STRINGSTRING
K7E0V0_MONDO K7E0V0_MONDO ENSMODP00000060360 ENSMODP00000060360 ANXA3 ANXA3 ATM ATM BCL7A BCL7A ENSMODP00000059242 ENSMODP00000059242 SPIDR SPIDR ENSMODP00000059112 ENSMODP00000059112 INO80D INO80D IGF1R IGF1R ENSMODP00000059050 ENSMODP00000059050 WDR48 WDR48 YEATS4 YEATS4 ARID2 ARID2 RGCC RGCC DHX36 DHX36 ENSMODP00000057906 ENSMODP00000057906 PRKDC PRKDC DNMT3L DNMT3L CHTF18 CHTF18 ENSMODP00000056587 ENSMODP00000056587 ATRX ATRX ENSMODP00000056321 ENSMODP00000056321 ERCC1 ERCC1 CCT7 CCT7 ENSMODP00000055932 ENSMODP00000055932 ING3 ING3 ENSMODP00000055678 ENSMODP00000055678 ENSMODP00000055638 ENSMODP00000055638 KAT7 KAT7 KMT5B KMT5B ENSMODP00000055000 ENSMODP00000055000 ENSMODP00000054849 ENSMODP00000054849 ENSMODP00000054808 ENSMODP00000054808 ENSMODP00000053960 ENSMODP00000053960 TRRAP TRRAP ENSMODP00000053609 ENSMODP00000053609 HNRNPD HNRNPD BCL7C BCL7C ATR ATR HELQ HELQ IL2 IL2 MAPK15 MAPK15 ENSMODP00000051768 ENSMODP00000051768 RNF8 RNF8 EYA1 EYA1 CHTF8 CHTF8 SLF1 SLF1 ZCWPW1 ZCWPW1 PNKP PNKP ACTL6B ACTL6B ENSMODP00000049471 ENSMODP00000049471 SPIRE1 SPIRE1 ENSMODP00000049211 ENSMODP00000049211 BABAM2 BABAM2 NPM2 NPM2 BAX BAX UCHL5 UCHL5 EYA2 EYA2 SSBP1 SSBP1 MMS19 MMS19 CCT2 CCT2 XRCC5 XRCC5 POT1 POT1 FAM175A FAM175A RUVBL2 RUVBL2 ENSMODP00000044993 ENSMODP00000044993 MAP3K4 MAP3K4 ENSMODP00000044735 ENSMODP00000044735 ENSMODP00000044718 ENSMODP00000044718 TIGAR TIGAR ENSMODP00000044407 ENSMODP00000044407 HNRNPAB HNRNPAB ENSMODP00000043855 ENSMODP00000043855 ENSMODP00000043702 ENSMODP00000043702 MGMT MGMT FGFR4 FGFR4 ENSMODP00000042674 ENSMODP00000042674 ENSMODP00000042419 ENSMODP00000042419 EYA3 EYA3 TNKS TNKS MEAF6 MEAF6 TIMELESS TIMELESS K7E5G4_MONDO K7E5G4_MONDO K7E4L7_MONDO K7E4L7_MONDO K7E3N9_MONDO K7E3N9_MONDO K7E3J2_MONDO K7E3J2_MONDO K7E2X3_MONDO K7E2X3_MONDO NAF1 NAF1 K7E1G5_MONDO K7E1G5_MONDO RIF1 RIF1 K7E059_MONDO K7E059_MONDO K7E022_MONDO K7E022_MONDO K7DZY4_MONDO K7DZY4_MONDO K7DZX0_MONDO K7DZX0_MONDO K7DZW2_MONDO K7DZW2_MONDO K7DZV1_MONDO K7DZV1_MONDO K7DZN8_MONDO K7DZN8_MONDO K7DZG9_MONDO K7DZG9_MONDO K7DYU8_MONDO K7DYU8_MONDO K7DYR5_MONDO K7DYR5_MONDO K7DYQ9_MONDO K7DYQ9_MONDO TNFSF13 TNFSF13 WRN WRN PML PML EGF EGF PARP9 PARP9 F6Z480_MONDO F6Z480_MONDO GREM1 GREM1 DBF4 DBF4 DBF4B DBF4B HDGFL2 HDGFL2 FAM168A FAM168A F6Y4F4_MONDO F6Y4F4_MONDO WIZ WIZ PRDM7 PRDM7 BRPF3 BRPF3 F6YW13_MONDO F6YW13_MONDO F6TPY2_MONDO F6TPY2_MONDO UCN UCN TERF2 TERF2 GINS3 GINS3 STAT6 STAT6 BRCC3 BRCC3 ERCC2 ERCC2 F7G2T2_MONDO F7G2T2_MONDO SMCHD1 SMCHD1 ACTL6A ACTL6A RFC4 RFC4 E2F7 E2F7 FBXO4 FBXO4 ERCC8 ERCC8 ATAD5 ATAD5 PARM1 PARM1 EREG EREG FGF2 FGF2 POGZ POGZ VPS72 VPS72 PRIM2 PRIM2 RFC2 RFC2 RNF168 RNF168 TFRC TFRC DDX11 DDX11 DTX3L DTX3L RAD51AP1 RAD51AP1 TP53BP1 TP53BP1 MAPK1 MAPK1 F6VI96_MONDO F6VI96_MONDO DNA2 DNA2 FANCB FANCB SIRT1 SIRT1 HGF HGF CCT3 CCT3 MRGBP MRGBP PRKCQ PRKCQ SLX4 SLX4 PPP1R10 PPP1R10 PTK2B PTK2B NRM NRM INO80E INO80E MAPK3 MAPK3 F7EIL2_MONDO F7EIL2_MONDO EP400 EP400 RFC5 RFC5 BRCA1 BRCA1 BABAM1 BABAM1 MAP2K7 MAP2K7 F7E823_MONDO F7E823_MONDO EXOSC6 EXOSC6 RAD50 RAD50 