STRINGSTRING
SERPINE2 SERPINE2 FGF13 FGF13 DISC1 DISC1 PLXNB3 PLXNB3 RELN RELN RAPGEF2 RAPGEF2 GSX2 GSX2 ENSMODP00000055307 ENSMODP00000055307 TRIM32 TRIM32 ITPKA ITPKA PLXNA1 PLXNA1 PITX3 PITX3 ENSMODP00000057314 ENSMODP00000057314 NF1 NF1 LYN LYN REST REST MTOR MTOR FBXW8 FBXW8 PSEN1 PSEN1 CDK5 CDK5 DHX36 DHX36 UFL1 UFL1 ASCL1 ASCL1 BIN1 BIN1 DPYSL5 DPYSL5 MAPT MAPT TRAK1 TRAK1 LOC103099055 LOC103099055 NIN NIN SEMA3D SEMA3D TMEM98 TMEM98 EFNB3 EFNB3 ENSMODP00000060237 ENSMODP00000060237 S100A10 S100A10 OTP OTP LHX2 LHX2 F2 F2 LRP4 LRP4 PRPF19 PRPF19 NKX6-1 NKX6-1 SKI SKI HLTF HLTF L1CAM L1CAM AMIGO3 AMIGO3 GJC2 GJC2 NEFL NEFL PAFAH1B1 PAFAH1B1 SEMA4C SEMA4C AMIGO1 AMIGO1 TIAM2 TIAM2 DBN1 DBN1 SPEN SPEN ULK1 ULK1 HOXB3 HOXB3 EZH2 EZH2 BRAF BRAF PAX6 PAX6 PTPRZ1 PTPRZ1 SEMA3A SEMA3A NTRK2 NTRK2 PLXNA2 PLXNA2 CTDSP1 CTDSP1 SLITRK1 SLITRK1 LIG4 LIG4 SEMA5B SEMA5B SEMA7A SEMA7A F7A2H1_MONDO F7A2H1_MONDO F7ANH4_MONDO F7ANH4_MONDO LINGO1 LINGO1 ROBO2-2 ROBO2-2 F6U2S4_MONDO F6U2S4_MONDO GORASP1 GORASP1 K7E0A4_MONDO K7E0A4_MONDO STK11 STK11 ITGB1 ITGB1 DLL4 DLL4 ENSMODP00000041612 ENSMODP00000041612 EFNA5 EFNA5 ROBO2 ROBO2 STAU2 STAU2 ENSMODP00000042313 ENSMODP00000042313 ANAPC2 ANAPC2 HES2 HES2 CAPRIN1 CAPRIN1 WNT3 WNT3 ROBO1 ROBO1 JADE2 JADE2 FBXO31 FBXO31 NEURL1 NEURL1 HES7 HES7 SHANK3 SHANK3 SRRT SRRT ZFYVE27 ZFYVE27 BAIAP2 BAIAP2 MAG MAG HES6 HES6 ADNP ADNP NPTN NPTN MAP6 MAP6 CHODL CHODL ENSMODP00000045775 ENSMODP00000045775 KIFAP3 KIFAP3 BDNF BDNF XRCC2 XRCC2 SLC7A5 SLC7A5 SLIT2 SLIT2 XRCC5 XRCC5 SEMA6A SEMA6A FN1 FN1 TRPV2 TRPV2 MAP2 MAP2 PRUNE1 PRUNE1 DBNL DBNL PCM1 PCM1 SEMA4D SEMA4D PLXND1 PLXND1 SEMA5A SEMA5A FAIM FAIM DLL1 DLL1 METRN METRN TIAM1 TIAM1 PTPRD PTPRD SYNJ1 SYNJ1 ENSMODP00000050156 ENSMODP00000050156 PLXNB2 PLXNB2 ACY3 ACY3 CAPRIN2 CAPRIN2 ENSMODP00000051662 ENSMODP00000051662 TRIM46 TRIM46 PLXNA3 PLXNA3 RUFY3 RUFY3 ARNTL ARNTL RTN4 RTN4 MAP1B MAP1B FERD3L FERD3L MAN2A1 MAN2A1 IL6 IL6 DMRTA2 DMRTA2 WNT2B WNT2B F6YRI3_MONDO F6YRI3_MONDO GPR37L1 GPR37L1 CYFIP1 CYFIP1 LRP8 LRP8 LPAR3 LPAR3 SPINT1 SPINT1 TGM2 TGM2 SYT4 SYT4 EEF2K EEF2K NRP1 NRP1 WNT7B WNT7B ABCC8 ABCC8 NUMB NUMB HEY1 HEY1 F7G4H7_MONDO F7G4H7_MONDO LDLR LDLR TNR TNR SNW1 SNW1 TLX2 TLX2 NGF NGF SEMA4F SEMA4F TENM4 TENM4 HELT HELT SLIT1 SLIT1 SMARCD3 SMARCD3 VEGFC VEGFC PROX1 PROX1 RNF10 RNF10 NFATC4 NFATC4 E2F1 E2F1 SEMA6D SEMA6D FEZF2 FEZF2 GLI3 GLI3 IST1 IST1 APPL2 APPL2 LRP2 LRP2 PRTG PRTG LOC100020486 LOC100020486 OPRM1 OPRM1 CHD7 CHD7 TGFB1 TGFB1 FZD3 FZD3 HIF1A HIF1A DLX1 DLX1 DLX2 DLX2 LIF LIF DCT DCT PLXNC1 PLXNC1 ISLR ISLR ISLR2 ISLR2 SPART SPART HOOK3 HOOK3 SERPINF1 SERPINF1 CX3CR1 CX3CR1 ULK2 ULK2 NUMBL NUMBL DRAXIN DRAXIN F7BA89_MONDO F7BA89_MONDO BMPR1A BMPR1A RB1 RB1 CTNNB1 CTNNB1 GFAP GFAP SEMA3G SEMA3G ARHGAP4 ARHGAP4 MECP2 MECP2 SEMA4G SEMA4G IFRD2 IFRD2 SEMA3B SEMA3B CUX2 CUX2 SEMA3F SEMA3F ANKRD27 ANKRD27 SORL1 SORL1 NR1D1 NR1D1 THY1 THY1 DNAJB11 DNAJB11 GOLGA4 GOLGA4 CX3CL1 CX3CL1 ZNF335 ZNF335 WNT3A WNT3A IL1B IL1B LIMK1 LIMK1 PTN PTN SYNGAP1 SYNGAP1 WDR62 WDR62 DRD2 DRD2 LIN28A LIN28A IL34 IL34 PLXNB1 PLXNB1 DIXDC1 DIXDC1 LAYN LAYN SMO SMO