STRINGSTRING
APOE APOE MTA3 MTA3 HOXA5 HOXA5 PLCG1 PLCG1 KDM5B KDM5B LRG1 LRG1 UHRF1 UHRF1 HMOX1 HMOX1 SFRP2 SFRP2 WNT2B WNT2B PDCL3 PDCL3 MYC MYC GDF5 GDF5 RTN4 RTN4 IL10 IL10 TBC1D31 TBC1D31 IGF1 IGF1 PTCH1 PTCH1 PIK3CD PIK3CD VASH2 VASH2 TGM1 TGM1 PROX1 PROX1 ATP5F1A ATP5F1A JUN JUN GAS1 GAS1 VEGFC VEGFC BMP2 BMP2 B4GALT1 B4GALT1 F6VW21_MONDO F6VW21_MONDO LOC100018242 LOC100018242 APOH APOH TGFB2 TGFB2 FUT1 FUT1 HLX HLX DUSP10 DUSP10 FLCN FLCN SHH SHH ESRP2 ESRP2 SERPINB5 SERPINB5 VASH1 VASH1 NKX2-5 NKX2-5 F7BTQ8_MONDO F7BTQ8_MONDO ANG ANG C5AR2 C5AR2 ARX ARX SYNJ2BP SYNJ2BP GATA2 GATA2 CYP7B1 CYP7B1 VIP VIP FGFR2 FGFR2 XBP1 XBP1 TGFB1 TGFB1 ALDH1A2 ALDH1A2 SIX4 SIX4 KRT4 KRT4 C5AR1 C5AR1 TNMD TNMD PDX1 PDX1 SPARC SPARC EGFR EGFR FLT1 FLT1 ATF2 ATF2 MAP2K5 MAP2K5 PDGFB PDGFB ERRFI1 ERRFI1 BCL11B BCL11B RREB1 RREB1 BMP6 BMP6 SNAI2 SNAI2 WDR13 WDR13 ITGA4 ITGA4 SERPINF1 SERPINF1 OSR1 OSR1 FGFR1 FGFR1 KRIT1 KRIT1 HTR2B HTR2B ALOX5 ALOX5 ITGB3 ITGB3 ZNF703 ZNF703 BMPR1A BMPR1A RB1 RB1 CTNNB1 CTNNB1 PRL PRL IL12A IL12A TIE1 TIE1 GRN GRN TGFA TGFA BTK BTK F7FSS1_MONDO F7FSS1_MONDO STAT1 STAT1 NODAL NODAL CDC73 CDC73 AR AR NR4A3 NR4A3 TGFBR1 TGFBR1 NKX2-8 NKX2-8 MED1 MED1 BMP4 BMP4 DBH DBH NR1D1 NR1D1 NOD2 NOD2 SAV1 SAV1 APLN APLN SCN5A SCN5A HPN HPN FMC1 FMC1 PPARD PPARD TRIM24 TRIM24 PTN PTN DRD2 DRD2 KDF1 KDF1 SMO SMO ADAM17 ADAM17 CNMD CNMD STXBP4 STXBP4 CDH13 CDH13 TP63 TP63 ETV4 ETV4 GPC3 GPC3 IHH IHH IFT172 IFT172 MCC MCC NUPR1 NUPR1 TNF TNF WNT2 WNT2 CAV1 CAV1 BMPR2 BMPR2 IFT80 IFT80 NLRC3 NLRC3 DLX5 DLX5 PDPK1 PDPK1 GATA3 GATA3 NKX3-1 NKX3-1 PYGO2 PYGO2 SIRT1 SIRT1 TNFAIP3 TNFAIP3 PRKD1 PRKD1 ST8SIA1 ST8SIA1 IFT57 IFT57 CDKN1B CDKN1B EAF2 EAF2 A4GNT A4GNT LIMS2 LIMS2 FGF2 FGF2 VEGFA VEGFA CRNN CRNN ID1 ID1 THBS4 THBS4 PHOX2B PHOX2B AIMP1 AIMP1 KDR KDR LOC100017469 LOC100017469 ZNF580 ZNF580 F6PHR9_MONDO F6PHR9_MONDO NFIB NFIB HSF4 HSF4 JAG1 JAG1 EGR3 EGR3 F7C3T6_MONDO F7C3T6_MONDO NRARP NRARP F6TRY7_MONDO F6TRY7_MONDO LOC100009916 LOC100009916 F6VTF1_MONDO F6VTF1_MONDO SFN SFN F7F882_MONDO F7F882_MONDO ZEB1 ZEB1 BRCA2 BRCA2 IQGAP3 IQGAP3 F7AHA8_MONDO F7AHA8_MONDO F7GFG7_MONDO F7GFG7_MONDO PAX6 PAX6 PDCD10 PDCD10 SCG2 SCG2 AGTR1 AGTR1 PEX2 PEX2 VDR VDR STK11 STK11 LOC103096438 LOC103096438 ENSMODP00000041408 ENSMODP00000041408 BIRC5 BIRC5 DLL4 DLL4 ENSMODP00000041656 ENSMODP00000041656 PHB2 PHB2 ENSMODP00000041875 ENSMODP00000041875 STK3 STK3 ENSMODP00000042114 ENSMODP00000042114 APELA APELA AGGF1 AGGF1 ENSMODP00000043469 ENSMODP00000043469 THBS1 THBS1 BAD BAD MEF2C MEF2C WDR77 WDR77 LEP LEP CAV2 CAV2 IL26 IL26 CLDN1 CLDN1 JCAD JCAD F3 F3 CDKN2B CDKN2B FLT4 FLT4 GDF2 GDF2 ATOH8 ATOH8 CASK CASK MST1 MST1 PGF PGF BAX BAX CDK6 CDK6 STK4 STK4 XDH XDH CCND1 CCND1 FGF1 FGF1 IFT52 IFT52 LIMS1 LIMS1 ENSMODP00000050260 ENSMODP00000050260 EYA1 EYA1 RPTOR RPTOR ENSMODP00000051665 ENSMODP00000051665 TBX1 TBX1 DAB2 DAB2 STAT3 STAT3 APLNR APLNR DLX6 DLX6 TCF7L2 TCF7L2 DAB2IP DAB2IP EPGN EPGN MTSS1 MTSS1 FRS2 FRS2 INTU INTU CPB2 CPB2 ENSMODP00000055602 ENSMODP00000055602 ENSMODP00000055675 ENSMODP00000055675 PKHD1 PKHD1 GHRL GHRL PROK1 PROK1 JAML JAML IFT74 IFT74 TINF2 TINF2 OVOL1 OVOL1 PRKDC PRKDC NF1 NF1 PTPRK PTPRK AQP11 AQP11 RGCC RGCC MMRN2 MMRN2 EFNB2 EFNB2 WDR48 WDR48 SULF1 SULF1 LOC100030714 LOC100030714 FGF7 FGF7 VEGFB VEGFB NKX2-3 NKX2-3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
APOEUncharacterized protein. (299 aa)
MTA3Metastasis associated 1 family member 3. (609 aa)
HOXA5Homeobox A5. (269 aa)
PLCG11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1292 aa)