MLH1 MLH1 BAZ1A BAZ1A PTPRC PTPRC MBTD1 MBTD1 TBX21 TBX21 ACTR8 ACTR8 BRD8 BRD8 F7CYR3_MONDO F7CYR3_MONDO MAPKAPK5 MAPKAPK5 CDC7 CDC7 F7AMB3_MONDO F7AMB3_MONDO PARP3 PARP3 PCNA PCNA MECP2 MECP2 GNL3 GNL3 CTNNB1 CTNNB1 MAD2L2 MAD2L2 PRKCD PRKCD F6ZF24_MONDO F6ZF24_MONDO GINS4 GINS4 LPIN1 LPIN1 WAS WAS UBE2V2 UBE2V2 RFC3 RFC3 WT1 WT1 KAT5 KAT5 PDGFB PDGFB DKC1 DKC1 EGFR EGFR E2F8 E2F8 TOX TOX TGFB1 TGFB1 CYP1B1 CYP1B1 CCDC117 CCDC117 HMCES HMCES RUVBL1 RUVBL1 CTC1 CTC1 STOML2 STOML2 NBN NBN EPC1 EPC1 MAS1 MAS1 WRAP53 WRAP53 F6XAI2_MONDO F6XAI2_MONDO FH FH DHX9 DHX9 RPS3 RPS3 TNKS2 TNKS2 PARP1 PARP1 SMOC2 SMOC2 USP7 USP7 ACD ACD HDAC10 HDAC10 NVL NVL NFRKB NFRKB UIMC1 UIMC1 PARN PARN BCAR3 BCAR3 GINS2 GINS2 SETMAR SETMAR MCRS1 MCRS1 NSD2 NSD2 TFPT TFPT TMEM161A TMEM161A CDT1 CDT1 DSCC1 DSCC1 F7ECV1_MONDO F7ECV1_MONDO POLG2 POLG2 APLF APLF EPC2 EPC2 SPIRE2 SPIRE2 ACTR2 ACTR2 EXOSC3 EXOSC3 CCT4 CCT4 NEK2 NEK2 NOX4 NOX4 SHLD2 SHLD2 DMAP1 DMAP1 ERCC6 ERCC6 CCT5 CCT5 FUS FUS MYC MYC MFSD11 MFSD11 IL6 IL6 FAF1 FAF1 MSH2 MSH2 F6YRU7_MONDO F6YRU7_MONDO PIAS4 PIAS4 PPARGC1A PPARGC1A OTUD4 OTUD4 RAD51 RAD51 MRE11 MRE11 INO80 INO80
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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K7E0V0_MONDOReverse transcriptase domain-containing protein. (756 aa)
ENSMODP00000060360SAE2 domain-containing protein. (81 aa)
ANXA3Annexin. (345 aa)
ATMTAN domain-containing protein. (112 aa)
BCL7AUncharacterized protein. (127 aa)
ENSMODP00000059242Uncharacterized protein. (151 aa)
SPIDRDUF4502 domain-containing protein. (235 aa)
ENSMODP00000059112Reverse transcriptase domain-containing protein. (955 aa)
INO80DINO80 complex subunit D. (1028 aa)
IGF1RTyrosine-protein kinase receptor. (1259 aa)
ENSMODP00000059050Reverse transcriptase domain-containing protein. (654 aa)
WDR48WD repeat domain 48. (704 aa)
YEATS4Uncharacterized protein. (227 aa)
ARID2AT-rich interaction domain 2. (1836 aa)
RGCCRegulator of cell cycle. (183 aa)
DHX36DEAH-box helicase 36. (1009 aa)
ENSMODP00000057906U1-type domain-containing protein. (438 aa)
PRKDCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4010 aa)
DNMT3LPHD-type domain-containing protein. (449 aa)
CHTF18Chromosome transmission fidelity factor 18. (937 aa)
ENSMODP00000056587Reverse transcriptase domain-containing protein. (914 aa)
ATRXATRX chromatin remodeler. (2389 aa)
ENSMODP00000056321Reverse transcriptase domain-containing protein. (956 aa)
ERCC1Uncharacterized protein. (436 aa)
CCT7T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. (623 aa)
ENSMODP00000055932Reverse transcriptase domain-containing protein. (1030 aa)
ING3Inhibitor of growth protein. (417 aa)
ENSMODP00000055678Uncharacterized protein. (57 aa)
ENSMODP00000055638Uncharacterized protein. (96 aa)
KAT7Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (614 aa)
KMT5BLysine methyltransferase 5B. (908 aa)
ENSMODP00000055000MPN domain-containing protein. (267 aa)
ENSMODP00000054849Uncharacterized protein; Belongs to the TCP-1 chaperonin family. (169 aa)
ENSMODP00000054808Uncharacterized protein. (101 aa)
