(14 nodes) Negative regulation of miRNA-mediated gene silencing network (Monodelphis domestica)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	ZC3H12A	Zinc finger CCCH-type containing 12A. (655 aa)
	IL6	Uncharacterized protein. (220 aa)
	HNF1A	HNF1 homeobox A. (613 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (424 aa)
	TNF	Tumor necrosis factor; Belongs to the tumor necrosis factor family. (229 aa)
	ESR1	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues. (589 aa)
	ZMPSTE24	CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (476 aa)
	LIN28B	Lin-28 homolog B. (295 aa)
	NCOR2	Nuclear receptor corepressor 2. (1970 aa)
	NCOR1	Nuclear receptor corepressor 1. (2417 aa)
	STAT3	Signal transducer and activator of transcription. (805 aa)
	DND1	DND microRNA-mediated repression inhibitor 1. (351 aa)
	BCDIN3D	Bin3-type SAM domain-containing protein. (276 aa)
	ELAVL1	ELAV-like protein; Belongs to the RRM elav family. (417 aa)

Your Current Organism:

Monodelphis domestica

NCBI taxonomy Id: 13616
Other names: gray short-tailed opossum

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ESR1	IL6	ENSMODP00000020873	ENSMODP00000001520	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Uncharacterized protein.	0.466
ESR1	NCOR1	ENSMODP00000020873	ENSMODP00000050088	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor corepressor 1.	0.909
ESR1	NCOR2	ENSMODP00000020873	ENSMODP00000043683	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Nuclear receptor corepressor 2.	0.900
ESR1	STAT3	ENSMODP00000020873	ENSMODP00000052576	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	Signal transducer and activator of transcription.	0.623
IL6	ESR1	ENSMODP00000001520	ENSMODP00000020873	Uncharacterized protein.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.466
IL6	STAT3	ENSMODP00000001520	ENSMODP00000052576	Uncharacterized protein.	Signal transducer and activator of transcription.	0.870
IL6	TGFB1	ENSMODP00000001520	ENSMODP00000010737	Uncharacterized protein.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.666
IL6	TNF	ENSMODP00000001520	ENSMODP00000019686	Uncharacterized protein.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.761
IL6	ZC3H12A	ENSMODP00000001520	ENSMODP00000022187	Uncharacterized protein.	Zinc finger CCCH-type containing 12A.	0.407
NCOR1	ESR1	ENSMODP00000050088	ENSMODP00000020873	Nuclear receptor corepressor 1.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.909
NCOR1	NCOR2	ENSMODP00000050088	ENSMODP00000043683	Nuclear receptor corepressor 1.	Nuclear receptor corepressor 2.	0.929
NCOR2	ESR1	ENSMODP00000043683	ENSMODP00000020873	Nuclear receptor corepressor 2.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.900
NCOR2	NCOR1	ENSMODP00000043683	ENSMODP00000050088	Nuclear receptor corepressor 2.	Nuclear receptor corepressor 1.	0.929
STAT3	ESR1	ENSMODP00000052576	ENSMODP00000020873	Signal transducer and activator of transcription.	Estrogen receptor; The steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.	0.623
STAT3	IL6	ENSMODP00000052576	ENSMODP00000001520	Signal transducer and activator of transcription.	Uncharacterized protein.	0.870
STAT3	TGFB1	ENSMODP00000052576	ENSMODP00000010737	Signal transducer and activator of transcription.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.505
STAT3	TNF	ENSMODP00000052576	ENSMODP00000019686	Signal transducer and activator of transcription.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.607
TGFB1	IL6	ENSMODP00000010737	ENSMODP00000001520	Transforming growth factor beta; Belongs to the TGF-beta family.	Uncharacterized protein.	0.666
TGFB1	STAT3	ENSMODP00000010737	ENSMODP00000052576	Transforming growth factor beta; Belongs to the TGF-beta family.	Signal transducer and activator of transcription.	0.505
TGFB1	TNF	ENSMODP00000010737	ENSMODP00000019686	Transforming growth factor beta; Belongs to the TGF-beta family.	Tumor necrosis factor; Belongs to the tumor necrosis factor family.	0.701