STRINGSTRING
ENSMODP00000044407 ENSMODP00000044407 ENSMODP00000044115 ENSMODP00000044115 ALPK3-2 ALPK3-2 TNNI1 TNNI1 DLL4 DLL4 TSC1 TSC1 PDLIM5 PDLIM5 MYL10 MYL10 ENSMODP00000047497 ENSMODP00000047497 MEF2A MEF2A ENSMODP00000049183 ENSMODP00000049183 CAV3 CAV3 GATA6 GATA6 TNNC1 TNNC1 CXADR CXADR PTCD2 PTCD2 RYR2 RYR2 SMAD7 SMAD7 ENSMODP00000054808 ENSMODP00000054808 ENSMODP00000055638 ENSMODP00000055638 ENSMODP00000056667 ENSMODP00000056667 MTOR MTOR ARID2 ARID2 ATG5 ATG5 ENSMODP00000059630 ENSMODP00000059630 FOXH1 FOXH1 ENSMODP00000045476 ENSMODP00000045476 TBX3 TBX3 MYBPC3 MYBPC3 ACVR1 ACVR1 MEF2C MEF2C F7F0M1_MONDO F7F0M1_MONDO NKX2-5 NKX2-5 HNRNPU HNRNPU ANKRD1 ANKRD1 ACTN2 ACTN2 LRP2 LRP2 MYOCD MYOCD SGCG SGCG CHD7 CHD7 SGCD SGCD TGFB1 TGFB1 ALDH1A2 ALDH1A2 HAND1 HAND1 CSRP3 CSRP3 CBY1 CBY1 NRAP NRAP JARID2 JARID2 F7BA89_MONDO F7BA89_MONDO BMPR1A BMPR1A GJC1 GJC1 MYL2 MYL2 BMP10 BMP10 TBX5 TBX5 TAZ-2 TAZ-2 TGFBR1 TGFBR1 F6T0E2_MONDO F6T0E2_MONDO MED1 MED1 PKP2 PKP2 TCAP TCAP MYLK3 MYLK3 BMP4 BMP4 SAV1 SAV1 IRX3 IRX3 PRMT1 PRMT1 TBX2 TBX2 SLC9A1 SLC9A1 WNT2 WNT2 VWA5B1 VWA5B1 MYL7 MYL7 BMP7 BMP7 NPRL3 NPRL3 ADRA1A ADRA1A GATA5 GATA5 LMNA LMNA ZMPSTE24 ZMPSTE24 BVES BVES HEG1 HEG1 GJA5 GJA5 BMP5 BMP5 SRF SRF SGCZ SGCZ IFT20 IFT20 MYLK2 MYLK2 LOC100015455 LOC100015455 LRRC10B LRRC10B ALPK2 ALPK2 PDGFRA PDGFRA SIK1 SIK1 DIPK2A DIPK2A PPP1R13L PPP1R13L PLN PLN MAML1 MAML1 MYO18B MYO18B GREM1 GREM1 FOXC1 FOXC1 AKAP13 AKAP13 ALPK3 ALPK3 TAZ TAZ SMAD4 SMAD4 LRRC10 LRRC10 ACADM ACADM ITGB1 ITGB1 TBX20 TBX20 SMAD1 SMAD1 EDNRA EDNRA WNT2B WNT2B ASB2 ASB2 NOX4 NOX4 ADAMTS9 ADAMTS9 PROX1 PROX1 BMP2 BMP2 NEB NEB TGFB2 TGFB2 TENM4 TENM4 ZFPM2 ZFPM2 ENG ENG
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
ENSMODP00000044407Uncharacterized protein. (85 aa)
ENSMODP00000044115Uncharacterized protein. (357 aa)
ALPK3-2Ig-like domain-containing protein. (1205 aa)
TNNI1Troponin I1, slow skeletal type. (232 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (713 aa)
TSC1TSC complex subunit 1. (1152 aa)
PDLIM5PDZ and LIM domain 5. (592 aa)
MYL10Uncharacterized protein. (159 aa)
ENSMODP00000047497Uncharacterized protein. (405 aa)
MEF2AMyocyte enhancer factor 2A. (505 aa)
ENSMODP00000049183VIT domain-containing protein. (399 aa)
CAV3Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (242 aa)
GATA6GATA binding protein 6. (651 aa)
TNNC1Troponin C1, slow skeletal and cardiac type. (191 aa)
CXADRIg-like domain-containing protein. (279 aa)
PTCD2Pentatricopeptide repeat domain 2. (389 aa)
RYR2Ryanodine receptor 2. (4900 aa)
SMAD7Mothers against decapentaplegic homolog. (459 aa)
ENSMODP00000054808Uncharacterized protein. (101 aa)
ENSMODP00000055638Uncharacterized protein. (96 aa)
ENSMODP00000056667Uncharacterized protein. (160 aa)
MTORSerine/threonine-protein kinase mTOR. (1040 aa)
ARID2AT-rich interaction domain 2. (1836 aa)
ATG5Autophagy protein 5; Involved in autophagic vesicle formation. (277 aa)
ENSMODP00000059630Uncharacterized protein. (143 aa)
FOXH1Forkhead box H1. (413 aa)
ENSMODP00000045476Uncharacterized protein. (159 aa)
TBX3T-box transcription factor 3. (741 aa)
MYBPC3Myosin binding protein C, cardiac. (1220 aa)
ACVR1TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (559 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
F7F0M1_MONDOMH2 domain-containing protein. (347 aa)
NKX2-5NK2 homeobox 5. (319 aa)
HNRNPUHeterogeneous nuclear ribonucleoprotein U. (837 aa)
ANKRD1Ankyrin repeat domain 1. (319 aa)
ACTN2Actinin alpha 2. (894 aa)
LRP2LDL receptor related protein 2. (4605 aa)
MYOCDMyocardin. (903 aa)
SGCGSarcoglycan gamma. (313 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2999 aa)
SGCDSarcoglycan delta. (237 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
HAND1Heart and neural crest derivatives expressed 1. (212 aa)
CSRP3Cysteine and glycine rich protein 3. (232 aa)
CBY1Chibby family member 1, beta catenin antagonist. (127 aa)
NRAPNebulin related anchoring protein. (1762 aa)
JARID2Jumonji and AT-rich interaction domain containing 2. (1275 aa)