RND2 RND2 FEZF1 FEZF1 TNF TNF WNT2 WNT2 IFRD1 IFRD1 KDM1A KDM1A BMPR2 BMPR2 BHLHE41 BHLHE41 SS18L1 SS18L1 SOX8 SOX8 SEMA4A SEMA4A SEMA3E SEMA3E SEMA3C SEMA3C EGR2 EGR2 CDKL5 CDKL5 HDAC1 HDAC1 FOXG1 FOXG1 HEYL HEYL HEY2 HEY2 ELL3 ELL3 HDAC2 HDAC2 NR2E1 NR2E1 RYK RYK SEMA6C SEMA6C FGF2 FGF2 SRF SRF ATOH1 ATOH1 ID1 ID1 SEMA4B SEMA4B IL6ST IL6ST NF2 NF2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SERPINE2Serpin family E member 2; Belongs to the serpin family. (469 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (249 aa)
DISC1Uncharacterized protein. (901 aa)
PLXNB3Plexin B3. (1937 aa)
RELNReelin. (3458 aa)
RAPGEF2Rap guanine nucleotide exchange factor 2. (1703 aa)
GSX2GS homeobox 2. (299 aa)
ENSMODP00000055307Caprin-1_dimer domain-containing protein. (282 aa)
TRIM32Tripartite motif containing 32. (605 aa)
ITPKAKinase; Belongs to the inositol phosphokinase (IPK) family. (516 aa)
PLXNA1Plexin A1. (1598 aa)
PITX3Homeobox protein. (305 aa)
ENSMODP00000057314Uncharacterized protein. (425 aa)
NF1Neurofibromin 1. (2781 aa)
LYNTyrosine-protein kinase. (516 aa)
RESTRE1 silencing transcription factor. (973 aa)
MTORSerine/threonine-protein kinase mTOR. (1040 aa)
FBXW8F-box and WD repeat domain containing 8. (575 aa)
PSEN1Presenilin; Probable subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors. Belongs to the peptidase A22A family. (516 aa)
CDK5Cyclin dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
DHX36DEAH-box helicase 36. (1009 aa)
UFL1UFM1 specific ligase 1. (794 aa)
ASCL1Achaete-scute family bHLH transcription factor 1. (299 aa)
BIN1Bridging integrator 1. (613 aa)
DPYSL5Dihydropyrimidinase like 5. (614 aa)
MAPTMicrotubule-associated protein. (1051 aa)
TRAK1Trafficking kinesin protein 1. (988 aa)
LOC103099055Uncharacterized protein; Belongs to the semaphorin family. (776 aa)
NINNinein. (1833 aa)
SEMA3DSemaphorin 3D; Belongs to the semaphorin family. (778 aa)
TMEM98Uncharacterized protein. (226 aa)
EFNB3Ephrin B3; Belongs to the ephrin family. (339 aa)
ENSMODP00000060237Uncharacterized protein. (623 aa)
S100A10EF-hand domain-containing protein; Belongs to the S-100 family. (97 aa)
OTPOrthopedia homeobox. (325 aa)
LHX2LIM homeobox 2. (408 aa)
F2Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (622 aa)
LRP4LDL receptor related protein 4. (1908 aa)
PRPF19Pre-mRNA processing factor 19. (504 aa)
NKX6-1NK6 homeobox 1. (376 aa)
SKISKI proto-oncogene. (677 aa)
HLTFHelicase like transcription factor. (1014 aa)
L1CAML1 cell adhesion molecule. (1230 aa)
AMIGO3Adhesion molecule with Ig like domain 3. (499 aa)
GJC2Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (405 aa)
NEFLNeurofilament light; Belongs to the intermediate filament family. (550 aa)
PAFAH1B1Platelet-activating factor acetylhydrolase IB subunit alpha; Positively regulates the activity of the minus-end directed microtubule motor protein dynein. May enhance dynein-mediated microtubule sliding by targeting dynein to the microtubule plus end. Required for several dynein- and microtubule-dependent processes such as the maintenance of Golgi integrity, the peripheral transport of microtubule fragments and the coupling of the nucleus and centrosome. Required during brain development for the proliferation of neuronal precursors and the migration of newly formed neurons from the ven [...] (409 aa)
