaction with KCNC3 and the Arp2/3 complex. Slows down the rate of inactivation of KCNC3 channels. Promotes GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. Promotes cell survival. May regulate intracellular calcium pools. (231 aa)
HYPKHuntingtin interacting protein K. (128 aa)
PEX5Peroxisomal biogenesis factor 5. (645 aa)
ERCC3ERCC excision repair 3, TFIIH core complex helicase subunit. (783 aa)
PIAS3Protein inhibitor of activated STAT 3. (629 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (150 aa)
CSNK2A1Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (448 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
NIPBLNipped-B protein. (2911 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
NCOA1Nuclear receptor coactivator 1. (1364 aa)
STXBP1Syntaxin binding protein 1; Belongs to the STXBP/unc-18/SEC1 family. (603 aa)
GTF2H3General transcription factor IIH subunit 3. (304 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
PDCD10Uncharacterized protein. (149 aa)
F7FPN8_MONDOMRG domain-containing protein. (242 aa)
BIVMUncharacterized protein. (504 aa)
F6QHP1_MONDOTelomerase reverse transcriptase; Telomerase is a ribonucleoprotein enzyme essential for the replication of chromosome termini in most eukaryotes. Active in progenitor and cancer cells. Inactive, or very low activity, in normal somatic cells. Catalytic component of the teleromerase holoenzyme complex whose main activity is the elongation of telomeres by acting as a reverse transcriptase that adds simple sequence repeats to chromosome ends by copying a template sequence within the RNA component of the enzyme. Catalyzes the RNA-dependent extension of 3'-chromosomal termini with the 6-nuc [...] (1274 aa)
F6VLZ9_MONDOUncharacterized protein. (89 aa)
ENSMODP00000041408Uncharacterized protein. (134 aa)
THAP7THAP domain containing 7. (314 aa)
PHB2Prohibitin. (299 aa)
ERCC5XPGI domain-containing protein. (694 aa)
SCFD1Sec1 family domain containing 1; Belongs to the STXBP/unc-18/SEC1 family. (612 aa)
ENSMODP00000042674Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (684 aa)
DCTN4Dynactin subunit 4. (467 aa)
NCOR2Nuclear receptor corepressor 2. (1970 aa)
CSNK2A2Casein kinase 2 alpha 2; Belongs to the protein kinase superfamily. (392 aa)
ENSMODP00000044637Uncharacterized protein. (101 aa)
ZWINTUncharacterized protein. (261 aa)
CHMP6Uncharacterized protein. (201 aa)
EPB41Erythrocyte membrane protein band 4.1. (919 aa)
ENSMODP0000004897514_3_3 domain-containing protein. (104 aa)
ENSMODP0000005073914_3_3 domain-containing protein; Belongs to the 14-3-3 family. (104 aa)
ENSMODP00000050980Uncharacterized protein. (3007 aa)
ENSMODP00000052695Uncharacterized protein. (143 aa)
MORF4L1Mortality factor 4 like 1. (483 aa)
ALG2Uncharacterized protein. (414 aa)
RASSF1Ras association domain family member 1. (367 aa)
SYNGR3MARVEL domain-containing protein. (400 aa)
SDCBPSyndecan binding protein. (311 aa)
ATMTAN domain-containing protein. (112 aa)
ALOX5APArachidonate 5-lipoxygenase activating protein. (162 aa)
H9H5V0_MONDOMARVEL domain-containing protein. (269 aa)
LRP8LDL receptor related protein 8. (854 aa)
GADD45AGrowth arrest and DNA damage inducible alpha. (168 aa)
SLC6A3Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (709 aa)
SLA2Src like adaptor 2. (289 aa)
SYNGR2MARVEL domain-containing protein. (391 aa)
CFAP36Cilia and flagella associated protein 36. (344 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1492 aa)
PEX14Peroxisomal biogenesis factor 14. (290 aa)
SSPOSCO-spondin. (4867 aa)
FEZ1Fasciculation and elongation protein zeta 1. (408 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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