105 items (Monodelphis domestica) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	F6STE0_MONDO	Uncharacterized protein. (465 aa)
	ENSMODP00000050014	1-cysPrx_C domain-containing protein. (95 aa)
	MTPN	ANK_REP_REGION domain-containing protein. (118 aa)
	NOD1	Nucleotide binding oligomerization domain containing 1. (938 aa)
	LOC103101367	Uncharacterized protein. (211 aa)
	TLR9	TIR domain-containing protein. (1063 aa)
	LOC103102395	Uncharacterized protein. (207 aa)
	ROR1	Receptor tyrosine kinase like orphan receptor 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. ROR subfamily. (920 aa)
	BCL10	CARD domain-containing protein. (245 aa)
	CAT	Catalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Belongs to the catalase family. (529 aa)
	ENSMODP00000053960	KH type-2 domain-containing protein. (115 aa)
	TRIM37	Tripartite motif containing 37. (1037 aa)
	CARD11	Caspase recruitment domain family member 11. (1176 aa)
	TRIM32	Tripartite motif containing 32. (605 aa)
	IL1RAP	Interleukin 1 receptor accessory protein. (647 aa)
	UBE2V1	UBIQUITIN_CONJUGAT_2 domain-containing protein. (147 aa)
	IKBKB	Inhibitor of nuclear factor kappa B kinase subunit beta. (693 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (745 aa)
	CX3CR1	C-X3-C motif chemokine receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
	TRIM8	Tripartite motif containing 8. (359 aa)
	IRAK1	Interleukin 1 receptor associated kinase 1. (685 aa)
	AR	Androgen receptor. (960 aa)
	TRIM14	Tripartite motif containing 14. (443 aa)
	PSMA6	Proteasome subunit alpha type. (246 aa)
	NOD2	Nucleotide binding oligomerization domain containing 2. (1012 aa)
	SLCO3A1	Solute carrier organic anion transporter family member. (452 aa)
	CX3CL1	SCY domain-containing protein. (409 aa)
	IL1B	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family. (272 aa)
	F6R615_MONDO	Uncharacterized protein. (135 aa)
	TNFSF11	Tumor necrosis factor ligand superfamily member. (317 aa)
	AGER	Advanced glycosylation end-product specific receptor. (406 aa)
	PLCG2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1264 aa)
	RNF25	Ring finger protein 25. (510 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (229 aa)
	CAV1	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family. (178 aa)
	FLOT1	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (420 aa)
	F7ADI7_MONDO	Uncharacterized protein. (469 aa)
	IRAK3	Interleukin 1 receptor associated kinase 3. (591 aa)
	RIPK1	Receptor interacting serine/threonine kinase 1. (706 aa)
	RIPK2	Receptor interacting serine/threonine kinase 2. (540 aa)
	DHX9	DExH-box helicase 9. (1259 aa)
	RPS3	KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (243 aa)
	TRADD	TNFRSF1A associated via death domain. (361 aa)
	TNFRSF11A	TNFR-Cys domain-containing protein. (670 aa)
	TLR3	Toll like receptor 3; Belongs to the Toll-like receptor family. (905 aa)
	EDA	Ectodysplasin A; Belongs to the tumor necrosis factor family. (426 aa)
	TIRAP	TIR domain-containing protein. (342 aa)
	ANKRD42	Ankyrin repeat domain 42. (502 aa)
	F7DCX9_MONDO	B30.2/SPRY domain-containing protein. (285 aa)
	TRAF5	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (560 aa)
	F7CYW1_MONDO	Uncharacterized protein. (544 aa)
	F7EHK1_MONDO	Uncharacterized protein. (565 aa)
	IL18R1	Uncharacterized protein. (533 aa)
	F7DF74_MONDO	Uncharacterized protein. (368 aa)
	CARD14	Caspase recruitment domain family member 14. (973 aa)
	RAB7B	RAB7B, member RAS oncogene family. (200 aa)
	ZBTB7A	Zinc finger and BTB domain containing 7A. (508 aa)
	TRIM15	Tripartite motif containing 15. (469 aa)
	PRKCI	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (579 aa)
	RELA	RELA proto-oncogene, NF-kB subunit. (543 aa)
	DHX33	DEAH-box helicase 33. (681 aa)
	PRKCQ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (695 aa)
	NTRK1	Tyrosine-protein kinase receptor. (739 aa)
	TRIM62	Uncharacterized protein. (441 aa)
	RTKN2	Rhotekin 2. (591 aa)
	TRAF2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (633 aa)
	PRKD1	Serine/threonine-protein kinase; Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family. (861 aa)
	CARD9	Uncharacterized protein. (377 aa)
	TFRC	Transferrin receptor. (771 aa)
	CRNN	EF-hand domain-containing protein. (627 aa)
	FLOT2	Flotillin; Belongs to the band 7/mec-2 family. Flotillin subfamily. (504 aa)
	F6WC71_MONDO	Uncharacterized protein. (442 aa)
	CIB1	Calcium and integrin binding 1. (194 aa)
	RBCK1	RANBP2-type and C3HC4-type zinc finger containing 1. (516 aa)
	LOC103094639	B30.2/SPRY domain-containing protein. (259 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (540 aa)
	MALT1	MALT1 paracaspase. (789 aa)
	NTS	Neurotensin. (195 aa)