SEMA4CUncharacterized protein; Belongs to the semaphorin family. (832 aa)
AMIGO1Adhesion molecule with Ig like domain 1. (493 aa)
TIAM2T cell lymphoma invasion and metastasis 2. (1726 aa)
DBN1Drebrin 1. (689 aa)
SPENSpen family transcriptional repressor. (3540 aa)
ULK1Unc-51 like autophagy activating kinase 1. (1013 aa)
HOXB3Homeobox B3. (297 aa)
EZH2Uncharacterized protein. (665 aa)
BRAFB-Raf proto-oncogene, serine/threonine kinase. (563 aa)
PAX6Paired box 6. (221 aa)
PTPRZ1Protein tyrosine phosphatase receptor type Z1. (1444 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (772 aa)
NTRK2Tyrosine-protein kinase receptor. (750 aa)
PLXNA2Plexin A2. (1875 aa)
CTDSP1CTD small phosphatase 1. (327 aa)
SLITRK1SLIT and NTRK like family member 1. (696 aa)
LIG4DNA ligase. (911 aa)
SEMA5BSemaphorin 5B. (1092 aa)
SEMA7ASemaphorin 7A (John Milton Hagen blood group); Belongs to the semaphorin family. (675 aa)
F7A2H1_MONDOUncharacterized protein. (624 aa)
F7ANH4_MONDOPlexin_cytopl domain-containing protein. (470 aa)
LINGO1Leucine rich repeat and Ig domain containing 1. (617 aa)
ROBO2-2Ig-like domain-containing protein. (121 aa)
F6U2S4_MONDODeacetylase sirtuin-type domain-containing protein. (261 aa)
GORASP1Golgi reassembly stacking protein 1. (407 aa)
K7E0A4_MONDOUncharacterized protein. (667 aa)
STK11Serine/threonine kinase 11; Belongs to the protein kinase superfamily. (414 aa)
ITGB1Integrin beta; Belongs to the integrin beta chain family. (802 aa)
DLL4Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (713 aa)
ENSMODP00000041612Uncharacterized protein. (83 aa)
EFNA5Ephrin A5; Belongs to the ephrin family. (228 aa)
ROBO2Roundabout guidance receptor 2. (1284 aa)
STAU2Staufen double-stranded RNA binding protein 2. (617 aa)
ENSMODP00000042313Uncharacterized protein. (84 aa)
ANAPC2Anaphase promoting complex subunit 2; Belongs to the cullin family. (826 aa)
HES2BHLH domain-containing protein. (77 aa)
CAPRIN1Cell cycle associated protein 1. (720 aa)
WNT3Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (358 aa)
ROBO1Roundabout guidance receptor 1. (1732 aa)
JADE2Jade family PHD finger 2. (864 aa)
FBXO31F-box protein 31. (609 aa)
NEURL1Neuralized E3 ubiquitin protein ligase 1. (577 aa)
HES7Hes family bHLH transcription factor 7. (227 aa)
SHANK3SH3 and multiple ankyrin repeat domains 3. (1695 aa)
SRRTSerrate, RNA effector molecule. (719 aa)
ZFYVE27Zinc finger FYVE-type containing 27. (403 aa)
BAIAP2BAI1 associated protein 2. (535 aa)
MAGMyelin associated glycoprotein. (626 aa)
HES6Uncharacterized protein. (308 aa)
ADNPActivity dependent neuroprotector homeobox. (1125 aa)
NPTNNeuroplastin. (420 aa)
MAP6Uncharacterized protein. (540 aa)
CHODLC-type lectin domain-containing protein. (298 aa)
ENSMODP00000045775SAM domain-containing protein. (300 aa)
KIFAP3Kinesin associated protein 3. (826 aa)