F7BA89_MONDOUncharacterized protein; Belongs to the PI3/PI4-kinase family. (740 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
GJC1Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (396 aa)
MYL2Myosin light chain 2. (166 aa)
BMP10Bone morphogenetic protein 10. (422 aa)
TBX5T-box transcription factor 5. (506 aa)
TAZ-2Tafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (235 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
F6T0E2_MONDOUncharacterized protein. (732 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1609 aa)
PKP2Plakophilin 2. (849 aa)
TCAPTitin-cap. (171 aa)
MYLK3Myosin light chain kinase 3. (846 aa)
BMP4Bone morphogenetic protein 4. (410 aa)
SAV1Salvador family WW domain containing protein 1. (397 aa)
IRX3Iroquois homeobox 3. (519 aa)
PRMT1Methyltransf_25 domain-containing protein; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (390 aa)
TBX2T-box transcription factor 2. (715 aa)
SLC9A1Sodium/hydrogen exchanger; Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. (392 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
VWA5B1Uncharacterized protein. (1286 aa)
MYL7Myosin light chain 7. (175 aa)
BMP7Bone morphogenetic protein 7. (432 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (579 aa)
ADRA1AAdrenoceptor alpha 1A. (465 aa)
GATA5GATA binding protein 5. (397 aa)
LMNALamin A/C; Belongs to the intermediate filament family. (663 aa)
ZMPSTE24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (476 aa)
BVESBlood vessel epicardial substance. (355 aa)
HEG1EGF-like domain-containing protein. (1126 aa)
GJA5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (356 aa)
BMP5Bone morphogenetic protein 5. (455 aa)
SRFSerum response factor. (490 aa)
SGCZSarcoglycan zeta. (307 aa)
IFT20Intraflagellar transport 20. (132 aa)
MYLK2Myosin light chain kinase 2. (623 aa)
LOC100015455BHLH domain-containing protein. (262 aa)
LRRC10BLeucine rich repeat containing 10B. (283 aa)
ALPK2Uncharacterized protein. (2169 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1085 aa)
SIK1Uncharacterized protein. (780 aa)
DIPK2ADivergent protein kinase domain 2A. (430 aa)
PPP1R13LProtein phosphatase 1 regulatory subunit 13 like. (781 aa)
PLNCardiac phospholamban; Reversibly inhibits the activity of ATP2A2 in cardiac sarcoplasmic reticulum by decreasing the apparent affinity of the ATPase for Ca(2+). Modulates the contractility of the heart muscle in response to physiological stimuli via its effects on ATP2A2. Modulates calcium re-uptake during muscle relaxation and plays an important role in calcium homeostasis in the heart muscle. The degree of ATP2A2 inhibition depends on the oligomeric state of PLN. (52 aa)
MAML1Mastermind like transcriptional coactivator 1. (1032 aa)
MYO18BMyosin XVIIIB; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2525 aa)
GREM1Gremlin. (184 aa)
FOXC1Fork-head domain-containing protein. (212 aa)
AKAP13Uncharacterized protein. (1424 aa)
ALPK3Alpha-type protein kinase domain-containing protein. (232 aa)
TAZTafazzin family protein; Some isoforms may be involved in cardiolipin metabolism. (364 aa)
SMAD4Mothers against decapentaplegic homolog. (534 aa)
LRRC10Uncharacterized protein. (285 aa)
ACADMAcyl-CoA dehydrogenase medium chain. (409 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (802 aa)
TBX20T-box transcription factor 20. (456 aa)
SMAD1Mothers against decapentaplegic homolog. (465 aa)
EDNRAEndothelin receptor type A; Belongs to the G-protein coupled receptor 1 family. (427 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (398 aa)
ASB2Ankyrin repeat and SOCS box containing 2. (672 aa)
NOX4NADPH oxidase 4. (578 aa)
ADAMTS9ADAM metallopeptidase with thrombospondin type 1 motif 9. (1333 aa)
PROX1Prospero homeobox 1. (782 aa)
BMP2Bone morphogenetic protein 2. (436 aa)
NEBNebulin. (6641 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
TENM4Teneurin transmembrane protein 4. (2632 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
ENGZP domain-containing protein. (654 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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