ENSMODP00000053960KH type-2 domain-containing protein. (115 aa)
TRRAPTransformation/transcription domain associated protein; Belongs to the PI3/PI4-kinase family. (3796 aa)
ENSMODP00000053609SAE2 domain-containing protein. (75 aa)
HNRNPDHeterogeneous nuclear ribonucleoprotein D. (376 aa)
BCL7CBAF chromatin remodeling complex subunit BCL7C. (296 aa)
ATRUncharacterized protein. (159 aa)
HELQHelicase, POLQ like. (1099 aa)
IL2Interleukin-2; Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Belongs to the IL-2 family. (142 aa)
MAPK15Mitogen-activated protein kinase. (579 aa)
ENSMODP00000051768Reverse transcriptase domain-containing protein. (970 aa)
RNF8E3 ubiquitin-protein ligase RNF8; E3 ubiquitin-protein ligase that plays a key role in DNA damage signaling via 2 distinct roles: by mediating the 'Lys-63'-linked ubiquitination of histones H2A and H2AX and promoting the recruitment of DNA repair proteins at double-strand breaks (DSBs) sites, and by catalyzing 'Lys-48'-linked ubiquitination to remove target proteins from DNA damage sites. Following DNA DSBs, it is recruited to the sites of damage by ATM-phosphorylated MDC1 and catalyzes the 'Lys-63'-linked ubiquitination of histones H2A and H2AX, thereby promoting the formation of TP53 [...] (497 aa)
EYA1Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (628 aa)
CHTF8Chromosome transmission fidelity factor 8. (121 aa)
SLF1SMC5-SMC6 complex localization factor 1. (904 aa)
ZCWPW1CW-type domain-containing protein. (273 aa)
PNKPFHA_2 domain-containing protein. (592 aa)
ACTL6BActin like 6B; Belongs to the actin family. (474 aa)
ENSMODP00000049471Uncharacterized protein. (696 aa)
SPIRE1Spire type actin nucleation factor 1. (834 aa)
ENSMODP00000049211Reverse transcriptase domain-containing protein. (977 aa)
BABAM2BRISC and BRCA1 A complex member 2. (407 aa)
NPM2Nucleoplasmin domain-containing protein. (227 aa)
BAXUncharacterized protein. (296 aa)
UCHL5Ubiquitin carboxyl-terminal hydrolase. (369 aa)
EYA2Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (588 aa)
SSBP1Single stranded DNA binding protein 1. (178 aa)
MMS19MMS19 homolog, cytosolic iron-sulfur assembly component. (1116 aa)
CCT2Chaperonin containing TCP1 subunit 2. (571 aa)
XRCC5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (701 aa)
POT1Protection of telomeres 1. (746 aa)
FAM175AUncharacterized protein. (72 aa)
RUVBL2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (475 aa)
ENSMODP00000044993Uncharacterized protein. (58 aa)
MAP3K4Mitogen-activated protein kinase kinase kinase 4. (1621 aa)
ENSMODP00000044735Uncharacterized protein. (696 aa)
ENSMODP00000044718SAE2 domain-containing protein. (75 aa)
TIGARUncharacterized protein. (269 aa)
ENSMODP00000044407Uncharacterized protein. (85 aa)
HNRNPABHeterogeneous nuclear ribonucleoprotein A/B. (486 aa)
ENSMODP00000043855Reverse transcriptase domain-containing protein. (655 aa)
ENSMODP00000043702Reverse transcriptase domain-containing protein. (993 aa)
MGMTDNA_binding_1 domain-containing protein. (146 aa)
FGFR4Fibroblast growth factor receptor. (849 aa)
