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DHRS3 DHRS3 TGFBR1 TGFBR1 TBX2 TBX2 JAG2 JAG2 TGFBR2 TGFBR2 IFT172 IFT172 DLX5 DLX5 NPRL3 NPRL3 WFIKKN1 WFIKKN1 ARID5B ARID5B PYGO2 PYGO2 TCF21 TCF21 BBS7 BBS7 LEF1 LEF1 PDGFRA PDGFRA FRAS1 FRAS1 BCOR BCOR SMAD4 SMAD4 ALX4 ALX4 ENSMODP00000041663 ENSMODP00000041663 WNT9B WNT9B INSIG2 INSIG2 ENSMODP00000044573 ENSMODP00000044573 TBX3 TBX3 GABRB3 GABRB3 TBC1D32 TBC1D32 TBX1 TBX1 SNAI1 SNAI1 ENSMODP00000052470 ENSMODP00000052470 TMEM107 TMEM107 DLX6 DLX6 TFAP2A TFAP2A INTU INTU BNC2 BNC2 HAND2 HAND2 SUMO1 SUMO1 MEOX2 MEOX2 PKDCC PKDCC INSIG1 INSIG1 ITGB8 ITGB8 MSX1 MSX1 COL2A1 COL2A1 GLI3 GLI3 INHBA INHBA WDPCP WDPCP ANP32B ANP32B GAS1 GAS1 ITGB6 ITGB6 LRRC32 LRRC32 WNT11 WNT11 TGFB3 TGFB3 F7F0M1_MONDO F7F0M1_MONDO MSC MSC CHD7 CHD7 SGPL1 SGPL1 SOS1 SOS1 SNAI2 SNAI2 PAK1IP1 PAK1IP1 OSR1 OSR1 BMPR1A BMPR1A COL1A1 COL1A1 WFIKKN2 WFIKKN2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (275 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
TBX2T-box transcription factor 2. (715 aa)
JAG2Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1247 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (564 aa)
IFT172Intraflagellar transport 172. (1753 aa)
DLX5Distal-less homeobox 5. (292 aa)
NPRL3NPR3 like, GATOR1 complex subunit. (579 aa)
WFIKKN1WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 1. (553 aa)
ARID5BAT-rich interaction domain 5B. (1189 aa)
PYGO2Pygopus family PHD finger 2. (369 aa)
TCF21Transcription factor 21. (179 aa)
BBS7Bardet-Biedl syndrome 7 protein homolog; The BBSome complex is thought to function as a coat complex required for sorting of specific membrane proteins to the primary cilia. The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. (715 aa)
LEF1Lymphoid enhancer binding factor 1. (401 aa)
PDGFRAPlatelet-derived growth factor receptor alpha; Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development. (1085 aa)
FRAS1Uncharacterized protein. (3978 aa)
BCORBCL6 corepressor. (1722 aa)
SMAD4Mothers against decapentaplegic homolog. (534 aa)
ALX4ALX homeobox 4. (417 aa)
ENSMODP00000041663Uncharacterized protein. (668 aa)
WNT9BProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (427 aa)
INSIG2Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
ENSMODP00000044573Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (225 aa)
TBX3T-box transcription factor 3. (741 aa)
GABRB3Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (473 aa)
TBC1D32TBC1 domain family member 32. (1298 aa)
TBX1Uncharacterized protein. (512 aa)
SNAI1Uncharacterized protein. (259 aa)
ENSMODP00000052470Uncharacterized protein. (104 aa)
TMEM107Transmembrane protein 107. (140 aa)
DLX6Distal-less homeobox 6. (228 aa)
TFAP2ATranscription factor AP-2 alpha. (444 aa)
INTUInturned planar cell polarity protein. (898 aa)
BNC2Basonuclin 2. (1105 aa)
HAND2BHLH domain-containing protein. (217 aa)
SUMO1Ubiquitin-like domain-containing protein. (162 aa)
MEOX2Mesenchyme homeobox 2. (300 aa)
PKDCCProtein kinase domain containing, cytoplasmic. (490 aa)
INSIG1Insulin-induced gene protein; Mediates feedback control of cholesterol synthesis. Belongs to the INSIG family. (277 aa)
ITGB8Integrin beta; Belongs to the integrin beta chain family. (765 aa)
MSX1Msh homeobox 1. (314 aa)
COL2A1Collagen type II alpha 1 chain. (886 aa)
GLI3GLI family zinc finger 3. (1501 aa)
INHBAInhibin subunit beta A. (426 aa)
WDPCPWD repeat containing planar cell polarity effector. (720 aa)
ANP32BLRRcap domain-containing protein. (251 aa)
GAS1Growth arrest specific 1. (373 aa)
ITGB6Integrin beta; Belongs to the integrin beta chain family. (788 aa)
LRRC32Leucine rich repeat containing 32. (670 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (287 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (412 aa)
F7F0M1_MONDOMH2 domain-containing protein. (347 aa)
MSCMusculin. (219 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2999 aa)
SGPL1Sphingosine-1-phosphate lyase 1. (604 aa)
SOS1SOS Ras/Rac guanine nucleotide exchange factor 1. (1304 aa)
SNAI2Snail family transcriptional repressor 2. (268 aa)
PAK1IP1PAK1 interacting protein 1. (387 aa)
OSR1Odd-skipped related transcription factor 1. (265 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
COL1A1Collagen type I alpha 1 chain. (1430 aa)
WFIKKN2WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2. (567 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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