KDM5BLysine demethylase 5B. (1567 aa)
LRG1Uncharacterized protein. (356 aa)
UHRF1Ubiquitin like with PHD and ring finger domains 1. (787 aa)
HMOX1Uncharacterized protein. (290 aa)
SFRP2Secreted frizzled related protein 2. (295 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (398 aa)
PDCL3Phosducin like 3. (251 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa)
GDF5Growth differentiation factor 5. (495 aa)
RTN4Reticulon. (1217 aa)
IL10Interleukin 10. (173 aa)
TBC1D31TBC1 domain family member 31. (1075 aa)
IGF1Insulin like growth factor 1. (225 aa)
PTCH1Patched 1. (1521 aa)
PIK3CDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (959 aa)
VASH2Vasohibin 2. (332 aa)
TGM1Transglutaminase 1. (815 aa)
PROX1Prospero homeobox 1. (782 aa)
ATP5F1AATP synthase subunit alpha; Produces ATP from ADP in the presence of a proton gradient across the membrane. (553 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (344 aa)
GAS1Growth arrest specific 1. (373 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (351 aa)
BMP2Bone morphogenetic protein 2. (436 aa)
B4GALT1Uncharacterized protein. (384 aa)
F6VW21_MONDOCyclin_C domain-containing protein. (89 aa)
LOC100018242L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (348 aa)
APOHApolipoprotein H. (345 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
FUT1L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (333 aa)
HLXH2.0 like homeobox. (486 aa)
DUSP10Dual specificity phosphatase 10. (482 aa)
FLCNUDENN FLCN/SMCR8-type domain-containing protein. (579 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (480 aa)
ESRP2Epithelial splicing regulatory protein 2. (650 aa)
SERPINB5Serpin family B member 5; Belongs to the serpin family. (375 aa)
VASH1Vasohibin 1. (357 aa)
NKX2-5NK2 homeobox 5. (319 aa)
F7BTQ8_MONDOL-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (336 aa)
ANGAngiogenin; Belongs to the pancreatic ribonuclease family. (169 aa)
C5AR2Complement component 5a receptor 2. (352 aa)
ARXAristaless related homeobox. (537 aa)
SYNJ2BPSynaptojanin 2 binding protein. (145 aa)
GATA2GATA binding protein 2. (473 aa)
CYP7B1Uncharacterized protein; Belongs to the cytochrome P450 family. (462 aa)
VIPVasoactive intestinal peptide. (181 aa)
FGFR2Fibroblast growth factor receptor. (839 aa)
XBP1X-box binding protein 1. (204 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (518 aa)
SIX4SIX homeobox 4. (788 aa)
KRT4Keratin 4; Belongs to the intermediate filament family. (526 aa)
C5AR1G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (345 aa)
TNMDTenomodulin. (320 aa)
PDX1Homeobox domain-containing protein. (290 aa)
SPARCSecreted protein acidic and cysteine rich. (316 aa)
EGFRReceptor protein-tyrosine kinase. (1213 aa)
FLT1Fms related tyrosine kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1341 aa)
ATF2Cyclic AMP-dependent transcription factor ATF-2; Transcriptional activator which regulates the transcription of various genes, including those involved in anti-apoptosis, cell growth, and DNA damage response. Dependent on its binding partner, binds to CRE (cAMP response element) consensus sequences (5'-TGACGTCA- 3') or to AP-1 (activator protein 1) consensus sequences (5'-TGACTCA- 3'); Belongs to the bZIP family. (505 aa)
MAP2K5Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (448 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (235 aa)
ERRFI1ERBB receptor feedback inhibitor 1. (469 aa)
BCL11BBAF chromatin remodeling complex subunit BCL11B. (884 aa)
RREB1Ras responsive element binding protein 1. (1736 aa)