ENSMODP00000042674Nibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (684 aa)
ENSMODP00000042419Uncharacterized protein. (1127 aa)
EYA3Eyes absent homolog; Belongs to the HAD-like hydrolase superfamily. EYA family. (638 aa)
TNKSPoly [ADP-ribose] polymerase. (1442 aa)
MEAF6Uncharacterized protein. (484 aa)
TIMELESSTIMELESS domain-containing protein. (560 aa)
K7E5G4_MONDOReverse transcriptase domain-containing protein. (937 aa)
K7E4L7_MONDOReverse transcriptase domain-containing protein. (933 aa)
K7E3N9_MONDOReverse transcriptase domain-containing protein. (950 aa)
K7E3J2_MONDOReverse transcriptase domain-containing protein. (756 aa)
K7E2X3_MONDOUncharacterized protein. (589 aa)
NAF1Uncharacterized protein. (777 aa)
K7E1G5_MONDOReverse transcriptase domain-containing protein. (1005 aa)
RIF1Replication timing regulatory factor 1. (2408 aa)
K7E059_MONDOReverse transcriptase domain-containing protein. (940 aa)
K7E022_MONDOReverse transcriptase domain-containing protein. (1021 aa)
K7DZY4_MONDOReverse transcriptase domain-containing protein. (776 aa)
K7DZX0_MONDOReverse transcriptase domain-containing protein. (920 aa)
K7DZW2_MONDOReverse transcriptase domain-containing protein. (1006 aa)
K7DZV1_MONDOReverse transcriptase domain-containing protein. (973 aa)
K7DZN8_MONDOReverse transcriptase domain-containing protein. (756 aa)
K7DZG9_MONDOReverse transcriptase domain-containing protein. (943 aa)
K7DYU8_MONDOReverse transcriptase domain-containing protein. (939 aa)
K7DYR5_MONDOReverse transcriptase domain-containing protein. (741 aa)
K7DYQ9_MONDOReverse transcriptase domain-containing protein. (641 aa)
TNFSF13TNF_2 domain-containing protein; Belongs to the tumor necrosis factor family. (249 aa)
WRNWRN RecQ like helicase. (1333 aa)
PMLUncharacterized protein. (1118 aa)
EGFEpidermal growth factor. (1143 aa)
PARP9Uncharacterized protein. (777 aa)
F6Z480_MONDOUBIQUITIN_CONJUGAT_2 domain-containing protein. (145 aa)
GREM1Gremlin. (184 aa)
DBF4DBF4 zinc finger. (683 aa)
DBF4BDBF4-type domain-containing protein. (763 aa)
HDGFL2HDGF like 2. (769 aa)
FAM168AFamily with sequence similarity 168 member A. (258 aa)
F6Y4F4_MONDOUncharacterized protein. (2906 aa)
WIZUncharacterized protein. (1881 aa)
PRDM7KRAB-related domain-containing protein. (318 aa)
BRPF3Bromodomain and PHD finger containing 3. (1185 aa)
F6YW13_MONDODNA_MISMATCH_REPAIR_2 domain-containing protein. (641 aa)
F6TPY2_MONDOUncharacterized protein. (272 aa)
UCNUrocortin. (130 aa)
TERF2Telomeric repeat binding factor 2. (540 aa)
GINS3GINS complex subunit 3. (219 aa)
STAT6Signal transducer and activator of transcription. (839 aa)
BRCC3BRCA1/BRCA2-containing complex subunit 3. (261 aa)
ERCC2ERCC excision repair 2, TFIIH core complex helicase subunit. (760 aa)
F7G2T2_MONDOCtIP_N domain-containing protein. (683 aa)
SMCHD1SMC hinge domain-containing protein. (612 aa)
ACTL6AActin like 6A; Belongs to the actin family. (483 aa)
RFC4Replication factor C subunit 4. (435 aa)
E2F7E2F transcription factor 7. (1105 aa)
FBXO4F-box protein 4. (387 aa)
