node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
AVP | LOC100026693 | ENSMODP00000006710 | ENSMODP00000006691 | Uncharacterized protein; Belongs to the vasopressin/oxytocin family. | Uncharacterized protein; Belongs to the vasopressin/oxytocin family. | 0.901 |
BRAF | F7E823_MONDO | ENSMODP00000034042 | ENSMODP00000018334 | B-Raf proto-oncogene, serine/threonine kinase. | Protein kinase domain-containing protein. | 0.581 |
BRAF | IQGAP3 | ENSMODP00000034042 | ENSMODP00000033667 | B-Raf proto-oncogene, serine/threonine kinase. | IQ motif containing GTPase activating protein 3. | 0.547 |
BRAF | MAPK1 | ENSMODP00000034042 | ENSMODP00000022098 | B-Raf proto-oncogene, serine/threonine kinase. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.581 |
BRAF | MAPK3 | ENSMODP00000034042 | ENSMODP00000019557 | B-Raf proto-oncogene, serine/threonine kinase. | Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. | 0.581 |
EDN1 | FGF2 | ENSMODP00000013239 | ENSMODP00000023577 | Endothelin 1. | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. | 0.519 |
EDN1 | KDR | ENSMODP00000013239 | ENSMODP00000025863 | Endothelin 1. | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.447 |
F7E823_MONDO | BRAF | ENSMODP00000018334 | ENSMODP00000034042 | Protein kinase domain-containing protein. | B-Raf proto-oncogene, serine/threonine kinase. | 0.581 |
FGF18 | FGF2 | ENSMODP00000057072 | ENSMODP00000023577 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. | 0.621 |
FGF18 | FGF23 | ENSMODP00000057072 | ENSMODP00000022822 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Fibroblast growth factor 23. | 0.728 |
FGF18 | KDR | ENSMODP00000057072 | ENSMODP00000025863 | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.821 |
FGF2 | EDN1 | ENSMODP00000023577 | ENSMODP00000013239 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. | Endothelin 1. | 0.519 |
FGF2 | FGF18 | ENSMODP00000023577 | ENSMODP00000057072 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.621 |
FGF2 | KDR | ENSMODP00000023577 | ENSMODP00000025863 | Fibroblast growth factor 2; Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Belongs to the heparin-binding growth factors family. | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.834 |
FGF23 | FGF18 | ENSMODP00000022822 | ENSMODP00000057072 | Fibroblast growth factor 23. | Fibroblast growth factor; Belongs to the heparin-binding growth factors family. | 0.728 |
FGF23 | KDR | ENSMODP00000022822 | ENSMODP00000025863 | Fibroblast growth factor 23. | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.814 |
IGF1 | KDR | ENSMODP00000003043 | ENSMODP00000025863 | Insulin like growth factor 1. | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.650 |
IQGAP3 | BRAF | ENSMODP00000033667 | ENSMODP00000034042 | IQ motif containing GTPase activating protein 3. | B-Raf proto-oncogene, serine/threonine kinase. | 0.547 |
ITGAV | KDR | ENSMODP00000013342 | ENSMODP00000025863 | Integrin subunit alpha V; Belongs to the integrin alpha chain family. | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | 0.431 |
KDR | EDN1 | ENSMODP00000025863 | ENSMODP00000013239 | Kinase insert domain receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. | Endothelin 1. | 0.447 |