STRINGSTRING
TBX20 TBX20 PROX1 PROX1 NSD2 NSD2 FGFRL1 FGFRL1 ZFPM2 ZFPM2 WNT11 WNT11 ENG ENG F7F0M1_MONDO F7F0M1_MONDO NKX2-5 NKX2-5 HEY1 HEY1 NRP1 NRP1 LRP2 LRP2 CHD7 CHD7 HAND1 HAND1 SMAD6 SMAD6 BMPR1A BMPR1A GATA4 GATA4 TBX5 TBX5 DHRS3 DHRS3 TGFBR1 TGFBR1 SAV1 SAV1 TBX2 TBX2 SMO SMO MKS1 MKS1 TGFBR2 TGFBR2 BMPR2 BMPR2 BMP7 BMP7 SEMA3C SEMA3C HEYL HEYL HEY2 HEY2 BMP5 BMP5 JAG1 JAG1 CITED2 CITED2 SMAD4 SMAD4 ROBO2-2 ROBO2-2 ROBO2 ROBO2 ROBO1 ROBO1 ACVR1 ACVR1 CCN1 CCN1 TBX3 TBX3 SLIT2 SLIT2 SLIT3 SLIT3 NRP2 NRP2 TBX1 TBX1 GATA6 GATA6 APLNR APLNR FGF8 FGF8 SMAD7 SMAD7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TBX20T-box transcription factor 20. (456 aa)
PROX1Prospero homeobox 1. (782 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1392 aa)
FGFRL1Fibroblast growth factor receptor like 1. (494 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (287 aa)
ENGZP domain-containing protein. (654 aa)
F7F0M1_MONDOMH2 domain-containing protein. (347 aa)
NKX2-5NK2 homeobox 5. (319 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (309 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (922 aa)
LRP2LDL receptor related protein 2. (4605 aa)
CHD7Chromodomain helicase DNA binding protein 7. (2999 aa)
HAND1Heart and neural crest derivatives expressed 1. (212 aa)
SMAD6Mothers against decapentaplegic homolog. (503 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
GATA4GATA binding protein 4. (451 aa)
TBX5T-box transcription factor 5. (506 aa)
DHRS3Dehydrogenase/reductase 3; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (275 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
SAV1Salvador family WW domain containing protein 1. (397 aa)
TBX2T-box transcription factor 2. (715 aa)
SMOSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (785 aa)
MKS1MKS transition zone complex subunit 1. (574 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (564 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
BMP7Bone morphogenetic protein 7. (432 aa)
SEMA3CSemaphorin 3C; Belongs to the semaphorin family. (753 aa)
HEYLOrange domain-containing protein. (237 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (341 aa)
BMP5Bone morphogenetic protein 5. (455 aa)
JAG1Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1276 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (246 aa)
SMAD4Mothers against decapentaplegic homolog. (534 aa)
ROBO2-2Ig-like domain-containing protein. (121 aa)
ROBO2Roundabout guidance receptor 2. (1284 aa)
ROBO1Roundabout guidance receptor 1. (1732 aa)
ACVR1TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (559 aa)
CCN1Cellular communication network factor 1. (383 aa)
TBX3T-box transcription factor 3. (741 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
SLIT3Slit guidance ligand 3. (1532 aa)
NRP2Neuropilin; Belongs to the neuropilin family. (931 aa)
TBX1Uncharacterized protein. (512 aa)
GATA6GATA binding protein 6. (651 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (229 aa)
SMAD7Mothers against decapentaplegic homolog. (459 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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