ERCC8ERCC excision repair 8, CSA ubiquitin ligase complex subunit. (396 aa)
ATAD5ATPase family AAA domain containing 5. (1875 aa)
PARM1Uncharacterized protein. (335 aa)
EREGEpiregulin. (179 aa)
FGF2Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. (156 aa)
POGZPogo transposable element derived with ZNF domain. (1409 aa)
VPS72Vacuolar protein sorting 72 homolog. (472 aa)
PRIM2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (508 aa)
RFC2Replication factor C subunit 2. (333 aa)
RNF168E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and H2AX and amplifies the RNF8-dependent H2A ubiquitination, promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recruitment of TP53BP1 and BRCA1. Also recrui [...] (572 aa)
TFRCTransferrin receptor. (771 aa)
DDX11DEAD/H-box helicase 11. (901 aa)
DTX3LRING-type domain-containing protein. (756 aa)
RAD51AP1RAD51_interact domain-containing protein. (373 aa)
TP53BP1Tumor protein p53 binding protein 1. (1882 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (359 aa)
F6VI96_MONDOUncharacterized protein. (202 aa)
DNA2DNA replication helicase/nuclease 2. (1060 aa)
FANCBFA complementation group B. (860 aa)
SIRT1Deacetylase sirtuin-type domain-containing protein. (713 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (729 aa)
CCT3T-complex protein 1 subunit gamma. (545 aa)
MRGBPUncharacterized protein. (231 aa)
PRKCQProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (695 aa)
SLX4BTB domain-containing protein. (1839 aa)
PPP1R10Protein phosphatase 1 regulatory subunit 10. (849 aa)
PTK2BProtein tyrosine kinase 2 beta; Belongs to the protein kinase superfamily. Tyr protein kinase family. (984 aa)
NRMUncharacterized protein. (115 aa)
INO80EINO80 complex subunit E. (245 aa)
MAPK3Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (380 aa)
F7EIL2_MONDOGIY-YIG domain-containing protein. (165 aa)
EP400E1A binding protein p400. (2929 aa)
RFC5Replication factor C subunit 5. (318 aa)
BRCA1Breast cancer type 1 susceptibility protein homolog; E3 ubiquitin-protein ligase that specifically mediates the formation of 'Lys-6'-linked polyubiquitin chains and plays a central role in DNA repair by facilitating cellular responses to DNA damage. It is unclear whether it also mediates the formation of other types of polyubiquitin chains. The E3 ubiquitin-protein ligase activity is required for its tumor suppressor function. The BRCA1-BARD1 heterodimer coordinates a diverse range of cellular pathways such as DNA damage repair, ubiquitination and transcriptional regulation to maintain [...] (1840 aa)
BABAM1Uncharacterized protein. (325 aa)
MAP2K7Mitogen-activated protein kinase kinase 7. (546 aa)
F7E823_MONDOProtein kinase domain-containing protein. (353 aa)
EXOSC6Exosome component 6. (255 aa)
RAD50Zinc-hook domain-containing protein. (1330 aa)
MLH1MutL homolog 1. (731 aa)
BAZ1ABromodomain adjacent to zinc finger domain 1A. (1556 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (1142 aa)
MBTD1FCS-type domain-containing protein. (618 aa)
TBX21T-box_assoc domain-containing protein. (575 aa)