BMP6Bone morphogenetic protein 6. (534 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
WDR13WD repeat domain 13. (676 aa)
ITGA4Integrin subunit alpha 4; Belongs to the integrin alpha chain family. (1031 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (455 aa)
OSR1Odd-skipped related transcription factor 1. (265 aa)
FGFR1Fibroblast growth factor receptor. (809 aa)
KRIT1Uncharacterized protein. (736 aa)
HTR2B5-hydroxytryptamine receptor 2B; Belongs to the G-protein coupled receptor 1 family. (473 aa)
ALOX5Arachidonate 5-lipoxygenase. (674 aa)
ITGB3Integrin beta; Belongs to the integrin beta chain family. (784 aa)
ZNF703Zinc finger protein 703. (601 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
RB1RB transcriptional corepressor 1. (937 aa)
CTNNB1Catenin beta 1. (781 aa)
PRLProlactin; Prolactin acts primarily on the mammary gland by promoting lactation. (228 aa)
IL12AInterleukin-12 subunit alpha; Cytokine that can act as a growth factor for activated T and NK cells, enhance the lytic activity of NK/lymphokine-activated Killer cells, and stimulate the production of IFN-gamma by resting PBMC. (204 aa)
TIE1Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1138 aa)
GRNGranulin precursor. (581 aa)
TGFATransforming growth factor alpha. (159 aa)
BTKTyrosine-protein kinase. (655 aa)
F7FSS1_MONDOBRICHOS domain-containing protein. (180 aa)
STAT1Signal transducer and activator of transcription. (750 aa)
NODALNodal growth differentiation factor. (347 aa)
CDC73CDC73_N domain-containing protein. (371 aa)
ARAndrogen receptor. (960 aa)
NR4A3Nuclear receptor subfamily 4 group A member 3. (623 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
NKX2-8NK2 homeobox 8. (287 aa)
MED1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1609 aa)
BMP4Bone morphogenetic protein 4. (410 aa)
DBHDopamine beta-hydroxylase. (614 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (622 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (1012 aa)
SAV1Salvador family WW domain containing protein 1. (397 aa)
APLNUncharacterized protein. (204 aa)
SCN5ASodium channel protein; Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference across the membrane, the protein forms a sodium-selective channel through which Na(+) ions may pass in accordance with their electrochemical gradient. (1839 aa)
HPNHepsin; Belongs to the peptidase S1 family. (411 aa)
FMC1Formation of mitochondrial complex V assembly factor 1 homolog. (113 aa)
PPARDPeroxisome proliferator activated receptor delta. (441 aa)
TRIM24Tripartite motif containing 24. (1060 aa)
PTNPleiotrophin. (168 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (415 aa)
KDF1Keratinocyte differentiation factor 1. (415 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (785 aa)
ADAM17ADAM metallopeptidase domain 17. (747 aa)
CNMDChondromodulin. (335 aa)
STXBP4Syntaxin binding protein 4. (580 aa)
CDH13Cadherin 13. (711 aa)
TP63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (680 aa)
ETV4ETS variant 4. (478 aa)
GPC3Glypican 3; Cell surface proteoglycan that bears heparan sulfate. Belongs to the glypican family. (486 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
IFT172Intraflagellar transport 172. (1753 aa)
MCCMCC regulator of WNT signaling pathway. (828 aa)
NUPR1Uncharacterized protein. (82 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (229 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
CAV1Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
IFT80Intraflagellar transport 80. (721 aa)
NLRC3NLR family CARD domain containing 3. (1109 aa)