BDNFBrain-derived neurotrophic factor; During development, promotes the survival and differentiation of selected neuronal populations of the peripheral and central nervous systems. Participates in axonal growth, pathfinding and in the modulation of dendritic growth and morphology. Major regulator of synaptic transmission and plasticity at adult synapses in many regions of the CNS. (285 aa)
XRCC2X-ray repair cross complementing 2. (280 aa)
SLC7A5Solute carrier family 7 member 5. (533 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (701 aa)
SEMA6ASemaphorin 6A; Belongs to the semaphorin family. (1045 aa)
FN1Fibronectin 1. (2482 aa)
TRPV2Transient receptor potential cation channel subfamily V member 2; Belongs to the transient receptor (TC 1.A.4) family. (777 aa)
MAP2Microtubule-associated protein. (516 aa)
PRUNE1DHHA2 domain-containing protein. (473 aa)
DBNLDrebrin like. (430 aa)
PCM1Pericentriolar material 1. (2176 aa)
SEMA4DSemaphorin 4D; Belongs to the semaphorin family. (737 aa)
PLXND1Plexin D1. (1911 aa)
SEMA5ASemaphorin 5A. (1083 aa)
FAIMFas apoptotic inhibitory molecule. (280 aa)
DLL1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (734 aa)
METRNMeteorin, glial cell differentiation regulator. (298 aa)
TIAM1T cell lymphoma invasion and metastasis 1. (1575 aa)
PTPRDProtein tyrosine phosphatase receptor type D. (1912 aa)
SYNJ1Synaptojanin 1. (1536 aa)
ENSMODP00000050156Uncharacterized protein. (317 aa)
PLXNB2Sema domain-containing protein. (602 aa)
ACY3Uncharacterized protein. (411 aa)
CAPRIN2C1q domain-containing protein. (495 aa)
ENSMODP00000051662Uncharacterized protein. (321 aa)
TRIM46Tripartite motif containing 46. (502 aa)
PLXNA3Plexin A3. (1859 aa)
RUFY3RUN and FYVE domain containing 3. (511 aa)
ARNTLAryl hydrocarbon receptor nuclear translocator like. (696 aa)
RTN4Reticulon. (1217 aa)
MAP1BMicrotubule associated protein 1B. (2475 aa)
FERD3LFer3 like bHLH transcription factor. (180 aa)
MAN2A1Alpha-mannosidase. (1145 aa)
IL6Uncharacterized protein. (220 aa)
DMRTA2DMRT like family A2. (531 aa)
WNT2BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (398 aa)
F6YRI3_MONDOUncharacterized protein. (647 aa)
GPR37L1G protein-coupled receptor 37 like 1. (479 aa)
CYFIP1Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
LRP8LDL receptor related protein 8. (854 aa)
LPAR3Lysophosphatidic acid receptor 3; Belongs to the G-protein coupled receptor 1 family. (368 aa)
SPINT1Serine peptidase inhibitor, Kunitz type 1. (596 aa)
TGM2Transglutaminase 2. (689 aa)
SYT4Synaptotagmin 4. (426 aa)
EEF2KEukaryotic elongation factor 2 kinase. (724 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (922 aa)
WNT7BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
ABCC8ATP binding cassette subfamily C member 8. (1580 aa)
NUMBNUMB endocytic adaptor protein. (652 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (309 aa)
F7G4H7_MONDOFERM domain-containing protein. (482 aa)
LDLRLow density lipoprotein receptor. (906 aa)
TNRTenascin R. (1358 aa)
SNW1SNW domain containing 1. (536 aa)
TLX2T cell leukemia homeobox 2. (286 aa)
NGFNerve growth factor; Belongs to the NGF-beta family. (238 aa)