ACTR8Actin-related protein 8; Plays an important role in the functional organization of mitotic chromosomes. Exhibits low basal ATPase activity, and unable to polymerize; Belongs to the actin family. ARP8 subfamily. (624 aa)
BRD8Bromodomain containing 8. (1316 aa)
F7CYR3_MONDOUncharacterized protein. (80 aa)
MAPKAPK5MAPK activated protein kinase 5. (473 aa)
CDC7Cell division cycle 7. (567 aa)
F7AMB3_MONDOUncharacterized protein. (923 aa)
PARP3Poly [ADP-ribose] polymerase. (530 aa)
PCNAProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (261 aa)
MECP2Methyl-CpG binding protein 2. (537 aa)
GNL3G protein nucleolar 3. (544 aa)
CTNNB1Catenin beta 1. (781 aa)
MAD2L2Mitotic arrest deficient 2 like 2. (223 aa)
PRKCDProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (677 aa)
F6ZF24_MONDOUncharacterized protein. (381 aa)
GINS4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (223 aa)
LPIN1Uncharacterized protein. (596 aa)
WASWASP actin nucleation promoting factor. (504 aa)
UBE2V2UBIQUITIN_CONJUGAT_2 domain-containing protein. (146 aa)
RFC3Replication factor C subunit 3. (356 aa)
WT1WT1 transcription factor. (473 aa)
KAT5Histone acetyltransferase; Belongs to the MYST (SAS/MOZ) family. (617 aa)
PDGFBPlatelet derived growth factor subunit B; Belongs to the PDGF/VEGF growth factor family. (235 aa)
DKC1Dyskerin pseudouridine synthase 1. (575 aa)
EGFRReceptor protein-tyrosine kinase. (1213 aa)
E2F8E2F transcription factor 8. (875 aa)
TOXThymocyte selection associated high mobility group box. (525 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa)
CYP1B1Cytochrome P450 family 1 subfamily B member 1; Belongs to the cytochrome P450 family. (545 aa)
CCDC117Coiled-coil domain containing 117. (276 aa)
HMCESAbasic site processing protein HMCES; Sensor of abasic sites in single-stranded DNA (ssDNA) required to preserve genome integrity by promoting error-free repair of abasic sites. Acts as an enzyme that recognizes and binds abasic sites in ssDNA at replication forks and chemically modifies the lesion by forming a covalent cross-link with DNA. The HMCES DNA-protein cross- link is then degraded by the proteasome. Promotes error-free repair of abasic sites by acting as a 'suicide' enzyme that is degraded, thereby protecting abasic sites from translesion synthesis (TLS) polymerases and endon [...] (330 aa)
RUVBL1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (456 aa)
CTC1CST telomere replication complex component 1. (1204 aa)
STOML2Stomatin like 2. (395 aa)
NBNNibrin; Component of the MRE11-RAD50-NBN (MRN complex) which plays a critical role in the cellular response to DNA damage and the maintenance of chromosome integrity. The complex is involved in double- strand break (DSB) repair, DNA recombination, maintenance of telomere integrity, cell cycle checkpoint control and meiosis. (748 aa)
EPC1Enhancer of polycomb homolog. (815 aa)
MAS1MAS1 proto-oncogene, G protein-coupled receptor; Belongs to the G-protein coupled receptor 1 family. (325 aa)
WRAP53WD_REPEATS_REGION domain-containing protein. (294 aa)
