STRINGSTRING
SMAD4 SMAD4 SMAD7 SMAD7 APLNR APLNR SLIT3 SLIT3 SLIT2 SLIT2 ACVR1 ACVR1 ROBO1 ROBO1 ROBO2 ROBO2 ROBO2-2 ROBO2-2 CITED2 CITED2 HEY2 HEY2 HEYL HEYL BMPR2 BMPR2 TGFBR2 TGFBR2 SAV1 SAV1 TGFBR1 TGFBR1 BMPR1A BMPR1A HEY1 HEY1 NKX2-5 NKX2-5 F7F0M1_MONDO F7F0M1_MONDO WNT11 WNT11 ZFPM2 ZFPM2 FGFRL1 FGFRL1 NSD2 NSD2 PROX1 PROX1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SMAD4Mothers against decapentaplegic homolog. (534 aa)
SMAD7Mothers against decapentaplegic homolog. (459 aa)
APLNRApelin receptor; Belongs to the G-protein coupled receptor 1 family. (384 aa)
SLIT3Slit guidance ligand 3. (1532 aa)
SLIT2Slit guidance ligand 2. (1542 aa)
ACVR1TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (559 aa)
ROBO1Roundabout guidance receptor 1. (1732 aa)
ROBO2Roundabout guidance receptor 2. (1284 aa)
ROBO2-2Ig-like domain-containing protein. (121 aa)
CITED2Cbp/p300 interacting transactivator with Glu/Asp rich carboxy-terminal domain 2. (246 aa)
HEY2Hes related family bHLH transcription factor with YRPW motif 2. (341 aa)
HEYLOrange domain-containing protein. (237 aa)
BMPR2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1035 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (564 aa)
SAV1Salvador family WW domain containing protein 1. (397 aa)
TGFBR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (552 aa)
BMPR1AReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (505 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (309 aa)
NKX2-5NK2 homeobox 5. (319 aa)
F7F0M1_MONDOMH2 domain-containing protein. (347 aa)
WNT11Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (287 aa)
ZFPM2Zinc finger protein, FOG family member 2. (1151 aa)
FGFRL1Fibroblast growth factor receptor like 1. (494 aa)
NSD2Nuclear receptor binding SET domain protein 2. (1392 aa)
PROX1Prospero homeobox 1. (782 aa)
Your Current Organism:
Monodelphis domestica
NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum
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