DLX5Distal-less homeobox 5. (292 aa)
PDPK13-phosphoinositide dependent protein kinase 1; Belongs to the protein kinase superfamily. (455 aa)
GATA3GATA binding protein 3. (444 aa)
NKX3-1NK3 homeobox 1. (258 aa)
PYGO2Pygopus family PHD finger 2. (369 aa)
SIRT1Deacetylase sirtuin-type domain-containing protein. (713 aa)
TNFAIP3TNF alpha induced protein 3. (796 aa)
PRKD1Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (861 aa)
ST8SIA1ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (426 aa)
IFT57Intraflagellar transport 57. (431 aa)
CDKN1BP27 protein. (199 aa)
EAF2ELL associated factor 2. (262 aa)
A4GNTAlpha-1,4-N-acetylglucosaminyltransferase. (329 aa)
LIMS2LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (341 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (156 aa)
VEGFAVascular endothelial growth factor A; Belongs to the PDGF/VEGF growth factor family. (445 aa)
CRNNEF-hand domain-containing protein. (627 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (150 aa)
THBS4Thrombospondin 4. (955 aa)
PHOX2BHomeobox domain-containing protein. (314 aa)
AIMP1Aminoacyl tRNA synthetase complex interacting multifunctional protein 1. (327 aa)
KDRKinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1349 aa)
LOC100017469Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1570 aa)
ZNF580Zinc finger protein 580. (169 aa)
F6PHR9_MONDOSEA domain-containing protein. (244 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (568 aa)
HSF4HSF_DOMAIN domain-containing protein. (534 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1276 aa)
EGR3Early growth response 3. (351 aa)
F7C3T6_MONDOUncharacterized protein. (506 aa)
NRARPNOTCH regulated ankyrin repeat protein. (114 aa)
F6TRY7_MONDOUncharacterized protein. (111 aa)
LOC100009916L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (335 aa)
F6VTF1_MONDOL-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (340 aa)
SFNStratifin; Belongs to the 14-3-3 family. (256 aa)
F7F882_MONDOUncharacterized protein. (115 aa)
ZEB1Zinc finger E-box binding homeobox 1. (1116 aa)
BRCA2Tower domain-containing protein. (3324 aa)
IQGAP3IQ motif containing GTPase activating protein 3. (1631 aa)
F7AHA8_MONDOToxin_TOLIP domain-containing protein. (133 aa)
F7GFG7_MONDOUncharacterized protein. (112 aa)
PAX6Paired box 6. (221 aa)
PDCD10Uncharacterized protein. (149 aa)
SCG2Secretogranin II. (624 aa)
AGTR1Angiotensin II receptor type 1; Belongs to the G-protein coupled receptor 1 family. (359 aa)
PEX2Peroxisomal biogenesis factor 2. (305 aa)
VDRUncharacterized protein. (289 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (414 aa)
LOC103096438Uncharacterized protein. (1013 aa)
ENSMODP00000041408Uncharacterized protein. (134 aa)
BIRC5Uncharacterized protein. (127 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (713 aa)
ENSMODP00000041656Uncharacterized protein. (270 aa)
PHB2Prohibitin. (299 aa)
ENSMODP00000041875L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (155 aa)
STK3Serine/threonine kinase 3. (555 aa)
ENSMODP00000042114SCY domain-containing protein. (97 aa)
APELAUncharacterized protein. (54 aa)
AGGF1Uncharacterized protein. (718 aa)
ENSMODP00000043469Uncharacterized protein. (80 aa)
THBS1Thrombospondin 1. (1197 aa)
BADUncharacterized protein. (212 aa)
MEF2CMyocyte enhancer factor 2C. (483 aa)
WDR77WD repeat domain 77. (432 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. In the hypothalamus, acts as an appetite-regulating factor that induces a decrease in food intake and an increase in energy consumption by inducing anorexinogenic factors and suppressing orexigenic neuropeptides, also regulates bone mass and secretion of hypothalamo- pituitary-adrenal hormones. In the periphery, increases basal me [...] (167 aa)