F6XAI2_MONDOUncharacterized protein. (137 aa)
FHFumarate hydratase. (504 aa)
DHX9DExH-box helicase 9. (1259 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
TNKS2Poly [ADP-ribose] polymerase. (1169 aa)
PARP1Poly [ADP-ribose] polymerase; Poly-ADP-ribosyltransferase that mediates poly-ADP- ribosylation of proteins and plays a key role in DNA repair. (1013 aa)
SMOC2SPARC related modular calcium binding 2. (482 aa)
USP7Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1053 aa)
ACDUncharacterized protein. (533 aa)
HDAC10Hist_deacetyl domain-containing protein. (306 aa)
NVLNuclear VCP like. (854 aa)
NFRKBNuclear factor related to kappaB binding protein. (1302 aa)
UIMC1Uncharacterized protein. (633 aa)
PARNPoly(A)-specific ribonuclease. (660 aa)
BCAR3BCAR3 adaptor protein, NSP family member. (826 aa)
GINS2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (185 aa)
SETMARUncharacterized protein. (288 aa)
MCRS1Microspherule protein 1. (462 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1392 aa)
TFPTTCF3 fusion partner. (246 aa)
TMEM161ATransmembrane protein 161A. (479 aa)
CDT1Chromatin licensing and DNA replication factor 1. (454 aa)
DSCC1DNA replication and sister chromatid cohesion 1. (420 aa)
F7ECV1_MONDOUncharacterized protein. (245 aa)
POLG2DNA polymerase gamma 2, accessory subunit. (481 aa)
APLFAprataxin and PNKP like factor. (488 aa)
EPC2Enhancer of polycomb homolog. (807 aa)
SPIRE2Spire type actin nucleation factor 2. (745 aa)
ACTR2Actin-related protein 2; ATP-binding component of the Arp2/3 complex, a multiprotein complex that mediates actin polymerization upon stimulation by nucleation-promoting factor (NPF). The Arp2/3 complex mediates the formation of branched actin networks in the cytoplasm, providing the force for cell motility. Seems to contact the pointed end of the daughter actin filament. (392 aa)
EXOSC3Exosome component 3. (275 aa)
CCT4T-complex protein 1 subunit delta. (547 aa)
NEK2NIMA related kinase 2. (445 aa)
NOX4NADPH oxidase 4. (578 aa)
SHLD2Shieldin complex subunit 2. (878 aa)
DMAP1DNA methyltransferase 1 associated protein 1. (462 aa)
ERCC6ERCC excision repair 6, chromatin remodeling factor. (1492 aa)
CCT5Chaperonin containing TCP1 subunit 5. (541 aa)
FUSFUS RNA binding protein. (528 aa)
MYCMyc proto-oncogene protein; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (435 aa)
MFSD11Major facilitator superfamily domain containing 11. (465 aa)
IL6Uncharacterized protein. (220 aa)
FAF1Fas associated factor 1. (643 aa)
MSH2DNA mismatch repair protein; Component of the post-replicative DNA mismatch repair system (MMR). (969 aa)
F6YRU7_MONDOUncharacterized protein. (198 aa)
PIAS4Protein inhibitor of activated STAT 4. (494 aa)
PPARGC1APPARG coactivator 1 alpha. (795 aa)
OTUD4OTU deubiquitinase 4. (1146 aa)
RAD51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (339 aa)
MRE11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (707 aa)
INO80INO80 complex ATPase subunit. (1558 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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