SEMA4FSsemaphorin 4F; Belongs to the semaphorin family. (795 aa)
TENM4Teneurin transmembrane protein 4. (2632 aa)
HELTHelt bHLH transcription factor. (242 aa)
SLIT1Slit guidance ligand 1. (1515 aa)
SMARCD3SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily d, member 3. (584 aa)
VEGFCVascular endothelial growth factor C; Belongs to the PDGF/VEGF growth factor family. (351 aa)
PROX1Prospero homeobox 1. (782 aa)
RNF10Ring finger protein 10. (782 aa)
NFATC4Nuclear factor of activated T cells 4. (902 aa)
E2F1E2F transcription factor 1. (443 aa)
SEMA6DSemaphorin 6D; Belongs to the semaphorin family. (1066 aa)
FEZF2FEZ family zinc finger 2. (487 aa)
GLI3GLI family zinc finger 3. (1501 aa)
IST1IST1 factor associated with ESCRT-III. (371 aa)
APPL2Adaptor protein, phosphotyrosine interacting with PH domain and leucine zipper 2. (663 aa)
LRP2LDL receptor related protein 2. (4605 aa)
PRTGProtogenin. (1148 aa)
LOC100020486Uncharacterized protein; Belongs to the parvalbumin family. (122 aa)
OPRM1Opioid receptor mu 1; Belongs to the G-protein coupled receptor 1 family. (401 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2999 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa)
FZD3Frizzled class receptor 3; Belongs to the G-protein coupled receptor Fz/Smo family. (666 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (830 aa)
DLX1Distal-less homeobox 1. (255 aa)
DLX2Distal-less homeobox 2. (329 aa)
LIFLIF interleukin 6 family cytokine. (202 aa)
DCTDopachrome tautomerase. (526 aa)
PLXNC1Plexin C1. (1582 aa)
ISLRImmunoglobulin superfamily containing leucine rich repeat. (418 aa)
ISLR2Immunoglobulin superfamily containing leucine rich repeat 2. (715 aa)
SPARTSpartin. (670 aa)
HOOK3Calponin-homology (CH) domain-containing protein. (445 aa)
SERPINF1Serpin family F member 1; Belongs to the serpin family. (455 aa)
CX3CR1C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
ULK2Unc-51 like autophagy activating kinase 2. (1041 aa)
NUMBLNUMB like endocytic adaptor protein. (689 aa)
DRAXINDraxin; Chemorepulsive axon guidance protein required for the development of spinal cord and forebrain commissures. Acts as a chemorepulsive guidance protein for commissural axons during development. Able to inhibit or repel neurite outgrowth from dorsal spinal cord. Inhibits the stabilization of cytosolic beta-catenin (CTNNB1) via its interaction with LRP6, thereby acting as an antagonist of Wnt signaling pathway. (338 aa)
F7BA89_MONDOUncharacterized protein; Belongs to the PI3/PI4-kinase family. (740 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
RB1RB transcriptional corepressor 1. (937 aa)
CTNNB1Catenin beta 1. (781 aa)
GFAPGlial fibrillary acidic protein; Belongs to the intermediate filament family. (428 aa)
SEMA3GSemaphorin 3G; Belongs to the semaphorin family. (760 aa)
ARHGAP4Uncharacterized protein. (698 aa)
MECP2Methyl-CpG binding protein 2. (537 aa)
SEMA4GSemaphorin 4G; Belongs to the semaphorin family. (840 aa)
IFRD2Interferon related developmental regulator 2. (437 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (764 aa)
CUX2Homeobox protein cut-like. (1468 aa)