CAV2Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (162 aa)
IL26Uncharacterized protein. (171 aa)
CLDN1Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (211 aa)
JCADUncharacterized protein. (1516 aa)
F3Coagulation factor III, tissue factor. (268 aa)
CDKN2BANK_REP_REGION domain-containing protein. (138 aa)
FLT4Fms related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1337 aa)
GDF2TGF_BETA_2 domain-containing protein. (427 aa)
ATOH8BHLH domain-containing protein. (328 aa)
CASKCalcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (926 aa)
MST1Macrophage stimulating 1; Belongs to the peptidase S1 family. Plasminogen subfamily. (712 aa)
PGFPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (207 aa)
BAXUncharacterized protein. (296 aa)
CDK6Cyclin dependent kinase 6; Belongs to the protein kinase superfamily. (390 aa)
STK4Serine/threonine kinase 4. (496 aa)
XDHXanthine dehydrogenase. (1258 aa)
CCND1Uncharacterized protein. (67 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (181 aa)
IFT52Intraflagellar transport 52. (485 aa)
LIMS1LIM and senescent cell antigen-like-containing domain protein; Adapter protein in a cytoplasmic complex linking beta- integrins to the actin cytoskeleton, bridges the complex to cell surface receptor tyrosine kinases and growth factor receptors. (387 aa)
ENSMODP00000050260C-C motif chemokine. (121 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (628 aa)
RPTORRegulatory associated protein of MTOR complex 1. (1225 aa)
ENSMODP00000051665L-Fucosyltransferase; Belongs to the glycosyltransferase 11 family. (352 aa)
TBX1Uncharacterized protein. (512 aa)
DAB2DAB adaptor protein 2. (772 aa)
STAT3Signal transducer and activator of transcription. (805 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
DLX6Distal-less homeobox 6. (228 aa)
TCF7L2Transcription factor 7 like 2. (579 aa)
DAB2IPDAB2 interacting protein. (1180 aa)
EPGNEGF-like domain-containing protein. (152 aa)
MTSS1MTSS I-BAR domain containing 1. (797 aa)
FRS2IRS-type PTB domain-containing protein. (508 aa)
INTUInturned planar cell polarity protein. (898 aa)
CPB2Carboxypeptidase B2. (414 aa)
ENSMODP00000055602Uncharacterized protein. (451 aa)
ENSMODP00000055675Uncharacterized protein. (130 aa)
PKHD1PKHD1 ciliary IPT domain containing fibrocystin/polyductin. (4092 aa)
GHRLUncharacterized protein. (132 aa)
PROK1Prokineticin domain-containing protein. (105 aa)
JAMLIg-like domain-containing protein. (274 aa)
IFT74Intraflagellar transport 74. (657 aa)
TINF2TINF2_N domain-containing protein. (73 aa)
OVOL1Uncharacterized protein. (267 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4010 aa)
NF1Neurofibromin 1. (2781 aa)
PTPRKProtein tyrosine phosphatase receptor type K. (1471 aa)
AQP11Aquaporin; Aquaporins facilitate the transport of water and small neutral solutes across cell membranes. (290 aa)
RGCCRegulator of cell cycle. (183 aa)
MMRN2Uncharacterized protein. (997 aa)
EFNB2Ephrin RBD domain-containing protein; Belongs to the ephrin family. (333 aa)
WDR48WD repeat domain 48. (704 aa)
SULF1Sulfatase 1. (1125 aa)
LOC100030714Uncharacterized protein. (272 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (212 aa)
VEGFBPDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (568 aa)
NKX2-3NK2 homeobox 3. (345 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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