	RIPK4	Receptor interacting serine/threonine kinase 4. (794 aa)
	LOC100617582	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1107 aa)
	H9H9B2_MONDO	Uncharacterized protein. (277 aa)
	EIF2AK2	Uncharacterized protein. (651 aa)
	F6TPY2_MONDO	Uncharacterized protein. (272 aa)
	TRAF1	TNF receptor-associated factor. (380 aa)
	LOC103102863	Uncharacterized protein. (705 aa)
	GREM1	Gremlin. (184 aa)
	IRAK2	Interleukin 1 receptor associated kinase 2. (648 aa)
	ERC1	ELKS/RAB6-interacting/CAST family member 1. (1053 aa)
	F6TU13_MONDO	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (365 aa)
	F6TBX7_MONDO	Uncharacterized protein. (456 aa)
	PYCARD	PYD and CARD domain containing. (195 aa)
	EP300	E1A binding protein p300. (2454 aa)
	K7E1M2_MONDO	Uncharacterized protein; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (1138 aa)
	RNF31	Uncharacterized protein. (1157 aa)
	PRKCZ	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (589 aa)
	APP	Amyloid beta precursor protein. (717 aa)
	EDA2R	Ectodysplasin A2 receptor. (295 aa)
	DDRGK1	Uncharacterized protein. (309 aa)
	SPHK1	Sphingosine kinase 1. (454 aa)
	ENSMODP00000045309	Uncharacterized protein. (468 aa)
	ENSMODP00000045572	Uncharacterized protein. (50 aa)
	ARHGEF2	Rho/Rac guanine nucleotide exchange factor 2. (1219 aa)
	TRAPPC9	Trafficking protein particle complex 9. (1045 aa)
	PRDX3	Thioredoxin domain-containing protein. (268 aa)
	CD40LG	CD40 ligand; Cytokine that acts as a ligand to CD40/TNFRSF5. Costimulates T-cell proliferation and cytokine production. Involved in immunoglobulin class switching. (251 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGER	APP	ENSMODP00000018610	ENSMODP00000043145	Advanced glycosylation end-product specific receptor.	Amyloid beta precursor protein.	0.632
AGER	IL1B	ENSMODP00000018610	ENSMODP00000017267	Advanced glycosylation end-product specific receptor.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.458
AGER	TLR9	ENSMODP00000018610	ENSMODP00000050794	Advanced glycosylation end-product specific receptor.	TIR domain-containing protein.	0.411
AGER	TNF	ENSMODP00000018610	ENSMODP00000019686	Advanced glycosylation end-product specific receptor.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.442
APP	AGER	ENSMODP00000043145	ENSMODP00000018610	Amyloid beta precursor protein.	Advanced glycosylation end-product specific receptor.	0.632
APP	EP300	ENSMODP00000043145	ENSMODP00000037998	Amyloid beta precursor protein.	E1A binding protein p300.	0.640
APP	IL1B	ENSMODP00000043145	ENSMODP00000017267	Amyloid beta precursor protein.	Multifunctional fusion protein; Potent proinflammatory cytokine. Initially discovered as the major endogenous pyrogen, induces prostaglandin synthesis, neutrophil influx and activation, T-cell activation and cytokine production, B- cell activation and antibody production, and fibroblast proliferation and collagen production; Belongs to the IL-1 family.	0.461
APP	TNF	ENSMODP00000043145	ENSMODP00000019686	Amyloid beta precursor protein.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.440
AR	CAV1	ENSMODP00000015542	ENSMODP00000019745	Androgen receptor.	Caveolin; May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity; Belongs to the caveolin family.	0.492
AR	EP300	ENSMODP00000015542	ENSMODP00000037998	Androgen receptor.	E1A binding protein p300.	0.740
BCL10	CARD11	ENSMODP00000052151	ENSMODP00000054644	CARD domain-containing protein.	Caspase recruitment domain family member 11.	0.993
BCL10	CARD14	ENSMODP00000052151	ENSMODP00000002694	CARD domain-containing protein.	Caspase recruitment domain family member 14.	0.790
BCL10	CARD9	ENSMODP00000052151	ENSMODP00000021908	CARD domain-containing protein.	Uncharacterized protein.	0.991
BCL10	CHUK	ENSMODP00000052151	ENSMODP00000013213	CARD domain-containing protein.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.975
BCL10	IKBKB	ENSMODP00000052151	ENSMODP00000012792	CARD domain-containing protein.	Inhibitor of nuclear factor kappa B kinase subunit beta.	0.981
BCL10	MALT1	ENSMODP00000052151	ENSMODP00000025564	CARD domain-containing protein.	MALT1 paracaspase.	0.996
BCL10	PRKCQ	ENSMODP00000052151	ENSMODP00000020799	CARD domain-containing protein.	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.	0.820
BCL10	RELA	ENSMODP00000052151	ENSMODP00000011996	CARD domain-containing protein.	RELA proto-oncogene, NF-kB subunit.	0.541
BCL10	RIPK1	ENSMODP00000052151	ENSMODP00000010574	CARD domain-containing protein.	Receptor interacting serine/threonine kinase 1.	0.418
BCL10	RIPK2	ENSMODP00000052151	ENSMODP00000009583	CARD domain-containing protein.	Receptor interacting serine/threonine kinase 2.	0.421