SEMA3FSemaphorin 3F; Belongs to the semaphorin family. (726 aa)
ANKRD27Ankyrin repeat domain 27. (1063 aa)
SORL1Sortilin related receptor 1. (2218 aa)
NR1D1Nuclear receptor subfamily 1 group D member 1. (622 aa)
THY1Thy-1 cell surface antigen. (162 aa)
DNAJB11J domain-containing protein. (358 aa)
GOLGA4Golgin A4. (2142 aa)
CX3CL1SCY domain-containing protein. (409 aa)
ZNF335Zinc finger protein 335. (1365 aa)
WNT3AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (341 aa)
IL1BMultifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
LIMK1LIM domain kinase 1. (602 aa)
PTNPleiotrophin. (168 aa)
SYNGAP1Synaptic Ras GTPase activating protein 1. (1247 aa)
WDR62WD repeat domain 62. (1587 aa)
DRD2Dopamine receptor D2; Belongs to the G-protein coupled receptor 1 family. (415 aa)
LIN28ALin-28 homolog A. (205 aa)
IL34Uncharacterized protein. (279 aa)
PLXNB1Plexin B1. (2191 aa)
DIXDC1DIX domain containing 1. (681 aa)
LAYNLayilin. (391 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (785 aa)
RND2Rho family GTPase 2. (231 aa)
FEZF1FEZ family zinc finger 1. (465 aa)
TNFTumor necrosis factor; Belongs to the tumor necrosis factor family. (229 aa)
WNT2Protein Wnt-2; Ligand for members of the frizzled family of seven transmembrane receptors. Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Functions as upstream regulator of FGF10 expression. Plays an important role in embryonic lung development. May contribute to embryonic brain development by regulating the proliferation of dopaminergic precursors and neurons (By similarity). (360 aa)
IFRD1Interferon related developmental regulator 1. (447 aa)
KDM1ALysine demethylase 1A. (909 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
BHLHE41Basic helix-loop-helix family member e41. (501 aa)
SS18L1SS18L1 subunit of BAF chromatin remodeling complex. (402 aa)
SOX8SRY-box transcription factor 8. (474 aa)
SEMA4ASemaphorin 4A; Belongs to the semaphorin family. (790 aa)
SEMA3ESemaphorin 3E; Belongs to the semaphorin family. (715 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (753 aa)
EGR2Early growth response 2. (395 aa)
CDKL5Cyclin dependent kinase like 5. (945 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (450 aa)
FOXG1Forkhead box G1. (492 aa)
HEYLOrange domain-containing protein. (237 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (341 aa)
ELL3Elongation factor for RNA polymerase II 3. (385 aa)
HDAC2Histone deacetylase 2; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (488 aa)
NR2E1Nuclear receptor subfamily 2 group E member 1. (385 aa)
RYKReceptor like tyrosine kinase. (630 aa)
SEMA6CSemaphorin 6C; Belongs to the semaphorin family. (973 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (156 aa)
SRFSerum response factor. (490 aa)
ATOH1Atonal bHLH transcription factor 1. (380 aa)
ID1Inhibitor of DNA binding 1, HLH protein. (150 aa)
SEMA4BSemaphorin 4B; Belongs to the semaphorin family. (818 aa)
IL6STInterleukin 6 signal transducer. (923 aa)
NF2Neurofibromin 2. (595 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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